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Plasmid#200660PurposeConstruct for chemogenetically silencing and visualizing subpopulations of neurons in the retinaDepositorInsertDREADD Gi-mCherry
UseAAV, Cre/Lox, and Mouse Targeting ; IntrsectTagsmCherryExpressionMammalianMutationPromoterhSynAvailable sinceNov. 13, 2024AvailabilityAcademic Institutions and Nonprofits only -
pOttc438 - pAAV EF1a CRE ERT2 bGHpA
Plasmid#210415PurposeAAV viral vector packaging plasmid that expresses tamoxifen-regulated Cre recombinaseDepositorInsertCre-ERT2
UseAAVTagsExpressionMutationPromoterEF1aAvailable sinceJan. 2, 2024AvailabilityAcademic Institutions and Nonprofits only -
pLVTH
Plasmid#12262DepositorTypeEmpty backboneUseCre/Lox, Lentiviral, and RNAiTagsExpressionMammalianMutationPromoterAvailable sinceAug. 4, 2006AvailabilityAcademic Institutions and Nonprofits only -
p223-RV-dlx-dio-Tdtomato-T2A-SYPEGFP
Plasmid#185699PurposeRetroviral vector expression cre-dependent Tdtomato-T2A-SynaptophysinEGFP driven by the mDlx promoterDepositorInsertsTdtomato,
Synaptophysin-EGFP
UseCre/Lox and RetroviralTagsEGFP and T2AExpressionMammalianMutationPromotermDlxAvailable sinceJuly 8, 2022AvailabilityAcademic Institutions and Nonprofits only -
pLP-mOlig2-ires-gfp
Plasmid#49399Purposemammalian bicistronic expression of mouse Olig2 and EGFPDepositorInsertOlig2 (Olig2 Mouse)
UseCre/Lox; Acceptor vectorTagsEGFP and IRESExpressionMammalianMutationPromoterCMVAvailable sinceApril 23, 2014AvailabilityAcademic Institutions and Nonprofits only -
AAV-DIO-TC66T-2A-oG
Plasmid#178430PurposeExpresses TVA(TC66T) and optimized Rabies G (oG) protein in a FLEX cassetteDepositorInsertsTVA950 Glu66→Thr
Optimized G
UseAAV and Cre/Lox; Adeno-associated virusTagsExpressionMutationPromoterhSynAvailable sinceFeb. 17, 2022AvailabilityAcademic Institutions and Nonprofits only -
pAAV-FLEX-C-RG
Plasmid#49101PurposeCre dependent Cerulean-E2A-SADB19 rabies glycoprotein expression, under EF1a promoter, in AAV virusDepositorInsertCerulean-E2A-RG
UseAAV and Cre/LoxTagsceruleanExpressionMammalianMutationPromoterEF1aAvailable sinceMarch 2, 2015AvailabilityAcademic Institutions and Nonprofits only -
AiP2141 - pAAV-AiE2333m-minBG-iCre(R297T)-BGHpA
Plasmid#220731PurposeAiE2333m is an enhancer sequence, designed to induce cre-dependent recombination in specific populations of brain cellsInsertiCre(R297T)
UseAAVTagsExpressionMutationPromoterminBGAvailable sinceMay 7, 2025AvailabilityAcademic Institutions and Nonprofits only -
pRDA_852
Plasmid#185527PurposeLentiviral vector that enables Cre-mediated expression of two sgRNAs. Also encodes the fluorophore violet-excited GFP (Vex) as a marker of transduction.DepositorInsertsFirst sgRNA cassette
Second sgRNA cassette
UseCRISPR, Cre/Lox, and Lentiviral ; Flp/frtTagsExpressionMammalianMutationPromoterHuman U6 and Mouse U6Available sinceApril 1, 2025AvailabilityAcademic Institutions and Nonprofits only -
AiP2068 - pAAV-AiE2587m-minBG-iCre(R297T)-BGHpA
Plasmid#220728PurposeAiE2587m is an enhancer sequence, designed to induce cre-dependent recombination in specific populations of brain cellsInsertiCre(R297T)
UseAAVTagsExpressionMutationPromoterminBGAvailable sinceMarch 13, 2025AvailabilityAcademic Institutions and Nonprofits only -
AiP2047 - pAAV-AiE2538m-minBG-iCre(R297T)-BGHpA
Plasmid#220726PurposeAiE2538m is an enhancer sequence, designed to induce cre-dependent recombination in specific populations of brain cellsInsertiCre(R297T)
UseAAVTagsExpressionMutationPromoterminBGAvailable sinceMarch 13, 2025AvailabilityAcademic Institutions and Nonprofits only -
AiP20025 - pAAV-AiE2564m-minBG-iCre(R297T)-BGHpA
Plasmid#220733PurposeAiE2564m is an enhancer sequence, designed to induce cre-dependent recombination in specific populations of brain cellsInsertiCre(R297T)
UseAAVTagsExpressionMutationPromoterminBGAvailable sinceMarch 7, 2025AvailabilityAcademic Institutions and Nonprofits only -
AiP20024 - pAAV-AiE2531m-minBG-iCre(R297T)-BGHpA
Plasmid#220732PurposeAiE2531m is an enhancer sequence, designed to induce cre-dependent recombination in specific populations of brain cellsInsertiCre(R297T)
UseAAVTagsExpressionMutationPromoterminBGAvailable sinceFeb. 25, 2025AvailabilityAcademic Institutions and Nonprofits only -
AiP2136 - pAAV-AiE2586m-minBG-iCre(R297T)-BGHpA
Plasmid#220729PurposeAiE2586m is an enhancer sequence, designed to induce cre-dependent recombination in specific populations of brain cellsInsertiCre(R297T)
UseAAVTagsExpressionMutationPromoterminBGAvailable sinceFeb. 25, 2025AvailabilityAcademic Institutions and Nonprofits only -
AiP20068 - pAAV-AiE2366m-minBG-iCre(R297T)-BGHpA
Plasmid#220737PurposeAiE2366m is an enhancer sequence, designed to induce cre-dependent recombination in specific populations of brain cellsInsertiCre(R297T)
UseAAVTagsExpressionMutationPromoterminBGAvailable sinceFeb. 25, 2025AvailabilityAcademic Institutions and Nonprofits only -
AiP20028 - pAAV-AiE0732h-minBG-iCre(R297T)-BGHpA
Plasmid#220736PurposeAiE0732h is an enhancer sequence, designed to induce cre-dependent recombination in specific populations of brain cellsInsertiCre(R297T)
UseAAVTagsExpressionMutationPromoterminBGAvailable sinceFeb. 25, 2025AvailabilityAcademic Institutions and Nonprofits only -
AiP20026 - pAAV-AiE0671m_3xC2-minBG-iCre(R297T)-BGHpA
Plasmid#220734PurposeAiE0671m_3xC2 is an optimized enhancer sequence, designed to induce cre-dependent recombination in specific populations of brain cellsInsertiCre(R297T)
UseAAVTagsExpressionMutationPromoterminBGAvailable sinceFeb. 25, 2025AvailabilityAcademic Institutions and Nonprofits only -
pOttc556 - pAAV EF1a iCre
Plasmid#210416PurposeAAV viral vector packaging plasmid that expresses "improved Cre recombinase"DepositorInsertiCre
UseAAVTagsExpressionMutationPromoterEF1aAvailable sinceJan. 2, 2024AvailabilityAcademic Institutions and Nonprofits only -
pB6-Rosa26-cre_dre_reporter_1_2
Plasmid#185966PurposeB6J Rosa26-cre dre reporter 1.2 allele targeting vector, low copy numberDepositorInsertsfGFP, tdTomato
UseCre/Lox and Mouse Targeting; Dre/roxTagsExpressionMammalianMutationPromoterAvailable sinceJuly 20, 2022AvailabilityAcademic Institutions and Nonprofits only -
pB6-Rosa26-cre_dre_reporter_1_1b
Plasmid#185965PurposeB6J Rosa26-cre dre reporter 1.1b allele targeting vector, low copy numberDepositorInsertsfGFP, tdTomato
UseCre/Lox and Mouse Targeting; Dre/roxTagsExpressionMammalianMutationPromoterAvailable sinceJuly 20, 2022AvailabilityAcademic Institutions and Nonprofits only -
pB6-Rosa26-cre_dre_reporter_1_1a
Plasmid#185964PurposeB6J Rosa26-cre dre reporter 1.1a allele targeting vector, low copy numberDepositorInsertsfGFP, tdTomato
UseCre/Lox and Mouse Targeting; Dre/roxTagsExpressionMammalianMutationPromoterAvailable sinceJuly 20, 2022AvailabilityAcademic Institutions and Nonprofits only -
pB6-Rosa26-cre_dre_reporter_1_1
Plasmid#185963PurposeB6J Rosa26-cre dre reporter 1.1 allele targeting vector, low copy numberDepositorInsertEGFP, tdTomato
UseCre/Lox and Mouse Targeting; Dre/roxTagsExpressionMammalianMutationPromoterAvailable sinceJuly 20, 2022AvailabilityAcademic Institutions and Nonprofits only -
pBSIIKS_HIS3_I
Plasmid#109062Purposeyeast shuttle vector with deletable CEN6-ARSH4 cassette in pBIIKS backbone. LoxP site upstream of HIS3. For teaching purposes.DepositorInsertHIS3 (HIS3 Budding Yeast, Zygosaccharomyces rouxii)
UseCre/LoxTagsExpressionBacterial and YeastMutationPromoterHIS3Available sinceAug. 1, 2018AvailabilityAcademic Institutions and Nonprofits only -
AAV:ITR-U6-sgRNA(backbone)-pCBh-Cre-WPRE-hGHpA-ITR
Plasmid#60229PurposeExpresses Cre recombinase from the Cbh promoter and one U6-driven sgRNA. AAV backbone with SapI spacer for sgRNA cloning.DepositorInsertssgRNA
Cre recombinase
UseAAV, CRISPR, Cre/Lox, and Mouse TargetingTagsCre-HAExpressionMammalianMutationPromoterCBh and U6Available sinceOct. 9, 2014AvailabilityAcademic Institutions and Nonprofits only -
DRH002_scAAV-hSyn-delta_iCre-HA
Plasmid#225087PurposeExpression of inactive delta-iCre (control) with an HA tag in neurons driven by human synapsin promoter.DepositorInsertdelta_iCre
UseAAV and Cre/LoxTagsHAExpressionMammalianMutationPromoterhSynAvailable sinceOct. 21, 2024AvailabilityAcademic Institutions and Nonprofits only -
pF CAG luc-EGFP-cre puro
Plasmid#67503PurposeConstitutive expression of a firefly luciferase-enhanced green fluorescent protein-cre recombinase fusion protein in mammalian cellsDepositorInsertluciferase-EGFP-cre
UseCre/Lox, Lentiviral, and Luciferase ; Fluorescent…TagsExpressionMammalianMutationPromoterCAGAvailable sinceFeb. 17, 2017AvailabilityAcademic Institutions and Nonprofits only -
pAAV-hsyn-flex-Voltron-ST
Plasmid#119036PurposeCre-dependant expression of soma-localized Voltron in neuronsDepositorHas ServiceAAV1InsertVoltron-ST
UseAAV and Cre/LoxTagsExpressionMammalianMutationPromoterhsynAvailable sinceDec. 19, 2018AvailabilityAcademic Institutions and Nonprofits only -
Rasgrf2-2A-dCre targeting vector
Plasmid#61573PurposeTarget a DHFR-destabilized Cre recombinase gene to the stop codon of the mouse Rasgrf2 geneDepositorInsertRasgrf2-2A-dCre (Rasgrf2 P1 bacteriophage, Mouse)
UseCre/Lox and Mouse TargetingTagsExpressionMutationPromoterAvailable sinceMarch 31, 2015AvailabilityAcademic Institutions and Nonprofits only -
pHAGE2-EF1aL-Cre-IRES-NeoR-W
Plasmid#126700Purposelentiviral or plasmid based co-expression of Cre recombinase and a neomycin resistance cassetteDepositorInsertCre-IRES
UseCre/Lox and LentiviralTagsSV40 NLSExpressionMutationPromoterEf1aAvailable sinceJuly 9, 2020AvailabilityAcademic Institutions and Nonprofits only -
HS_NAM-B1
Plasmid#154064PurposeLevel M, P1 Golden Gate vector. OsAct::Hyg-nosT/HvHSP17::Cre-hspT/ZmUbi::loxP-GUS-loxP-NAM-B1-nosTDepositorInsertsHygromycin phosphotransferase
Cre recombinase
LoxP-flanked GUS and TtNAM-B1
UseCre/Lox and Synthetic Biology; Golden gateTagsExpressionBacterial and PlantMutationThe TtNAM-B1 gene sequence was domesticated to re…PromoterHvHSP17, OsAct, and ZmUbiAvailable sinceSept. 30, 2020AvailabilityAcademic Institutions and Nonprofits only -
Slc17a7-IRES2-Cre targeting vector
Plasmid#61574PurposeTarget the Cre recombinase gene to the stop codon of the mouse Slc17a7 (VGlut1) geneDepositorInsertSlc17a7-IRES2-Cre
UseCre/Lox and Mouse TargetingTagsExpressionMutationPromoterAvailable sinceJuly 30, 2015AvailabilityAcademic Institutions and Nonprofits only -
Pvalb-2A-Cre targeting vector
Plasmid#61570PurposeTarget the Cre recombinase gene to the stop codon of the mouse Pvalb geneDepositorInsertPvalb exon 4 - 2A - Cre
UseCre/Lox and Mouse TargetingTagsExpressionMutationPromoterAvailable sinceMarch 18, 2015AvailabilityAcademic Institutions and Nonprofits only -
DRH001_scAAV-hSyn-iCre-HA
Plasmid#225086PurposeExpression of iCre with an HA tag in neurons driven by human synapsin promoter.DepositorInsertiCre
UseAAV and Cre/LoxTagsHAExpressionMammalianMutationPromoterhSynAvailable sinceOct. 21, 2024AvailabilityAcademic Institutions and Nonprofits only -
TDP-REGv2 Triple Cryptic Cre recombinase in pTwist-CMV
Plasmid#216162PurposeExpresses Cre recombinase in cells lacking TDP-43 function. Note: It is not recommended to produce lentiviruses containing TDP-REG sequences – see Depositor CommentsDepositorInsertCre recombinase with N-terminal SV40 NLS and C-terminal c-Myc NLS
UseCre/LoxTagsExpressionMammalianMutationPromoterAvailable sinceJuly 1, 2024AvailabilityAcademic Institutions and Nonprofits only -
pAAV-nEF-Con/Fon DREADD Gi-mCherry
Plasmid#177672PurposeExpresses DREADD hM4D (Gi) in Cre and Flp expressing cellsDepositorHas ServiceAAV8InsertDREADD Gi-mCherry
UseAAV, Cre/Lox, and Mouse Targeting ; IntrsectTagsmCherryExpressionMammalianMutationPromoternEFAvailable sinceNov. 23, 2021AvailabilityAcademic Institutions and Nonprofits only -
AiP13450: pAAV-AiE0140h-minBG-iCre-4X2C-WPRE3-BGHpA (Alias: CN3450)
Plasmid#214845PurposeExpression of iCre in striatal Pvalb neuronsInsertiCre
UseAAVTagsExpressionMutationPromoterAvailable sinceJuly 15, 2024AvailabilityAcademic Institutions and Nonprofits only -
PGKneoF2L2DTA
Plasmid#13445DepositorInsertPGKneoF2L2DTA
UseCre/LoxTagsExpressionMammalianMutationPromoterAvailable sinceNov. 16, 2006AvailabilityAcademic Institutions and Nonprofits only -
pINS-Blast
Plasmid#31388DepositorInsertbsd
UseCre/LoxTagsExpressionMutationPromoterAvailable sinceSept. 13, 2012AvailabilityAcademic Institutions and Nonprofits only -
pCAG-EGFP/RFP-int
Plasmid#19818DepositorTypeEmpty backboneUseCre/Lox and RNAiTagsExpressionMammalianMutationPromoterAvailable sinceNov. 21, 2008AvailabilityAcademic Institutions and Nonprofits only -
pINS-Neo
Plasmid#31390DepositorInsertaph
UseCre/LoxTagsExpressionMutationPromoterAvailable sinceApril 10, 2012AvailabilityAcademic Institutions and Nonprofits only