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pAAV-dSa-VP64-p65(100-261)-RTA(125-190)

Plasmid

#99679

Purpose

Expresses dSa Cas9 fused to optimized combination of truncated activation domains

Depositor

George Church

Publication

Vora et al bioRxiv 2018. 298620

Insert

dCas9

Use

AAV

Tags

VP64-p65(101-261)-RTA(125-190)

Mutation

dead Cas9

Available since

Aug. 20, 2018

Availability

Academic Institutions and Nonprofits only

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pAAV-hSyn-ChRmine-eYFP-Kv2.1-WPRE

Plasmid

#130993

Purpose

AAV vector to drive the expression of soma-targeted ChRmine-eYFP under the control of human synapsin promoter

Depositor

Karl Deisseroth

Publication

Marshel et al Science. 2019 Aug 9;365(6453). pii: scie

Insert

ChRmine

Use

AAV

Tags

EYFP-Kv2.1

Promoter

hSyn

Available since

Sept. 9, 2019

Availability

Academic Institutions and Nonprofits only

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pAAV-myrSNAP-CON

Plasmid

#60099

Purpose

Expresses membrane-targeted SNAP(f)-tag and histone-GFP, conditional

Depositor

Gregory Jefferis

Publication

Kohl et al Proc Natl Acad Sci U S A. 2014 Aug 25. p

Inserts

SNAP-tag
histone-GFP

Use

AAV and Mouse Targeting

Expression

Mammalian

Available since

March 26, 2015

Availability

Academic Institutions and Nonprofits only

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pOTTC2469 - pAAV-EF1a-CreOn-MemIRFP

Plasmid

#262035

Purpose

Cre-dependent expression of a membrane bound near-infrared fluorescent protein

Depositor

Brandon Harvey, Christopher Richie

Insert

memiRFP

Use

AAV

Expression

Mammalian

Mutation

WT

Promoter

EF1a

Available since

Oct. 22, 2026

Availability

Academic Institutions and Nonprofits only

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pAAV-hSyn-anti-mCherry(LaM6) PAGER(Gi)

Plasmid

#230019

Purpose

AAV vector expressing anti-mCherry PAGER(Gi) in neurons

Depositor

Alice Ting

Publication

Kalogriopoulos et al Nature. 2024 Dec 4. doi: 10.1038/s41586-

Insert

MT1-LaM6-TEVcs-ALFA-hM1D

Use

AAV

Expression

Mammalian

Promoter

hSyn

Available since

Jan. 6, 2025

Availability

Academic Institutions and Nonprofits only

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pM124: pAAV-EFS-CasRx-VEGFA presgRNA

Plasmid

#166872

Purpose

AAV vector for expressing CasRx and human VEGFA targeting presgRNA for RNA-editing

Depositor

Guei-Sheung Liu

Publication

Chuang et al Front Cell Dev Biol. 2021 Jun 11;9:66787

Inserts

U6-VEGFA presgRNA
RfxCas13d

Use

AAV and CRISPR

Tags

HA and NLS

Expression

Mammalian

Promoter

EFS and U6

Available since

July 1, 2021

Availability

Academic Institutions and Nonprofits only

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pAAV-BD-hSynTet-TRE-DIO-mNeonGreen-MoonTag

Plasmid

#242788

Purpose

Bidirectional AAV transfer plasmid expressing hSyn-tTA and TRE-FLEX-mNeonGreen-MoonTag in the other direction.

Depositor

Andrew Payne

Inserts

mNeonGreen
tTA-Advanced

Use

AAV

Tags

MoonTag

Promoter

TRE and hSyn

Available since

Sept. 29, 2025

Availability

Academic Institutions and Nonprofits only

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pAAV-BD-hSynTet-TRE-DIO-mNeonGreen-SunTag

Plasmid

#242794

Purpose

Bidirectional AAV transfer plasmid expressing hSyn-tTA and TRE-FLEX-mNeonGreen-SunTag in the other direction.

Depositor

Andrew Payne

Inserts

mNeonGreen
tTA-Advanced

Use

AAV

Tags

SunTag

Promoter

TRE and hSyn

Available since

Sept. 29, 2025

Availability

Academic Institutions and Nonprofits only

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pAAV-K912

Plasmid

#259676

Purpose

This packaging plasmid can be used in the triple transfection method of AAV vector production.

Depositor

Leah Byrne, John Flannery

Publication

Ozturk et al Elife. 2021 Oct 19;10. pii: 64175. doi:

Insert

K912_Cap

Use

AAV

Mutation

7mer insertion in the AAV2 cap

Available since

Aug. 14, 2026

Availability

Academic Institutions and Nonprofits only

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AAV-SYN-TdTomato-RAB11

Plasmid

#203732

Purpose

AAV vector plasmid expressing human RAB11 fused to TdTomato under the human synapsin (SYN) promoter

Depositor

Richard Eva, Bart Nieuwenhuis

Insert

RAB11 (RAB11A Human)

Use

AAV

Tags

TdTomato

Expression

Mammalian

Promoter

Human synapsin promoter

Available since

July 27, 2023

Availability

Academic Institutions and Nonprofits only

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AAV-SYN-eGFP-RAB11

Plasmid

#203731

Purpose

AAV vector plasmid expressing human RAB11 fused to eGFP under the human synapsin (SYN) promoter

Depositor

Richard Eva, Bart Nieuwenhuis

Insert

RAB11 (RAB11A Human)

Use

AAV

Tags

eGFP

Expression

Mammalian

Promoter

Human synapsin promoter

Available since

July 27, 2023

Availability

Academic Institutions and Nonprofits only

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AAV-TRE-PFE3-P2A-GFP

Plasmid

#236180

Purpose

AAV version of Tet inducible PFE3 for ablating excitatory synapses.

