12,469 results

1. SP65U1-135a-1

   Plasmid

   #105819

   Purpose

   plasmid for the overexpression of miR-135a under the U1 expression cassette inserted in the pSP65 plasmid

   Depositor

   Cecilia Mannironi

   Article

   Mannironi et al PLoS One. 2013 Sep 4;8(9):e73385. doi: 1

   Insert

   MIRNA135A1 (Mir135a-1 Mouse)
   

   Use

   Tags

   Expression

   Mammalian

   Mutation

   Promoter

   U1

   Available since

   Jan. 26, 2018

   Availability

   Academic Institutions and Nonprofits only

   

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2. p243_LTJ_4kbCD45.1Template

   Plasmid

   #82663

   Purpose

   4kb HDR template for murine CD45.1

   Depositor

   Lukas Jeker

   Article

   Kornete et al J Immunol. 2018 Feb 14. pii: jimmunol.17

   Insert

   4kb genomic DNA sequence from murine CD45.1
   

   Use

   Hdr template for gene editing

   Tags

   Expression

   Mutation

   Promoter

   Available since

   Jan. 17, 2018

   Availability

   Academic Institutions and Nonprofits only

   

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3. p206_LTJ_sgRNACD45.2_R3

   Plasmid

   #82674

   Purpose

   sgRNA targeting murine CD45.2 region 3. Co-expresses SpCas9-2A-EGFP.

   Depositor

   Lukas Jeker

   Article

   Kornete et al J Immunol. 2018 Feb 14. pii: jimmunol.17

   Insert

   sgRNA targeting CD45.2 region 3
   

   Use

   CRISPR

   Tags

   Expression

   Mammalian

   Mutation

   Promoter

   U6

   Available since

   Jan. 17, 2018

   Availability

   Academic Institutions and Nonprofits only

   

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4. pUAST-Myc-mSesn2 (1186)

   Plasmid

   #66920

   Purpose

   expression of mouse Sesn2 in drosophila

   Depositor

   Michael Karin, Jun Hee Lee

   Article

   Lee et al Science. 2010 Mar 5;327(5970):1223-8. do

   Insert

   Sesn2 (Sesn2 Mouse)
   

   Use

   Tags

   Myc

   Expression

   Insect

   Mutation

   Promoter

   HS promoter

   Available since

   Dec. 26, 2017

   Availability

   Academic Institutions and Nonprofits only

   

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5. pGEX-4T-1 mSesn1 (1189)

   Plasmid

   #66917

   Purpose

   bacterial expression of mouse Sesn1

   Depositor

   Michael Karin, Jun Hee Lee

   Article

   Lee et al Cell Metab. 2012 Sep 5;16(3):311-21. doi

   Insert

   Sesn1 (Sesn1 Mouse)
   

   Use

   Tags

   GST

   Expression

   Bacterial

   Mutation

   Promoter

   tac

   Available since

   Dec. 18, 2017

   Availability

   Academic Institutions and Nonprofits only

   

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6. pGEX-4T-1 mSesn2 (1190)

   Plasmid

   #66916

   Purpose

   bacterial expression of mouse Sesn2

   Depositor

   Michael Karin, Jun Hee Lee

   Article

   Park et al Nat Commun. 2014 Jun 20;5:4233. doi: 10.

   Insert

   Sesn2 (Sesn2 Mouse)
   

   Use

   Tags

   GST

   Expression

   Bacterial

   Mutation

   Promoter

   tac

   Available since

   Dec. 18, 2017

   Availability

   Academic Institutions and Nonprofits only

   

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7. AAV-KrasG13R/sgKras/Cre

   Plasmid

   #99858

   Purpose

   Expresses Cre-recombinase, a barcoded HDR template to introduce a G13R mutation into the endogenous Kras locus, and a Kras-targeting sgRNA to enhance HDR.

   Depositor

   Monte Winslow

   Article

   Winters et al Nat Commun. 2017 Dec 12;8(1):2053. doi:

   Insert

   Kras (Kras Mouse)
   

   Use

   AAV and Cre/Lox

   Tags

   Expression

   Mammalian

   Mutation

   AvrII site (CAAAGG>CCTAGG), PAM/sgRNA mutation…

   Promoter

   Available since

   Dec. 13, 2017

   Availability

   Academic Institutions and Nonprofits only

   

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8. pLKO.1P shNfs1

   Plasmid

   #102967

   Purpose

   Suppression of mNfs1

   Depositor

   Richard Possemato

   Article

   Alvarez et al Nature. 2017 Nov 22. doi: 10.1038/nature

   Insert

   shNfs1
   

   Use

   Lentiviral and RNAi

   Tags

   Expression

   Mutation

   Promoter

   Available since

   Nov. 22, 2017

   Availability

   Academic Institutions and Nonprofits only

   

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9. pLKO.1-shDnd1-No1

   Plasmid

   #70058

   Purpose

   TRC lentiviral vector for shRNA against mouse Dnd1 #1

   Depositor

   Thomas Tuschl

   Article

   Yamaji et al Nature. 2017 Mar 23;543(7646):568-572. d

   Insert

   Dnd1 (Dnd1 Mouse)
   

   Use

   Lentiviral

   Tags

   Expression

   Mammalian

   Mutation

   Promoter

   EF1alpha

   Available since

   Nov. 22, 2017

   Availability

   Academic Institutions and Nonprofits only

   

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10. pLKO.1-shDnd1-No3

    Plasmid

    #70060

    Purpose

    TRC lentiviral vector for shRNA against mouse Dnd1 #3

    Depositor

    Thomas Tuschl

    Article

    Yamaji et al Nature. 2017 Mar 23;543(7646):568-572. d

    Insert

    Dnd1 (Dnd1 Mouse)
    

    Use

    Lentiviral

    Tags

    Expression

    Mammalian

    Mutation

    Promoter

    EF1alpha

    Available since

    Nov. 22, 2017

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

11. pLKO.1-shDnd1-No4

    Plasmid

    #70065

    Purpose

    TRC lentiviral vector for shRNA against mouse Dnd1 #4

    Depositor

    Thomas Tuschl

    Article

    Yamaji et al Nature. 2017 Mar 23;543(7646):568-572. d

    Insert

    Dnd1 (Dnd1 Mouse)
    

    Use

    Lentiviral

    Tags

    Expression

    Mammalian

    Mutation

    Promoter

    EF1alpha

    Available since

    Nov. 22, 2017

    Availability

    Academic Institutions and Nonprofits only

12. pLKO.1-shDnd1-No5

    Plasmid

    #70066

    Purpose

    TRC lentiviral vector for shRNA against mouse Dnd1 #5

    Depositor

    Thomas Tuschl

    Article

    Yamaji et al Nature. 2017 Mar 23;543(7646):568-572. d

    Insert

    Dnd1 (Dnd1 Mouse)
    

    Use

    Lentiviral

    Tags

    Expression

    Mammalian

    Mutation

    Promoter

    EF1alpha

    Available since

    Nov. 22, 2017

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

13. pLKO.1-shDnd1-No6

    Plasmid

    #70067

    Purpose

    TRC lentiviral vector for shRNA against mouse Dnd1 #6

    Depositor

    Thomas Tuschl

    Article

    Yamaji et al Nature. 2017 Mar 23;543(7646):568-572. d

    Insert

    Dnd1 (Dnd1 Mouse)
    

    Use

    Lentiviral

    Tags

    Expression

    Mammalian

    Mutation

    Promoter

    EF1alpha

    Available since

    Nov. 22, 2017

    Availability

    Academic Institutions and Nonprofits only

14. pLKO.1-shDnd1-No8

    Plasmid

    #70069

    Purpose

    TRC lentiviral vector for shRNA against mouse Dnd1 #8

    Depositor

    Thomas Tuschl

    Article

    Yamaji et al Nature. 2017 Mar 23;543(7646):568-572. d

    Insert

    Dnd1 (Dnd1 Mouse)
    

    Use

    Lentiviral

    Tags

    Expression

    Mammalian

    Mutation

    Promoter

    EF1alpha

    Available since

    Nov. 22, 2017

    Availability

    Academic Institutions and Nonprofits only

15. pLVE-FH-Dnd1-IN

    Plasmid

    #70072

    Purpose

    2nd gen lentiviral vector. Cre-removable and tet/dox-controllable expression of FLAG-HA-tagged murine Dnd1 in mammalian cells.

    Depositor

    Thomas Tuschl

    Article

    Yamaji et al Nature. 2017 Mar 23;543(7646):568-572. d

    Insert

    Dnd1 (Dnd1 Mouse)
    

    Use

    Cre/Lox and Lentiviral

    Tags

    FLAG and HA

    Expression

    Mammalian

    Mutation

    Promoter

    EF1alpha

    Available since

    Nov. 22, 2017

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

16. Adeno FT

    Plasmid

    #101824

    Purpose

    Adenovirus for the expression of gRNAs targeting intron 17 of murine Fgfr3 and intron 6 of murine Tacc3

    Depositor

    Andrea Ventura

    Article

    Cook et al Nat Commun. 2017 Jul 11;8:15987. doi: 10

    Insert

    U6_sgRNA(Fgfr3)_U6_sgRNA(Tacc3)_CBh_FLAG-Cas9 (Fgfr3, Tacc3 Mouse)
    

    Use

    Adenoviral

    Tags

    FLAG-Cas9

    Expression

    Mutation

    Promoter

    U6 and CBh

    Available since

    Nov. 8, 2017

    Availability

    Academic Institutions and Nonprofits only

17. Adeno BN

    Plasmid

    #101823

    Purpose

    Adenovirus for the expression of gRNAs targeting intron 13 of murine Bcan and intron 10 of murine Ntrk1

    Depositor

    Andrea Ventura

    Article

    Cook et al Nat Commun. 2017 Jul 11;8:15987. doi: 10

    Insert

    U6_sgRNA(Bcan)_U6_sgRNA(Ntrk1)_CBh_FLAG-Cas9 (Bcan, Ntrk1 Mouse)
    

    Use

    Adenoviral

    Tags

    FLAG-Cas9

    Expression

    Mutation

    Promoter

    Available since

    Nov. 8, 2017

    Availability

    Academic Institutions and Nonprofits only

18. HA-mus-Bnip3_Exon(2+3)

    Plasmid

    #100794

    Purpose

    Mammalian expression of Bnip3_Exon2+3 splice variant

    Depositor

    Joseph Gordon

    Insert

    mouse-BNIP3_Exon(2+3) (Bnip3 Mouse)
    

    Use

    Tags

    HA

    Expression

    Mammalian

    Mutation

    Exon2 and Exon3 deletion

    Promoter

    CMV

    Available since

    Nov. 1, 2017

    Availability

    Academic Institutions and Nonprofits only

    

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19. pCDH-CMV-Tmeff2-3xFlag-EF1-nlsCopGFP

    Plasmid

    #99729

    Purpose

    overexpression of Tmeff2 and CopGFP

    Depositor

    Mengsheng Qiu

    Article

    Huang et al Sci Rep. 2017 Mar 23;7(1):337. doi: 10.1

    Insert

    Tmeff2 (Tmeff2 Mouse)
    

    Use

    Tags

    3xFLAG

    Expression

    Mammalian

    Mutation

    Promoter

    CMV

    Available since

    Oct. 17, 2017

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

20. p250_LTJ_2kbFoxp3wtTemplate

    Plasmid

    #82665

    Purpose

    2kb HDR template for murine wildtype Foxp3

    Depositor

    Lukas Jeker

    Article

    Kornete et al J Immunol. 2018 Feb 14. pii: jimmunol.17

    Insert

    2kb genomic DNA sequence from murine wildtype Foxp3
    

    Use

    Hdr template for gene editing

    Tags

    Expression

    Mutation

    Promoter

    Available since

    Oct. 6, 2017

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

21. pFUSEss-CHIg-mM-Arg210Ala_M18

    Plasmid

    #91734

    Purpose

    Expression plasmid coding for mutated heavy chain of mouse IgM antibody specific to antigen B of the ABO blood group system, clone M18. Mutation: Arg210Ala (EU numbering).

    Depositor

    Joanna Bereta

    Article

    Klaus et al Sci Rep. 2018 Jan 11;8(1):519. doi: 10.1

    Insert

    immunoglobulin heavy constant mu (Ighm Mouse)
    

    Use

    Tags

    Expression

    Mammalian

    Mutation

    Arg210 changed to Ala (EU numbering)

    Promoter

    hEF1-HTLV prom

    Available since

    Oct. 4, 2017

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

22. HA-mus-Bnip3_deltaExon3

    Plasmid

    #100793

    Purpose

    Mammalian expression of Bnip3_deltaExon3 splice variant

    Depositor

    Joseph Gordon

    Article

    Diehl-Jones et al J Pediatr Gastroenterol Nutr. 2015 Nov;6

    Insert

    mouse-Bnip3_deltaExon3 (Bnip3 Mouse)
    

    Use

    Tags

    HA

    Expression

    Mammalian

    Mutation

    Exon3 deletion

    Promoter

    CMV

    Available since

    Sept. 11, 2017

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

23. pLgw NKX2-5-V5-EcoDam

    Plasmid

    #98597

    Purpose

    Mammalian DamID lentiviral vector for NKX2-5 with Dam-V5 using Gateway cloning

    Depositor

    Richard Harvey

    Article

    Bouveret et al Elife. 2015 Jul 6;4. doi: 10.7554/eLife.

    Insert

    NKX2-5 (Nkx2-5 Mouse)
    

    Use

    Lentiviral; Damid

    Tags

    V5 and Dam (DNA adenine methyltransferase)

    Expression

    Mammalian

    Mutation

    Promoter

    Heat Shock Minimal Promoter

    Available since

    Sept. 11, 2017

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

24. pEGFP-mSPDEF deltaNC2

    Plasmid

    #100869

    Purpose

    Mammalian expression of mouse SPDEF truncation

    Depositor

    Noah Shroyer

    Article

    Lo et al Gastroenterology. 2017 Jul;153(1):205-21

    Insert

    Spdef (Spdef Mouse)
    

    Use

    Tags

    EGFP

    Expression

    Mammalian

    Mutation

    truncated protein 70-238aa

    Promoter

    CMV

    Available since

    Sept. 5, 2017

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

25. pEGFP-mSPDEF deltaC2

    Plasmid

    #100867

    Purpose

    Mammalian expression of mouse SPDEF truncation

    Depositor

    Noah Shroyer

    Article

    Lo et al Gastroenterology. 2017 Jul;153(1):205-21

    Insert

    Spdef (Spdef Mouse)
    

    Use

    Tags

    EGFP

    Expression

    Mammalian

    Mutation

    truncated protein 1-238aa

    Promoter

    CMV

    Available since

    Sept. 5, 2017

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

26. pEGFP-mSPDEF deltaN5

    Plasmid

    #100865

    Purpose

    Mammalian expression of mouse SPDEF truncation

    Depositor

    Noah Shroyer

    Article

    Lo et al Gastroenterology. 2017 Jul;153(1):205-21

    Insert

    Spdef (Spdef Mouse)
    

    Use

    Tags

    EGFP

    Expression

    Mammalian

    Mutation

    truncated protein 100-325aa

    Promoter

    CMV

    Available since

    Sept. 5, 2017

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

27. pEGFP-mSPDEF deltaN4

    Plasmid

    #100864

    Purpose

    Mammalian expression of mouse SPDEF truncation

    Depositor

    Noah Shroyer

    Article

    Lo et al Gastroenterology. 2017 Jul;153(1):205-21

    Insert

    Spdef (Spdef Mouse)
    

    Use

    Tags

    EGFP

    Expression

    Mammalian

    Mutation

    truncated protein 85-325aa

    Promoter

    CMV

    Available since

    Sept. 5, 2017

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

28. pEGFP-mSPDEF deltaN3

    Plasmid

    #100863

    Purpose

    Mammalian expression of mouse SPDEF truncation

    Depositor

    Noah Shroyer

    Article

    Lo et al Gastroenterology. 2017 Jul;153(1):205-21

    Insert

    Spdef (Spdef Mouse)
    

    Use

    Tags

    EGFP

    Expression

    Mammalian

    Mutation

    truncated protein 70-325aa

    Promoter

    CMV

    Available since

    Sept. 5, 2017

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

29. pEGFP-mSPDEF deltaN2

    Plasmid

    #100862

    Purpose

    Mammalian expression of mouse SPDEF truncation

    Depositor

    Noah Shroyer

    Article

    Lo et al Gastroenterology. 2017 Jul;153(1):205-21

    Insert

    Spdef (Spdef Mouse)
    

    Use

    Tags

    EGFP

    Expression

    Mammalian

    Mutation

    truncated protein 55-325aa

    Promoter

    CMV

    Available since

    Sept. 5, 2017

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

30. pFUSEss-CHIg-mM-Asn209Arg_M18

    Plasmid

    #91740

    Purpose

    Expression plasmid coding for mutated heavy chain of mouse IgM antibody specific to antigen B of the ABO blood group system, clone M18. Mutation: Asn209Arg (EU numbering).

    Depositor

    Joanna Bereta

    Article

    Klaus et al Sci Rep. 2018 Jan 11;8(1):519. doi: 10.1

    Insert

    immunoglobulin heavy constant mu (Ighm Mouse)
    

    Use

    Tags

    Expression

    Mammalian

    Mutation

    Asn209 changed to Arg (EU numbering)

    Promoter

    hEF1-HTLV prom

    Available since

    Aug. 22, 2017

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge