375 results

1. mCRISPRi-v2, Membrane Proteins (m6), top 5 sgRNAs/gene

   Pooled Library

   #83994

   Purpose

   Mouse CRISPRi Pooled Library targeting membrane proteins

   Depositor

   Jonathan Weissman

   Article

   Horlbeck et al Elife. 2016 Sep 23;5. pii: e19760. doi:

   Available since

   Jan. 12, 2017

   Availability

   Academic Institutions and Nonprofits only

2. RLC12

   Pooled Library

   #163954

   Purpose

   RLC12 pooled library

   Depositor

   Jeremy Rock

   Article

   Bosch et al Cell. 2021 Jul 16. pii: S0092-8674(21)00

   Expression

   Bacterial

   Use

   CRISPR

   Available since

   Oct. 1, 2021

   Availability

   Academic Institutions and Nonprofits only

3. mCRISPRi-v2, Stress and Proteostasis (m3), top 5 sgRNAs/gene

   Pooled Library

   #83991

   Purpose

   Mouse CRISPRi Pooled Library targeting stress and proteostasis genes

   Depositor

   Jonathan Weissman

   Article

   Horlbeck et al Elife. 2016 Sep 23;5. pii: e19760. doi:

   Available since

   Jan. 12, 2017

   Availability

   Academic Institutions and Nonprofits only

4. Humagne Set D

   Pooled Library

   #172651

   Purpose

   Set D contains best-ranked guides 2 and 3.

   Depositor

   David Root, John Doench

   Article

   DeWeirdt et al Nat Biotechnol. 2020 Jul 13. pii: 10.103

   Expression

   Mammalian

   Available since

   Nov. 10, 2021

   Availability

   Academic Institutions and Nonprofits only

5. hCRISPRi_dual_5_6

   Pooled Library

   #187248

   Purpose

   Ultra-compact, human genome-wide CRISPRi library targeting each gene with a single element encoding a dual sgRNA cassette.

   Depositor

   Marco Jost, Jonathan Weissman

   Article

   Replogle et al eLife. 2022 Dec 28;11:e81856. doi: 10.75

   Species

   Synthetic

   Use

   Lentiviral

   Available since

   Sept. 30, 2022

   Availability

   Academic Institutions and Nonprofits only

6. Mouse Metabolic Gene CRISPRa sgRNA library

   Pooled Library

   #187081

   Purpose

   Lentiviral CRISPRa library targeting mouse metabolic genes for activation of gene expression

   Depositor

   Kivanc Birsoy

   Article

   Unlu et al Mol Cell. 2022 Aug 4;82(15):2832-2843.e7

   Expression

   Mammalian

   Species

   Mus musculus

   Use

   Lentiviral

   Available since

   Oct. 26, 2022

   Availability

   Academic Institutions and Nonprofits only

7. Mouse CRISPRi sgRNA library Dolomiti in backbone XPR_050, Set A

   Pooled Library

   #104090

   Purpose

   Crispri

   Depositor

   David Root, John Doench

   Article

   Sanson et al Nat Commun. 2018 Dec 21;9(1):5416. doi:

   Use

   Lentiviral

   Available since

   July 13, 2018

   Availability

   Academic Institutions and Nonprofits only

8. Xiaole Shirley Liu lab Human CRISPR lentiviral library

   Pooled Library

   #1000000132

   Purpose

   CRISPR gRNA knockout pooled library for targeting the human genome

   Depositor

   Xiaole Shirley Liu

   Available since

   June 13, 2018

   Availability

   Academic Institutions and Nonprofits only

9. Bassik lab Human CRISPR-Cas9 Deletion Library - Unassigned1

   Pooled Library

   #101932

   Purpose

   Bassik lab Human CRISPR-Cas9 Deletion Library - Unassigned1. Coexpresses mCherry.

   Depositor

   Michael Bassik

   Article

   Morgens et al Nat Commun. 2017 May 5;8:15178. doi: 10.

   Expression

   Mammalian

   Use

   CRISPR

   Available since

   May 23, 2018

   Availability

   Academic Institutions and Nonprofits only

10. hCRISPRa_dual_1_2

    Pooled Library

    #187249

    Purpose

    Ultra-compact, human genome-wide CRISPRi library targeting each gene with a single element encoding a dual sgRNA cassette.

    Depositor

    Marco Jost, Jonathan Weissman

    Article

    Replogle et al eLife. 2022 Dec 28;11:e81856. doi: 10.75

    Species

    Synthetic

    Use

    Lentiviral

    Available since

    Sept. 30, 2022

    Availability

    Academic Institutions and Nonprofits only

11. PCT48

    Pooled Library

    #170392

    Purpose

    Barcoded plasmid library

    Depositor

    Jonathan Weissman

    Article

    Jones et al Genome Biol. 2020 Apr 14;21(1):92. doi:

    Expression

    Mammalian

    Species

    Synthetic

    Use

    CRISPR and Lentiviral

    Available since

    Nov. 17, 2021

    Availability

    Academic Institutions and Nonprofits only

12. TRE-MPRA_minPromega Library

    Pooled Library

    #201013

    Purpose

    Massively parallel reporter assay (MPRA) library with minPromega promoter

    Depositor

    Justin English

    Article

    Zahm et al bioRxiv. 2023 May 11:2023.05.11.539703.

    Expression

    Mammalian

    Use

    Luciferase

    Available since

    Oct. 31, 2023

    Availability

    Academic Institutions and Nonprofits only

13. LX-miR

    Pooled Library

    #112200

    Purpose

    gRNA library targets human primary miRNAs

    Depositor

    Ren-Jang Lin

    Article

    Kurata et al RNA. 2018 May 2. pii: rna.066282.118. do

    Expression

    Mammalian

    Species

    Homo sapiens

    Use

    Lentiviral

    Available since

    Sept. 20, 2018

    Availability

    Academic Institutions and Nonprofits only

14. mCRISPRi-v2, Gene Expression (m5), top 5 sgRNAs/gene

    Pooled Library

    #83993

    Purpose

    Mouse CRISPRi Pooled Library targeting gene expression

    Depositor

    Jonathan Weissman

    Article

    Horlbeck et al Elife. 2016 Sep 23;5. pii: e19760. doi:

    Available since

    Jan. 12, 2017

    Availability

    Academic Institutions and Nonprofits only

15. SPECS library

    Pooled Library

    #127842

    Purpose

    For performing high-throughput cell state-specific synthetic promoter screening

    Depositor

    Timothy Lu

    Article

    Wu et al Nat Commun. 2019 Jun 28;10(1):2880. doi:

    Species

    Synthetic

    Use

    Lentiviral

    Available since

    Aug. 22, 2020

    Availability

    Academic Institutions and Nonprofits only

16. mCRISPRi-v2, Cancer and Apoptosis (m2), top 5 sgRNAs/gene

    Pooled Library

    #83990

    Purpose

    Mouse CRISPRi Pooled Library targeting cancer and apoptosis genes

    Depositor

    Jonathan Weissman

    Article

    Horlbeck et al Elife. 2016 Sep 23;5. pii: e19760. doi:

    Available since

    Jan. 12, 2017

    Availability

    Academic Institutions and Nonprofits only

17. Barcode Library 0 (BCL0)

    Pooled Library

    #179851

    Purpose

    Lentiviral barcode library that consists of 10^6 unique barcodes. Barcodes consist of 12bp degenerate region followed by two stable bases (C or G) and 4bp unique library code ACGT.

    Depositor

    Jason Moffat

    Article

    Rehman et al Cell. 2021 Jan 7;184(1):226-242.e21. doi

    Expression

    Mammalian

    Use

    Lentiviral

    Available since

    May 12, 2022

    Availability

    Academic Institutions and Nonprofits only

18. E.coli_GW-sgRNA_Lib3

    Pooled Library

    #113136

    Purpose

    Genome-wide gRNA library for E. coli, sub3

    Depositor

    Chong Zhang

    Article

    Wang et al Nat Commun. 2018 Jun 26;9(1):2475. doi:

    Expression

    Bacterial

    Available since

    May 14, 2019

    Availability

    Academic Institutions and Nonprofits only

19. E.coli_GW-sgRNA_Lib1

    Pooled Library

    #113134

    Purpose

    Genome-wide gRNA library for E. coli, sub1

    Depositor

    Chong Zhang

    Article

    Wang et al Nat Commun. 2018 Jun 26;9(1):2475. doi:

    Expression

    Bacterial

    Available since

    May 14, 2019

    Availability

    Academic Institutions and Nonprofits only

20. mCRISPRi-v2, Mitochondria, Trafficking, and Motility (m4), top 5 sgRNAs/gene

    Pooled Library

    #83992

    Purpose

    Mouse CRISPRi Pooled Library targeting Mitochondria, Trafficking, and Motility genes

    Depositor

    Jonathan Weissman

    Article

    Horlbeck et al Elife. 2016 Sep 23;5. pii: e19760. doi:

    Available since

    Jan. 12, 2017

    Availability

    Academic Institutions and Nonprofits only

21. Mouse sgRNA library Gouda in pRDA_118 backbone

    Pooled Library

    #136987

    Purpose

    Expresses sgRNAs targeting mouse genes

    Depositor

    John Doench

    Article

    DeWeirdt et al Nat Commun. 2020 Feb 6;11(1):752. doi: 1

    Expression

    Mammalian

    Species

    Mus musculus

    Use

    CRISPR and Lentiviral

    Available since

    Feb. 24, 2020

    Availability

    Academic Institutions and Nonprofits only

22. mCRISPRi-v2, Unassigned (m7), top 5 sgRNAs/gene

    Pooled Library

    #83995

    Purpose

    Mouse CRISPRi Pooled Library targeting unassigned genes

    Depositor

    Jonathan Weissman

    Article

    Horlbeck et al Elife. 2016 Sep 23;5. pii: e19760. doi:

    Available since

    Jan. 12, 2017

    Availability

    Academic Institutions and Nonprofits only

23. E.coli_GW-sgRNA_Lib4

    Pooled Library

    #113137

    Purpose

    Genome-wide gRNA library for E. coli, sub4

    Depositor

    Chong Zhang

    Article

    Wang et al Nat Commun. 2018 Jun 26;9(1):2475. doi:

    Expression

    Bacterial

    Available since

    May 14, 2019

    Availability

    Academic Institutions and Nonprofits only

24. E.coli_GW-sgRNA_Lib2

    Pooled Library

    #113135

    Purpose

    Genome-wide gRNA library for E. coli, sub2

    Depositor

    Chong Zhang

    Article

    Wang et al Nat Commun. 2018 Jun 26;9(1):2475. doi:

    Expression

    Bacterial

    Available since

    May 14, 2019

    Availability

    Academic Institutions and Nonprofits only

25. hCRISPRi-v2, Mitochondria, Trafficking, and Motility (h4), top 5 sgRNAs/gene

    Pooled Library

    #83974

    Purpose

    Human CRISPRi Pooled Library targeting Mitochondria, Trafficking, and Motility genes

    Depositor

    Jonathan Weissman

    Article

    Horlbeck et al Elife. 2016 Sep 23;5. pii: e19760. doi:

    Available since

    Dec. 14, 2016

    Availability

    Academic Institutions and Nonprofits only

26. E.coli_NC_sgRNA_lib

    Pooled Library

    #113146

    Purpose

    Genome-wide gRNA library for E. coli, non-targeting control

    Depositor

    Chong Zhang

    Article

    Wang et al Nat Commun. 2018 Jun 26;9(1):2475. doi:

    Expression

    Bacterial

    Available since

    May 14, 2019

    Availability

    Academic Institutions and Nonprofits only

27. hCRISPRi-v2, Gene Expression (h5), top 5 sgRNAs/gene

    Pooled Library

    #83975

    Purpose

    Human CRISPRi Pooled Library targeting gene expression

    Depositor

    Jonathan Weissman

    Article

    Horlbeck et al Elife. 2016 Sep 23;5. pii: e19760. doi:

    Available since

    Dec. 14, 2016

    Availability

    Academic Institutions and Nonprofits only

28. SPLINTR BFP v1

    Pooled Library

    #179776

    Purpose

    SPLINTR (Single-cell Profiling and LINeage TRacing) is a high diversity lentiviral barcode library for tracing clonal lineages using bulk and single-cell readouts.

    Depositor

    Mark Dawson

    Article

    Fennell et al Nature. 2022 Jan;601(7891):125-131. doi:

    Expression

    Mammalian

    Use

    Lentiviral

    Available since

    May 11, 2022

    Availability

    Academic Institutions and Nonprofits only

29. pre-associated oBC-minP-GFP-mBC backbone (p043)

    Pooled Library

    #194098

    Purpose

    pre-associated oBC-minP-GFP-mBC backbone (p043), can directly be used to deposit library of regulatory elements

    Depositor

    Jay Shendure

    Article

    Lalanne et al bioRxiv 2022.12.10.519236

    Expression

    Bacterial and Mammalian

    Use

    RNAi

    Available since

    April 3, 2024

    Availability

    Academic Institutions and Nonprofits only

30. Bassik lab Human CRISPR-Cas9 Deletion Library - Unassigned3

    Pooled Library

    #101934

    Purpose

    Bassik lab Human CRISPR-Cas9 Deletion Library - Unassigned3. Coexpresses mCherry.

    Depositor

    Michael Bassik

    Article

    Morgens et al Nat Commun. 2017 May 5;8:15178. doi: 10.

    Expression

    Mammalian

    Use

    CRISPR

    Available since

    May 23, 2018

    Availability

    Academic Institutions and Nonprofits only