We narrowed to 76 results for: TOR

1. mTORC1 Focused library

   Pooled Library

   #164084

   Purpose

   Lentiviral CRISPR library targets human mTORC1 signaling pathway

   Depositor

   David Sabatini

   Article

   Condon et al Proc Natl Acad Sci U S A. 2021 Jan 26;11

   Expression

   Mammalian

   Species

   Homo sapiens

   Use

   CRISPR and Lentiviral

   Available since

   Jan. 11, 2021

   Availability

   Academic Institutions and Nonprofits only

2. Mouse Chromatin Regulator Library

   Pooled Library

   #200011

   Purpose

   CRISPR KO library targeting a comprehensive set of genes with annotated function as chromatin regulators.

   Depositor

   Bradley Bernstein, Gabriel Griffin, Robert Manguso

   Article

   Griffin et al Nature. 2021 Jul;595(7866):309-314. doi:

   Expression

   Mammalian

   Use

   CRISPR and Lentiviral

   Available since

   Dec. 15, 2023

   Availability

   Academic Institutions and Nonprofits only

3. Toronto KnockOut Library (TKOv1)

   Pooled Library

   #1000000069

   Purpose

   CRISPR gRNA knockout pooled library for targeting the human genome

   Depositor

   Stephane Angers, Jason Moffat

   Available since

   Jan. 28, 2016

   Availability

   Academic Institutions and Nonprofits only

4. Toronto KnockOut version 3 library (TKOv3)

   Pooled Library

   #90294

   Purpose

   Optimized library offering improved accuracy, efficiency, and scalability for CRISPR screens compared to TKOv1

   Depositor

   Jason Moffat

   Article

   Hart et al G3 (Bethesda). 2017 Aug 7;7(8):2719-2727

   Available since

   May 5, 2017

   Availability

   Academic Institutions and Nonprofits only

5. Mouse Toronto KnockOut (mTKO) CRISPR Library - pLCKO2

   Pooled Library

   #159393

   Purpose

   Mouse lentiviral genome-wide CRISPR library

   Depositor

   Jason Moffat

   Article

   Lawson et al Nature. 2020 Oct;586(7827):120-126. doi:

   Expression

   Mammalian

   Species

   Mus musculus

   Use

   CRISPR and Lentiviral

   Available since

   Nov. 9, 2020

   Availability

   Academic Institutions and Nonprofits only

6. Mouse Toronto KnockOut (mTKO) CRISPR Library - lentiCRISPRv2

   Pooled Library

   #159392

   Purpose

   Mouse lentiviral genome-wide CRISPR library

   Depositor

   Jason Moffat

   Article

   Lawson et al Nature. 2020 Oct;586(7827):120-126. doi:

   Expression

   Mammalian

   Species

   Mus musculus

   Use

   CRISPR and Lentiviral

   Available since

   Nov. 9, 2020

   Availability

   Academic Institutions and Nonprofits only

7. Mouse Cardiac Transcriptional Regulators CRISPR Knockout Library

   Pooled Library

   #138015

   Purpose

   This library can be used to investigate cardiac gene regulation. It targets transcriptional regulators that are expressed in mouse cardiomyocytes. A subset of GATA4 regulated genes are also included.

   Depositor

   William Pu

   Article

   VanDusen et al bioRxiv 2019, 808402v1; doi: https://doi

   Species

   Mus musculus

   Use

   AAV, CRISPR, and Cre/Lox

   Available since

   April 17, 2020

   Availability

   Academic Institutions and Nonprofits only

8. SARS-CoV-2 Spike (S) Receptor Binding Domain (RBD) library 1

   Pooled Library

   #168776

   Purpose

   Pooled library expressing barcoded SARS-CoV-2 RNA Binding Domain mutations

   Depositor

   Timothy Whitehead

   Article

   Francino-Urdaniz et al Cell Rep. 2021 Aug 31;36(9):109627. doi:

   Expression

   Yeast

   Species

   Sars-cov-2

   Available since

   Sept. 13, 2021

   Availability

   Academic Institutions and Nonprofits only

9. SARS-CoV-2 Spike (S) Receptor Binding Domain (RBD) library 2

   Pooled Library

   #168777

   Purpose

   Pooled library expressing barcoded SARS-CoV-2 RNA Binding Domain mutations

   Depositor

   Timothy Whitehead

   Article

   Francino-Urdaniz et al Cell Rep. 2021 Aug 31;36(9):109627. doi:

   Expression

   Yeast

   Species

   Sars-cov-2

   Available since

   Sept. 13, 2021

   Availability

   Academic Institutions and Nonprofits only

10. SARS-CoV-2 Spike (S) Receptor Binding Domain (RBD) library N501Y Tile 2 (positions 437-527)

    Pooled Library

    #174296

    Purpose

    This library contains mutations to SARS-CoV-2 Spike RBD N501Y variant in which all surface exposed residues on S RBD (Tile 2, positions 437-527) were mutated to every other amino acid.

    Depositor

    Timothy Whitehead

    Article

    Francino-Urdaniz et al Cell Rep. 2021 Aug 31;36(9):109627. doi:

    Expression

    Yeast

    Available since

    Sept. 13, 2021

    Availability

    Academic Institutions and Nonprofits only

11. SARS-CoV-2 Spike (S) Receptor Binding Domain (RBD) library N501Y Tile 1 (positions 333-436)

    Pooled Library

    #174295

    Purpose

    This library contains mutations to SARS-CoV-2 Spike RBD N501Y variant in which all surface exposed residues on S RBD (Tile 1, positions 333-436) were mutated to every other amino acid.

