We narrowed to 138 results for: sgrna

1. Bison sgRNA library

   Pooled Library

   #169942

   Purpose

   The BISON CRISPR library targets 713 E1, E2, and E3 ubiquitin ligases, deubiquitinases, and control genes and contains 2,852 guide RNAs. It was cloned into the pXPR003.

   Depositor

   Benjamin Ebert

   Article

   Slabicki et al Nature. 2020 Sep;585(7824):293-297. doi:

   Use

   Lentiviral

   Available since

   Sept. 9, 2021

   Availability

   Academic Institutions and Nonprofits only

2. BARBEKO sgRNA library

   Pooled Library

   #174163

   Purpose

   iBARed cytosine Base Editing-mediated gene KnockOut (BARBEKO) sgRNA library; This library leverages CRISPR cytosine base editors for genome-scale knockout screens.

   Depositor

   Wensheng Wei

   Article

   Xu et al Nat Biotechnol. 2021 Jun 21. pii: 10.103

   Expression

   Mammalian

   Species

   Homo sapiens

   Use

   CRISPR and Lentiviral

   Available since

   Aug. 31, 2021

   Availability

   Academic Institutions and Nonprofits only

3. UMI-sgRNA-TF

   Pooled Library

   #234819

   Purpose

   Unique molecular identifiers-linked sgRNA library targeting transcription factors (TFs) in mice.

   Depositor

   Benjamin Ebert

   Article

   Loke et al Blood. 2025 Jun 10:blood.2024028033. doi

   Expression

   Mammalian

   Species

   Mus musculus

   Use

   CRISPR and Lentiviral

   Available since

   June 11, 2025

   Availability

   Academic Institutions and Nonprofits only

4. UMI-sgRNA-CH

   Pooled Library

   #234820

   Purpose

   Unique molecular identifiers-linked sgRNA library targeting chromatin factors (CH) in mice.

   Depositor

   Benjamin Ebert

   Article

   Loke et al Blood. 2025 Jun 10:blood.2024028033. doi

   Expression

   Mammalian

   Species

   Mus musculus

   Use

   CRISPR and Lentiviral

   Available since

   June 11, 2025

   Availability

   Academic Institutions and Nonprofits only

5. Sabatini/Lander Lab Activity-Optimized Genome-wide Mouse sgRNA Library in pLenti-sgRNA

   Pooled Library

   #1000000096

   Purpose

   CRISPR gRNA knockout pooled library for targeting the mouse genome

   Depositor

   Eric Lander, David Sabatini

   Available since

   April 3, 2017

   Availability

   Academic Institutions and Nonprofits only

6. Sabatini/Lander Lab Activity-Optimized Genome-wide Human sgRNA Library in pLenti-sgRNA

   Pooled Library

   #1000000095

   Purpose

   CRISPR gRNA knockout pooled library for targeting the human genome

   Depositor

   Eric Lander, David Sabatini

   Available since

   April 3, 2017

   Availability

   Academic Institutions and Nonprofits only

7. Dual sgRNA CRISPRi Library

   Pooled Library

   #1000000192

   Depositor

   Jonathan Weissman

   Available since

   Sept. 30, 2022

   Availability

   Academic Institutions and Nonprofits only

8. Dual sgRNA CRISPRa Library

   Pooled Library

   #1000000193

   Depositor

   Jonathan Weissman

   Available since

   Sept. 30, 2022

   Availability

   Academic Institutions and Nonprofits only

9. sgRNA pool for Streptococcus pneumoniae

   Pooled Library

   #170432

   Purpose

   CRISPR library targeting S. pneumoniae D39V

   Depositor

   Jan-Willem Veening

   Article

   Liu et al Cell Host Microbe. 2021 Jan 13;29(1):107

   Expression

   Bacterial

   Use

   CRISPR

   Available since

   Aug. 31, 2021

   Availability

   Academic Institutions and Nonprofits only

10. psgRNA_EcoWG1

    Pooled Library

    #131625

    Purpose

    Improved genome-wide knockdown of E. coli genes

    Depositor

    David Bikard

    Article

    Calvo-Villamanan et al Nucleic Acids Res. 2020 Apr 30. pii: 582

    Expression

    Bacterial

    Species

    Escherichia coli

    Use

    CRISPR

    Available since

    May 12, 2020

    Availability

    Academic Institutions and Nonprofits only

11. Drosophila_sgRNA_group_2

    Pooled Library

    #134583

    Purpose

    Targets Drosophila orthologs of vertebrate genes that have undergone expansion in the vertebrate line

