We narrowed to 73,923 results for: LAS

1. TRCN0000338401

   Plasmid

   #78157

   Purpose

   shXPO1 targeting CDS

   Depositor

   William Hahn

   Article

   Hong et al Nat Commun. 2016 Jun 22;7:11987. doi: 10

   Insert

   XPO1 (XPO1 Human)
   

   Use

   Lentiviral and RNAi

   Tags

   Expression

   Mutation

   Promoter

   hU6

   Available since

   June 22, 2016

   Availability

   Academic Institutions and Nonprofits only

2. 8024 GFP_Kras_G12C_2A_puro

   Plasmid

   #64373

   Purpose

   This a retroviral expression plasmid expressing GFP tagged G12C mutant Kras 2A oncogene along with puro resistance gene

   Depositor

   Georgios Stathopoulos

   Article

   Agalioti et al Nat Commun. 2017 May 16;8:15205. doi: 10

   Insert

   mouse Kras2A (Kras Mouse)
   

   Use

   Retroviral

   Tags

   GFP

   Expression

   Mutation

   changed glycine 12 to cysteine

   Promoter

   Available since

   July 3, 2017

   Availability

   Academic Institutions and Nonprofits only

   

   Enlarge

3. 8027_GFP-KrasG12C_2B_puro

   Plasmid

   #64372

   Purpose

   This a retroviral expression plasmid expressing GFP tagged G12C mutant Kras 2B oncogene along with puro resistance gene

   Depositor

   Georgios Stathopoulos

   Article

   Agalioti et al Nat Commun. 2017 May 16;8:15205. doi: 10

   Insert

   mouse Kras2B (Kras Mouse)
   

   Use

   Retroviral

   Tags

   GFP

   Expression

   Mutation

   changed glycine 12 to cysteine

   Promoter

   Available since

   July 3, 2017

   Availability

   Academic Institutions and Nonprofits only

   

   Enlarge

4. pLV-SFFV-PIK3CA H1047R-WPRE-UbC-Emerald

   Plasmid

   #203798

   Purpose

   Lentiviral vector expressing human PIK3CA H1047R under the spleen focus-forming virus (SFFV) promoter and Emerald under the Ubiquitin C (UbC) promoter

   Depositor

   Richard Eva, Bart Nieuwenhuis

   Article

   Nieuwenhuis et al EMBO Mol Med. 2020 Aug 7;12(8):e11674. d

   Inserts

   PIK3CA (PIK3CA Human)
   Emerald
   

   Use

   Lentiviral

   Tags

   Expression

   Mammalian

   Mutation

   H1047R

   Promoter

   Available since

   July 21, 2023

   Availability

   Academic Institutions and Nonprofits only

   

   Enlarge

5. 8798 GFP-KrasG12C_2B_hygro

   Plasmid

   #64376

   Purpose

   This a retroviral expression plasmid expressing GFP tagged G12C mutant Kras 2B oncogene along with hygro resistance gene

   Depositor

   Georgios Stathopoulos

   Article

   Agalioti et al Nat Commun. 2017 May 16;8:15205. doi: 10

   Insert

   mouse Kras2B (Kras Mouse)
   

   Use

   Retroviral

   Tags

   GFP

   Expression

   Mutation

   changed glycine 12 to cysteine

   Promoter

   Available since

   July 3, 2017

   Availability

   Academic Institutions and Nonprofits only

   

   Enlarge

6. TRCN0000338399

   Plasmid

   #78156

   Purpose

   shXPO1 targeting CDS

   Depositor

   William Hahn

   Article

   Hong et al Nat Commun. 2016 Jun 22;7:11987. doi: 10

   Insert

   XPO1 (XPO1 Human)
   

   Use

   Lentiviral and RNAi

   Tags

   Expression

   Mutation

   Promoter

   hU6 and hU6

   Available since

   June 22, 2016

   Availability

   Academic Institutions and Nonprofits only

7. 8047_GFP-Kras2B_ires_puro

   Plasmid

   #64371

   Purpose

   This a retroviral expression plasmid expressing GFP tagged wild type Kras 2B oncogene along with puro resistance gene

   Depositor

   Georgios Stathopoulos

   Article

   Agalioti et al Nat Commun. 2017 May 16;8:15205. doi: 10

   Insert

   mouse Kras2B (Kras Mouse)
   

   Use

   Retroviral

   Tags

   GFP

   Expression

   Mutation

   none

   Promoter

   Available since

   July 3, 2017

   Availability

   Academic Institutions and Nonprofits only

   

   Enlarge

8. pLIB_3xFlag-His-PLpro (nsp3) (SARS-CoV-2)

   Plasmid

   #169194

   Purpose

   Baculoviral transfer vector to express SARS-CoV-2 papain-like protease domain (nsp3) in insect cells

   Depositor

   John Diffley

   Article

   Lim et al Biochem J. 2021 Jul 16;478(13):2517-2531

   Insert

   3xFlag-His6-PLpro (ORF1ab Synthetic, SARS-CoV-2)
   

   Use

   Tags

   3xFlag-His6

   Expression

   Insect

   Mutation

   Codon optimised for insect cells (Spodoptera frug…

   Promoter

   Polyhedrin

   Available since

   July 6, 2021

   Availability

   Academic Institutions and Nonprofits only

   

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9. TRCN0000297275

   Plasmid

   #78152

   Purpose

   shCDK4 targeting 3UTR

   Depositor

   William Hahn

   Article

   Hong et al Nat Commun. 2016 Jun 22;7:11987. doi: 10

   Insert

   CDK4 (CDK4 Human)
   

   Use

   RNAi

   Tags

   Expression

   Mutation

   Promoter

   hU6

   Available since

   June 22, 2016

   Availability

   Academic Institutions and Nonprofits only

10. TRCN0000279887

    Plasmid

    #78153

    Purpose

    shCDK4 targeting CDS

    Depositor

    William Hahn

    Article

    Hong et al Nat Commun. 2016 Jun 22;7:11987. doi: 10

    Insert

    CDK4 (CDK4 Human)
    

    Use

    Lentiviral and RNAi

    Tags

    Expression

    Mutation

    Promoter

    hU6 and hU6

    Available since

    June 22, 2016

    Availability

    Academic Institutions and Nonprofits only

11. TRCN0000279952

    Plasmid

    #78155

    Purpose

    shCDK4 targeting 3UTR

    Depositor

    William Hahn

    Article

    Hong et al Nat Commun. 2016 Jun 22;7:11987. doi: 10

    Insert

    CDK4 (CDK4 Human)
    

    Use

    Lentiviral and RNAi

    Tags

    Expression

    Mutation

    Promoter

    hU6 and hU6

    Available since

    June 22, 2016

    Availability

    Academic Institutions and Nonprofits only

12. TRCN0000279953

    Plasmid

    #78154

    Purpose

    shCDK4 targeting CDS

    Depositor

    William Hahn

    Article

    Hong et al Nat Commun. 2016 Jun 22;7:11987. doi: 10

    Insert

    CDK4 (CDK4 Human)
    

    Use

    Lentiviral and RNAi

    Tags

    Expression

    Mutation

    Promoter

    hU6 and hU6

    Available since

    June 22, 2016

    Availability

    Academic Institutions and Nonprofits only

13. pGL4.23-hs737

    Plasmid

    #222472

    Purpose

    Luciferase vector containing the hs737 enhancer sequence (reference sequence).