Depositor

Don Arnold

Publication

Bareghamyan et al eLife. 2025 Apr 29;13:RP103757. doi: 10.

Insert

PFE3-P2A-GFP

Use

AAV

Available since

July 2, 2025

Availability

Academic Institutions and Nonprofits only

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AAV-CAG-PFE3-P2A-GFP

Plasmid

#236178

Purpose

AAV version of constitutive PFE3 for ablating excitatory synapses.

Depositor

Don Arnold

Publication

Bareghamyan et al eLife. 2025 Apr 29;13:RP103757. doi: 10.

Insert

PFE3-P2A-GFP

Use

AAV

Available since

July 1, 2025

Availability

Academic Institutions and Nonprofits only

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pAAV-synapsin-WHaloCaMP1a-EGFP

Plasmid

#205307

Purpose

Production of AAV particles encoding WHaloCaMP1a-EGFP from the synapsin promoter

Depositor

Eric Schreiter

Publication

Farrants et al Nat Methods. 2024 Oct;21(10):1916-1925.

Insert

WHaloCaMP1a-EGFP

Use

AAV

Available since

Aug. 18, 2023

Availability

Academic Institutions and Nonprofits only

Cited by

1 Article

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AAV-TRE-NS1-dTomato

Plasmid

#175278

Purpose

AAV vector mediating inducible bicistronic expression of NS1 gene of YFV-17D and dTomato

Depositor

Wei Xu

Publication

Li et al Nat Methods. 2021 Nov 25. pii: 10.1038/s

Insert

NS1; dTomato (POLY Yellow fever virus strain 17D)

Use

AAV

Tags

dTomato (from bidirectional promoter)

Promoter

bidirectional TRE promoter

Available since

Dec. 8, 2021

Availability

Academic Institutions and Nonprofits only

Cited by

1 Article

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pAAV-CaMKII-iGECI-NES

Plasmid

#160424

Purpose

AAV plasmid for CaMKII-driven expression of a genetically-encoded calcium indicator iGECI with a nuclear export signal sequence

Depositor

Vladislav Verkhusha

Publication

Shemetov et al Nat Biotechnol. 2021 Mar;39(3):368-377.

Insert

iGECI-NES

Use

AAV

Expression

Mammalian

Promoter

CaMKII

Available since

Jan. 7, 2021

Availability

Academic Institutions and Nonprofits only

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17_pAAV-ProB1-CatCh-GFP-WPRE

Plasmid

#125921

Purpose

Targeting expression to neuronal and glial cell types in mice, non-human primates, and human retina

Depositor

Botond Roska

Publication

Juttner et al Nat Neurosci. 2019 Jul 8. pii: 10.1038/s

Insert

CatCh-GFP

Use

AAV

Promoter

ProB1

Available since

Sept. 19, 2019

Availability

Academic Institutions and Nonprofits only

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107_pAAV-ProC17-CatCh-GFP-WPRE

Plasmid

#125952

Purpose

Targeting expression to neuronal and glial cell types in mice, non-human primates, and human retina

Depositor

Botond Roska

Publication

Juttner et al Nat Neurosci. 2019 Jul 8. pii: 10.1038/s

Insert

CatCh-GFP

Use

AAV

Promoter

ProC17

Available since

Sept. 17, 2019

Availability

Academic Institutions and Nonprofits only

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AAV-Camk2-NES-Twitch-GR

Plasmid

#173044

Purpose

TnC-based calcium sensor with green-red FRET pair ratiometric readout

Depositor

Yiyang Gong

Publication

Zhang et al Commun Biol. 2021 Jul 29;4(1):924. doi:

Has service

AAV2

Insert

NES-Twitch-GR

Use

AAV

Expression

Mammalian

Promoter

CamK2

Available since

Dec. 13, 2021

Availability

Academic Institutions and Nonprofits only

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pAAV-hSyn-ConVERGD-ArchT(eGFP)-WPRE

Plasmid

#218760

Purpose

Provides AND intersectional (Cre+Flp) expression of ArchT-eGFP

Depositor

Lindsay Schwarz

Publication

Hughes et al bioRxiv. 2023 Feb 8:2023.02.07.527312. d

Insert

ArchT

Use

AAV

Tags

eGFP

Promoter

hSyn

Available since

May 1, 2024

Availability

Academic Institutions and Nonprofits only

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