We narrowed to 16,047 results for: GRN

1. pX330-PCNT

   Plasmid

   #227284

   Purpose

   Expresses SpCas9 and a sgRNA targeting the N-terminus of PCNT for knock-in.

   Depositor

   Laurence Pelletier

   Article

   Philip et al EMBO J. 2024 Dec 12. doi: 10.1038/s44318

   Insert

   sgRNA Targeting N-terminus of PCNT (PCNT Human)
   

   Use

   CRISPR

   Expression

   Mammalian

   Promoter

   U6

   Available Since

   Nov. 13, 2024

   Availability

   Academic Institutions and Nonprofits only

   

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2. pX458-PLK4

   Plasmid

   #227310

   Purpose

   Expresses SpCas9 and a sgRNA targeting the C-terminus of PLK4 for knock-in.

   Depositor

   Laurence Pelletier

   Article

   Philip et al EMBO J. 2024 Dec 12. doi: 10.1038/s44318

   Insert

   sgRNA Targeting C-terminus of PLK4 (PLK4 Human)
   

   Use

   CRISPR

   Expression

   Mammalian

   Promoter

   U6

   Available Since

   Nov. 11, 2024

   Availability

   Academic Institutions and Nonprofits only

   

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3. pAAV-SCP1-dSa VPR mini.-2X snRP-1 Afp

   Plasmid

   #99696

   Purpose

   Expresses dSa Cas9 fused to optimized combination of truncated activation domains from SCP1 promoter with dual snRP1 poly adenylation signal, and Sa sgRNA for Afp, vector allows for strong activation of mouse Afp, can be packaged and delivered as AAV

   Depositor

   George Church

   Insert

   dCas9 and gRNA targeting Afp (Afp Synthetic)
   

   Use

   AAV

   Tags

   VPR mini

   Mutation

   dead Cas9

   Available Since

   Nov. 4, 2024

   Availability

   Academic Institutions and Nonprofits only

   

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4. pX330_NPM2_cterm1

   Plasmid

   #222911

   Purpose

   Cas9/sgRNA plasmid for targeting NPM2

   Depositor

   George Church

   Article

   Pierson Smela et al bioRxiv 2022.07.11.499564

   Insert

   Cas9, NPM2 sgRNA 1 (NPM2 Synthetic, Human)
   

   Use

   CRISPR

   Available Since

   July 22, 2024

   Availability

   Academic Institutions and Nonprofits only

   

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5. pX330_NPM2_cterm4

   Plasmid

   #222914

   Purpose

   Cas9/sgRNA plasmid for targeting NPM2

   Depositor

   George Church

   Article

   Pierson Smela et al bioRxiv 2022.07.11.499564

   Insert

   Cas9, NPM2 sgRNA 4 (NPM2 Synthetic, Human)
   

   Use

   CRISPR

   Available Since

   July 22, 2024

   Availability

   Academic Institutions and Nonprofits only

   

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6. pX330_NPM2_cterm3

   Plasmid

   #222913

   Purpose

   Cas9/sgRNA plasmid for targeting NPM2

   Depositor

   George Church

   Article

   Pierson Smela et al bioRxiv 2022.07.11.499564

   Insert

   Cas9, NPM2 sgRNA 3 (NPM2 Synthetic, Human)
   

   Use

   CRISPR

   Available Since

   July 22, 2024

   Availability

   Academic Institutions and Nonprofits only

   

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7. pX330_NPM2_cterm2

   Plasmid

   #222912

   Purpose

   Cas9/sgRNA plasmid for targeting NPM2

   Depositor

   George Church

   Article

   Pierson Smela et al bioRxiv 2022.07.11.499564

   Insert

   Cas9, NPM2 sgRNA 2 (NPM2 Synthetic, Human)
   

   Use

   CRISPR

   Available Since

   July 22, 2024

   Availability

   Academic Institutions and Nonprofits only

   

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8. hLig4 guide2 in pX458

   Plasmid

   #211536

   Purpose

   sgRNA-2 against Lig4

   Depositor

   Agnel Sfeir

   Article

   Brambati et al Science. 2023 Aug 11;381(6658):653-660.