    Depositor

    Tychele Turner

    Article

    Padhi et al Hum Genomics. 2021 Jul 13;15(1):44. doi:

    Insert

    hs737 enhancer (reference sequence) (LOC110120928 Human)
    

    Use

    Luciferase

    Tags

    Expression

    Mammalian

    Mutation

    Promoter

    Available since

    Aug. 23, 2024

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

14. pcDNA3.1_ZKSCAN1_Tau10-12K317M

    Plasmid

    #194164

    Purpose

    Insert contains intronic ZKSCAN1 Alu repeat elements flanked by tau cDNA exons 10-12 with FTLD-Tau K317M mutation. Expresses the tau circRNA 12-->10 K317M with 3X flag tag in exon 10.

    Depositor

    Stefan Stamm

    Article

    Welden et al Nucleic Acids Res. 2022 Dec 9;50(22):129

    Insert

    Microtubule-associated protein tau 10-12 WT (MAPT Human)
    

    Use

    Tags

    3X Flag

    Expression

    Mammalian

    Mutation

    Changed Lysine 317 to Methionine

    Promoter

    Available since

    Jan. 12, 2023

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

15. Human Transporter Knockout library

    Pooled Library

    #213695

    Purpose

    Next generation transporter-focused CRISPR/Cas9 library targeting transmembrane transporters to test the impact of transporters on biological processes.

    Depositor

    Giulio Superti-Furga, RESOLUTE Consortium

    Article

    Ferdigg et al Life Sci Alliance. 2024 Nov 22;8(2):e202

    Species

    Homo sapiens

    Use

    CRISPR and Lentiviral

    Available since

    Sept. 13, 2024

    Availability

    Academic Institutions and Nonprofits only

16. Human Genome-Wide Reduced Double-gRNA library

    Pooled Library

    #137999

    Purpose

    This gRNA library targets the human coding genome, aimed to reduce the scale of genome-wide perturbation screens up to fivefold compared to conventional methods, without sacrificing performance.

    Depositor

    Leopold Parts

    Article

    Peets et al bioRxiv 859652

    Species

    Homo sapiens

    Use

    CRISPR and Lentiviral

    Available since

    Oct. 15, 2020

    Availability

    Academic Institutions and Nonprofits only

17. Pdest-EF1α-EGFP-32bp barcode polyA library

    Pooled Library

    #211610

    Purpose

    Barcoded retrovirus plasmid library for capturing the transcriptome and viral barcode sequences of individual cells to infer their identities and lineage information.

    Depositor

    Yuejun Chen

    Article

    You et al Cell Stem Cell. 2023 Apr 6;30(4):473-487

    Species

    Synthetic

    Use

    Retroviral

    Available since

    Aug. 29, 2024

    Availability

    Academic Institutions and Nonprofits only

18. Human Paralog Knockout Library (pgPEN)

    Pooled Library

    #171172

    Purpose

    CRISPR library targets human duplicate paralog gene pairs

    Depositor

    Alice Berger

    Article

    Parrish et al Cell Rep. 2021 Aug 31;36(9):109597. doi:

    Expression

    Mammalian

    Species

    Homo sapiens and Synthetic

    Use

    CRISPR and Lentiviral

    Available since

    Sept. 28, 2021

    Availability

    Academic Institutions and Nonprofits only

19. RNA-binding protein pooled CRISPR knockout library

    Pooled Library

    #141438

    Purpose

    CRISPR knockout library targets RBPs with 10 sgRNAs/gene

    Depositor

    Eugene Yeo

    Article

    Wheeler et al Nat Methods. 2020 May 11. pii: 10.1038/s

    Expression

    Mammalian

    Use

    CRISPR and Lentiviral

    Available since

    May 28, 2020

    Availability

    Academic Institutions and Nonprofits only

20. Watermelon

    Pooled Library

    #155257

    Purpose

    Lineage tracing library

    Depositor

    Aviv Regev, Joan Brugge

    Article

    Oren et al Nature. 2021 Aug 11. pii: 10.1038/s41586

    Expression

    Mammalian

    Use

    Lentiviral

    Available since

    Oct. 15, 2021

    Availability

    Academic Institutions and Nonprofits only