We narrowed to 4,851 results for: U6...

1. pLentiCRISPR sgFTCD_2

   Plasmid

   #102313

   Purpose

   genetic depletion of FTCD

   Depositor

   David Sabatini

   Article

   Kanarek et al Nature. 2018 Jul 11. pii: 10.1038/s41586

   Insert

   sgFTCD_2 (FTCD Human)
   

   Use

   Lentiviral

   Tags

   Expression

   Mutation

   Promoter

   U6

   Available since

   July 13, 2018

   Availability

   Academic Institutions and Nonprofits only

   

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2. sgRNA2_NANOG

   Plasmid

   #64154

   Purpose

   Photoactivatable transcription system. Lentiviral expression of NANOG sgRNA2. Also contains a CMV-puro-t2A-mCherry expression cassette

   Depositor

   Moritoshi Sato

   Article

   Nihongaki et al Chem Biol. 2015 Feb 19;22(2):169-74. doi

   Insert

   sgRNA2_NANOG (NANOG Human)
   

   Use

   CRISPR and Lentiviral

   Tags

   Expression

   Mammalian

   Mutation

   Promoter

   U6

   Available since

   April 15, 2015

   Availability

   Academic Institutions and Nonprofits only

   

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3. pSicoR-ARID4Ai2

   Plasmid

   #59617

   Purpose

   Expression of shRNA against human ARID4A

   Depositor

   Miguel Ramalho-Santos

   Article

   Qin et al Cell. 2014 Jul 17;158(2):449-61. doi: 10

   Insert

   ARID4A (ARID4A Human)
   

   Use

   RNAi

   Tags

   Expression

   Mammalian

   Mutation

   Promoter

   U6

   Available since

   Sept. 29, 2014

   Availability

   Academic Institutions and Nonprofits only

4. pSicoR-ARID4Ai1

   Plasmid

   #59616

   Purpose

   Expression of shRNA against human ARID4A

   Depositor

   Miguel Ramalho-Santos

   Article

   Qin et al Cell. 2014 Jul 17;158(2):449-61. doi: 10

   Insert

   ARID4A (ARID4A Human)
   

   Use

   RNAi

   Tags

   Expression

   Mammalian

   Mutation

   Promoter

   U6

   Available since

   Sept. 29, 2014

   Availability

   Academic Institutions and Nonprofits only

5. APq5210

   Plasmid

   #66086

   Purpose

   co-expression of Cas9 and a sgRNA targeting K08F4.2 in the middle of the ORF

   Depositor

   Geraldine Seydoux

   Article

   Paix et al Genetics. 2014 Dec;198(4):1347-56. doi:

   Insert

   sgRNA for APa4-2
   

   Use

   CRISPR

   Tags

   Expression

   Worm

   Mutation

   Promoter

   U6

   Available since

   June 25, 2015

   Availability

   Academic Institutions and Nonprofits only

6. pSicoR-ADAM7i1

   Plasmid

   #59602

   Purpose

   Expression of shRNA against human ADAM7

   Depositor

   Miguel Ramalho-Santos

   Article

   Qin et al Cell. 2014 Jul 17;158(2):449-61. doi: 10

   Insert

   ADAM7 (ADAM7 Human)
   

   Use

   RNAi

   Tags

   Expression

   Mammalian

   Mutation

   Promoter

   U6

   Available since

   Sept. 26, 2014

   Availability

   Academic Institutions and Nonprofits only

7. pKLV2-U6gRNA5(hMTOR_1k)-PGKpuro2ABFP-W

   Plasmid

   #208429

   Purpose

   Lentiviral gRNA plasmid targeting human MTOR gene, co-expression of BFP tag

   Depositor

   Sok Ching Cheong

   Article

   Chai et al Heliyon. 2024 Oct 22;10(21):e39677. doi:

   Insert

   MTOR (MTOR Human)
   

   Use

   CRISPR and Lentiviral

   Tags

   Expression

   Mammalian

   Mutation

   N/A

   Promoter

   human U6

   Available since

   July 1, 2025

   Availability

   Academic Institutions and Nonprofits only

   

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8. pKLV2-U6gRNA5(hMTOR_2b)-PGKpuro2ABFP-W

   Plasmid

   #208430

   Purpose

   Lentiviral gRNA plasmid targeting human MTOR gene, co-expression of BFP tag

   Depositor

   Sok Ching Cheong

   Article

   Chai et al Heliyon. 2024 Oct 22;10(21):e39677. doi:

   Insert

   MTOR (MTOR Human)
   

   Use

   CRISPR and Lentiviral

   Tags

   Expression

   Mammalian

   Mutation

   N/A

   Promoter

   human U6

   Available since

   July 1, 2025

   Availability

   Academic Institutions and Nonprofits only

   

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9. RhoA gRNA #1

   Plasmid

   #198718

   Purpose

   Cas9-mediated knockout of RhoA in mammalian cells #1

   Depositor

   Takeshi Imai

   Article

   Fujimoto et al Dev Cell. 2023 Jul 24;58(14):1221-1236.e

   Insert

   RhoA (Rhoa Mouse)
   

   Use

   CRISPR

   Tags

   Expression

   Mammalian

   Mutation

   Promoter

   U6

   Available since

   Dec. 11, 2024

   Availability

   Academic Institutions and Nonprofits only

   

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10. RhoA gRNA #3

    Plasmid

    #198720

    Purpose

    Cas9-mediated knockout of RhoA in mammalian cells #3

    Depositor

    Takeshi Imai

    Article

    Fujimoto et al Dev Cell. 2023 Jul 24;58(14):1221-1236.e

    Insert

    RhoA (Rhoa Mouse)
    

