We narrowed to 24,939 results for: SPR
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pUDR211
Plasmid#113870Purposeexpression of Cas9 programming sgRNA3 and sgRNA4 targetting HXT8 and HXT1 respectivelyDepositorInsertsgRNA3-HXT8 / sgRNA4-HXT14
ExpressionYeastAvailable SinceSept. 5, 2018AvailabilityAcademic Institutions and Nonprofits only -
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pLG1-puro-sgATL2-2
Plasmid#109009PurposeCRISPRi knockdown of targeted gene (to be used with Addgene #102244 or other dCas9-KRAB constructs)DepositorAvailable SinceAug. 22, 2018AvailabilityAcademic Institutions and Nonprofits only -
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pJSC236 - Bacterial expression plasmid for SpCas9 Cluster 4 + Q926A variant
Plasmid#101235PurposeBacterial expression plasmid for SpCas9 Cluster 4 + Q926A variantDepositorInsertSpCas9 variant F491A/M495A/T496A/N497A/Q926A
Tags10x His, MBP, and TEV siteExpressionBacterialMutationF491A, M495A, T496A, N497A and Q926APromoterT7Available SinceNov. 7, 2017AvailabilityAcademic Institutions and Nonprofits only -
pJSC239 - Bacterial expression plasmid for SpCas9 Cluster 3 + Q926A variant
Plasmid#101234PurposeBacterial expression plasmid for SpCas9 Cluster 3 + Q926A variantDepositorInsertSpCas9 variant T657A/G658A/W659A/R661A/Q926A
Tags10x His, MBP, and TEV siteExpressionBacterialMutationT657A, G658A, W659A, R661A and Q926APromoterT7Available SinceNov. 6, 2017AvailabilityAcademic Institutions and Nonprofits only -
pJSC269 - Bacterial expression plasmid for SpCas9 Cluster 1 + Q926A variant
Plasmid#101220PurposeBacterial expression plasmid for SpCas9 Cluster 1 + Q926A variantDepositorInsertSpCas9 variant N692A/M694A/Q695A/H698A/Q926A
Tags10x His, MBP, and TEV siteExpressionBacterialMutationN692A, M694A, Q695A, H698A and Q926APromoterT7Available SinceOct. 30, 2017AvailabilityAcademic Institutions and Nonprofits only -
pJSC197 - Bacterial expression plasmid for SpCas9 Cluster 2 + Q926A variant
Plasmid#101232PurposeBacterial expression plasmid for SpCas9 Cluster 2 + Q926A variantDepositorInsertSpCas9 variant G528A/V583A/E584A/D585A/N588A/Q926A
Tags10x His, MBP, and TEV siteExpressionBacterialMutationG528A, V583A, E584A, D585A, N588A and Q926APromoterT7Available SinceOct. 25, 2017AvailabilityAcademic Institutions and Nonprofits only -
M3-dCAS9-DNMT3A-DNMT3A (dCas9-3A-3A)
Plasmid#218776PurposeExpresses dCAS9-DNMT3A-DNMT3A fusion protein and double marker GFP-T2A-Puro under independent promotersDepositorInsertsM3-dCAS9-DNMT3A-DNMT3A (dCas9-3A-3A)
GFP-T2A-Puro
UseCRISPRExpressionMammalianAvailable SinceJan. 13, 2026AvailabilityAcademic Institutions and Nonprofits only -
M3-dCAS9-DNMT3A-DNMT3L (dCas9-3A-3L)
Plasmid#218777PurposeExpresses dCAS9-DNMT3A-DNMT3L fusion protein and double marker GFP-T2A-Puro under independent promotersDepositorInsertsM3-dCAS9-DNMT3A-DNMT3L (dCas9-3A-3L)
GFP-T2A-Puro
UseCRISPRExpressionMammalianAvailable SinceJan. 13, 2026AvailabilityAcademic Institutions and Nonprofits only -
M3-dCAS9-DNMT3A-KRAB (dCas9-3A-KRAB)
Plasmid#218781PurposeExpresses dCAS9-DNMT3A-KRAB fusion protein and double marker GFP-T2A-Puro under independent promotersDepositorInsertsM3-dCAS9-DNMT3A-DNMT3L (dCas9-3A-3L)
GFP-T2A-Puro
UseCRISPRExpressionMammalianAvailable SinceJan. 13, 2026AvailabilityAcademic Institutions and Nonprofits only -
M3-dCAS9-M.SssI (dCas9-M.SssI)
Plasmid#218782PurposeExpresses dCAS9-M.SssI fusion protein and double marker GFP-T2A-Puro under independent promotersDepositorInsertsM3-dCAS9-M.SssI (dCas9-M.SssI)
GFP-T2A-Puro
UseCRISPRExpressionMammalianAvailable SinceJan. 13, 2026AvailabilityAcademic Institutions and Nonprofits only -
M3-dCAS9-SunTag (dCas9-SunTag)
Plasmid#218783PurposeExpresses dCAS9-SunTag fusion protein and double marker GFP-T2A-Puro under independent promotersDepositorInsertsM3-dCAS9-SunTag (dCas9-SunTag)
GFP-T2A-Puro
UseCRISPRExpressionMammalianAvailable SinceJan. 13, 2026AvailabilityAcademic Institutions and Nonprofits only -
M3-dCAS9-dDNMT3A (dCas9-d3A)
Plasmid#218787PurposeExpresses dCAS9-dead DNMT3A fusion protein and double marker GFP-T2A-Puro under independent promotersDepositorInsertsM3-dCAS9-dDNMT3A (dCas9-d3A)
GFP-T2A-Puro
UseCRISPRExpressionMammalianAvailable SinceJan. 13, 2026AvailabilityAcademic Institutions and Nonprofits only -
M3-dCAS9-mutDNMT3A(R882H)(dCas9-mut3A)
Plasmid#218788PurposeExpresses dCAS9- R882H Mutated DNMT3A fusion protein and double marker GFP-T2A-Puro under independent promotersDepositorInsertsM3-dCAS9-MutDNMT3A (dCas9-Mut3A (R882H))
GFP-T2A-Puro
UseCRISPRExpressionMammalianAvailable SinceJan. 13, 2026AvailabilityAcademic Institutions and Nonprofits only -
pTCas9_scr
Plasmid#207566PurposeThermoCas9-mediated cleavage of genomic DNA in E. coliDepositorInsertPlac/tet_ThermoCas9_PlacI_lacI_PJ23119_sgRNA(scrambled non-targeting spacer)
ExpressionBacterialMutationWild-typeAvailable SinceDec. 17, 2025AvailabilityAcademic Institutions and Nonprofits only -
pGCas9_scr
Plasmid#207567PurposeGeoCas9-mediated cleavage of genomic DNA in E. coliDepositorInsertPlac/tet_GeoCas9_PlacI_lacI_PJ23119_sgRNA(scrambled non-targeting spacer)
ExpressionBacterialMutationWild-typeAvailable SinceDec. 17, 2025AvailabilityAcademic Institutions and Nonprofits only -
pdTCas9_scr
Plasmid#207568PurposedThermoCas9-mediated silencing of genomic gene in E. coliDepositorInsertPlac/tet_dThermoCas9_PlacI_lacI_PJ23119_sgRNA(scrambled non-targeting spacer)
ExpressionBacterialMutationThermoCas9(D8A,H582A)Available SinceDec. 17, 2025AvailabilityAcademic Institutions and Nonprofits only -
pdGCas9_scr
Plasmid#207569PurposedGeoCas9-mediated silencing of genomic gene in E. coliDepositorInsertPlac/tet_dGeoCas9_PlacI_lacI_PJ23119_sgRNA(scrambled non-targeting spacer)
ExpressionBacterialMutationGeoCas9(D8A,H582A)Available SinceDec. 17, 2025AvailabilityAcademic Institutions and Nonprofits only -
pHAGE-IRES-puro-NLS-HyperdLbCas12a-tagBFP-NLS-3xFlag
Plasmid#236385PurposeOverexpression of HyperdLbCas12a in human cellsDepositorInsertHyperdLbCas12a
UseCRISPR and LentiviralMutationD156R, D235R, E292R, D350RAvailable SinceDec. 1, 2025AvailabilityAcademic Institutions and Nonprofits only -
pHAGE-IRES-puro-NLS-HyperdLbCas12a-EGFP-NLS-3xFlag
Plasmid#236367PurposeOverexpression of HyperdLbCas12a in human cellsDepositorInsertHyperdLbCas12a
UseCRISPR and LentiviralMutationD156R, D235R, E292R, D350RAvailable SinceDec. 1, 2025AvailabilityAcademic Institutions and Nonprofits only -
pHAGE-IRES-puro-NLS-dLbCas12aRVRR-EGFP-NLS-3xFlag
Plasmid#236365PurposeOverexpression of dLbCas12aRVRR in human cellsDepositorInsertdLbCas12aRVRR
UseCRISPR and LentiviralMutationG532R, K538V, Y542R, K595RAvailable SinceDec. 1, 2025AvailabilityAcademic Institutions and Nonprofits only -
KLF17-CRa1-Lsg-MS2
Plasmid#247476PurposesgRNA1 for KLF17 activation cloned into LsgRNA-MS2 backboneDepositorAvailable SinceNov. 4, 2025AvailabilityAcademic Institutions and Nonprofits only -
KLF17-CRa2-Lsg-MS2
Plasmid#247477PurposegRNA2 for KLF17 activation cloned into LsgRNA-MS2 backboneDepositorAvailable SinceOct. 23, 2025AvailabilityAcademic Institutions and Nonprofits only -
pKMW493_U6-sgRNA-entry
Plasmid#244823PurposeMammalian expression of SpyCas9 single guide RNA with Golden Gate-compatible sgRNA spacerDepositorInsertSpyCas9 single guide RNA
UseCRISPRExpressionMammalianPromoterU6Available SinceSept. 17, 2025AvailabilityAcademic Institutions and Nonprofits only -
sgRNA-Dual_filler(hU6_H1)-EF1a-Thy1.1-P2A-Neo
Plasmid#239608PurposeBackbone for the cloning of a dual sgRNA expression plasmid (hU6 and H1 promoters) using BsmbI. Selectable with a G418 resistanceDepositorInsertfiller-trcr-H1-filler
UseCRISPR and LentiviralAvailable SinceSept. 16, 2025AvailabilityAcademic Institutions and Nonprofits only -
pHS72_10xHis_MBP_TEV_SpG-Cas9_2xNLS
Plasmid#244834PurposeBacterial expression of SpG Cas9 with 2xSV40 nuclear localization sequence for protein purificationDepositorInsertSpG Cas9
UseCRISPRTags10xHis-MBP and 2xSV40 NLSExpressionBacterialMutationD1135L/S1136W/G1218K/E1219Q/R1335Q/T1337RPromoterT7Available SinceSept. 16, 2025AvailabilityAcademic Institutions and Nonprofits only -
Lenti-E4-ABE-Cas9n-puro
Plasmid#226586PurposeExpress E4-ABE in mammalian cellsDepositorInsertE4-ABE
UseCRISPRExpressionMammalianAvailable SinceAug. 14, 2025AvailabilityAcademic Institutions and Nonprofits only -
Lenti-E14-ABE-Cas9n-puro
Plasmid#226588PurposeExpress E14-ABE in mammalian cellsDepositorInsertE14-ABE
UseCRISPRExpressionMammalianAvailable SinceAug. 14, 2025AvailabilityAcademic Institutions and Nonprofits only -
pCAG-48xGPBP1 array
Plasmid#236383PurposeExpression of array of 48 crRNAs targeting GPBP1DepositorInsert48xGPBP1 crRNA array (GPBP1 Human)
UseCRISPR and LentiviralAvailable SinceJuly 17, 2025AvailabilityAcademic Institutions and Nonprofits only
