390 results

#1000000082

CRISPR gRNA knockout pooled library for targeting the human kinome

John Doench, David Root

June 27, 2016

Academic Institutions and Nonprofits only

#130630

Knockout library targeting 16,977 genes. Each gene is targeted by an AsCpf1(AsCas12a)-based array containing 3-4 guides concatenated in one vector.

Giulio Draetta

Liu et al Nat Commun. 2019 Jul 17;10(1):3144. doi:

Sept. 9, 2019

Academic Institutions and Nonprofits only

#115927

~93,000 gRNAs targeting random positions along the genome of E. coli MG1655 with a NGG PAM motif. Contains ~19 targets per gene and can be used with SpdCas9 to perform pooled CRISPRi screens.

David Bikard

Cui et al Nat Commun. 2018 May 15;9(1):1912. doi:

June 6, 2019

Academic Institutions and Nonprofits only

#159392

Mouse lentiviral genome-wide CRISPR library

Jason Moffat

Lawson et al Nature. 2020 Oct;586(7827):120-126. doi:

Nov. 9, 2020

Academic Institutions and Nonprofits only

#83998

Mouse CRISPRi Pooled Library tartgeting kinsases, phosphatases and Drug Targets

Jonathan Weissman

Horlbeck et al Elife. 2016 Sep 23;5. pii: e19760. doi:

Jan. 12, 2017

Academic Institutions and Nonprofits only

#133914

CRISPR gRNA knockout pooled library for targeting the human genome - version H3

Myles Brown, Xiaole Shirley Liu

Jan. 24, 2020

Academic Institutions and Nonprofits only

#1000000124

CRISPR gRNA mouse knockout pooled library - Membrane proteins

Michael Bassik

May 23, 2018

Academic Institutions and Nonprofits only

#1000000093

Genome-wide CRISPR gRNA pooled library for activation of mouse genes

Jonathan Weissman

Nov. 15, 2016

Academic Institutions and Nonprofits only

#101927

Bassik lab Human CRISPR-Cas9 Deletion Library - Drug targets, kinases, phosphatases. Coexpresses mCherry.

Michael Bassik

Morgens et al Nat Commun. 2017 May 5;8:15178. doi: 10.

May 23, 2018

Academic Institutions and Nonprofits only

#51044

Sub-pool of Sabatini/Lander sgRNA library enriched for kinase targets.

Eric Lander, David Sabatini

Wang et al Science. 2014 Jan 3;343(6166):80-4. doi:

Feb. 7, 2014

Academic Institutions and Nonprofits only

#83994

Mouse CRISPRi Pooled Library targeting membrane proteins

Jonathan Weissman

Horlbeck et al Elife. 2016 Sep 23;5. pii: e19760. doi:

Jan. 12, 2017

Academic Institutions and Nonprofits only

#86538

Jonathan Weissman

Liu et al Science. 2017 Jan 06. Vol. 355, Issue 63

March 8, 2017

Academic Institutions and Nonprofits only

#243681

For stable recombination of nearly all human GPCRs with unique molecular identifiers.

Jonathan Schlebach

Tedman et al bioRxiv 2025.09.19.677468

Oct. 27, 2025

Academic Institutions and Nonprofits only

#234819

Unique molecular identifiers-linked sgRNA library targeting transcription factors (TFs) in mice.

Benjamin Ebert

Loke et al Blood. 2025 Jun 10:blood.2024028033. doi

June 11, 2025

Academic Institutions and Nonprofits only

#83980

Human CRISPRa Pooled Library tartgeting kinsases, phosphatases and Drug Targets

Jonathan Weissman

Horlbeck et al Elife. 2016 Sep 23;5. pii: e19760. doi:

Jan. 12, 2017

Academic Institutions and Nonprofits only

#206249

The sphingolipid metabolism library targets 82 mouse genes in the de novo ceramide and downstream sphingolipid metabolism pathways.

Kivanc Birsoy

Soula et al Nature. 2024 Aug 7. doi: 10.1038/s41586-

Aug. 29, 2024

Academic Institutions and Nonprofits only

#101928

Bassik lab Human CRISPR-Cas9 Deletion Library - Gene Expression. Coexpresses mCherry.

Michael Bassik

Morgens et al Nat Commun. 2017 May 5;8:15178. doi: 10.

May 23, 2018

Academic Institutions and Nonprofits only

#117725

Designed for genomic deletion screening of protein kinases by targeting the kinase domains.

Christopher Vakoc

Tarumoto et al Mol Cell. 2018 Feb 28. pii: S1097-2765(1

Jan. 4, 2019

Academic Institutions and Nonprofits only

#75317

Mouse sgRNA library in backbone lentiCRISPRv2 targeting 713 kinase genes and containing 2,852 unique sgRNAs along with 100 non-targeting controls

John Doench, David Root

Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

June 27, 2016

Academic Institutions and Nonprofits only

#83976

Human CRISPRi Pooled Library targeting membrane proteins

Jonathan Weissman

Horlbeck et al Elife. 2016 Sep 23;5. pii: e19760. doi:

Dec. 14, 2016

Academic Institutions and Nonprofits only

#208054

pGL0_151 [RS421] is a library of broad host range prokaryotic promoters-RBS regulatory sequences formatted as a golden gate assembly Level 0 part.

Charlie Gilbert, Nili Ostrov, Cultivarium Tools

Gilbert et al bioRxiv 2024.02.23.581749

March 21, 2024

Academic Institutions and Nonprofits only

#83999

Mouse CRISPRa Pooled Library targeting cancer and apoptosis genes

Jonathan Weissman

Horlbeck et al Elife. 2016 Sep 23;5. pii: e19760. doi:

Jan. 12, 2017

Academic Institutions and Nonprofits only

#243682

For stable recombination of nearly all human GPCRs with unique molecular identifiers.

Jonathan Schlebach

Tedman et al bioRxiv 2025.09.19.677468

Oct. 27, 2025

Academic Institutions and Nonprofits only

#1000000220

Justin English

Oct. 31, 2023

Academic Institutions and Nonprofits only

#164084

Knockout library targeting human genes required for mTORC1 activation and inhibition.

David Sabatini

Condon et al Proc Natl Acad Sci U S A. 2021 Jan 26;11

Jan. 11, 2021

Academic Institutions and Nonprofits only

#227672

RVdG genome plasmids that carry an error-correctable barcode compatible with 3’ capture single cell or single nuclei RNA sequencing readout. For the production of CVS N2c strain G-deleted rabies virus

Cathryn Cadwell, Tomasz Nowakowski

Shin et al bioRxiv [Preprint]. 2024 Dec 11:2024.10.

Feb. 12, 2025

Academic Institutions and Nonprofits only

#134583

Targets Drosophila orthologs of vertebrate genes that have undergone expansion in the vertebrate line

Norbert Perrimon

Viswanatha et al Elife. 2018 Jul 27;7. pii: 36333. doi: 1

Feb. 25, 2020

Academic Institutions and Nonprofits only

#123334

Designed for genomic deletion screening of transcription factors by targeting the DNA binding domains.

Christopher Vakoc

Huang et al Genes Dev. 2018 Jul 1;32(13-14):915-928.

May 2, 2019

Academic Institutions and Nonprofits only

#172650

Set C contains best-ranked guides 1 and 4.

John Doench, David Root

DeWeirdt et al Nat Biotechnol. 2020 Jul 13. pii: 10.103

Nov. 10, 2021

Academic Institutions and Nonprofits only

#1000000122

CRISPR gRNA mouse knockout pooled library - Drug targets, kinases, phosphatases

Michael Bassik

May 23, 2018

Academic Institutions and Nonprofits only

#160132

Plasmid library harboring a randomized 8nt PAM 3’ of target site 1. Can be used to profile CRISPR-Cas PAM requirements of enzymes that recognize 3’ PAMs (e.g. Cas9)

Keith Joung, Benjamin Kleinstiver

Walton et al Nat Protoc. 2021 Feb 5. pii: 10.1038/s41

Feb. 8, 2021

Academic Institutions and Nonprofits only

#161829

Inducible genome-wide CRISPRi library targeting S. cerevisiae genes with 6-12 guide RNAs per gene.

Saeed Tavazoie

Momen-Roknabadi et al Commun Biol. 2020 Nov 27;3(1):723. doi:

April 28, 2021

Academic Institutions and Nonprofits only

#134582

Targets kinases, phosphatases, and Drosophila orthologs of drug targets

Norbert Perrimon

Viswanatha et al Elife. 2018 Jul 27;7. pii: 36333. doi: 1

Feb. 25, 2020

Academic Institutions and Nonprofits only

#83987

Version 2 of the mouse CRISPRi genome wide library

Jonathan Weissman

Horlbeck et al Elife. 2016 Sep 23;5. pii: e19760. doi:

Nov. 15, 2016

Academic Institutions and Nonprofits only

#172109

Lentiviral peptide expression library for overexpression fitness screening

Prashant Mali

Ford et al Cell Syst. 2021 Jul 21;12(7):716-732.e7.

Oct. 21, 2021

Academic Institutions and Nonprofits only

#101930

Bassik lab Human CRISPR-Cas9 Deletion Library - Proteostasis. Coexpresses mCherry.

Michael Bassik

Morgens et al Nat Commun. 2017 May 5;8:15178. doi: 10.

May 23, 2018

Academic Institutions and Nonprofits only

#83991

Mouse CRISPRi Pooled Library targeting stress and proteostasis genes

Jonathan Weissman

Horlbeck et al Elife. 2016 Sep 23;5. pii: e19760. doi:

Jan. 12, 2017

Academic Institutions and Nonprofits only

#119977

Designed for genomic deletion screening of functional lncRNAs by targeting their splice sites.

Wensheng Wei

Liu et al Nat Biotechnol. 2018 Nov 5. pii: nbt.428

March 27, 2019

Academic Institutions and Nonprofits only

#113136

Genome-wide gRNA library for E. coli, sub3

Chong Zhang

Wang et al Nat Commun. 2018 Jun 26;9(1):2475. doi:

May 14, 2019

Academic Institutions and Nonprofits only

#113134

Genome-wide gRNA library for E. coli, sub1

Chong Zhang

Wang et al Nat Commun. 2018 Jun 26;9(1):2475. doi:

May 14, 2019

Academic Institutions and Nonprofits only