59,541 results

1. Fuw-dCas9-Dnmt3a_IM

   Plasmid

   #84478

   Purpose

   Lentiviral construct to express dCas9 fused with an inactive Dnmt3a catalytic domain (E664A, E756A)

   Depositor

   Rudolf Jaenisch

   Article

   Liu et al Cell. 2016 Sep 22;167(1):233-247.e17. do

   Insert

   dCas9-Dnmt3a_IM
   

   Use

   Lentiviral

   Expression

   Mammalian

   Available Since

   Nov. 8, 2016

   Availability

   Academic Institutions and Nonprofits only

   

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2. pGFP-EB1

   Plasmid

   #17234

   Depositor

   Lynne Cassimeris

   Article

   Piehl et al Mol Biol Cell. 2003 Mar . 14(3):916-25.

   Insert

   EB1 (MAPRE1 Human)
   

   Tags

   GFP

   Expression

   Mammalian

   Available Since

   Jan. 11, 2008

   Availability

   Academic Institutions and Nonprofits only

   

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3. TFORF2158

   Plasmid

   #141949

   Purpose

   Lentiviral vector for overexpressing transcription factor ORFs with unique 24-bp barcodes. Barcodes facilitate identification of transcription factors in pooled screens.

   Depositor

   Feng Zhang

   Article

   Joung et al Cell. 2023 Jan 5;186(1):209-229.e26. doi

   Insert

   BCL11B (BCL11B Human)
   

   Use

   Lentiviral

   Expression

   Mammalian

   Promoter

   EF1a

   Available Since

   June 8, 2023

   Availability

   Academic Institutions and Nonprofits only

   

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4. pLenti6MFV SLC40A1

   Plasmid

   #194132

   Purpose

   Expresses MTP1 (SLC40A1) protein in mammalian cells

   Depositor

   Jun Liu

   Insert

   SLC40A1 (SLC40A1 Human)
   

   Use

   Lentiviral

   Expression

   Mammalian

   Available Since

   March 3, 2023

   Availability

   Academic Institutions and Nonprofits only

   

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5. pHIV-IL13-PDGFRStalk-TM

   Plasmid

   #240243

   Purpose

   Lentiviral transfer plasmid encoding IL-13 with PDGFR stalk and TM domain

   Depositor

   Michael Birnbaum

   Article

   Dobson et al Nat Methods. 2022 Apr;19(4):449-460. doi

   Insert

   IL-13 (IL13 Human)
   

   Use

   Lentiviral

   Tags

   EGFP and HA

   Expression

   Mammalian

   Promoter

   EF1a

   Available Since

   June 18, 2025

   Availability

   Academic Institutions and Nonprofits only

   

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6. pHIV-IL13-IgG4hinge-PDGFR

   Plasmid

   #240245

   Purpose

   Lentiviral transfer plasmid encoding IL13 with IgG4 hinge and PDGFR TM domain

   Depositor

   Michael Birnbaum

   Article

   Dobson et al Nat Methods. 2022 Apr;19(4):449-460. doi

   Insert

   IL-13 (IL13 Human)
   

   Use

   Lentiviral

   Tags

   EGFP and HA

   Expression

   Mammalian

   Promoter

   EF1a

   Available Since

   June 18, 2025

   Availability

   Academic Institutions and Nonprofits only

   

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7. 8061-E06

   Plasmid

   #234243

   Purpose

   Gateway ORF Entry clone of human TGFBR3 with stop codon (for native or N-terminal fusions)

   Depositor

   Dominic Esposito

   Insert

   TGFBR3 (TGFBR3 Human)
   

   Use

   Gateway entry clone

   Available Since

   May 29, 2025

   Availability

   Academic Institutions and Nonprofits only

   

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8. pAAV-hSyn-DIO-hM3D(Gq)-mCherry-shLacZ-CWB

   Plasmid

   #223660

   Purpose

   Expresses hM3D(Gq) and a control shRNA (targetting LacZ) in a Cre-dependent manner

   Depositor

   Oscar Marin

   Article

   Selten et al Nature. 2025 Apr 30. doi: 10.1038/s41586

   Insert

   hM3D(Gq)-mCherry and shLacZ
   

   Use

   AAV and RNAi

   Tags

   mCherry

   Expression

   Mammalian

   Promoter

   hSyn

   Available Since

   April 30, 2025

   Availability

   Academic Institutions and Nonprofits only

   

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9. pAAV-hSyn-DIO-hM3D(Gq)-mCherry-shVgf-CWB

   Plasmid

   #223658

   Purpose

   Expresses hM3D(Gq) and a shRNA targetting VGF in a Cre-dependent manner

   Depositor

   Oscar Marin

   Article

   Selten et al Nature. 2025 Apr 30. doi: 10.1038/s41586

   Insert

   hM3D(Gq)-mCherry and shVGF
   

   Use

   AAV and RNAi

   Tags

   mCherry

   Expression

   Mammalian

   Promoter

   hSyn

   Available Since

   April 30, 2025

   Availability

   Academic Institutions and Nonprofits only

   

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10. pAIP4_2PPN

    Plasmid

    #234190

    Purpose

    Heterologous protein expression of peptidyl-prolyl cis-trans isomerase FKBP1A (PPIase FKBP1A) in Escherichia coli

    Depositor

    Christopher Bahl

    Insert

    2PPN (FKBP1A Human)
    

    Tags

    10x HisTag-Smt3

    Expression

    Bacterial

    Promoter

    T7

    Available Since

    March 6, 2025

    Availability

    Industry, Academic Institutions, and Nonprofits

    

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11. p2T-CMV-EA-evoAPOBEC1max-32NLS_NG-BlastR

