We narrowed to 270 results for: crispr

1. CRISPRi non-coding library (CRiNCL) - Common to all 7 cell lines

   Pooled Library

   #86538

   Depositor

   Jonathan Weissman

   Article

   Liu et al Science. 2017 Jan 06. Vol. 355, Issue 63

   Available since

   March 8, 2017

   Availability

   Academic Institutions and Nonprofits only

2. mU6-CR1-CRISPRiv2_hU6-CR3-NT-ctrl-guide_EF1a-PuroR-T2A-BFP

   Pooled Library

   #197348

   Purpose

   To allow for genome-wide genetic modifier screening, the library has a second fixed non-targeting control guide.

   Depositor

   Jonathan Weissman, Rebecca Voorhees

   Article

   Guna et al BMC Genomics. 2023 Oct 30;24(1):651. doi

   Species

   Homo sapiens

   Use

   Lentiviral

   Available since

   May 25, 2023

   Availability

   Academic Institutions and Nonprofits only

3. mU6-CR1-CRISPRiv2_hU6-CR3-EMC2-guide_EF1a-PuroR-T2A-BFP

   Pooled Library

   #197349

   Purpose

   To allow for genome-wide genetic modifier screening, the library has a second fixed guide targeting EMC2.

   Depositor

   Jonathan Weissman, Rebecca Voorhees

   Article

   Guna et al BMC Genomics. 2023 Oct 30;24(1):651. doi

   Species

   Homo sapiens

   Use

   Lentiviral

   Available since

   May 25, 2023

   Availability

   Academic Institutions and Nonprofits only

4. Human CRISPRa sgRNA library Calabrese in backbone XPR_502 (P65 HSF), Set A

   Pooled Library

   #92379

   Purpose

   CRISPRa

   Depositor

   John Doench, David Root

   Article

   Sanson et al Nat Commun. 2018 Dec 21;9(1):5416. doi:

   Has Service

   Lentiviral Prep

   Use

   Lentiviral

   Available since

   Aug. 3, 2017

   Availability

   Academic Institutions and Nonprofits only

5. Human CRISPRa sgRNA library Calabrese in backbone XPR_502 (P65 HSF), Set B

   Pooled Library

   #92380

   Purpose

   CRISPRa

   Depositor

   John Doench, David Root

   Article

   Sanson et al Nat Commun. 2018 Dec 21;9(1):5416. doi:

   Use

   Lentiviral

   Available since

   Aug. 3, 2017

   Availability

   Academic Institutions and Nonprofits only

6. Bassik lab Human CRISPR-Cas9 Deletion Library - Trafficking, mitochondrial, motility

   Pooled Library

   #101931

   Purpose

   Bassik lab Human CRISPR-Cas9 Deletion Library - Trafficking, mitochondrial, motility. Coexpresses mCherry.

   Depositor

   Michael Bassik

   Article

   Morgens et al Nat Commun. 2017 May 5;8:15178. doi: 10.

   Expression

   Mammalian

   Use

   CRISPR

   Available since

   May 23, 2018

   Availability

   Academic Institutions and Nonprofits only

7. Mouse CRISPRa sgRNA library Caprano in backbone XPR_502 (P65 HSF), Set A

   Pooled Library

   #92383

   Purpose

   CRISPRa

   Depositor

   John Doench, David Root

   Article

   Sanson et al Nat Commun. 2018 Dec 21;9(1):5416. doi:

   Expression

   Mammalian

   Use

   CRISPR and Lentiviral

   Available since

   July 13, 2018

   Availability

   Academic Institutions and Nonprofits only

8. Bassik lab Mouse CRISPR-Cas9 Deletion Library - Trafficking, mitochondrial, motility

   Pooled Library

   #1000000126

   Purpose

   CRISPR gRNA mouse knockout pooled library - Trafficking, mitochondrial, and motility

   Depositor

   Michael Bassik

   Available since

   May 23, 2018

   Availability

   Academic Institutions and Nonprofits only

9. CRISPRi non-coding library (CRiNCL) - Common to all 5 cancer cell lines

   Pooled Library

   #86539

   Depositor

   Jonathan Weissman

   Article

   Liu et al Science. 2017 Jan 06. Vol. 355, Issue 63

   Available since

   March 8, 2017

   Availability

   Academic Institutions and Nonprofits only

10. Mouse CRISPRa sgRNA library Caprano in backbone XPR_502 (P65 HSF), Set B

    Pooled Library

    #92384

    Purpose

    CRISPRa

    Depositor

    John Doench, David Root

    Article

    Sanson et al Nat Commun. 2018 Dec 21;9(1):5416. doi:

    Expression

    Mammalian

    Use

    CRISPR and Lentiviral

    Available since

    July 13, 2018

    Availability

    Academic Institutions and Nonprofits only

11. Compact mismatched sgRNA library for gene titration (human essential genes, CRISPRi)

    Pooled Library

    #136479

    Purpose

    Expresses gRNAs for gene titration of ~2400 human genes using CRISPRi

    Depositor

    Jonathan Weissman

    Article

    Jost et al Nat Biotechnol. 2020 Jan 13. pii: 10.103

    Expression

    Mammalian

    Species

    Homo sapiens

    Use

    CRISPR and Lentiviral

    Available since

    Feb. 25, 2020

    Availability

    Academic Institutions and Nonprofits only

12. Bassik lab Human CRISPR-Cas9 Deletion Library - Drug targets, kinases, phosphatases

    Pooled Library

    #101927

    Purpose

    Bassik lab Human CRISPR-Cas9 Deletion Library - Drug targets, kinases, phosphatases. Coexpresses mCherry.

    Depositor

    Michael Bassik

    Article

    Morgens et al Nat Commun. 2017 May 5;8:15178. doi: 10.

    Expression

    Mammalian

    Use

    CRISPR

    Available since

    May 23, 2018

    Availability

    Academic Institutions and Nonprofits only

13. Bassik lab Mouse CRISPR-Cas9 Deletion Library - Drug targets, kinases, phosphatases

    Pooled Library

    #1000000122

    Purpose

    CRISPR gRNA mouse knockout pooled library - Drug targets, kinases, phosphatases

    Depositor

    Michael Bassik

    Available since

    May 23, 2018

    Availability

    Academic Institutions and Nonprofits only

14. Human CRISPR lncRNA activation library (SAM) in lenti sgRNA(MS2)_zeo backbone

    Pooled Library

    #1000000106

    Purpose

    Human CRISPR Synergistic Activation Mediator (SAM) pooled library for the transcriptional activation of lncRNAs

    Depositor

    Feng Zhang

    Available since

    June 5, 2017

    Availability

    Academic Institutions and Nonprofits only

15. Sabatini/Lander Lab Activity-Optimized Genome-wide Human sgRNA Library in lentiCRISPR v1

    Pooled Library

    #1000000100

    Purpose

    CRISPR gRNA knockout pooled library (version 1) for targeting the human genome

    Depositor

    David Sabatini, Eric Lander

    Available since

    April 3, 2017

    Availability

    Academic Institutions and Nonprofits only

16. Large-scale mismatched sgRNA library for gene titration (human essential genes, CRISPRi)

    Pooled Library

    #136478

    Purpose

    Expresses gRNAs for gene titration of ~2400 human genes using CRISPRi

    Depositor

    Jonathan Weissman

    Article

    Jost et al Nat Biotechnol. 2020 Jan 13. pii: 10.103

    Expression

    Mammalian

    Species

    Homo sapiens

    Use

    CRISPR and Lentiviral

    Available since

    Feb. 25, 2020

    Availability

    Academic Institutions and Nonprofits only

17. Sabatini/Lander Lab Ras synthetic lethal candidate focused human sgRNA library in lentiCRISPRv1

    Pooled Library

    #92352

    Purpose

    contains 6,661 sgRNAs (comprising 499 intergenic control sgRNAs and 6,162 sgRNAs targeting 132 control and candidate Ras synthetic lethal genes at up to 50 sgRNAs per gene)

    Depositor

    David Sabatini, Eric Lander

    Article

    Wang et al Cell. 2017 Feb 1. pii: S0092-8674(17)300

    Species

    Homo sapiens

    Available since

    June 7, 2017

    Availability

    Academic Institutions and Nonprofits only

18. Wei lab paired-guide RNA (pgRNA) CRISPR–Cas9 library for human long non-coding RNAs (lncRNAs)

    Pooled Library

    #89640

    Purpose

    Paired sgRNA library containing 12,472 pgRNAs targeting 671 human long non-coding RNAs (lncRNAs)

    Depositor

    Wensheng Wei

    Article

    Zhu et al Nat Biotechnol. 2016 Dec;34(12):1279-128

    Expression

    Mammalian

    Use

    Lentiviral

    Available since

    May 17, 2017

    Availability

    Academic Institutions and Nonprofits only

19. Human messenger-RBP sgRNA library

    Pooled Library

    #168791

    Purpose

    CRISPR library targets sub-pool of human mRNA binding proteins

    Depositor

    Martin Turner

    Article

    Turner et al CRISPR J. 2021 Jun;4(3):427-437. doi: 10

    Expression

    Mammalian

    Species

    Homo sapiens

    Use

    CRISPR and Lentiviral

    Available since

    July 30, 2021

    Availability

    Academic Institutions and Nonprofits only

20. DDR_MKOv4

    Pooled Library

    #140219

    Purpose

    CRISPR DNA damage response library

    Depositor

    Junjie Chen

    Article

    Su et al DNA Repair (Amst). 2020 Jan 16;87:102803

    Expression

    Mammalian

    Species

    Homo sapiens

    Use

    CRISPR and Lentiviral

    Available since

    Aug. 20, 2021

    Availability

    Academic Institutions and Nonprofits only

21. p11-3’_8xN_PAM-site1 (RTW554)

    Pooled Library

    #160132

    Purpose

    Plasmid library harboring a randomized 8nt PAM 3’ of target site 1. Can be used to profile CRISPR-Cas PAM requirements of enzymes that recognize 3’ PAMs (e.g. Cas9)

    Depositor

    Keith Joung, Benjamin Kleinstiver

    Article

    Walton et al Nat Protoc. 2021 Feb 5. pii: 10.1038/s41

    Species

    Synthetic

    Use

    CRISPR

    Available since

    Feb. 8, 2021

    Availability

    Academic Institutions and Nonprofits only

22. p11-5’_10xN_PAM-site4 (RTW574)

    Pooled Library

    #160135

    Purpose

    Plasmid library harboring a randomized 10nt PAM 5’ of target site 4. Can be used to profile CRISPR-Cas PAM requirements of enzymes that recognize 5’ PAMs (e.g. Cas12a)

    Depositor

    Keith Joung, Benjamin Kleinstiver

    Article

    Walton et al Nat Protoc. 2021 Feb 5. pii: 10.1038/s41

    Species

    Synthetic

    Use

    CRISPR

    Available since

    Feb. 8, 2021

    Availability

    Academic Institutions and Nonprofits only

23. p11-3’_8xN_PAM-site2 (RTW555)

    Pooled Library

    #160133

    Purpose

    Plasmid library harboring a randomized 8nt PAM 3’ of target site 2. Can be used to profile CRISPR-Cas PAM requirements of enzymes that recognize 3’ PAMs (e.g. Cas9)

    Depositor

    Keith Joung, Benjamin Kleinstiver

    Article

    Walton et al Nat Protoc. 2021 Feb 5. pii: 10.1038/s41

    Species

    Synthetic

    Use

    CRISPR

    Available since

    Feb. 8, 2021

    Availability

    Academic Institutions and Nonprofits only

24. Human Whole Genome sgRNA iBAR Library

    Pooled Library

    #140633

    Purpose

    CRISPR pooled screen at high MOI by the embedded internal barcodes

    Depositor

    Wensheng Wei

    Article

    Zhu et al Genome Biol. 2019 Jan 24;20(1):20. doi:

    Use

    CRISPR and Lentiviral

    Available since

    April 21, 2020

    Availability

    Academic Institutions and Nonprofits only

25. Drosophila_sgRNA_group_2

    Pooled Library

    #134583

    Purpose

    Targets Drosophila orthologs of vertebrate genes that have undergone expansion in the vertebrate line

    Depositor

    Norbert Perrimon

    Article

    Viswanatha et al Elife. 2018 Jul 27;7. pii: 36333. doi: 1

    Expression

    Insect

    Species

    Drosophila melanogaster

    Use

    CRISPR

    Available since

    Feb. 25, 2020

    Availability

    Academic Institutions and Nonprofits only

26. Drosophila_sgRNA_group_3

    Pooled Library

    #134584

    Purpose

    Targets all other Drosophila genes not included in Groups 1 and 2

    Depositor

    Norbert Perrimon

    Article

    Viswanatha et al Elife. 2018 Jul 27;7. pii: 36333. doi: 1

    Expression

    Insect

    Species

    Drosophila melanogaster

    Use

    CRISPR

    Available since

    Feb. 25, 2020

    Availability

    Academic Institutions and Nonprofits only

27. Drosophila_sgRNA_group_1

    Pooled Library

    #134582

    Purpose

    Targets kinases, phosphatases, and Drosophila orthologs of drug targets

    Depositor

    Norbert Perrimon

    Article

    Viswanatha et al Elife. 2018 Jul 27;7. pii: 36333. doi: 1

    Expression

    Insect

    Species

    Drosophila melanogaster

    Use

    CRISPR

    Available since

    Feb. 25, 2020

    Availability

    Academic Institutions and Nonprofits only

28. Inzolia library in pRDA_550

    Pooled Library

    #209552

    Purpose

    The human, genome-wide, CRISPR knockout enAsCas12a gRNA library targets single genes and paralog pairs, triples, and quads with arrays of 4 gRNAs.

    Depositor

    John Doench

    Article

    Esmaeili Anvar et al Nat Commun. 2024 Apr 27;15(1):3577. doi:

    Use

    CRISPR and Lentiviral

    Available since

    Dec. 5, 2023

    Availability

    Academic Institutions and Nonprofits only

29. Inzolia library in pRDA_052

    Pooled Library

    #209551

    Purpose

    The human, genome-wide, CRISPR knockout enAsCas12a gRNA library targets single genes and paralog pairs, triples, and quads with arrays of 4 gRNAs.

    Depositor

    John Doench

    Article

    Esmaeili Anvar et al Nat Commun. 2024 Apr 27;15(1):3577. doi:

    Use

    CRISPR and Lentiviral

    Available since

    Dec. 5, 2023

    Availability

    Academic Institutions and Nonprofits only

30. EFS-mTSG

    Pooled Library

    #113584

    Purpose

    AAV-CRISPR library for pool mutagenesis of top tumor suppressor genes

    Depositor

    Sidi Chen

    Article

    Wang et al Sci Adv. 2018 Feb 28;4(2):eaao5508. doi:

    Expression

    Mammalian

    Use

    AAV, CRISPR, Lentiviral, and Luciferase

    Available since

    July 23, 2019

    Availability

    Academic Institutions and Nonprofits only

31. mTORC1 Focused library

    Pooled Library

    #164084

    Purpose

    Lentiviral CRISPR library targets human mTORC1 signaling pathway

    Depositor

    David Sabatini

    Article

    Condon et al Proc Natl Acad Sci U S A. 2021 Jan 26;11

    Expression

    Mammalian

    Species

    Homo sapiens

    Use

    CRISPR and Lentiviral

    Available since

    Jan. 11, 2021

    Availability

    Academic Institutions and Nonprofits only

32. Toronto KnockOut Library (TKOv1)

    Pooled Library

    #1000000069

    Purpose

    CRISPR gRNA knockout pooled library for targeting the human genome

    Depositor

    Jason Moffat, Stephane Angers

    Available since

    Jan. 28, 2016

    Availability

    Academic Institutions and Nonprofits only

33. psgRNA_EcoWG1

    Pooled Library

    #131625

    Purpose

    Improved genome-wide knockdown of E. coli genes

    Depositor

    David Bikard

    Article

    Calvo-Villamanan et al Nucleic Acids Res. 2020 Apr 30. pii: 582

    Expression

    Bacterial

    Species

    Escherichia coli

    Use

    CRISPR

    Available since

    May 12, 2020

    Availability

    Academic Institutions and Nonprofits only

34. Human SAM library in lentiSAMv2 backbone

    Pooled Library

    #1000000078

    Purpose

    Genome-wide CRISPR gRNA pooled library for activation of human genes

    Depositor

    Feng Zhang

    Available since

    June 27, 2016

    Availability

    Academic Institutions and Nonprofits only

35. TBG-mTSG

    Pooled Library

    #113585

    Purpose

    AAV-CRISPR library for pool mutagenesis of top tumor suppressor genes in mouse liver

    Depositor

    Sidi Chen

    Article

    Wang et al Sci Adv. 2018 Feb 28;4(2):eaao5508. doi:

    Expression

    Mammalian

    Use

    AAV, CRISPR, Lentiviral, and Luciferase

    Available since

    July 23, 2019

    Availability

    Academic Institutions and Nonprofits only

36. Mouse GeCKO Lentiviral sgRNA Library (LentiGuide-Puro)

    Pooled Library

    #1000000053

    Purpose

    CRISPR gRNA knockout pooled library for targeting the mouse genome

    Depositor

    Feng Zhang

    Available since

    July 23, 2014

    Availability

    Academic Institutions and Nonprofits only

37. Human Lentiviral sgRNA Library - Kinases

    Pooled Library

    #51044

    Purpose

    Sub-pool of Sabatini/Lander sgRNA library enriched for kinase targets.

    Depositor

    David Sabatini, Eric Lander

    Article

    Wang et al Science. 2014 Jan 3;343(6166):80-4. doi:

    Expression

    Mammalian

    Species

    Homo sapiens

    Use

    CRISPR and Lentiviral

    Available since

    Feb. 7, 2014

    Availability

    Academic Institutions and Nonprofits only

38. Human Lentiviral sgRNA Library - Nuclear

    Pooled Library

    #51047

    Purpose

    Sub-pool of Sabatini/Lander sgRNA library enriched for nuclear targets.

    Depositor

    David Sabatini, Eric Lander

    Article

    Wang et al Science. 2014 Jan 3;343(6166):80-4. doi:

    Expression

    Mammalian

    Species

    Homo sapiens

    Use

    CRISPR and Lentiviral

    Available since

    Feb. 7, 2014

    Availability

    Academic Institutions and Nonprofits only

39. Human Lentiviral sgRNA Library - Cell Cycle

    Pooled Library

    #51046

    Purpose

    Sub-pool of Sabatini/Lander sgRNA library enriched for cell cycle-related targets.

    Depositor

    David Sabatini, Eric Lander

    Article

    Wang et al Science. 2014 Jan 3;343(6166):80-4. doi:

    Expression

    Mammalian

    Species

    Homo sapiens

    Use

    CRISPR and Lentiviral

    Available since

    Feb. 7, 2014

    Availability

    Academic Institutions and Nonprofits only

40. Human Lentiviral sgRNA Library - Control

    Pooled Library

    #51048

    Purpose

    Sub-pool of Sabatini/Lander sgRNA library enriched for control targets.

    Depositor

    David Sabatini, Eric Lander

    Article

    Wang et al Science. 2014 Jan 3;343(6166):80-4. doi:

    Expression

    Mammalian

    Species

    Homo sapiens

    Use

    CRISPR and Lentiviral

    Available since

    Feb. 7, 2014

    Availability

    Academic Institutions and Nonprofits only