    Depositor

    Norbert Perrimon

    Article

    Viswanatha et al Elife. 2018 Jul 27;7. pii: 36333. doi: 1

    Expression

    Insect

    Species

    Drosophila melanogaster

    Use

    CRISPR

    Available since

    Feb. 25, 2020

    Availability

    Academic Institutions and Nonprofits only

12. Drosophila_sgRNA_group_3

    Pooled Library

    #134584

    Purpose

    Targets all other Drosophila genes not included in Groups 1 and 2

    Depositor

    Norbert Perrimon

    Article

    Viswanatha et al Elife. 2018 Jul 27;7. pii: 36333. doi: 1

    Expression

    Insect

    Species

    Drosophila melanogaster

    Use

    CRISPR

    Available since

    Feb. 25, 2020

    Availability

    Academic Institutions and Nonprofits only

13. Drosophila_sgRNA_group_1

    Pooled Library

    #134582

    Purpose

    Targets kinases, phosphatases, and Drosophila orthologs of drug targets

    Depositor

    Norbert Perrimon

    Article

    Viswanatha et al Elife. 2018 Jul 27;7. pii: 36333. doi: 1

    Expression

    Insect

    Species

    Drosophila melanogaster

    Use

    CRISPR

    Available since

    Feb. 25, 2020

    Availability

    Academic Institutions and Nonprofits only

14. E.coli_NC_sgRNA_lib

    Pooled Library

    #113146

    Purpose

    Genome-wide gRNA library for E. coli, non-targeting control

    Depositor

    Chong Zhang

    Article

    Wang et al Nat Commun. 2018 Jun 26;9(1):2475. doi:

    Expression

    Bacterial

    Available since

    May 14, 2019

    Availability

    Academic Institutions and Nonprofits only

15. Human sgRNA library Brunello in lentiCRISPRv2

    Pooled Library

    #73179

    Purpose

    Human sgRNA library in backbone lentiCRISPRv2 targeting 19,114 genes and containing 76,441 unique sgRNAs along with 1000 non-targeting controls

    Depositor

    David Root, John Doench

    Article

    Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

    Has Service

    Lentiviral Prep

    Expression

    Mammalian

    Use

    CRISPR and Lentiviral

    Available since

    Feb. 9, 2016

    Availability

    Academic Institutions and Nonprofits only

16. Mouse sgRNA library Brie in lentiCRISPRv2

    Pooled Library

    #73632

    Purpose

    Mouse sgRNA library in backbone lentiCRISPRv2 containing 78,637 unique sgRNAs targeting 19,674 genes along with 1000 non-targeting controls

    Depositor

    David Root, John Doench

    Article

    Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

    Expression

    Mammalian

    Use

    CRISPR and Lentiviral

    Available since

    Feb. 25, 2016

    Availability

    Academic Institutions and Nonprofits only

17. DNA repair library with 1,513 sgRNAs

    Pooled Library

    #177670

    Purpose

    CRISPR-interference (CRISPRi) library designed to target 476 genes involved in DNA repair and associated processes. It contains 1,513 sgRNAs and 60 non-targeting control sgRNAs.

    Depositor

    Brittany Adamson

    Article

    Chen et al Cell. 2021 Oct 28;184(22):5635-5652.e29.

    Expression

    Mammalian

    Species

    Homo sapiens

    Use

    CRISPR and Lentiviral

    Available since

    July 11, 2023

    Availability

    Academic Institutions and Nonprofits only

18. DNA repair library with 1,573 sgRNAs

    Pooled Library

    #177663

    Purpose

    CRISPR-interference (CRISPRi) library of 1,573 sgRNAs targeting 476 genes encoding factors involved in DNA repair and associated processes

    Depositor

    Brittany Adamson

    Article

    Hussmann et al Cell. 2021 Oct 28;184(22):5653-5669.e25.

    Species

    Homo sapiens

    Use

    CRISPR

    Available since

    July 11, 2023

    Availability

    Academic Institutions and Nonprofits only

19. Human Lentiviral sgRNA Library - Kinases

    Pooled Library

    #51044

    Purpose

    Sub-pool of Sabatini/Lander sgRNA library enriched for kinase targets.

    Depositor

    Eric Lander, David Sabatini

    Article

    Wang et al Science. 2014 Jan 3;343(6166):80-4. doi:

    Expression

    Mammalian

    Species

    Homo sapiens

    Use

    CRISPR and Lentiviral

    Available since

    Feb. 7, 2014

    Availability

    Academic Institutions and Nonprofits only

20. Human Lentiviral sgRNA Library - Nuclear

    Pooled Library

    #51047

    Purpose

    Sub-pool of Sabatini/Lander sgRNA library enriched for nuclear targets.

    Depositor

    Eric Lander, David Sabatini

    Article

    Wang et al Science. 2014 Jan 3;343(6166):80-4. doi:

    Expression

    Mammalian

    Species

    Homo sapiens

    Use

    CRISPR and Lentiviral

    Available since

    Feb. 7, 2014

    Availability

    Academic Institutions and Nonprofits only

21. Mouse messenger-RBP sgRNA library

    Pooled Library

    #169082

    Purpose

    CRISPR library targeting mouse genes

    Depositor

    Martin Turner

    Article

    Turner et al eLife. 2022 Apr 22;11. pii: 72313. doi:

    Expression

    Mammalian

    Species

    Mus musculus

    Use

    CRISPR and Lentiviral

    Available since

    Sept. 10, 2021

    Availability

    Academic Institutions and Nonprofits only

22. Human messenger-RBP sgRNA library

    Pooled Library

    #168791

    Purpose

    CRISPR library targets sub-pool of human mRNA binding proteins

    Depositor

    Martin Turner

    Article

    Turner et al CRISPR J. 2021 Jun;4(3):427-437. doi: 10

    Expression

    Mammalian

    Species

    Homo sapiens

    Use

    CRISPR and Lentiviral

    Available since

    July 30, 2021

    Availability

    Academic Institutions and Nonprofits only

23. Human Lentiviral sgRNA Library - Control

    Pooled Library

    #51048

    Purpose

    Sub-pool of Sabatini/Lander sgRNA library enriched for control targets.

    Depositor

    Eric Lander, David Sabatini

    Article

    Wang et al Science. 2014 Jan 3;343(6166):80-4. doi:

    Expression

    Mammalian

    Species

    Homo sapiens

    Use

    CRISPR and Lentiviral

    Available since

    Feb. 7, 2014

    Availability

    Academic Institutions and Nonprofits only

24. DNA repair library with 336 sgRNAs

    Pooled Library

    #177664

    Purpose

    CRISPR-interference (CRISPRi) library of 366 sgRNAs targeting 118 genes encoding factors involved in DNA repair and associated processes

    Depositor

    Brittany Adamson

    Article

    Hussmann et al Cell. 2021 Oct 28;184(22):5653-5669.e25.

    Species

    Homo sapiens

    Use

    CRISPR

    Available since

    Nov. 29, 2023

    Availability

    Academic Institutions and Nonprofits only

25. psgRNA Library

    Pooled Library

    #115927

    Purpose

    Genome-wide knockdown of E. coli genes

    Depositor

    David Bikard

    Article

    Cui et al Nat Commun. 2018 May 15;9(1):1912. doi:

    Expression

    Bacterial

    Species

    Escherichia coli

    Use

    CRISPR

    Available since

    June 6, 2019

    Availability

    Academic Institutions and Nonprofits only

26. E.coli_GW-sgRNA_Lib3

    Pooled Library

    #113136

    Purpose

    Genome-wide gRNA library for E. coli, sub3

    Depositor

    Chong Zhang

    Article

    Wang et al Nat Commun. 2018 Jun 26;9(1):2475. doi:

    Expression

    Bacterial

    Available since

    May 14, 2019

    Availability

    Academic Institutions and Nonprofits only

27. E.coli_GW-sgRNA_Lib1

    Pooled Library

    #113134

    Purpose

    Genome-wide gRNA library for E. coli, sub1

    Depositor

    Chong Zhang

    Article

    Wang et al Nat Commun. 2018 Jun 26;9(1):2475. doi:

    Expression

    Bacterial

    Available since

    May 14, 2019

    Availability

    Academic Institutions and Nonprofits only

28. E.coli_GW-sgRNA_Lib4

    Pooled Library

    #113137

    Purpose

    Genome-wide gRNA library for E. coli, sub4

    Depositor

    Chong Zhang

    Article

    Wang et al Nat Commun. 2018 Jun 26;9(1):2475. doi:

    Expression

    Bacterial

    Available since

    May 14, 2019

    Availability

    Academic Institutions and Nonprofits only

29. E.coli_GW-sgRNA_Lib2

    Pooled Library

    #113135

    Purpose

    Genome-wide gRNA library for E. coli, sub2

    Depositor

    Chong Zhang

    Article

    Wang et al Nat Commun. 2018 Jun 26;9(1):2475. doi:

    Expression

    Bacterial

    Available since

    May 14, 2019

    Availability

    Academic Institutions and Nonprofits only

30. E.coli_GW-sgRNA_Lib5

    Pooled Library

    #113138

    Purpose

    Genome-wide gRNA library for E. coli, sub5

    Depositor

    Chong Zhang

    Article

    Guo et al Nucleic Acids Res. 2018 Aug 21;46(14):70

    Expression

    Bacterial

    Available since

    May 14, 2019

    Availability

    Academic Institutions and Nonprofits only

31. hCRISPRa-v2, genome-wide, 10 sgRNAs/gene

    Pooled Library

    #1000000091

    Purpose

    Genome-wide CRISPR gRNA pooled library for activation of human genes

    Depositor

    Jonathan Weissman

    Available since

    Nov. 15, 2016

    Availability

    Academic Institutions and Nonprofits only

32. mCRISPRi-v2, genome-wide, 10 sgRNAs/gene

    Pooled Library

    #1000000092

    Purpose

    Genome-wide CRISPR gRNA pooled library for inhibition of mouse genes

    Depositor

    Jonathan Weissman

    Available since

    Nov. 15, 2016

    Availability

    Academic Institutions and Nonprofits only

33. mCRISPRi-v2, Unassigned (m7), top 5 sgRNAs/gene

    Pooled Library

    #83995

    Purpose

    Mouse CRISPRi Pooled Library targeting unassigned genes

    Depositor

    Jonathan Weissman

    Article

    Horlbeck et al Elife. 2016 Sep 23;5. pii: e19760. doi:

    Available since

    Jan. 12, 2017

    Availability

    Academic Institutions and Nonprofits only

34. mCRISPRa-v2, genome-wide, 10 sgRNAs/gene

    Pooled Library

    #1000000093

    Purpose

    Genome-wide CRISPR gRNA pooled library for activation of mouse genes

    Depositor

    Jonathan Weissman

    Available since

    Nov. 15, 2016

    Availability

    Academic Institutions and Nonprofits only

35. hCRISPRa-v2, Unassigned (h7), top 5 sgRNAs/gene

    Pooled Library

    #83986

    Purpose

    Human CRISPRa Pooled Library targeting unassigned genes

    Depositor

    Jonathan Weissman

    Article

    Horlbeck et al Elife. 2016 Sep 23;5. pii: e19760. doi:

    Available since

    Jan. 12, 2017

    Availability

    Academic Institutions and Nonprofits only

36. mCRISPRa-v2, Unassigned (m7), top 5 sgRNAs/gene

    Pooled Library

    #84004

    Purpose

    Mouse CRISPRa Pooled Library targeting unassigned genes

    Depositor

    Jonathan Weissman

    Article

    Horlbeck et al Elife. 2016 Sep 23;5. pii: e19760. doi:

    Available since

    Jan. 12, 2017

    Availability

    Academic Institutions and Nonprofits only

37. hCRISPRi-v2, Unassigned (h7), top 5 sgRNAs/gene

    Pooled Library

    #83977

    Purpose

    Human CRISPRi Pooled Library targeting unassigned genes

    Depositor

    Jonathan Weissman

    Article

    Horlbeck et al Elife. 2016 Sep 23;5. pii: e19760. doi:

    Available since

    Dec. 14, 2016

    Availability

    Academic Institutions and Nonprofits only

38. Human sgRNA library Brunello in lentiGuide-Puro

    Pooled Library

    #73178

    Purpose

    Human sgRNA library in backbone lentiGuide-Puro targeting 19,114 genes and containing 76,441 unique sgRNAs along with 1000 non-targeting controls

    Depositor

    David Root, John Doench

    Article

    Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

    Has Service

    Lentiviral Prep

    Expression

    Mammalian

    Use

    CRISPR and Lentiviral

    Available since

    Feb. 9, 2016

    Availability

    Academic Institutions and Nonprofits only

39. Mouse sgRNA library Brie in lentiGuide-Puro

    Pooled Library

    #73633

    Purpose

    Mouse sgRNA library in backbone lentiGuide-Puro containing 78,637 unique sgRNAs targeting 19,674 genes along with 1000 non-targeting controls

    Depositor

    David Root, John Doench

    Article

    Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

    Has Service

    Lentiviral Prep

    Expression

    Mammalian

    Use

    CRISPR and Lentiviral

    Available since

    Feb. 25, 2016

    Availability

    Academic Institutions and Nonprofits only

40. hCRISPRi-v2, genome-wide, top 5 sgRNAs/gene

    Pooled Library

    #83969

    Purpose

    Version 2 of the human CRISPRi genome wide library

    Depositor

    Jonathan Weissman

    Article

    Horlbeck et al Elife. 2016 Sep 23;5. pii: e19760. doi:

    Use

    Lentiviral

    Available since

    Nov. 15, 2016

    Availability

    Academic Institutions and Nonprofits only

41. Human GeCKO Lentiviral sgRNA Library v2 (LentiCRISPR)

    Pooled Library

    #1000000048

    Purpose

    CRISPR gRNA knockout pooled library for targeting the human genome

    Depositor

    Feng Zhang

    Available since

    May 8, 2014

    Availability

    Academic Institutions and Nonprofits only

42. hCRISPRa-v2, genome-wide, top 5 sgRNAs/gene

    Pooled Library

    #83978

    Purpose

    Version 2 of the human CRISPRa genome wide library

    Depositor

    Jonathan Weissman

    Article

    Horlbeck et al Elife. 2016 Sep 23;5. pii: e19760. doi:

    Use

    Lentiviral

    Available since

    Nov. 15, 2016

    Availability

    Academic Institutions and Nonprofits only

43. hCRISPRi-v2, Membrane Proteins (h6), top 5 sgRNAs/gene

    Pooled Library

    #83976

    Purpose

    Human CRISPRi Pooled Library targeting membrane proteins

    Depositor

    Jonathan Weissman

    Article

    Horlbeck et al Elife. 2016 Sep 23;5. pii: e19760. doi:

    Available since

    Dec. 14, 2016

    Availability

    Academic Institutions and Nonprofits only

44. mCRISPRa-v2, Membrane Proteins (m6), top 5 sgRNAs/gene

    Pooled Library

    #84003

    Purpose

    Mouse CRISPRa Pooled Library targeting membrane proteins

    Depositor

    Jonathan Weissman

    Article

    Horlbeck et al Elife. 2016 Sep 23;5. pii: e19760. doi:

    Available since

    Jan. 12, 2017

    Availability

    Academic Institutions and Nonprofits only

45. hCRISPRa-v2, Membrane Proteins (h6), top 5 sgRNAs/gene

    Pooled Library

    #83985

    Purpose

    Human CRISPRa Pooled Library targeting membrane proteins

    Depositor

    Jonathan Weissman

    Article

    Horlbeck et al Elife. 2016 Sep 23;5. pii: e19760. doi:

    Available since

    Jan. 12, 2017

    Availability

    Academic Institutions and Nonprofits only

46. Mouse GeCKO Lentiviral sgRNA Library (LentiCRISPR)

    Pooled Library

    #1000000052

    Purpose

    CRISPR gRNA knockout pooled library for targeting the mouse genome

    Depositor

    Feng Zhang

    Available since

    July 23, 2014

    Availability

    Academic Institutions and Nonprofits only

47. Human Metabolic Gene CRISPRa sgRNA library

    Pooled Library

    #187080

    Purpose

    Lentiviral CRISPRa library targeting human metabolic genes for activation of gene expression

    Depositor

    Kivanc Birsoy

    Article

    Unlu et al Mol Cell. 2022 Aug 4;82(15):2832-2843.e7

    Expression

    Mammalian

    Species

    Homo sapiens

    Use

    Lentiviral

    Available since

    Oct. 26, 2022

    Availability

    Academic Institutions and Nonprofits only

48. mCRISPRi-v2, Gene Expression (m5), top 5 sgRNAs/gene

    Pooled Library

    #83993

    Purpose

    Mouse CRISPRi Pooled Library targeting gene expression

    Depositor

    Jonathan Weissman

    Article

    Horlbeck et al Elife. 2016 Sep 23;5. pii: e19760. doi:

    Available since

    Jan. 12, 2017

    Availability

    Academic Institutions and Nonprofits only

49. Human sgRNA library Gattinara in pRDA_118 backbone

    Pooled Library

    #136986

    Purpose

    Expresses sgRNAs targeting human genes

    Depositor

    John Doench

    Article

    DeWeirdt et al Nat Commun. 2020 Feb 6;11(1):752. doi: 1

    Expression

    Mammalian

    Species

    Homo sapiens

    Use

    CRISPR and Lentiviral

    Available since

    Feb. 24, 2020

    Availability

    Academic Institutions and Nonprofits only

50. hCRISPRa-v2, Gene Expression (h5), top 5 sgRNAs/gene

    Pooled Library

    #83984

    Purpose

    Human CRISPRa Pooled Library targeting gene expression

    Depositor

    Jonathan Weissman

    Article

    Horlbeck et al Elife. 2016 Sep 23;5. pii: e19760. doi:

    Available since

    Jan. 12, 2017

    Availability

    Academic Institutions and Nonprofits only