We narrowed to 176 results for: lenti

1. hCRISPRi_dual_5_6

   Pooled Library

   #187248

   Purpose

   Ultra-compact, human genome-wide CRISPRi library targeting each gene with a single element encoding a dual sgRNA cassette.

   Depositor

   Jonathan Weissman, Marco Jost

   Article

   Replogle et al eLife. 2022 Dec 28;11:e81856. doi: 10.75

   Species

   Synthetic

   Use

   Lentiviral

   Available since

   Sept. 30, 2022

   Availability

   Academic Institutions and Nonprofits only

2. TBG-mTSG

   Pooled Library

   #113585

   Purpose

   AAV-CRISPR library for pool mutagenesis of top tumor suppressor genes in mouse liver

   Depositor

   Sidi Chen

   Article

   Wang et al Sci Adv. 2018 Feb 28;4(2):eaao5508. doi:

   Expression

   Mammalian

   Use

   AAV, CRISPR, Lentiviral, and Luciferase

   Available since

   July 23, 2019

   Availability

   Academic Institutions and Nonprofits only

3. mTF-CRISPRai

   Pooled Library

   #122131

   Purpose

   Expresses gRNAs for mouse transcription factor-CRISPR activation

   Depositor

   Stanley Qi

   Article

   Liu et al Cell Stem Cell. 2018 Sep 28. pii: S1934-

   Expression

   Mammalian

   Species

   Mus musculus

   Use

   CRISPR and Lentiviral

   Available since

   April 25, 2019

   Availability

   Academic Institutions and Nonprofits only

4. hCRISPRi_dual_3_4

   Pooled Library

   #187247

   Purpose

   Ultra-compact, human genome-wide CRISPRi library targeting each gene with a single element encoding a dual sgRNA cassette.

   Depositor

   Jonathan Weissman, Marco Jost

   Article

   Replogle et al eLife. 2022 Dec 28;11:e81856. doi: 10.75

   Species

   Synthetic

   Use

   Lentiviral

   Available since

   Sept. 30, 2022

   Availability

   Academic Institutions and Nonprofits only

5. Human Genome-wide Intron Tagging Library, Frame 1

   Pooled Library

   #216134

   Purpose

   Library of intron-targeting sgRNAs for pooled tagging of proteins with GFP or other protein tags at their endogenous genomic locus using an intron tagging approach.

   Depositor

   Stefan Kubicek

   Article

   Reicher et al Nat Cell Biol. 2024 May;26(5):745-756. d

   Expression

   Mammalian

   Use

   CRISPR and Lentiviral

   Available since

   April 19, 2024

   Availability

   Academic Institutions and Nonprofits only

6. KSHV Tiling Library

   Pooled Library

   #180272

   Purpose

   sgRNA library tiling entire ~154 kb of the BAC16 Kaposi’s Sarcoma-associated Herpes viral genome. A guide every ~8 bp allows pooled screening of viral genome.

   Depositor

   Britt Glaunsinger

   Article

   Morgens et al PLoS Pathog. 2022 Jan 18;18(1):e1010236.

   Expression

   Mammalian

   Species

   Kaposi’s sarcoma-associated herpes virus

   Use

   Lentiviral

   Available since

   Feb. 11, 2022

   Availability

   Academic Institutions and Nonprofits only

7. EFS-mTSG

   Pooled Library

   #113584

   Purpose

   AAV-CRISPR library for pool mutagenesis of top tumor suppressor genes

   Depositor

   Sidi Chen

   Article

   Wang et al Sci Adv. 2018 Feb 28;4(2):eaao5508. doi:

   Expression

   Mammalian

   Use

   AAV, CRISPR, Lentiviral, and Luciferase

   Available since

   July 23, 2019

   Availability

   Academic Institutions and Nonprofits only

8. hCRISPRa_dual_3_4

   Pooled Library

   #187250

   Purpose

   Ultra-compact, human genome-wide CRISPRi library targeting each gene with a single element encoding a dual sgRNA cassette.

   Depositor

   Jonathan Weissman, Marco Jost

   Article

   Replogle et al eLife. 2022 Dec 28;11:e81856. doi: 10.75

   Species

   Synthetic

   Use

   Lentiviral

   Available since

   Sept. 30, 2022

   Availability

   Academic Institutions and Nonprofits only

9. hCRISPRa_dual_5_6

   Pooled Library

   #187251

   Purpose

   Ultra-compact, human genome-wide CRISPRi library targeting each gene with a single element encoding a dual sgRNA cassette.

   Depositor

   Jonathan Weissman, Marco Jost

   Article

   Replogle et al eLife. 2022 Dec 28;11:e81856. doi: 10.75

   Species

   Synthetic

   Use

   Lentiviral

   Available since

   Sept. 30, 2022

   Availability

   Academic Institutions and Nonprofits only

10. mU6-CR1-CRISPRiv2_hU6-CR3-NT-ctrl-guide_EF1a-PuroR-T2A-BFP

    Pooled Library

    #197348

    Purpose

    To allow for genome-wide genetic modifier screening, the library has a second fixed non-targeting control guide.

    Depositor

    Jonathan Weissman, Rebecca Voorhees

    Article

    Guna et al BMC Genomics. 2023 Oct 30;24(1):651. doi

    Species

    Homo sapiens

    Use

    Lentiviral

    Available since

    May 25, 2023

    Availability

    Academic Institutions and Nonprofits only

11. mU6-CR1-CRISPRiv2_hU6-CR3-EMC2-guide_EF1a-PuroR-T2A-BFP

    Pooled Library

    #197349

    Purpose

    To allow for genome-wide genetic modifier screening, the library has a second fixed guide targeting EMC2.

    Depositor

    Jonathan Weissman, Rebecca Voorhees

    Article

    Guna et al BMC Genomics. 2023 Oct 30;24(1):651. doi

    Species

    Homo sapiens

    Use

    Lentiviral

    Available since

    May 25, 2023

    Availability

    Academic Institutions and Nonprofits only

12. ACER

    Pooled Library

    #226117

    Purpose

    The Advanced Catalogue of Epigenetic Regulators (ACER) library allows scientists to study how different epigenetic proteins influence gene activity and contribute to diseases.

    Depositor

    Rui Lu

    Article

    Zhou et al Blood. 2024 Aug 16:blood.2023023644. doi

    Expression

    Mammalian

    Species

    Homo sapiens

    Use

    CRISPR and Lentiviral

    Available since

    Oct. 29, 2024

    Availability

    Academic Institutions and Nonprofits only

13. MinLibCas9

    Pooled Library

    #164896

    Purpose

    Human genome-wide CRISPR-Cas9 gRNA library, optimised by mining existing large-scale screening datasets, which provides a >60% reduction in size while preserving key information content

    Depositor

    Mathew Garnett

    Article

    Gonçalves et al Genome Biol. 2021 Jan 21;22(1):40. doi:

    Expression

    Mammalian

    Species

    Homo sapiens

    Use

    CRISPR and Lentiviral

    Available since

    May 20, 2021

    Availability

    Academic Institutions and Nonprofits only

14. Human DNA Binding Domain-Focused CRISPR Knockout Library

    Pooled Library

    #123334

    Purpose

    Expresses gRNA targeting the DNA binding domain of human transcription factors.

    Depositor

    Christopher Vakoc

    Article

    Huang et al Genes Dev. 2018 Jul 1;32(13-14):915-928.

    Expression

    Mammalian

    Species

    Homo sapiens

    Use

    CRISPR and Lentiviral

    Available since

    May 2, 2019

    Availability

    Academic Institutions and Nonprofits only

15. DNA repair library with 1,513 sgRNAs

    Pooled Library

    #177670

    Purpose

    CRISPR-interference (CRISPRi) library designed to target 476 genes involved in DNA repair and associated processes. It contains 1,513 sgRNAs and 60 non-targeting control sgRNAs.

    Depositor

    Brittany Adamson

    Article

    Chen et al Cell. 2021 Oct 28;184(22):5635-5652.e29.

    Expression

    Mammalian

    Species

    Homo sapiens

    Use

    CRISPR and Lentiviral

    Available since

    July 11, 2023

    Availability

    Academic Institutions and Nonprofits only

16. Human SLC overexpression library

    Pooled Library

    #213694

    Purpose

    Inducible barcoded library with 467 codon-optimized cDNAs with UMIs to test the impact of SLC transporters on biological processes.

    Depositor

    Giulio Superti-Furga, RESOLUTE Consortium

    Article

    Wolf et al Cell Chem Biol. 2024 Dec 24:S2451-9456(2

    Expression

    Mammalian

    Species

    Homo sapiens

    Use

    Lentiviral

    Available since

    Aug. 30, 2024

    Availability

    Academic Institutions and Nonprofits only

17. Human Genome-wide Intron Tagging Library, Frame 0

    Pooled Library

    #216133

    Purpose

    Library of intron-targeting sgRNAs for pooled tagging of proteins with GFP or other protein tags at their endogenous genomic locus using an intron tagging approach.

    Depositor

    Stefan Kubicek

    Article

    Reicher et al Nat Cell Biol. 2024 May;26(5):745-756. d

    Expression

    Mammalian

    Use

    CRISPR and Lentiviral

    Available since

    April 19, 2024

    Availability

    Academic Institutions and Nonprofits only

18. Compact mismatched sgRNA library for gene titration (human essential genes, CRISPRi)

    Pooled Library

    #136479

    Purpose

    Expresses gRNAs for gene titration of ~2400 human genes using CRISPRi

    Depositor

    Jonathan Weissman

    Article

    Jost et al Nat Biotechnol. 2020 Jan 13. pii: 10.103

    Expression

    Mammalian

    Species

    Homo sapiens

    Use

    CRISPR and Lentiviral

    Available since

    Feb. 25, 2020

    Availability

    Academic Institutions and Nonprofits only

19. Large-scale mismatched sgRNA library for gene titration (human essential genes, CRISPRi)

    Pooled Library

    #136478

    Purpose

    Expresses gRNAs for gene titration of ~2400 human genes using CRISPRi

    Depositor

    Jonathan Weissman

    Article

    Jost et al Nat Biotechnol. 2020 Jan 13. pii: 10.103

    Expression

    Mammalian

    Species

    Homo sapiens

    Use

    CRISPR and Lentiviral

    Available since

    Feb. 25, 2020

    Availability

    Academic Institutions and Nonprofits only

20. UMI-sgRNA-TF

    Pooled Library

    #234819

    Purpose

    Unique molecular identifiers-linked sgRNA library targeting transcription factors (TFs) in mice.

    Depositor

    Benjamin Ebert

    Article

    Loke et al Blood. 2025 Jun 10:blood.2024028033. doi

    Expression

    Mammalian

    Species

    Mus musculus

    Use

    CRISPR and Lentiviral

    Available since

    June 11, 2025

    Availability

    Academic Institutions and Nonprofits only