    Depositor

    Timothy Whitehead

    Article

    Francino-Urdaniz et al Cell Rep. 2021 Aug 31;36(9):109627. doi:

    Expression

    Yeast

    Available since

    Sept. 13, 2021

    Availability

    Academic Institutions and Nonprofits only

12. SARS-CoV-2 Spike (S) Receptor Binding Domain (RBD) library E484K Tile 2 (positions 437-527)

    Pooled Library

    #174294

    Purpose

    This library contains mutations to SARS-CoV-2 Spike RBD E484K variant in which all surface exposed residues on S RBD (Tile 2, positions 437-527) were mutated to every other amino acid.

    Depositor

    Timothy Whitehead

    Article

    Francino-Urdaniz et al Cell Rep. 2021 Aug 31;36(9):109627. doi:

    Expression

    Yeast

    Available since

    Sept. 13, 2021

    Availability

    Academic Institutions and Nonprofits only

13. SARS-CoV-2 Spike (S) Receptor Binding Domain (RBD) library E484K Tile 1 (positions 333-436)

    Pooled Library

    #174293

    Purpose

    This library contains mutations to SARS-CoV-2 Spike RBD E484K variant in which all surface exposed residues on S RBD (Tile 1, positions 333-436) were mutated to every other amino acid.

    Depositor

    Timothy Whitehead

    Article

    Francino-Urdaniz et al Cell Rep. 2021 Aug 31;36(9):109627. doi:

    Expression

    Yeast

    Available since

    Sept. 13, 2021

    Availability

    Academic Institutions and Nonprofits only

14. STICR_Index1

    Pooled Library

    #186334

    Purpose

    High Complexity Lentiviral Barcode Library

    Depositor

    Tomasz Nowakowski

    Article

    Delgado et al Nature. 2021 Dec 15. pii: 10.1038/s41586

    Expression

    Mammalian

    Species

    Synthetic

    Use

    Lentiviral

    Available since

    Sept. 12, 2022

    Availability

    Academic Institutions and Nonprofits only

15. STICR_IndexE

    Pooled Library

    #180483

    Purpose

    High Complexity Lentiviral Barcode Library

    Depositor

    Tomasz Nowakowski

    Article

    Delgado et al Nature. 2021 Dec 15. pii: 10.1038/s41586

    Expression

    Mammalian

    Species

    Synthetic

    Use

    Lentiviral

    Available since

    Sept. 12, 2022

    Availability

    Academic Institutions and Nonprofits only

16. STICR_Index3

    Pooled Library

    #186335

    Purpose

    High Complexity Lentiviral Barcode Library

    Depositor

    Tomasz Nowakowski

    Article

    Delgado et al Nature. 2021 Dec 15. pii: 10.1038/s41586

    Expression

    Mammalian

    Species

    Synthetic

    Use

    Lentiviral

    Available since

    Sept. 12, 2022

    Availability

    Academic Institutions and Nonprofits only

17. Human DNA Binding Domain-Focused CRISPR Knockout Library

    Pooled Library

    #123334

    Purpose

    Expresses gRNA targeting the DNA binding domain of human transcription factors.

    Depositor

    Christopher Vakoc

    Article

    Huang et al Genes Dev. 2018 Jul 1;32(13-14):915-928.

    Expression

    Mammalian

    Species

    Homo sapiens

    Use

    CRISPR and Lentiviral

    Available since

    May 2, 2019

    Availability

    Academic Institutions and Nonprofits only

18. lentiCRISPRv2_ISG

    Pooled Library

    #125753

    Purpose

    Expresses gRNAs targeting human Interferon-Stimulated Genes

    Depositor

    Molly OhAinle, Michael Emerman

    Article

    Roesch et al Retrovirology. 2018 Mar 20;15(1):26. doi

    Expression

    Mammalian

    Species

    Homo sapiens

    Use

    CRISPR and Lentiviral

    Available since

    May 7, 2020

    Availability

    Academic Institutions and Nonprofits only

19. Lenti-human-UBDUB-gRNA-puromycin-IRES-CFP

    Pooled Library

    #171531

    Purpose

    Pooled gRNA library against human ubiquitination and de-ubiquitination complex genes (UBDUB)

    Depositor

    Chunliang Li

    Article

    Wright et al Proc Natl Acad Sci U S A. 2023 Apr 18;12

    Expression

    Mammalian

    Species

    Homo sapiens

    Use

    Lentiviral

    Available since

    June 22, 2021

    Availability

    Academic Institutions and Nonprofits only

20. RNA-binding protein pooled CRISPR knockout library

    Pooled Library

    #141438

    Purpose

    CRISPR knockout library targets RBPs with 10 sgRNAs/gene

    Depositor

    Eugene Yeo

    Article

    Wheeler et al Nat Methods. 2020 May 11. pii: 10.1038/s

    Expression

    Mammalian

    Use

    CRISPR and Lentiviral

    Available since

    May 28, 2020

    Availability

    Academic Institutions and Nonprofits only