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Showing: 181 - 200 of 277 results

  1. Pan-Druggable Cancer Library

    Pooled Library
    #182133
    Purpose
    All-in-one CRISPR/Cas system with 74 individual elements. 63 elements target cancer-related genes with FDA-approved drug treatments, and 3 elements target key medulloblastoma driver genes.
    Depositor
    Prashant Mali
    Article
    Hu et al Biomaterials. 2022 Jan;280:121276. doi:
    Species
    Homo sapiens
    Use
    CRISPR and Lentiviral
    Available since
    Aug. 26, 2022
    Availability
    Academic Institutions and Nonprofits only

  4. BARBEKO sgRNA library

    Pooled Library
    #174163
    Purpose
    iBARed cytosine Base Editing-mediated gene KnockOut (BARBEKO) sgRNA library; This library leverages CRISPR cytosine base editors for genome-scale knockout screens.
    Depositor
    Wensheng Wei
    Article
    Xu et al Nat Biotechnol. 2021 Jun 21. pii: 10.103
    Expression
    Mammalian
    Species
    Homo sapiens
    Use
    CRISPR and Lentiviral
    Available since
    Aug. 31, 2021
    Availability
    Academic Institutions and Nonprofits only

  6. KSHV Tiling Library

    Pooled Library
    #180272
    Purpose
    sgRNA library tiling entire ~154 kb of the BAC16 Kaposi’s Sarcoma-associated Herpes viral genome. A guide every ~8 bp allows pooled screening of viral genome.
    Depositor
    Britt Glaunsinger
    Article
    Morgens et al PLoS Pathog. 2022 Jan 18;18(1):e1010236.
    Expression
    Mammalian
    Species
    Kaposi’s sarcoma-associated herpes virus
    Use
    Lentiviral
    Available since
    Feb. 11, 2022
    Availability
    Academic Institutions and Nonprofits only

  9. Mouse Cardiac Transcriptional Regulators CRISPR Knockout Library

    Pooled Library
    #138015
    Purpose
    This library can be used to investigate cardiac gene regulation. It targets transcriptional regulators that are expressed in mouse cardiomyocytes. A subset of GATA4 regulated genes are also included.
    Depositor
    William Pu
    Article
    VanDusen et al bioRxiv 2019, 808402v1; doi: https://doi
    Species
    Mus musculus
    Use
    AAV, CRISPR, and Cre/Lox
    Available since
    April 17, 2020
    Availability
    Academic Institutions and Nonprofits only

  10. EFS-mTSG

    Pooled Library
    #113584
    Purpose
    AAV-CRISPR library for pool mutagenesis of top tumor suppressor genes
    Depositor
    Sidi Chen
    Article
    Wang et al Sci Adv. 2018 Feb 28;4(2):eaao5508. doi:
    Expression
    Mammalian
    Use
    AAV, CRISPR, Lentiviral, and Luciferase
    Available since
    July 23, 2019
    Availability
    Academic Institutions and Nonprofits only

  19. TBG-mTSG

    Pooled Library
    #113585
    Purpose
    AAV-CRISPR library for pool mutagenesis of top tumor suppressor genes in mouse liver
    Depositor
    Sidi Chen
    Article
    Wang et al Sci Adv. 2018 Feb 28;4(2):eaao5508. doi:
    Expression
    Mammalian
    Use
    AAV, CRISPR, Lentiviral, and Luciferase
    Available since
    July 23, 2019
    Availability
    Academic Institutions and Nonprofits only
Showing: 181 - 200 of 277 results