405 results

#73178

Human sgRNA library in backbone lentiGuide-Puro targeting 19,114 genes and containing 76,441 unique sgRNAs along with 1000 non-targeting controls

John Doench, David Root

Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

Feb. 9, 2016

Academic Institutions and Nonprofits only

#1000000048

CRISPR gRNA knockout pooled library for targeting the human genome

Feng Zhang

May 8, 2014

Academic Institutions and Nonprofits only

#200445

Knockout library targeting mouse cell surface genes.

Junjie Chen

Wang et al Proc Natl Acad Sci U S A. 2022 Jun 21;11

Oct. 26, 2023

Academic Institutions and Nonprofits only

#227672

RVdG genome plasmids that carry an error-correctable barcode compatible with 3’ capture single cell or single nuclei RNA sequencing readout. For the production of CVS N2c strain G-deleted rabies virus

Cathryn Cadwell, Tomasz Nowakowski

Shin et al bioRxiv [Preprint]. 2024 Dec 11:2024.10.

Feb. 12, 2025

Academic Institutions and Nonprofits only

#1000000218

Feng Zhang

March 24, 2023

Academic Institutions and Nonprofits only

#73632

Mouse sgRNA library in backbone lentiCRISPRv2 containing 78,637 unique sgRNAs targeting 19,674 genes along with 1000 non-targeting controls

John Doench, David Root

Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

Feb. 25, 2016

Academic Institutions and Nonprofits only

#247026

Human genome-wide CRISPR knockout library for the use of S. pyogenes Cas9. Each gene is targeted by 3 constructs.

John Doench, David Root

Drepanos et al bioRxiv 2025.08.26.672375; doi: https://

Oct. 2, 2025

Academic Institutions and Nonprofits only

#169942

Knockout library targeting ubiquitin ligases, deubiquitinases, and control genes.

Benjamin Ebert

Slabicki et al Nature. 2020 Sep;585(7824):293-297. doi:

Sept. 9, 2021

Academic Institutions and Nonprofits only

#73179

Human sgRNA library in backbone lentiCRISPRv2 targeting 19,114 genes and containing 76,441 unique sgRNAs along with 1000 non-targeting controls

John Doench, David Root

Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

Feb. 9, 2016

Academic Institutions and Nonprofits only

#1000000114

Genome-wide CRISPR gRNA pooled library for inhibition of human genes

John Doench, David Root

July 13, 2018

Academic Institutions and Nonprofits only

#141438

Knockout library targeting RNA-binding proteins with 10 guide RNAs per target.

Eugene Yeo

Wheeler et al Nat Methods. 2020 May 11. pii: 10.1038/s

May 28, 2020

Academic Institutions and Nonprofits only

#122131

Increases transcriptional repression of genes encoding transcription factors in combination with dCas9 repression systems, such as the dCas9-KRAB system.

Stanley Qi

Liu et al Cell Stem Cell. 2018 Sep 28. pii: S1934-

April 25, 2019

Academic Institutions and Nonprofits only

#83985

Human CRISPRa Pooled Library targeting membrane proteins

Jonathan Weissman

Horlbeck et al Elife. 2016 Sep 23;5. pii: e19760. doi:

Jan. 12, 2017

Academic Institutions and Nonprofits only

#136986

Designed for assays with limited cell numbers with 2 guides per gene. Compatible with John Doench’s Brunello human genome-wide library.

John Doench

DeWeirdt et al Nat Commun. 2020 Feb 6;11(1):752. doi: 1

Feb. 24, 2020

Academic Institutions and Nonprofits only

#171172

Induces knockouts of paralogous gene pairs. Plasmids express a pair of guide RNAs targeting either individual genes or a pair of paralogs.

Alice Berger

Parrish et al Cell Rep. 2021 Aug 31;36(9):109597. doi:

Sept. 28, 2021

Academic Institutions and Nonprofits only

#1000000049

CRISPR gRNA knockout pooled library for targeting the human genome

Feng Zhang

May 8, 2014

Academic Institutions and Nonprofits only

#83978

Version 2 of the human CRISPRa genome wide library

Jonathan Weissman

Horlbeck et al Elife. 2016 Sep 23;5. pii: e19760. doi:

Nov. 15, 2016

Academic Institutions and Nonprofits only

#233697

Barcoding pooled library

Alejo Rodriguez-Fraticelli

Singh et al Cell Stem Cell. 2025 Feb 19:S1934-5909(2

March 6, 2025

Academic Institutions and Nonprofits only

#104861

Retroviral library containing gRNAs from the Yusa lab Mouse improved genome-wide library v2.

Sarah Teichmann

Henriksson et al Cell. 2019 Jan 7. pii: S0092-8674(18)315

Sept. 9, 2019

Academic Institutions and Nonprofits only

#243681

For stable recombination of nearly all human GPCRs with unique molecular identifiers.

Jonathan Schlebach

Tedman et al bioRxiv [Preprint]. 2025 Sep 21:2025.09.

Oct. 27, 2025

Academic Institutions and Nonprofits only

#125753

Knockout library targeting a set of human interferon-stimulated genes (ISGs).

Michael Emerman, Molly OhAinle

Roesch et al Retrovirology. 2018 Mar 20;15(1):26. doi

May 7, 2020

Academic Institutions and Nonprofits only

#1000000052

CRISPR gRNA knockout pooled library for targeting the mouse genome

Feng Zhang

July 23, 2014

Academic Institutions and Nonprofits only

#248189

The CRISPRi Guest for Enrichment-based Screening of Targets Library (CRISPRi GuEST-List v1) enables genome-wide, single-cell pooled screens conducted with the Flex workflow from 10x Genomics.

Rahul Satija

Bradu et al bioRxiv 2026.02.12.705613

Feb. 17, 2026

Academic Institutions and Nonprofits only

#200013

Knockout library containing ~10,000 sgRNAs targeting 1,980 human druggable genes (5 sgRNAs per gene and 100 non-targeting control sgRNAs).

Lianxin Liu

Zheng et al Adv Sci (Weinh). 2023 Aug;10(22):e220679

May 9, 2023

Academic Institutions and Nonprofits only

#83969

Version 2 of the human CRISPRi genome wide library

Jonathan Weissman

Horlbeck et al Elife. 2016 Sep 23;5. pii: e19760. doi:

Nov. 15, 2016

Academic Institutions and Nonprofits only

#1000000264

Michael Birnbaum

Aug. 12, 2025

Academic Institutions and Nonprofits only

#207471

CRISPR-based activation library with guide RNAs targeting all cell surface proteins.

Raj Chari

Yang et al Sci Adv. 2024 Feb 16;10(7):eadj2445. doi

Jan. 24, 2024

Academic Institutions and Nonprofits only

#73633

Mouse sgRNA library in backbone lentiGuide-Puro containing 78,637 unique sgRNAs targeting 19,674 genes along with 1000 non-targeting controls

John Doench, David Root

Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

Feb. 25, 2016

Academic Institutions and Nonprofits only

#248188

The CRISPRi Guest for Enrichment-based Screening of Targets Library (CRISPRi GuEST-List v1) enables genome-wide, single-cell pooled screens conducted with the Flex workflow from 10x Genomics.

Rahul Satija

Bradu et al bioRxiv 2026.02.12.705613

Feb. 17, 2026

Academic Institutions and Nonprofits only

#75317

Mouse sgRNA library in backbone lentiCRISPRv2 targeting 713 kinase genes and containing 2,852 unique sgRNAs along with 100 non-targeting controls

John Doench, David Root

Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

June 27, 2016

Academic Institutions and Nonprofits only