    Plasmid

    #232722

    Purpose

    C-to-T base editor

    Depositor

    David Liu

    Article

    Matuszek et al Nat Genet. 2025 May 26. doi: 10.1038/s41

    Insert

    evoAPOBEC1max H47E+S48A-32NLS linker-nCas9(NG)-UGI-UGI
    

    Expression

    Mammalian

    Mutation

    within evoAPOBEC1: H47E+S48A; within Cas9 D10A

    Available Since

    March 3, 2025

    Availability

    Academic Institutions and Nonprofits only

    

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12. p2T-U6-sgCTG

    Plasmid

    #232723

    Purpose

    SpCas9 guide RNA targeting CAG repeats for C-to-T base editing

    Depositor

    David Liu

    Article

    Matuszek et al Nat Genet. 2025 May 26. doi: 10.1038/s41

    Insert

    SpCas9 gRNA targeting CAG repeats
    

    Expression

    Mammalian

    Available Since

    March 3, 2025

    Availability

    Academic Institutions and Nonprofits only

    

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13. pLV-shFMR1-mCherry

    Plasmid

    #222963

    Purpose

    Make lentivirus to knock down human FMR1 gene

    Depositor

    Xinyu Zhao

    Article

    Guo et al Nat Commun. 2023 Jun 26;14(1):3801. doi:

    Insert

    FMR1 shRNA (FMR1 Human)
    

    Use

    Lentiviral

    Available Since

    Oct. 17, 2024

    Availability

    Academic Institutions and Nonprofits only

    

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14. pBiT3.1-N_DCAF1:1-1507

    Plasmid

    #211028

    Purpose

    Mammalian expression of full-length human DCAF1. N-terminal HiBiT tag.

    Depositor

    Cheryl Arrowsmith

    Article

    Ackloo et al J Med Chem. 2025 Jan 23;68(2):1092-1112.

    Insert

    DCAF1:M1-E1507 (DCAF1 Human)
    

    Tags

    MVSGWRLFKKISGSSGGSSG

    Expression

    Mammalian

    Mutation

    wild type

    Promoter

    CMV

    Available Since

    Feb. 21, 2024

    Availability

    Academic Institutions and Nonprofits only

    

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15. pAAV-hSyn-GFP-IRES-hSNCA (A30P)

    Plasmid

    #185720

    Purpose

    AAV expression of GFP and human α-Synuclein with A30P mutation from hSyn promoter

    Depositor

    Jun Ding

    Article

    Albarran et al Nat Neurosci. 2023 Jun;26(6):997-1007. d

    Insert

    synuclein, alpha (SNCA Human)
    

    Use

    AAV

    Mutation

    Changed Ala 30 to Pro

    Promoter

    hSyn

    Available Since

    April 21, 2023

    Availability

    Academic Institutions and Nonprofits only

    

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16. Bcr/Abl P190-pLEF

    Plasmid

    #38159

    Depositor

    Nora Heisterkamp

    Article

    Kweon et al J Biol Chem. 2008 Feb 8;283(6):3023-30.

    Insert

    BCR/ABL P190 (ABL1, BCR Human)
    

    Tags

    GST

    Expression

    Mammalian

    Mutation

    T117M in c-ABL1

    Promoter

    SV40

    Available Since

    Aug. 10, 2012

    Availability

    Academic Institutions and Nonprofits only

    

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17. pEYFP-Plk1(499)

    Plasmid

    #39843

    Depositor

    Jonathon Pines

    Article

    Lindon et al J Cell Biol. 2004 Jan 19;164(2):233-41.

    Insert

    Plk1 (PLK1 Human)
    

    Tags

    EYFP

    Expression

    Mammalian

    Available Since

    Oct. 31, 2012

    Availability

    Academic Institutions and Nonprofits only

    

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18. MADR pDonor-H3F3A-WT-EGFP pTV1 Pdgfra D842V COTv1 Trp53-V5 WPRE

    Plasmid

    #131461

    Purpose

    MADR donor plasmid for FlpO+Cre-mediated insertion of WT H3F3A and oncogenic PDGFRA D842V and TRP53

    Depositor

    Joshua Breunig

    Article

    Kim et al Cell. 2019 Sep 19;179(1):251-267.e24. do

    Insert

    H3F3A-WT-EGFP pTV1 Pdgfra D842V COTv1 Trp53-V5 WPRE
    

    Use

    Cre/Lox and Synthetic Biology; Mosaic analysis fo…

    Tags

    Trp53-V5, H3F3A-EGFP-AU1

    Expression

    Mammalian

    Mutation

    Pdgfra D842V

    Promoter

    none (4x polyA to mitigate episomal expression)

    Available Since

    July 13, 2020

    Availability

    Academic Institutions and Nonprofits only

    

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19. pDEST40-MCU-V5-HIS

    Plasmid

    #31731

    Depositor

    Vamsi Mootha

    Article

    Baughman et al Nature. 2011 Jun 19;476(7360):341-5. doi

    Insert

    MCU (MCU Human)
    

    Tags

    V5-HIS6X

    Expression

    Mammalian

    Promoter

    CMV

    Available Since

    Aug. 29, 2011

    Availability

    Academic Institutions and Nonprofits only

    

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20. p3HA-hMIB1

    Plasmid

    #33317

    Depositor

    Vanessa Redecke

    Article

    Stempin et al J Biol Chem. 2011 Oct 28;286(43):37147-5

    Insert

    MIB1 (MIB1 Human)
    

    Tags

    3xHA

    Expression

    Mammalian

    Promoter

    CMV

    Available Since

    Dec. 21, 2011

    Availability

    Academic Institutions and Nonprofits only

    

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