   Insert

   sgRNA hLig4 (LIG4 Synthetic)
   

   Use

   CRISPR

   Expression

   Mammalian

   Promoter

   u6

   Available Since

   Jan. 22, 2024

   Availability

   Academic Institutions and Nonprofits only

   

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9. hLig4 guide1 in pX458

   Plasmid

   #211535

   Purpose

   sgRNA-1 against Lig4

   Depositor

   Agnel Sfeir

   Article

   Brambati et al Science. 2023 Aug 11;381(6658):653-660.

   Insert

   sgRNA hLig4 (LIG4 Synthetic)
   

   Use

   CRISPR

   Expression

   Mammalian

   Promoter

   u6

   Available Since

   Jan. 22, 2024

   Availability

   Academic Institutions and Nonprofits only

   

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10. 1114H

    Plasmid

    #200640

    Purpose

    An. gambiae transgenesis plasmid. Expresses gRNAs targeting B2-tubulin, ZPG, and DSXF. Crossing to Cas9 generates sterile males

    Depositor

    Omar Akbari

    Article

    Smidler et al bioRxiv [Preprint]. 2023 Jul 21:2023.07.

    Insert

    gRNA targeting DSXF, ZPG, and B2-tubulin. Actin5c-CFP and Vasa2-EYFP reporters.
    

    Use

    CRISPR

    Expression

    Insect

    Available Since

    Dec. 11, 2023

    Availability

    Academic Institutions and Nonprofits only

    

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11. pMOD_B-Pho2-1/2-2-tRNA

    Plasmid

    #161761

    Purpose

    MODULE B tRNA vector with 6x gRNAs targeting the four MsPho2-1abcd and MsPho2-2abcd genes in alfalfa (pMOD_B2303 - #91068)

    Depositor

    Shaun Curtin

    Article

    Miller et al G3 (Bethesda). 2022 May 30;12(6). pii: 6

    Insert

    gRNAs
    

    Expression

    Bacterial

    Promoter

    CmYLCV Promoter

    Available Since

    May 22, 2023

    Availability

    Academic Institutions and Nonprofits only

    

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12. GB1839

    Plasmid

    #193103

    Purpose

    GB-cassette for the expression of guide RNA targeting the DFR promoter in -376 position (gRNA2), with 2.1 Ms2 aptamer in the 3' of the scaffold.

    Depositor

    Diego Orzaez

    Article

    Moreno-Gimenez et al ACS Synth Biol. 2022 Sep 16;11(9):3037-3

    Insert

    GB_SynP gRNA2
    

    Use

    Synthetic Biology

    Available Since

    Dec. 21, 2022

    Availability

    Academic Institutions and Nonprofits only

    

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13. pSCL.108

    Plasmid

    #184977

    Purpose

    Express -Eco1 LYP1 editing ncRNA and gRNA

    Depositor

    Seth Shipman

    Article

    Lopez et al Nat Chem Biol. 2022 Feb;18(2):199-206. d

    Insert

    Eco1 editing ncRNA and gRNA, LYP1 E27X, a1/a2 length: 12
    

    Expression

    Yeast

    Mutation

    LYP1 donor E27stop

    Promoter

    Gal7

    Available Since

    Nov. 4, 2022

    Availability

    Academic Institutions and Nonprofits only

    

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14. pSCL.106

    Plasmid

    #184975

    Purpose

    Express -Eco1 CAN1 editing ncRNA and gRNA

    Depositor

    Seth Shipman

    Article

    Lopez et al Nat Chem Biol. 2022 Feb;18(2):199-206. d

    Insert

    Eco1 editing ncRNA and gRNA, CAN1 G444X, a1/a2 length: 12
    

    Expression

    Yeast

    Mutation

    CAN1 donor G444stop

    Promoter

    Gal7

    Available Since

    Nov. 4, 2022

    Availability

    Academic Institutions and Nonprofits only

    

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15. pW228-lenti-sg1-mmSerpinh1-pEF1s-NLS-mScarlet-I-P2A-BlastR

