We narrowed to 276 results for: cas

1. Mouse CRISPRa sgRNA library Caprano in backbone XPR_502 (P65 HSF), Set B

   Pooled Library

   #92384

   Purpose

   CRISPRa

   Depositor

   David Root, John Doench

   Article

   Sanson et al Nat Commun. 2018 Dec 21;9(1):5416. doi:

   Expression

   Mammalian

   Use

   CRISPR and Lentiviral

   Available since

   July 13, 2018

   Availability

   Academic Institutions and Nonprofits only

2. Self-targeting epegRNA library, Tiled edits (lRM001)

   Pooled Library

   #227708

   Purpose

   CRISPR guide RNA library for prime editing

   Depositor

   Brittany Adamson

   Article

   Cirincione et al Nat Methods. 2024 Nov 19. doi: 10.1038/s

   Expression

   Mammalian

   Use

   Lentiviral

   Available since

   Jan. 23, 2025

   Availability

   Academic Institutions and Nonprofits only

3. mU6-CR1-CRISPRiv2_hU6-CR3-EMC2-guide_EF1a-PuroR-T2A-BFP

   Pooled Library

   #197349

   Purpose

   To allow for genome-wide genetic modifier screening, the library has a second fixed guide targeting EMC2.

   Depositor

   Jonathan Weissman, Rebecca Voorhees

   Article

   Guna et al BMC Genomics. 2023 Oct 30;24(1):651. doi

   Species

   Homo sapiens

   Use

   Lentiviral

   Available since

   May 25, 2023

   Availability

   Academic Institutions and Nonprofits only

4. CHyMErA Exon-deletion hgRNA Library

   Pooled Library

   #155200

   Purpose

   Hybrid guide RNA library targeting human alternative cassette exons for deletion and disruption

   Depositor

   Benjamin Blencowe, Jason Moffat

   Article

   Gonatopoulos-Pournatzis et al Nat Biotechnol. 2020 May;38(5):638-648.

   Expression

   Mammalian

   Use

   CRISPR and Lentiviral

   Available since

   Sept. 2, 2020

   Availability

   Academic Institutions and Nonprofits only

5. Mini-human AsCpf1-based human genome-wide knockout library

   Pooled Library

   #130630

   Purpose

   Expresses crRNAs for genome-wide knockout pooled library screening

   Depositor

   Giulio Draetta

   Article

   Liu et al Nat Commun. 2019 Jul 17;10(1):3144. doi:

   Expression

   Mammalian

   Species

   Homo sapiens

   Use

   CRISPR and Lentiviral

   Available since

   Sept. 9, 2019

   Availability

   Academic Institutions and Nonprofits only

6. Inzolia library in pRDA_550

   Pooled Library

   #209552

   Purpose

   The human, genome-wide, CRISPR knockout enAsCas12a gRNA library targets single genes and paralog pairs, triples, and quads with arrays of 4 gRNAs.

   Depositor

   John Doench

   Article

   Esmaeili Anvar et al Nat Commun. 2024 Apr 27;15(1):3577. doi:

   Use

   CRISPR and Lentiviral

   Available since

   Dec. 5, 2023

   Availability

   Academic Institutions and Nonprofits only

7. Inzolia library in pRDA_052

   Pooled Library

   #209551

   Purpose

   The human, genome-wide, CRISPR knockout enAsCas12a gRNA library targets single genes and paralog pairs, triples, and quads with arrays of 4 gRNAs.

   Depositor

   John Doench

   Article

   Esmaeili Anvar et al Nat Commun. 2024 Apr 27;15(1):3577. doi:

   Use

   CRISPR and Lentiviral

   Available since

   Dec. 5, 2023

   Availability

   Academic Institutions and Nonprofits only

8. Human Kinase Domain-Focused CRISPR Knockout Library

   Pooled Library

   #117725

   Purpose

   gRNAs targeting the kinase domain of human protein kinases

   Depositor

   Christopher Vakoc

   Article

   Tarumoto et al Mol Cell. 2018 Feb 28. pii: S1097-2765(1

   Expression

   Mammalian

   Species

   Homo sapiens

   Use

   CRISPR and Lentiviral

   Available since

   Jan. 4, 2019

   Availability

   Academic Institutions and Nonprofits only

9. hCRISPRa-v2, Kinases, Phosphatases, and Drug Targets (h1), top 5 sgRNAs/gene

   Pooled Library

   #83980

   Purpose

   Human CRISPRa Pooled Library tartgeting kinsases, phosphatases and Drug Targets

   Depositor

   Jonathan Weissman

   Article

   Horlbeck et al Elife. 2016 Sep 23;5. pii: e19760. doi:

   Available since

   Jan. 12, 2017

   Availability

   Academic Institutions and Nonprofits only

10. DNA repair library with 1,573 sgRNAs

    Pooled Library

    #177663

    Purpose

    CRISPR-interference (CRISPRi) library of 1,573 sgRNAs targeting 476 genes encoding factors involved in DNA repair and associated processes

    Depositor

    Brittany Adamson

    Article

    Hussmann et al Cell. 2021 Oct 28;184(22):5653-5669.e25.

    Species

    Homo sapiens

    Use

    CRISPR

    Available since

    July 11, 2023

    Availability

    Academic Institutions and Nonprofits only

11. Humagne Set C

    Pooled Library

    #172650

    Purpose

    Set C contains best-ranked guides 1 and 4.

    Depositor

    David Root, John Doench

    Article

    DeWeirdt et al Nat Biotechnol. 2020 Jul 13. pii: 10.103

    Expression

    Mammalian

    Available since

    Nov. 10, 2021

    Availability

    Academic Institutions and Nonprofits only

12. Mouse sphingolipid metabolism knockout library

    Pooled Library

    #206249

    Purpose

    The sphingolipid metabolism library targets 82 mouse genes in the de novo ceramide and downstream sphingolipid metabolism pathways.

    Depositor

    Kivanc Birsoy

    Article

    Soula et al Nature. 2024 Aug 7. doi: 10.1038/s41586-

    Use

    CRISPR and Lentiviral

    Available since

    Aug. 29, 2024

    Availability

    Academic Institutions and Nonprofits only

13. pC004 - PFS library in Beta-lactamase gene Target Plasmid

    Pooled Library

    #79153

    Purpose

    PFS library inserted at the 5' of the Beta-lactamase gene for screening PFS preference

    Depositor

    Feng Zhang

    Article

    Abudayyeh et al Science. 2016 Jun 2. pii: aaf5573.

    Available since

    Oct. 26, 2017

    Availability

    Academic Institutions and Nonprofits only

14. mCRISPRi-v2, Kinases, Phosphatases, and Drug Targets (m1), top 5 sgRNAs/gene

    Pooled Library

    #83989

    Purpose

    Mouse CRISPRi Pooled Library tartgeting kinsases, phosphatases and Drug Targets

    Depositor

    Jonathan Weissman

    Article

    Horlbeck et al Elife. 2016 Sep 23;5. pii: e19760. doi:

    Available since

    Jan. 12, 2017

    Availability

    Academic Institutions and Nonprofits only

15. hCRISPRi-v2, Kinases, Phosphatases, and Drug Targets (h1), top 5 sgRNAs/gene

    Pooled Library

    #83971

    Purpose

    Human CRISPRi Pooled Library tartgeting kinsases, phosphatases and Drug Targets

    Depositor

    Jonathan Weissman

    Article

    Horlbeck et al Elife. 2016 Sep 23;5. pii: e19760. doi:

    Available since

    Dec. 14, 2016

    Availability

    Academic Institutions and Nonprofits only

16. Humagne Set D

    Pooled Library

    #172651

    Purpose

    Set D contains best-ranked guides 2 and 3.

    Depositor

    David Root, John Doench

    Article

    DeWeirdt et al Nat Biotechnol. 2020 Jul 13. pii: 10.103

    Expression

    Mammalian

    Available since

    Nov. 10, 2021

    Availability

    Academic Institutions and Nonprofits only

17. mCRISPRa-v2, Kinases, Phosphatases, and Drug Targets (m1), top 5 sgRNAs/gene

    Pooled Library

    #83998

    Purpose

    Mouse CRISPRi Pooled Library tartgeting kinsases, phosphatases and Drug Targets

    Depositor

    Jonathan Weissman

    Article

    Horlbeck et al Elife. 2016 Sep 23;5. pii: e19760. doi:

    Available since

    Jan. 12, 2017

    Availability

    Academic Institutions and Nonprofits only

18. Lourido Toxoplasma CRISPR Library V1

    Pooled Library

    #80636

    Purpose

    Plasmid sgRNA library containing ten guides against each of the 8,158 predicted Toxoplasma gondii protein coding genes.

    Depositor

    Sebastian Lourido

    Article

    Sidik et al Cell. 2016 Sep 8;166(6):1423-1435.e12. d

    Available since

    Sept. 19, 2016

    Availability

    Academic Institutions and Nonprofits only

19. Human Transporter Knockout Library with UMIs

    Pooled Library

    #221409

    Purpose

    gRNA library to test the impact of transporters on biological processes

    Depositor

    RESOLUTE Consortium, Giulio Superti-Furga

    Article

    Wolf et al Cell Chem Biol. 2024 Dec 24:S2451-9456(2

    Species

    Homo sapiens

    Use

    CRISPR and Lentiviral

    Available since

    Sept. 13, 2024

    Availability

    Academic Institutions and Nonprofits only

20. EFS-mTSG

    Pooled Library

    #113584

    Purpose

    AAV-CRISPR library for pool mutagenesis of top tumor suppressor genes

    Depositor

    Sidi Chen

    Article

    Wang et al Sci Adv. 2018 Feb 28;4(2):eaao5508. doi:

    Expression

    Mammalian

    Use

    AAV, CRISPR, Lentiviral, and Luciferase

    Available since

    July 23, 2019

    Availability

    Academic Institutions and Nonprofits only