Purpose
Contains a mutant version of the WT pSynSRE-T-Luc reporter plasmid. Four point mutations in the promoter SRE elements abolish SREBP-induced luciferase expression as described by Smith et al., 1988
Insert
HMG-CoA synthase promoter (-324/-225) fused to HMG-CoA synthase TATAA (-28/+39) transcription initiator sequence
Use
Luciferase
Tags
Luciferase reporter
Expression
Mammalian
Mutation
Four point mutations (G->C or A->C) in the …
Promoter
Partial HMG-CoA synthase promoter (-324/-225) fus…
Available since
Feb. 9, 2016
Availability
Academic Institutions and Nonprofits only