    Plasmid

    #189944

    Purpose

    Lentiviral vector to co-express a mouse Serpinh1 spsgRNA (sg1-Serpinh1) with NLS-mScarlet-I

    Depositor

    Kenneth Yamada

    Article

    Sekiguchi et al J Dent Res. 2023 Feb;102(2):197-206. doi

    Insert

    NLS-mScarlet-I-P2A-BlastR; Serpinh1 spsgRNA #1
    

    Use

    Lentiviral

    Expression

    Mammalian

    Available Since

    Nov. 3, 2022

    Availability

    Academic Institutions and Nonprofits only

    

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16. pW229-lenti-sg2-mmSerpinh1-pEF1s-NLS-mScarlet-I-P2A-BlastR

    Plasmid

    #189945

    Purpose

    Lentiviral vector to co-express a mouse Serpinh1 spsgRNA (sg2-Serpinh1) with NLS-mScarlet-I

    Depositor

    Kenneth Yamada

    Article

    Sekiguchi et al J Dent Res. 2023 Feb;102(2):197-206. doi

    Insert

    NLS-mScarlet-I-P2A-BlastR; Serpinh1 spsgRNA #2
    

    Use

    Lentiviral

    Expression

    Mammalian

    Available Since

    Nov. 3, 2022

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

17. pW230-lenti-sg3-mmSerpinh1-pEF1s-NLS-mScarlet-I-P2A-BlastR

    Plasmid

    #189946

    Purpose

    Lentiviral vector to co-express a mouse Serpinh1 spsgRNA (sg3-Serpinh1) with NLS-mScarlet-I

    Depositor

    Kenneth Yamada

    Article

    Sekiguchi et al J Dent Res. 2023 Feb;102(2):197-206. doi

    Insert

    NLS-mScarlet-I-P2A-BlastR; Serpinh1 spsgRNA #3
    

    Use

    Lentiviral

    Expression

    Mammalian

    Available Since

    Nov. 3, 2022

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

18. pW317-lenti-sg1-mmItga9-pEF1s-NLS-mScarlet-I-P2A-BlastR

    Plasmid

    #189947

    Purpose

    Lentiviral vector to co-express a mouse Itga9 spsgRNA (sg1-Itga9) with NLS-mScarlet-I

    Depositor

    Kenneth Yamada

    Article

    Sekiguchi et al J Dent Res. 2023 Feb;102(2):197-206. doi

    Insert

    NLS-mScarlet-I-P2A-BlastR; Itga9 spsgRNA #1
    

    Use

    Lentiviral

    Expression

    Mammalian

    Available Since

    Nov. 3, 2022

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

19. pW318-lenti-sg2-mmItga9-pEF1s-NLS-mScarlet-I-P2A-BlastR

    Plasmid

    #189948

    Purpose

    Lentiviral vector to co-express a mouse Itga9 spsgRNA (sg2-Itga9) with NLS-mScarlet-I

    Depositor

    Kenneth Yamada

    Article

    Sekiguchi et al J Dent Res. 2023 Feb;102(2):197-206. doi

    Insert

    NLS-mScarlet-I-P2A-BlastR; Itga9 spsgRNA #2
    

    Use

    Lentiviral

    Expression

    Mammalian

    Available Since

    Nov. 3, 2022

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

20. pW319-lenti-sg3-mmItga9-pEF1s-NLS-mScarlet-I-P2A-BlastR

    Plasmid

    #189949

    Purpose

    Lentiviral vector to co-express a mouse Itga9 spsgRNA (sg3-Itga9) with NLS-mScarlet-I

    Depositor

    Kenneth Yamada

    Article

    Sekiguchi et al J Dent Res. 2023 Feb;102(2):197-206. doi

    Insert

    NLS-mScarlet-I-P2A-BlastR; Itga9 spsgRNA #3
    

    Use

    Lentiviral

    Expression

    Mammalian

    Available Since

    Nov. 3, 2022

    Availability

    Academic Institutions and Nonprofits only

    

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