    Use

    CRISPR

    Tags

    Expression

    Mammalian

    Mutation

    Promoter

    U6

    Available since

    Dec. 11, 2024

    Availability

    Academic Institutions and Nonprofits only

    

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11. RhoB gRNA #1

    Plasmid

    #198721

    Purpose

    Cas9-mediated knockout of RhoB in mammalian cells #1

    Depositor

    Takeshi Imai

    Article

    Fujimoto et al Dev Cell. 2023 Jul 24;58(14):1221-1236.e

    Insert

    RhoB (Rhob Mouse)
    

    Use

    CRISPR

    Tags

    Expression

    Mammalian

    Mutation

    Promoter

    U6

    Available since

    Dec. 11, 2024

    Availability

    Academic Institutions and Nonprofits only

    

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12. RhoB gRNA #2

    Plasmid

    #198722

    Purpose

    Cas9-mediated knockout of RhoB in mammalian cells #2

    Depositor

    Takeshi Imai

    Article

    Fujimoto et al Dev Cell. 2023 Jul 24;58(14):1221-1236.e

    Insert

    RhoB (Rhob Mouse)
    

    Use

    CRISPR

    Tags

    Expression

    Mammalian

    Mutation

    Promoter

    U6

    Available since

    Dec. 11, 2024

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

13. RhoB gRNA #3

    Plasmid

    #198723

    Purpose

    Cas9-mediated knockout of RhoB in mammalian cells #3

    Depositor

    Takeshi Imai

    Article

    Fujimoto et al Dev Cell. 2023 Jul 24;58(14):1221-1236.e

    Insert

    RhoB (Rhob Mouse)
    

    Use

    CRISPR

    Tags

    Expression

    Mammalian

    Mutation

    Promoter

    U6

    Available since

    Dec. 11, 2024

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

14. RhoC gRNA #1

    Plasmid

    #198724

    Purpose

    Cas9-mediated knockout of RhoC in mammalian cells #1

    Depositor

    Takeshi Imai

    Article

    Fujimoto et al Dev Cell. 2023 Jul 24;58(14):1221-1236.e

    Insert

    RhoC (Rhoc Mouse)
    

    Use

    CRISPR

    Tags

    Expression

    Mammalian

    Mutation

    Promoter

    U6

    Available since

    Dec. 11, 2024

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

15. RhoC gRNA #2

    Plasmid

    #198725

    Purpose

    Cas9-mediated knockout of RhoC in mammalian cells #2

    Depositor

    Takeshi Imai

    Article

    Fujimoto et al Dev Cell. 2023 Jul 24;58(14):1221-1236.e

    Insert

    RhoC (Rhoc Mouse)
    

    Use

    CRISPR

    Tags

    Expression

    Mammalian

    Mutation

    Promoter

    U6

    Available since

    Dec. 11, 2024

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

16. RhoC gRNA #3

    Plasmid

    #198726

    Purpose

    Cas9-mediated knockout of RhoC in mammalian cells #3

    Depositor

    Takeshi Imai

    Article

    Fujimoto et al Dev Cell. 2023 Jul 24;58(14):1221-1236.e

    Insert

    RhoC (Rhoc Mouse)
    

    Use

    CRISPR

    Tags

    Expression

    Mammalian

    Mutation

    Promoter

    U6

    Available since

    Dec. 11, 2024

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

17. pX552-DIO-NLS-mRuby3(with gRNA scaffold)

    Plasmid

    #199583

    Purpose

    Expresses NLS-mRuby3 in a Cre-dependent manner

    Depositor

    Bryan Copits

    Article

    Moffa et al eNeuro. 2024 Jul 5;11(7):ENEURO.0438-23.

    Insert

    NLS-mRuby3
    

    Use

    AAV, CRISPR, and Cre/Lox

    Tags

    Expression

    Mammalian

    Mutation

    Promoter

    U6 and EF1a

    Available since

    Oct. 29, 2024

    Availability

    Academic Institutions and Nonprofits only

    

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18. px552-sg-gria1-HT

    Plasmid

    #187652

    Purpose

    Contains HaloTag to be inserted into the NTD of Gria1 (via HITI), single guide RNA to target Cas9 to Gria1 under control of the U6 promoter, and miRFP670 under control of human synapsin promoter.

    Depositor

    Erin O'Shea

    Article

    Wong et al Elife. 2024 Aug 15;13:e80622. doi: 10.75

    Inserts

    HaloTag donor sequence
    miRFP670
    

    Use

    AAV and CRISPR

    Tags

    N/A

    Expression

    Mammalian

    Mutation

    Promoter

    Synapsin

    Available since

    Oct. 23, 2024

    Availability

    Academic Institutions and Nonprofits only

    

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19. gRNA_SOX2_HDR

    Plasmid

    #163752

    Purpose

    gRNA expression vector to target the SOX2 stop codon for HDR gene tagging in human cells.

    Depositor

    Jennifer Mitchell

    Article

    Abatti et al Nucleic Acids Res. 2023 Sep 22:gkad734.

    Insert

    gRNA_SOX2 (SOX2 Human)
    

    Use

    CRISPR

    Tags

    Expression

    Mammalian

    Mutation

    Promoter

    U6

    Available since

    Oct. 3, 2024

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

20. pSpCas9-2A-Puro-RAB7A-gRNA2 (PX459)

    Plasmid

    #221552

    Purpose

    Expresses Cas9 and gRNA for disruption of Rab7A gene in human cells

    Depositor

    Shawn Ferguson

    Article

    Talaia et al bioRxiv [Preprint]. 2023 Dec 17:2023.12.

    Insert

    gRNA targeting human Rab7A (RAB7A Human)
    

    Use

    Tags

    Expression

    Mammalian

    Mutation

    Promoter

    U6

    Available since

    July 15, 2024

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge