14,515 results

1. CSF1R gRNA (BRDN0001146892)

   Plasmid

   #77039

   Purpose

   3rd generation lentiviral gRNA plasmid targeting human CSF1R

   Depositor

   John Doench, David Root

   Article

   Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

   Insert

   CSF1R (CSF1R Human)
   

   Use

   CRISPR and Lentiviral

   Tags

   Expression

   Mammalian

   Mutation

   Promoter

   hU6

   Available since

   July 6, 2016

   Availability

   Academic Institutions and Nonprofits only

   

   Enlarge

2. pCfB3037(XI-5 MarkerFree)

   Plasmid

   #73277

   Purpose

   EasyClone-MarkerFree backbone vector for the addition of 1 or 2 genes and promoters for integration into site XI-5 (Chr XI: 11779..118967)

   Depositor

   Irina Borodina

   Article

   Jessop-Fabre et al Biotechnol J. 2016 Aug;11(8):1110-7. doi

   Type

   Empty backbone

   Use

   CRISPR and Synthetic Biology

   Tags

   Expression

   Yeast

   Mutation

   Promoter

   Available since

   Nov. 23, 2016

   Availability

   Academic Institutions and Nonprofits only

   

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3. IRAK1 gRNA (BRDN0001147615)

   Plasmid

   #76419

   Purpose

   3rd generation lentiviral gRNA plasmid targeting human IRAK1

   Depositor

   John Doench, David Root

   Article

   Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

   Insert

   IRAK1 (IRAK1 Human)
   

   Use

   CRISPR and Lentiviral

   Tags

   Expression

   Mammalian

   Mutation

   Promoter

   hU6

   Available since

   July 6, 2016

   Availability

   Academic Institutions and Nonprofits only

   

   Enlarge

4. IRAK3 gRNA (BRDN0001146930)

   Plasmid

   #77714

   Purpose

   3rd generation lentiviral gRNA plasmid targeting human IRAK3

   Depositor

   John Doench, David Root

   Article

   Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

   Insert

   IRAK3 (IRAK3 Human)
   

   Use

   CRISPR and Lentiviral

   Tags

   Expression

   Mammalian

   Mutation

   Promoter

   hU6

   Available since

   July 6, 2016

   Availability

   Academic Institutions and Nonprofits only

   

   Enlarge

5. IRAK3 gRNA (BRDN0001146977)

   Plasmid

   #77715

   Purpose

   3rd generation lentiviral gRNA plasmid targeting human IRAK3

   Depositor

   John Doench, David Root

   Article

   Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

   Insert

   IRAK3 (IRAK3 Human)
   

   Use

   CRISPR and Lentiviral

   Tags

   Expression

   Mammalian

   Mutation

   Promoter

   hU6

   Available since

   July 6, 2016

   Availability

   Academic Institutions and Nonprofits only

   

   Enlarge

6. PM-TD!TA

   Plasmid

   #48655

   Purpose

   Bacterial TD crRNA expression: targets TD to protospacer A (TACCATCTCAAGCTTGTTGA), p15A/chloramphenicol

   Depositor

   George Church

   Article

   Esvelt et al Nat Methods. 2013 Sep 29. doi: 10.1038/n

   Insert

   Bacterial TD crRNA to prototspacer A
   

   Use

   CRISPR

   Tags

   Expression

   Mutation

   Promoter

   J23100 promoter

   Available since

   Oct. 17, 2013

   Availability

   Academic Institutions and Nonprofits only

   

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7. pX330A_FokI-1x3

   Plasmid

   #63603

   Purpose

   Expresses FokI-dCas9 and gRNA

   Depositor

   Takashi Yamamoto

   Article

   Nakagawa et al BMC Biotechnol. 2015 May 22;15(1):33.

   Insert

   FokI-dCas9
   

   Use

   CRISPR

   Tags

   Expression

   Mammalian

   Mutation

   Promoter

   CBh

   Available since

   June 1, 2015

   Availability

   Academic Institutions and Nonprofits only

   

   Enlarge

8. PLAU gRNA (BRDN0001147652)

   Plasmid

   #77102

   Purpose

   3rd generation lentiviral gRNA plasmid targeting human PLAU

   Depositor

   John Doench, David Root

   Article

   Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

   Insert

   PLAU (PLAU Human)
   

   Use

   CRISPR and Lentiviral

   Tags

   Expression

   Mammalian

   Mutation

   Promoter

   hU6

   Available since

   July 6, 2016

   Availability

   Academic Institutions and Nonprofits only

   

   Enlarge

9. pYPQ255-x3.7

   Plasmid

   #124311

   Purpose

   Gateway entry vector with rAPOBEC1 and pcoCas9D10A-x3.7 for C-T base editing

   Depositor

   Yiping Qi

   Article

   Zhong et al Mol Plant. 2019 Mar 27. pii: S1674-2052(

   Insert

   rAPOBEC1-pcoCas9D10A_x3.7-UGI
   

   Use

   CRISPR

   Tags

   Expression

   Mutation

   Promoter

   Available since

   May 22, 2019

   Availability

   Academic Institutions and Nonprofits only

   

   Enlarge

10. pYPQ256-x3.7

    Plasmid

    #124313

    Purpose

    Gateway entry vector with PmCDA1 and pcoCas9D10A-x3.7 for C-T base editing

    Depositor

    Yiping Qi

    Article

    Zhong et al Mol Plant. 2019 Mar 27. pii: S1674-2052(

    Insert

    pcoCas9D10A_x3.7-PmCDA1-UGI
    

    Use

    CRISPR

    Tags

    Expression

    Mutation

    Promoter

    Available since

    May 22, 2019

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

11. pRB1084

    Plasmid

    #71516

    Purpose

    Expresses gRNA for dpy-10 conversion using NGCG PAM and VRER Cas9 mutant

    Depositor

    Andrew Fire

    Article

    Bell et al Genetics. 2015 Dec 17. pii: genetics.115

    Insert

    dpy-10 gRNA
    

    Use

    CRISPR

    Tags

    Expression

    Worm

    Mutation

    Promoter

    U6

    Available since

    Dec. 10, 2015

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

12. pEPOR0SP0021

    Plasmid

    #117532

    Purpose

    Level0 Golden Gate part: CDS, SaCas9 (no stop codon)

    Depositor

    Nicola Patron

    Article

    Raitskin et al PLoS One. 2019 Feb 27;14(2):e0211598. do

    Insert

    SaCas9 (no stop codon)
    

    Use

    CRISPR

    Tags

    Expression

    Mutation

    Promoter

    Available since

    April 2, 2019

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

13. pZNF416.1.0-gDNA

    Plasmid

    #112468

    Purpose

    CRISPR plasmid for expression of Cas9 and gRNA targeting human transcription factor ZNF416

    Depositor

    Kevin White

    Insert

    ZNF416 (ZNF416 Human)
    

    Use

    CRISPR

    Tags

    Expression

    Mammalian

    Mutation

    Promoter

    Available since

    Dec. 10, 2018

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

14. pZNF416-donor

    Plasmid

    #112372

    Purpose

    CRISPR donor plasmid to tag human transcription factor ZNF416 with GFP

    Depositor

    Kevin White

    Insert

    ZNF416 homology arms flanking EGFP-IRES-Neo cassette (ZNF416 Human)
    

    Use

    CRISPR

    Tags

    Expression

    Mutation

    hg38:19:57572882:A>G,hg38:19:57572932:C>G,h…

    Promoter

    Available since

    Dec. 3, 2018

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

15. p426_Cas9_gRNA-ARS720a

    Plasmid

    #87392

    Purpose

    All-in-one CRISPR plasmid for integrating, deleting, or replacing a gene in S. cerevisiae. High-copy, URA3 plasmid contains human codon-optimized Cas9 and a guide RNA targeting ARS720a sequence CAACAATTGTTACAATAGTA in yeast chromosome 7.

    Depositor

    Aindrila Mukhopadhyay

    Article

    Reider Apel et al Nucleic Acids Res. 2017 Jan 9;45(1):496-

    Insert

    Human Optimized S. pyogenes Cas9 and guide RNA targeting ARS720a
    

    Use

    CRISPR

    Tags

    Expression

    Mutation

    Promoter

    ADH1, pTyrosine

    Available since

    April 5, 2017

    Availability

    Academic Institutions and Nonprofits only

    

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16. sgRNA3_NANOG

    Plasmid

    #64155

    Purpose

    Photoactivatable transcription system. Lentiviral expression of NANOG sgRNA3. Also contains a CMV-puro-t2A-mCherry expression cassette

    Depositor

    Moritoshi Sato

    Article

    Nihongaki et al Chem Biol. 2015 Feb 19;22(2):169-74. doi

    Insert

    sgRNA3_NANOG (NANOG Human)
    

    Use

    CRISPR and Lentiviral

    Tags

    Expression

    Mammalian

    Mutation

    Promoter

    U6

    Available since

    April 15, 2015

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

17. pCD294.9

    Plasmid

    #113319

    Purpose

    dCas9, PCP-SoxS_R93A, J109 scRNA.b1

    Depositor

    Jesse Zalatan

    Article

    Dong et al Nat Commun. 2018 Jun 27;9(1):2489. doi:

    Insert

    dCas9, PCP-SoxS_R93A, J109 scRNA.b1_PP7
    

    Use

    CRISPR

    Tags

    Expression

    Bacterial

    Mutation

    R93A

    Promoter

    Available since

    Aug. 1, 2018

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

18. AURKB A4.4 gRNA

    Plasmid

    #90547

    Purpose

    3rd generation lentiviral gRNA plasmid targeting human AURKB

    Depositor

    Iain Cheeseman

    Article

    McKinley et al Dev Cell. 2017 Feb 27;40(4):405-420.e2.

    Insert

    AURKB (Guide Designation A4.4)
    

    Use

    CRISPR and Lentiviral

    Tags

    Expression

    Mutation

    Promoter

    U6

    Available since

    July 21, 2017

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

19. AURKB A3.4 gRNA

    Plasmid

    #90546

    Purpose

    3rd generation lentiviral gRNA plasmid targeting human AURKB

    Depositor

    Iain Cheeseman

    Article

    McKinley et al Dev Cell. 2017 Feb 27;40(4):405-420.e2.

    Insert

    AURKB (Guide Designation A3.4)
    

    Use

    CRISPR and Lentiviral

    Tags

    Expression

    Mutation

    Promoter

    U6

    Available since

    July 21, 2017

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

20. INCENP G4.3 gRNA

    Plasmid

    #90713

    Purpose

    3rd generation lentiviral gRNA plasmid targeting human INCENP

    Depositor

    Iain Cheeseman

    Article

    McKinley et al Dev Cell. 2017 Feb 27;40(4):405-420.e2.

    Insert

    INCENP (Guide Designation G4.3)
    

    Use

    CRISPR and Lentiviral

    Tags

    Expression

    Mutation

    Promoter

    U6

    Available since

    July 19, 2017

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

21. INCENP G3.3 gRNA

    Plasmid

    #90712

    Purpose

    3rd generation lentiviral gRNA plasmid targeting human INCENP

    Depositor

    Iain Cheeseman

    Article

    McKinley et al Dev Cell. 2017 Feb 27;40(4):405-420.e2.

    Insert

    INCENP (Guide Designation G3.3)
    

    Use

    CRISPR and Lentiviral

    Tags

    Expression

    Mutation

    Promoter

    U6

    Available since

    July 19, 2017

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

22. AURKB A3.1 gRNA

    Plasmid

    #90544

    Purpose

    3rd generation lentiviral gRNA plasmid targeting human AURKB

    Depositor

    Iain Cheeseman

    Article

    McKinley et al Dev Cell. 2017 Feb 27;40(4):405-420.e2.

    Insert

    AURKB (Guide Designation A3.1)
    

    Use

    CRISPR and Lentiviral

    Tags

    Expression

    Mutation

    Promoter

    U6

    Available since

    July 17, 2017

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

23. CDK10 gRNA (BRDN0001145808)

    Plasmid

    #77578

    Purpose

    3rd generation lentiviral gRNA plasmid targeting human CDK10

    Depositor

    John Doench, David Root

    Article

    Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

    Insert

    CDK10 (CDK10 Human)
    

    Use

    CRISPR and Lentiviral

    Tags

    Expression

    Mammalian

    Mutation

    Promoter

    hU6

    Available since

    July 6, 2016

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

24. CDK10 gRNA (BRDN0001149446)

    Plasmid

    #77579

    Purpose

    3rd generation lentiviral gRNA plasmid targeting human CDK10

    Depositor

    John Doench, David Root

    Article

    Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

    Insert

    CDK10 (CDK10 Human)
    

    Use

    CRISPR and Lentiviral

    Tags

    Expression

    Mammalian

    Mutation

    Promoter

    hU6

    Available since

    July 6, 2016

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

25. IRAK1 gRNA (BRDN0001145800)

    Plasmid

    #76418

    Purpose

    3rd generation lentiviral gRNA plasmid targeting human IRAK1

    Depositor

    John Doench, David Root

    Article

    Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

    Insert

    IRAK1 (IRAK1 Human)
    

    Use

    CRISPR and Lentiviral

    Tags

    Expression

    Mammalian

    Mutation

    Promoter

    hU6

    Available since

    July 6, 2016

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

26. pCUX1.1.0-gDNA

    Plasmid

    #112434

    Purpose

    CRISPR plasmid for expression of Cas9 and gRNA targeting human transcription factor CUX1

    Depositor

    Kevin White

    Insert

    CUX1 (CUX1 Human)
    

    Use

    CRISPR

    Tags

    Expression

    Mammalian

    Mutation

    Promoter

    Available since

    Dec. 7, 2018

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

27. LIMK1 gRNA (BRDN0001144875)

    Plasmid

    #76046

    Purpose

    3rd generation lentiviral gRNA plasmid targeting human LIMK1

    Depositor

    John Doench, David Root

    Article

    Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

    Insert

    LIMK1 (LIMK1 Human)
    

    Use

    CRISPR and Lentiviral

    Tags

    Expression

    Mammalian

    Mutation

    Promoter

    hU6

    Available since

    July 6, 2016

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

28. LIMK2 gRNA (BRDN0001148526)

    Plasmid

    #75972

    Purpose

    3rd generation lentiviral gRNA plasmid targeting human LIMK2

    Depositor

    John Doench, David Root

    Article

    Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

    Insert

    LIMK2 (LIMK2 Human)
    

    Use

    CRISPR and Lentiviral

    Tags

    Expression

    Mammalian

    Mutation

    Promoter

    hU6

    Available since

    July 6, 2016

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

29. LIMK2 gRNA (BRDN0001147235)

    Plasmid

    #75973

    Purpose

    3rd generation lentiviral gRNA plasmid targeting human LIMK2

    Depositor

    John Doench, David Root

    Article

    Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

    Insert

    LIMK2 (LIMK2 Human)
    

    Use

    CRISPR and Lentiviral

    Tags

    Expression

    Mammalian

    Mutation

    Promoter

    hU6

    Available since

    July 6, 2016

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

30. TDK promoter dCas9

    Plasmid

    #113657

    Purpose

    dCas9 expression unit plasmid. The dCas9 expression unit plasmids contain connector ConL1, ConRE, and one dCas9 transcriptional unit.

    Depositor

    Jeffrey Barrick

    Article

    Geng et al ACS Synth Biol. 2019 Mar 15;8(3):521-531

    Insert

    TDK gene promoter and dCas9
    

    Use

    CRISPR

    Tags

    Expression

    Bacterial

    Mutation

    Promoter

    TDK gene promoter

    Available since

    Jan. 18, 2019

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge