We narrowed to 6,765 results for: /1000

1. pIGAhRC

   Plasmid

   #112510

   Purpose

   human Ah receptor and Arnt cDNAs expressed under control of Gal1,10 bidirectional promoter

   Depositor

   Charles Miller

   Article

   Miller CA et al Toxicol Appl Pharmacol. 1999 Nov 1;160(3

   Insert

   HIF1B, AhR (ARNT, AHR Budding Yeast, Human)
   

   Use

   Synthetic Biology

   Tags

   Expression

   Yeast

   Mutation

   Promoter

   Gal1,10

   Available since

   July 13, 2018

   Availability

   Academic Institutions and Nonprofits only

   

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2. pPB-tetpA(hBCL2-miR9/9*-124)-iRPT

   Plasmid

   #154881

   Purpose

   Doxycycline-dependently expresses human BCL2 and murine miR9/9*-124. Ubiquitously expresses iRFP713, Puromycin resistance gene, and rtTAM2.

   Depositor

   Hideyuki Okano

   Article

   Nemoto et al Cells. 2020 Dec 22;10(1). pii: cells1001

   Inserts

   iRFP713
   Puromycin resistance gene
   rtTAM2
   BCL2 (BCL2 Human)
   miR9/9*-124
   

   Use

   Tags

   Expression

   Mammalian

   Mutation

   Promoter

   Available since

   Jan. 5, 2021

   Availability

   Academic Institutions and Nonprofits only

   

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3. LV-AR-C563A-C596A

   Plasmid

   #171220

   Purpose

   Lenti-viral expression of human androgen receptor DNA-binding mutant: mutations of one essential cysteine on each of the two zinc fingers.

   Depositor

   Steven Balk

   Article

   Guo et al Nat Commun. 2021 Dec 15;12(1):7308. doi:

   Insert

   AR-C563A-C596A (AR Human)
   

   Use

   Lentiviral

   Tags

   Flag

   Expression

   Mammalian

   Mutation

   AR-C563A-C596A

   Promoter

   EF-1a

   Available since

   Sept. 14, 2021

   Availability

   Academic Institutions and Nonprofits only

   

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4. LV-AR-R599A-N600A

   Plasmid

   #171221

   Purpose

   Lenti-viral expression of human androgen receptor DNA-binding mutant: R599A-N600A, mutations in the D-box of the Zinc finger 2 that mediates AR dimerization.

   Depositor

   Steven Balk

   Article

   Guo et al Nat Commun. 2021 Dec 15;12(1):7308. doi:

   Insert

   AR-R599A-N600A (AR Human)
   

   Use

   Lentiviral

   Tags

   Flag

   Expression

   Mammalian

   Mutation

   AR-R599A-N600A

   Promoter

   EF-1a

   Available since

   Sept. 14, 2021

   Availability

   Academic Institutions and Nonprofits only

   

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5. LV-AR-AAFF

   Plasmid

   #171218

   Purpose

   Lenti-viral expression of human androgen receptor DNA-binding mutant: K580A-V581A, mutations in the P-box of the zinc finger 1 at the KVFF motif.

   Depositor

   Steven Balk

   Article

   Guo et al Nat Commun. 2021 Dec 15;12(1):7308. doi:

   Insert

   AR-AAFF (AR Human)
   

   Use

   Lentiviral

   Tags

   Flag

   Expression

   Mammalian

   Mutation

   AR-K580A-V581A

   Promoter

   EF-1a

   Available since

   Sept. 14, 2021

   Availability

   Academic Institutions and Nonprofits only

   

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6. EIF2AK2 gRNA (BRDN0001148577)

   Plasmid

   #75638

   Purpose

   3rd generation lentiviral gRNA plasmid targeting human EIF2AK2

   Depositor

   David Root, John Doench

   Article

   Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

   Insert

   EIF2AK2 (EIF2AK2 Human)
   

   Use

   CRISPR and Lentiviral

   Tags

   Expression

   Mammalian

   Mutation

   Promoter

   hU6

   Available since

   July 6, 2016

   Availability

   Academic Institutions and Nonprofits only

   

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7. EIF2AK2 gRNA (BRDN0001146342)

   Plasmid

   #75637

   Purpose

   3rd generation lentiviral gRNA plasmid targeting human EIF2AK2

   Depositor

   David Root, John Doench

   Article

   Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

   Insert

   EIF2AK2 (EIF2AK2 Human)
   

   Use

   CRISPR and Lentiviral

   Tags

   Expression

   Mammalian

   Mutation

   Promoter

   hU6

   Available since

   July 6, 2016

   Availability

   Academic Institutions and Nonprofits only

   

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8. EIF2AK2 gRNA (BRDN0001148668)

   Plasmid

   #75639

   Purpose

   3rd generation lentiviral gRNA plasmid targeting human EIF2AK2

   Depositor

   David Root, John Doench

   Article

   Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

   Insert

   EIF2AK2 (EIF2AK2 Human)
   

   Use

   CRISPR and Lentiviral

   Tags

   Expression

   Mammalian

   Mutation

   Promoter

   hU6

   Available since

   July 6, 2016

   Availability

   Academic Institutions and Nonprofits only

   

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9. TFORF2553

   Plasmid

   #142958

   Purpose

   Lentiviral vector for overexpressing transcription factor ORFs with unique 24-bp barcodes. Barcodes facilitate identification of transcription factors in pooled screens.

   Depositor

   Feng Zhang

   Article

   Joung et al Cell. 2023 Jan 5;186(1):209-229.e26. doi

   Insert

   AR (AR Human)
   

   Use

   Lentiviral

   Tags

   Expression

   Mammalian

   Mutation

   Promoter

   EF1a

   Available since

   June 20, 2023

   Availability

   Academic Institutions and Nonprofits only

   

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10. CDK6 gRNA (BRDN0001145692)

    Plasmid

    #75643

    Purpose

    3rd generation lentiviral gRNA plasmid targeting human CDK6

    Depositor

    David Root, John Doench

    Article

    Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

    Insert

    CDK6 (CDK6 Human)
    

    Use

    CRISPR and Lentiviral

    Tags

    Expression

    Mammalian

    Mutation

    Promoter

    hU6

    Available since

    July 6, 2016

    Availability

    Academic Institutions and Nonprofits only

    

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11. pCMV-hAR-R617M,K618M,K632M,K633M

    Plasmid

    #115778

    Purpose

    Expresses human androgen receptor (R617M, K618M, K632M, K633M) in mammalian cells

    Depositor

    Elizabeth Wilson

    Article

    Zhou et al J Biol Chem. 1994 May 6;269(18):13115-23

    Insert

    Androgen Receptor (AR Human)
    

    Use

    Tags

    Expression

    Mammalian

    Mutation

    R617M, K618M ,K632M, K633M, insertion of Q81 and …

    Promoter

    CMV

    Available since

    Oct. 15, 2018

    Availability

    Academic Institutions and Nonprofits only

    

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12. CDK6 gRNA (BRDN0001146904)

    Plasmid

    #75644

    Purpose

    3rd generation lentiviral gRNA plasmid targeting human CDK6

    Depositor

    David Root, John Doench

    Article

    Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

    Insert

    CDK6 (CDK6 Human)
    

    Use

    CRISPR and Lentiviral

    Tags

    Expression

    Mammalian

    Mutation

    Promoter

    hU6

    Available since

    July 6, 2016

    Availability

    Academic Institutions and Nonprofits only

    

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13. pBiex1-SYNAC

    Plasmid

    #82710

    Purpose

    Synthetic soluble adenylyl cyclase FRET sensor and cAMP generator

    Depositor

    Sivaraj Sivaramakrishnan

    Article

    Ritt et al Mol Pharmacol. 2016 Apr;89(4):407-12. do

    Insert

    SYNAC (ADCY2, ADCY5 Human)
    

    Use

    Tags

    FLAG, mCerulean, and mCitrine

    Expression

    Bacterial and Insect

    Mutation

    Promoter

    T7

    Available since

    Nov. 3, 2016

    Availability

    Academic Institutions and Nonprofits only

    

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14. Flag-M4-AR-W741C-S650A

    Plasmid

    #171252

    Purpose

    Mammalian expression of 3xFlag-tagged human androgen receptor phosphorylation mutant that binds to bicalutamide: AR-Trp741Cys-Ser650Ala (AR-W741C-S650A)

    Depositor

    Steven Balk

    Article

    Liu et al Oncotarget. 2016 Jan 12;7(2):1754-64. do

    Insert

    3xFlag-tagged human androgen receptor Trp741Cys-Ser650Ala mutant (AR Human)
    

    Use

    Tags

    Flag

    Expression

    Mammalian

    Mutation

    AR-Trp741Cys-Ser650Ala (AR-W741C-S650A)

    Promoter

    CMV

    Available since

    June 25, 2021

    Availability

    Academic Institutions and Nonprofits only

    

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15. Flag-M4-AR-W741C-S650D

    Plasmid

    #171253

    Purpose

    Mammalian expression of 3xFlag-tagged human androgen receptor phosphorylation mutant that binds to bicalutamide: AR-Trp741Cys-Ser650Asp (AR-W741C-S650D)

    Depositor

    Steven Balk

    Article

    Liu et al Oncotarget. 2016 Jan 12;7(2):1754-64. do

    Insert

    3xFlag-tagged human androgen receptor Trp741Cys-Ser650Asp mutant (AR Human)
    

    Use

    Tags

    Flag

    Expression

    Mammalian

    Mutation

    AR-Trp741Cys-Ser650Asp (AR-W741C-S650D)

    Promoter

    CMV

    Available since

    June 24, 2021

    Availability

    Academic Institutions and Nonprofits only

    

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16. CDK6 gRNA (BRDN0001147855)

    Plasmid

    #75645

    Purpose

    3rd generation lentiviral gRNA plasmid targeting human CDK6

    Depositor

    David Root, John Doench

    Article

    Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

    Insert

    CDK6 (CDK6 Human)
    

    Use

    CRISPR and Lentiviral

    Tags

    Expression

    Mammalian

    Mutation

    Promoter

    hU6

    Available since

    July 6, 2016

    Availability

    Academic Institutions and Nonprofits only

    

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17. mKO2-CDK6

    Plasmid

    #215066

    Purpose

    Expresses mKO2-CDK6 in mammalian cells from a retroviral vector.

    Depositor

    Michele Pagano

    Article

    Rona et al Mol Cell. 2024 Feb 29:S1097-2765(24)0012

    Insert

    CDK6 (CDK6 Human)
    

    Use

    Retroviral

    Tags

    mKO2

    Expression

    Mammalian

    Mutation

    Promoter

    LTR

    Available since

    April 8, 2024

    Availability

    Academic Institutions and Nonprofits only

    

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18. pKLV2-U6gRNA5(CDK6-E1(6))-PGKpuro2ABFP-W

    Plasmid

    #200487

    Purpose

    Lentiviral vector expressing gRNA targeting human CDK6-E1

    Depositor

    Kosuke Yusa

    Article

    Aoki et al Blood. 2023 Nov 3:blood.2023020857. doi:

    Insert

    CDK6-E1(6) (CDK6 Human)
    

    Use

    Lentiviral

    Tags

    Expression

    Mutation

    Promoter

    Available since

    April 1, 2024

    Availability

    Academic Institutions and Nonprofits only

    

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19. pKLV2-U6gRNA5(CDK6-E2(12))-PGKpuro2ABFP-W

    Plasmid

    #200488

    Purpose

    Lentiviral vector expressing gRNA targeting human CDK6-E2

    Depositor

    Kosuke Yusa

    Article

    Aoki et al Blood. 2023 Nov 3:blood.2023020857. doi:

    Insert

    CDK6-E2(12) (CDK6 Human)
    

    Use

    Lentiviral

    Tags

    Expression

    Mutation

    Promoter

    Available since

    Jan. 9, 2024

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

20. pKLV2-U6gRNA5(CDK6-E1(1))-PGKpuro2ABFP-W

    Plasmid

    #200486

    Purpose

    Lentiviral vector expressing gRNA targeting human CDK6-E1

    Depositor

    Kosuke Yusa

    Article

    Aoki et al Blood. 2023 Nov 3:blood.2023020857. doi:

    Insert

    CDK6-E1(1) (CDK6 Human)
    

    Use

    Lentiviral

    Tags

    Expression

    Mutation

    Promoter

    Available since

    Jan. 9, 2024

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge