We narrowed to 2,493 results for: ERK

1. InsRA-TagBFP

   Plasmid

   #79791

   Purpose

   Insulin receptor isoform A with a inter-domain TagBFP tag at extracellular region (between furin-like domain and transmembrane domain). For imaging insulin receptor trafficing.

   Depositor

   James Johnson

   Article

   Boothe et al Mol Metab. 2016 Feb 10;5(5):366-78. doi:

   Insert

   InsRA (INSR Human)
   

   Use

   Tags

   TagBFP extracellular

   Expression

   Mammalian

   Mutation

   Promoter

   CMV

   Available since

   Aug. 5, 2016

   Availability

   Industry, Academic Institutions, and Nonprofits

   

   Enlarge

2. InsRA-EBFP2

   Plasmid

   #79797

   Purpose

   Insulin receptor isoform A with a inter-domain EBFP2 tag at extracellular region (between furin-like domain and transmembrane domain). For imaging insulin receptor trafficing.

   Depositor

   James Johnson

   Article

   Boothe et al Mol Metab. 2016 Feb 10;5(5):366-78. doi:

   Insert

   InsRA (INSR Human)
   

   Use

   Tags

   EBFP2 extracellular

   Expression

   Mammalian

   Mutation

   Promoter

   CMV

   Available since

   Aug. 5, 2016

   Availability

   Industry, Academic Institutions, and Nonprofits

   

   Enlarge

3. GFP-P2A-CIAR_pLenti_CMV_Puro

   Plasmid

   #86503

   Purpose

   Lenti plasmid for generating CIAR expressing stable cell lines

   Depositor

   Dustin Maly

   Article

   Rose et al Nat Chem Biol. 2016 Nov 21. doi: 10.1038

   Insert

   GFP-P2A-CIAR (SOS1 Human)
   

   Use

   Lentiviral

   Tags

   Expression

   Mammalian

   Mutation

   T968L in SOScat

   Promoter

   CMV

   Available since

   Feb. 8, 2017

   Availability

   Academic Institutions and Nonprofits only

   

   Enlarge

4. CRAF_S259A_pcDNA3.1

   Plasmid

   #86505

   Purpose

   Expresses CRAF_S259A in mammalian cells

   Depositor

   Dustin Maly

   Article

   Rose et al Nat Chem Biol. 2016 Nov 21. doi: 10.1038

   Insert

   CRAF (RAF1 Human)
   

   Use

   Tags

   FLAG

   Expression

   Mammalian

   Mutation

   S259A

   Promoter

   CMV

   Available since

   Feb. 8, 2017

   Availability

   Academic Institutions and Nonprofits only

   

   Enlarge

5. pTag-RFP-C-h-Rab4a-c-Myc

   Plasmid

   #79800

   Purpose

   Express TagRFP labeled human Rab5a (GTPase located on recycling endosomal membranes).

   Depositor

   James Johnson

   Article

   Boothe et al Mol Metab. 2016 Feb 10;5(5):366-78. doi:

   Insert

   Rab4a (RAB4A Human)
   

   Use

   Tags

   TagRFP and myc

   Expression

   Mammalian

   Mutation

   Promoter

   CMV

   Available since

   July 22, 2016

   Availability

   Industry, Academic Institutions, and Nonprofits

   

   Enlarge

6. pEBG-MKK4-S255D/T259E (GST)

   Plasmid

   #21566

   Depositor

   Leonard Zon

   Article

   Sanchez et al Nature. . 372(6508):794-8.

   Insert

   mitogen-activated protein kinase kinase 4 (Map2k4 Mouse)
   

   Use

   Tags

   GST

   Expression

   Mammalian

   Mutation

   Serine 255 to Aspartic Acid, Threonine 259 to Gl…

   Promoter

   Available since

   July 17, 2009

   Availability

   Academic Institutions and Nonprofits only

7. pEBG-MKK4-S255E/T259D (GST)

   Plasmid

   #21565

   Depositor

   Leonard Zon

   Article

   Sanchez et al Nature. . 372(6508):794-8.

   Insert

   mitogen-activated protein kinase kinase 4 (Map2k4 Mouse)
   

   Use

   Tags

   GST

   Expression

   Mammalian

   Mutation

   Serine 255 to Glutamic Acid, Threonine 259 to As…

   Promoter

   Available since

   July 22, 2009

   Availability

   Academic Institutions and Nonprofits only

8. CIAR_pcDNA5/FRT/TO

   Plasmid

   #86502

   Purpose

   Expresses CIAR in mammalian cells. Used to generate Flp-In stables.

   Depositor

   Dustin Maly

   Article

   Rose et al Nat Chem Biol. 2016 Nov 21. doi: 10.1038

   Insert

   CIAR (SOS1 Human)
   

   Use

   Frt

   Tags

   Expression

   Mammalian

   Mutation

   T968L in SOScat

   Promoter

   CMV (tet operator)

   Available since

   Feb. 8, 2017

   Availability

   Academic Institutions and Nonprofits only

   

   Enlarge

9. shCTL-mlpx-puro

   Plasmid

   #65232

   Purpose

   encodes a non-targeting control shRNA

   Depositor

   Gerardo Ferbeyre

   Article

   Deschenes-Simard et al Genes Dev. 2013 Apr 15;27(8):900-15. doi

   Insert

   non-coding shRNA
   

   Use

   Tags

   Expression

   Mammalian

   Mutation

   Promoter

   PGK

   Available since

   Aug. 12, 2015

   Availability

   Academic Institutions and Nonprofits only

   

   Enlarge

10. pMP108 Nanog-Venus-2a-mCherry

    Plasmid

    #159743

    Purpose

    Nanog targeting vector to insert fluorescent reporter of protein and gene expression levels from endogenous locus in mouse embryonic stem cells. Please see depositor comments for more detail.

    Depositor

    Sergi Regot

    Article

    Pokrass et al Dev Cell. 2020 Nov 9;55(3):328-340.e5. d

    Insert

    Nanog homeobox (Nanog Mouse)
    

    Use

    Mouse Targeting

    Tags

    Venus-2a-mCherry

    Expression

    Mutation

    Promoter

    Available since

    July 8, 2021

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

11. pCMV5 N539

    Plasmid

    #25972

    Depositor

    Rob Lewis

    Article

    Joneson et al J Biol Chem. 1998 Mar 27. 273(13):7743-8

    Insert

    Kinase suppressor of Ras 1 (Ksr1 Mouse)
    

    Use

    Tags

    Flag

    Expression

    Mammalian

    Mutation

    Deleted amino acids 540-873

    Promoter

    Available since

    Aug. 13, 2010

    Availability

    Academic Institutions and Nonprofits only

12. pCMV5 C540

    Plasmid

    #25971

    Depositor

    Rob Lewis

    Article

    Joneson et al J Biol Chem. 1998 Mar 27. 273(13):7743-8

    Insert

    Kinase suppressor of Ras 1 (Ksr1 Mouse)
    

    Use

    Tags

    Flag

    Expression

    Mammalian

    Mutation

    Deletes amino acids 1-539

    Promoter

    Available since

    Aug. 24, 2010

    Availability

    Academic Institutions and Nonprofits only

13. pcDNA3 FLAG FBXO31

    Plasmid

    #236429

    Purpose

    transient overexpression of FBXO31 in mammalian cells

    Depositor

    Michele Pagano

    Article

    Duan et al Cell Rep. 2021 Oct 19;37(3):109870. doi:

    Insert

    FBXO31 (FBXO31 Human)
    

    Use

    Tags

    FLAG

    Expression

    Mammalian

    Mutation

    Promoter

    Available since

    May 28, 2025

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

14. pPBbleo-miRFP703-eDHFR(69K6)-Tiam1(DH-PH)

    Plasmid

    #186703

    Purpose

    Mammalian expression of Tiam1(DH-PH) fused to miRFP703-eDHFR(69K6)

    Depositor

    Michiyuki Matsuda

    Article

    Hino et al Dev Cell. 2022 Oct 10;57(19):2290-2304.e

    Insert

    miRFP703-eDHFR(69K6)-Tiam1(DH-PH)
    

    Use

    Tags

    Expression

    Mammalian

    Mutation

    Promoter

    Available since

    Nov. 15, 2022

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

15. pX459-dTLN1 exon

    Plasmid

    #176033

    Purpose

    A vector for the CRISPR-Cas9 system targeting an exon of dog TLN1 (talin1)

    Depositor

    Michiyuki Matsuda

    Article

    Hino et al Dev Cell. 2022 Oct 10;57(19):2290-2304.e

    Insert

    A gRNA targeting the dog TLN1 gene and the cDNA of Cas9 (TLN1 )
    

    Use

    CRISPR

    Tags

    Expression

    Mammalian

    Mutation

    Promoter

    Available since

    Oct. 27, 2022

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

16. pX459-dTLN1 intron

    Plasmid

    #176224

    Purpose

    A vector for the CRISPR-Cas9 system targeting an intron of dog TLN1 (talin1)

    Depositor

    Michiyuki Matsuda

    Article

    Hino et al Dev Cell. 2022 Oct 10;57(19):2290-2304.e

    Insert

    A gRNA targeting the dog TLN1 gene and the cDNA of Cas9 (TLN1 )
    

    Use

    CRISPR

    Tags

    Expression

    Mammalian

    Mutation

    Promoter

    Available since

    Oct. 27, 2022

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

17. AdMKP-3 S159AS197A

    Plasmid

    #131523

    Purpose

    Expresses MKP-3 with S159A mutation and S197A mutation in mammalian cells

    Depositor

    Haiyan Xu

    Article

    Feng et al Mol Cell Endocrinol. 2012 Sep 25;361(1-2

    Insert

    Mitogen-activated protein kinase phosphatase 3 (Dusp6 Mouse)
    

    Use

    Adenoviral

    Tags

    No

    Expression

    Mutation

    changed Serine 159 to Alanine and Serine 197 to A…

    Promoter

    CMV

    Available since

    Oct. 22, 2019

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

18. xCIAR_pcDNA5/FRT/TO

    Plasmid

    #86504

    Purpose

    Expresses inactive control CIAR (xCIAR) in mammalian cells. Used to generate Flp-In stables.

    Depositor

    Dustin Maly

    Article

    Rose et al Nat Chem Biol. 2016 Nov 21. doi: 10.1038

    Insert

    xCIAR (SOS1 Human)
    

    Use

    Frt

    Tags

    Expression

    Mammalian

    Mutation

    F929A and T968L in SOScat

    Promoter

    CMV (tet operator)

    Available since

    Feb. 8, 2017

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

19. shCTL-mlpx-neo

    Plasmid

    #65233

    Purpose

    encodes a non-targeting control shRNA

    Depositor

    Gerardo Ferbeyre

    Article

    Deschenes-Simard et al Genes Dev. 2013 Apr 15;27(8):900-15. doi

    Insert

    non-coding shRNA
    

    Use

    Tags

    Expression

    Mammalian

    Mutation

    Promoter

    PGK

    Available since

    Aug. 12, 2015

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

20. pCR-Flag-IKKalpha

    Plasmid

    #15467

    Depositor

    Hiroyasu Nakano

    Article

    Nakano et al Proc Natl Acad Sci U S A. 1998 Mar 31. 9

    Insert

    IkB kinase alpha (Chuk Mouse)
    

    Use

    Tags

    Flag

    Expression

    Mammalian

    Mutation

    Promoter

    Available since

    Oct. 10, 2007

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

21. pCR-Flag-IKKbeta

    Plasmid

    #15465

    Depositor

    Hiroyasu Nakano

    Article

    Nakano et al Proc Natl Acad Sci U S A. 1998 Mar 31. 9

    Insert

    IkB kinase beta (Ikbkb Mouse)
    

    Use

    Tags

    Flag

    Expression

    Mammalian

    Mutation

    Promoter

    Available since

    Oct. 10, 2007

    Availability

    Academic Institutions and Nonprofits only

22. pCR-HA-IKKbeta

    Plasmid

    #15470

    Depositor

    Hiroyasu Nakano

    Article

    Nakano et al Proc Natl Acad Sci U S A. 1998 Mar 31. 9

    Insert

    IkB kinase beta (Ikbkb Mouse)
    

    Use

    Tags

    HA

    Expression

    Mammalian

    Mutation

    Promoter

    Available since

    Oct. 10, 2007

    Availability

    Academic Institutions and Nonprofits only

23. pSLIK 3xHA-MKK6-EE neo

    Plasmid

    #47546

    Purpose

    Lentiviral expression vector for an inducible 3xHA-tagged constitutively active MKK6 mutant

    Depositor

    Kevin Janes

    Article

    Jensen et al Cell Host Microbe. 2013 Jan 16;13(1):67-

    Insert

    MKK6-EE (MAP2K6 Human)
    

    Use

    Lentiviral

    Tags

    3XHA

    Expression

    Mammalian

    Mutation

    S207E, T211E

    Promoter

    Available since

    Sept. 13, 2013

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

24. pSLIK MEK5-DD-mRFP1 neo

    Plasmid

    #47548

    Purpose

    Lentiviral expression vector for an inducible mRFP1-tagged constitutively active MEK5 mutant

    Depositor

    Kevin Janes

    Article

    Jensen et al Cell Host Microbe. 2013 Jan 16;13(1):67-

    Insert

    MEK5-DD-mRFP1 (MAP2K5 Human)
    

    Use

    Lentiviral

    Tags

    mRFP

    Expression

    Mammalian

    Mutation

    S311D, T315D

    Promoter

    Available since

    Aug. 28, 2013

    Availability

    Academic Institutions and Nonprofits only

25. pCR-Flag-IKKalpha-KM

    Plasmid

    #15468

    Depositor

    Hiroyasu Nakano

    Article

    Nakano et al Proc Natl Acad Sci U S A. 1998 Mar 31. 9

    Insert

    IkB kinase alpha-KM (Chuk Mouse)
    

    Use

    Tags

    Flag

    Expression

    Mammalian

    Mutation

    changed Lysine at 44 to Alanine

    Promoter

    Available since

    Oct. 10, 2007

    Availability

    Academic Institutions and Nonprofits only

26. pCR-HA-IKKalpha

    Plasmid

    #15469

    Depositor

    Hiroyasu Nakano

    Article

    Nakano et al Proc Natl Acad Sci U S A. 1998 Mar 31. 9

    Insert

    IkB kinase alpha (Chuk Mouse)
    

    Use

    Tags

    HA

    Expression

    Mammalian

    Mutation

    Promoter

    Available since

    Oct. 10, 2007

    Availability

    Academic Institutions and Nonprofits only

27. pCR-Flag-IKKbeta-KM

    Plasmid

    #15466

    Depositor

    Hiroyasu Nakano

    Article

    Nakano et al Proc Natl Acad Sci U S A. 1998 Mar 31. 9

    Insert

    IkB kinase beta-KM (Ikbkb Mouse)
    

    Use

    Tags

    Flag

    Expression

    Mammalian

    Mutation

    changed Lysine at 44 to Alanine

    Promoter

    Available since

    Oct. 10, 2007

    Availability

    Academic Institutions and Nonprofits only

28. pX459-dCTNNA1

    Plasmid

    #176032

    Purpose

    A knock-out vector for dog CTNNA1 (alpha-1-catenin)

    Depositor

    Michiyuki Matsuda

    Article

    Hino et al Dev Cell. 2022 Oct 10;57(19):2290-2304.e

    Insert

    A gRNA targeting the dog CTNNA1 (alpha-1-catenin) gene and the cDNA of Cas9 (CTNNA1 )
    

    Use

    CRISPR

    Tags

    Expression

    Mammalian

    Mutation

    Promoter

    Available since

    Oct. 27, 2022

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

29. pCR-Myc-IKKalpha

    Plasmid

    #19739

    Depositor

    Hiroyasu Nakano

    Article

    Nakano et al Proc Natl Acad Sci U S A. 1998 Mar 31. 9

    Insert

    IkB kinase alpha (Chuk Mouse)
    

    Use

    Tags

    Myc

    Expression

    Mammalian

    Mutation

    Promoter

    Available since

    Oct. 27, 2008

    Availability

    Academic Institutions and Nonprofits only

30. CRAF_S29A_pcDNA3.1

    Plasmid

    #86506

    Purpose

    Expresses CRAF_S29A in mammalian cells [Edit]

    Depositor

    Dustin Maly

    Article

    Rose et al Nat Chem Biol. 2016 Nov 21. doi: 10.1038

    Insert

    CRAF (RAF1 Human)
    

    Use

    Tags

    FLAG

    Expression

    Mammalian

    Mutation

    S29A

    Promoter

    CMV

    Available since

    Feb. 1, 2017

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

31. pEN_TT MEK5-DD-mRFP1

    Plasmid

    #47547

    Purpose

    Gateway entry vector for an inducible mRFP1-tagged constitutively active MEK5 mutant

    Depositor

    Kevin Janes

    Article

    Jensen et al Cell Host Microbe. 2013 Jan 16;13(1):67-

    Insert

    MEK5-DD (MAP2K5 Human)
    

    Use

    Entry vector

    Tags

    mRFP

    Expression

    Mutation

    S311D, T315D

    Promoter

    Available since

    Sept. 6, 2013

    Availability

    Academic Institutions and Nonprofits only

32. pCR-HA-IKKalphad17

    Plasmid

    #19738

    Depositor

    Hiroyasu Nakano

    Article

    Nakano et al Proc Natl Acad Sci U S A. 1998 Mar 31. 9

    Insert

    IkB kinase alpha (Chuk Mouse)
    

    Use

    Tags

    HA

    Expression

    Mammalian

    Mutation

    Splice variant lacking 17 amino acids at the C-te…

    Promoter

    Available since

    Nov. 12, 2008

    Availability

    Academic Institutions and Nonprofits only

33. pEN_TT 3xHA-MKK6-EE

    Plasmid

    #47544

    Purpose

    Gateway entry vector for an inducible 3xHA-tagged constitutively active MKK6 mutant

    Depositor

    Kevin Janes

    Article

    Jensen et al Cell Host Microbe. 2013 Jan 16;13(1):67-

    Insert

    3xHA-MKK6-EE (MAP2K6 Human)
    

    Use

    Entry vector

    Tags

    3XHA

    Expression

    Mutation

    S207E, T211E

    Promoter

    Available since

    Sept. 6, 2013

    Availability

    Academic Institutions and Nonprofits only

34. pX459-dMET

    Plasmid

    #176031

    Purpose

    A knock-out vector for dog MET

    Depositor

    Michiyuki Matsuda

    Article

    Hino et al Dev Cell. 2022 Oct 10;57(19):2290-2304.e

    Insert

    A gRNA targeting the dog MET gene and the cDNA of Cas9 (MET )
    

    Use

    CRISPR

    Tags

    Expression

    Mammalian

    Mutation

    Promoter

    Available since

    Oct. 27, 2022

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

35. SHIP2-WT

    Plasmid

    #214907

    Purpose

    expression of the full length variants of the SHIP2

    Depositor

    Pavel Krejčí

    Article

    Fafilek et al Sci Signal. 2018 Sep 18;11(548):eaap8608

    Insert

    human SHIP2 (INPPL1 Human)
    

    Use

    Tags

    V5/His

    Expression

    Mammalian

    Mutation

    Promoter

    CMV

    Available since

    March 19, 2024

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

36. SHIP2-ΔPS

    Plasmid

    #214901

    Purpose

    expression of the truncated variants of the SHIP2 without phosphatase domain

    Depositor

    Pavel Krejčí

    Article

    Fafilek et al Sci Signal. 2018 Sep 18;11(548):eaap8608

    Insert

    human SHIP2 delta aa 419-739 (INPPL1 Human)
    

    Use

    Tags

    V5/His

    Expression

    Mammalian

    Mutation

    delta 419-739aa

    Promoter

    CMV

    Available since

    March 19, 2024

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

37. MAPK1 gRNA (BRDN0001149093)

    Plasmid

    #77788

    Purpose

    3rd generation lentiviral gRNA plasmid targeting human MAPK1

    Depositor

    John Doench, David Root

    Article

    Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

    Insert

    MAPK1 (MAPK1 Human)
    

    Use

    CRISPR and Lentiviral

    Tags

    Expression

    Mammalian

    Mutation

    Promoter

    hU6

    Available since

    July 6, 2016

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

38. MAPK1 gRNA (BRDN0001147355)

    Plasmid

    #77787

    Purpose

    3rd generation lentiviral gRNA plasmid targeting human MAPK1

    Depositor

    John Doench, David Root

    Article

    Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

    Insert

    MAPK1 (MAPK1 Human)
    

    Use

    CRISPR and Lentiviral

    Tags

    Expression

    Mammalian

    Mutation

    Promoter

    hU6

    Available since

    July 6, 2016

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

39. MAPK1 gRNA (BRDN0001147498)

    Plasmid

    #77789

    Purpose

    3rd generation lentiviral gRNA plasmid targeting human MAPK1

    Depositor

    John Doench, David Root

    Article

    Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

    Insert

    MAPK1 (MAPK1 Human)
    

    Use

    CRISPR and Lentiviral

    Tags

    Expression

    Mammalian

    Mutation

    Promoter

    hU6

    Available since

    July 6, 2016

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

40. pCMV5-FLAG-MKK6-K82M

    Plasmid

    #21583

    Depositor

    John Kyriakis

    Article

    Yuasa et al J Biol Chem. 1998 Aug 28. 273(35):22681-

    Insert

    MKK6 (MAP2K6 Human)
    

    Use

    Tags

    FLAG

    Expression

    Mammalian

    Mutation

    lysine 82 to methionine

    Promoter

    Available since

    Nov. 24, 2009

    Availability

    Academic Institutions and Nonprofits only