405 results

Showing: 241 - 270 of 405 results

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Mouse CRISPRi sgRNA library Dolomiti in backbone XPR_050, Set A

Pooled Library

#104090

Purpose

Crispri

Depositor

John Doench, David Root

Article

Sanson et al Nat Commun. 2018 Dec 21;9(1):5416. doi:

Use

Lentiviral

Available Since

July 13, 2018

Availability

Academic Institutions and Nonprofits only
Pdest-EF1α-EGFP-32bp barcode polyA library

Pooled Library

#211610

Purpose

Barcoded retrovirus plasmid library for capturing the transcriptome and viral barcode sequences of individual cells to infer their identities and lineage information.

Depositor

Yuejun Chen

Article

You et al Cell Stem Cell. 2023 Apr 6;30(4):473-487

Species

Synthetic

Use

Retroviral

Available Since

Aug. 29, 2024

Availability

Academic Institutions and Nonprofits only
Human lentiviral CRISPR library_v1

Pooled Library

#69763

Purpose

Used for genome scale lentiviral CRISPR screening. Target sites were chosen in a region close to the translation initiation site.

Depositor

Haoquan Wu

Article

Ma et al Cell Rep. 2015 Jul 28;12(4):673-83. doi:

Expression

Mammalian

Species

Homo sapiens

Use

CRISPR and Lentiviral

Available Since

Feb. 9, 2016

Availability

Academic Institutions and Nonprofits only
PBbtCRISPRko.v1

Pooled Library

#213928

Purpose

Uses the PiggyBac transposon system to deliver the library into hard to transduce cells

Depositor

Wenfang Spring Tan

Article

Tan et al PLoS Pathog. 2023 Dec 6;19(12):e1011822.

Expression

Mammalian

Use

CRISPR and Lentiviral

Available Since

April 9, 2024

Availability

Academic Institutions and Nonprofits only
scQers promoter control #5 (high: EEF1A1 promoter, p028)

Pooled Library

#217424

Purpose

scQers promoter control #5 (high: EEF1A1 promoter, p028)

Depositor

Jay Shendure

Article

Lalanne et al bioRxiv 2022.12.10.519236

Expression

Bacterial and Mammalian

Use

RNAi

Available Since

April 3, 2024

Availability

Academic Institutions and Nonprofits only
hCRISPRa-v2, Stress and Proteostasis (h3), top 5 sgRNAs/gene

Pooled Library

#83982

Purpose

Human CRISPRa Pooled Library targeting stress and proteostasis genes

Depositor

Jonathan Weissman

Article

Horlbeck et al Elife. 2016 Sep 23;5. pii: e19760. doi:

Available Since

Jan. 12, 2017

Availability

Academic Institutions and Nonprofits only
Synuclein VHH Immune Library

Pooled Library

#1000000071

Purpose

Synuclein phagemid VHH phage display library

Depositor

Anne Messer, Michael J Fox Foundation MJFF

Available Since

June 14, 2016

Availability

Industry, Academic Institutions, and Nonprofits
Liu Lab MusCK Library A

Pooled Library

#174196

Purpose

MusCK library contains 23,622 unique sgRNAs targeting 4,787 gene locations in the genome. Sub-library MusCK A contains 5 gRNAs per gene.

Depositor

Xiaole Shirley Liu

Article

Wang et al Cell. 2021 Oct 14;184(21):5357-5374.e22.

Expression

Mammalian

Species

Mus musculus

Use

CRISPR and Lentiviral

Available Since

Oct. 29, 2021

Availability

Academic Institutions and Nonprofits only
mCRISPRi-v2, Mitochondria, Trafficking, and Motility (m4), top 5 sgRNAs/gene

Pooled Library

#83992

Purpose

Mouse CRISPRi Pooled Library targeting Mitochondria, Trafficking, and Motility genes

Depositor

Jonathan Weissman

Article

Horlbeck et al Elife. 2016 Sep 23;5. pii: e19760. doi:

Available Since

Jan. 12, 2017

Availability

Academic Institutions and Nonprofits only
Mouse Liver CRISPR Knockout Library

Pooled Library

#192824

Purpose

Knockout library targeting 13,189 of the 13,266 protein-coding genes expressed in the mouse liver.

Depositor

Kristin Knouse

Article

Keys et al Cell Genom. 2022 Dec 14;2(12):100217. do

Expression

Mammalian

Species

Mus musculus

Use

CRISPR and Lentiviral

Available Since

Dec. 1, 2022

Availability

Academic Institutions and Nonprofits only
SARS-CoV-2_RBD_DMS_Library

Pooled Library

#1000000172

Depositor

Jesse Bloom

Available Since

March 29, 2021

Availability

Academic Institutions and Nonprofits only
mCRISPRi-v2, Unassigned (m7), top 5 sgRNAs/gene

Pooled Library

#83995

Purpose

Mouse CRISPRi Pooled Library targeting unassigned genes

Depositor

Jonathan Weissman

Article

Horlbeck et al Elife. 2016 Sep 23;5. pii: e19760. doi:

Available Since

Jan. 12, 2017

Availability

Academic Institutions and Nonprofits only
LibTest

Pooled Library

#113147

Purpose

Customized sgRNA library targeting 86 E. coli genes

Depositor

Chong Zhang

Article

Guo et al Nucleic Acids Res. 2018 Aug 21;46(14):70

Expression

Bacterial

Available Since

May 14, 2019

Availability

Academic Institutions and Nonprofits only
hCRISPRa-v2, Unassigned (h7), top 5 sgRNAs/gene

Pooled Library

#83986

Purpose

Human CRISPRa Pooled Library targeting unassigned genes

Depositor

Jonathan Weissman

Article

Horlbeck et al Elife. 2016 Sep 23;5. pii: e19760. doi:

Available Since

Jan. 12, 2017

Availability

Academic Institutions and Nonprofits only
pRep-Cap Scanning Saturation Mutagenesis (SSM) pooled library

Pooled Library

#199601

Purpose

pRep-Cap SSM library enables VP1, VP2, and VP3 expression under the control of the endogenous p40 promoter

Depositor

George Church

Article

Ogden et al Science. 2019 Nov 29;366(6469):1139-1143

Expression

Mammalian

Species

Aav2

Use

AAV

Available Since

June 13, 2023

Availability

Academic Institutions and Nonprofits only
Toronto KnockOut Library (TKOv1)

Pooled Library

#1000000069

Purpose

CRISPR gRNA knockout pooled library for targeting the human genome

Depositor

Stephane Angers, Jason Moffat

Available Since

Jan. 28, 2016

Availability

Academic Institutions and Nonprofits only
mCRISPRa-v2, Mitochondria, Trafficking, and Motility (m4), top 5 sgRNAs/gene

Pooled Library

#84001

Purpose

Mouse CRISPRa Pooled Library targeting Mitochondria, Trafficking, and Motility genes

Depositor

Jonathan Weissman

Article

Horlbeck et al Elife. 2016 Sep 23;5. pii: e19760. doi:

Available Since

Jan. 12, 2017

Availability

Academic Institutions and Nonprofits only
pSADB19-dTomato Barcode Library

Pooled Library

#227671

Purpose

RVdG genome plasmids that carry an error-correctable barcode compatible with 3’ capture single cell or single nuclei RNA sequencing readout. For the production of SADB19 strain G-deleted rabies virus.

Depositor

Cathryn Cadwell, Tomasz Nowakowski

Article

Shin et al bioRxiv [Preprint]. 2024 Dec 11:2024.10.

Expression

Mammalian

Species

Synthetic

Available Since

Feb. 12, 2025

Availability

Academic Institutions and Nonprofits only
scQers promoter control #2 (low: no promoter, p029)

Pooled Library

#217421

Purpose

scQers promoter control #2 (low: no promoter, p029)

Depositor

Jay Shendure

Article

Lalanne et al bioRxiv 2022.12.10.519236

Expression

Bacterial and Mammalian

Use

RNAi

Available Since

April 3, 2024

Availability

Academic Institutions and Nonprofits only
scQers promoter control #3 (intermediate: UBC promoter, p041)

Pooled Library

#217422

Purpose

scQers promoter control #3 (intermediate: UBC promoter, p041)

Depositor

Jay Shendure

Article

Lalanne et al bioRxiv 2022.12.10.519236

Expression

Bacterial and Mammalian

Use

RNAi

Available Since

April 3, 2024

Availability

Academic Institutions and Nonprofits only
scQers promoter control #4 (intermediate: Pgk1 promoter, p042)

Pooled Library

#217423

Purpose

scQers promoter control #4 (intermediate: Pgk1 promoter, p042)

Depositor

Jay Shendure

Article

Lalanne et al bioRxiv 2022.12.10.519236

Expression

Bacterial and Mammalian

Use

RNAi

Available Since

April 3, 2024

Availability

Academic Institutions and Nonprofits only
TRE-MPRA_minTK Library

Pooled Library

#201014

Purpose

Massively parallel reporter assay (MPRA) library with minTK promoter

Depositor

Justin English

Article

Zahm et al Nat Commun. 2024 Nov 28;15(1):10353. doi

Expression

Mammalian

Use

Luciferase

Available Since

Oct. 31, 2023

Availability

Academic Institutions and Nonprofits only
pUC57kan-T7-mt-gRNA library

Pooled Library

#82480

Purpose

This library is intended to be used as a technical tool for removal of mitochondrial DNA from mouse genomic DNA preparations.

Depositor

Wei Xie

Article

Wu et al Nature. 2016 Jun 30;534(7609):652-7.

Available Since

April 5, 2017

Availability

Academic Institutions and Nonprofits only
mCRISPRa-v2, Unassigned (m7), top 5 sgRNAs/gene

Pooled Library

#84004

Purpose

Mouse CRISPRa Pooled Library targeting unassigned genes

Depositor

Jonathan Weissman

Article

Horlbeck et al Elife. 2016 Sep 23;5. pii: e19760. doi:

Available Since

Jan. 12, 2017

Availability

Academic Institutions and Nonprofits only
Human Brunello kinome pooled library, guides 5-8 in lentiCRISPRv2 backbone

Pooled Library

#75315

Purpose

Human sgRNA library in backbone lentiCRISPRv2 targeting 763 kinase genes and containing 3,052 unique sgRNAs along with 100 non-targeting controls

Depositor

John Doench, David Root

Article

Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

Expression

Mammalian

Use

CRISPR and Lentiviral

Available Since

June 27, 2016

Availability

Academic Institutions and Nonprofits only
CRISPRi non-coding library (CRiNCL) - Unique to HEK293T

Pooled Library

#86543

Depositor

Jonathan Weissman

Article

Liu et al Science. 2017 Jan 06. Vol. 355, Issue 63

Available Since

March 8, 2017

Availability

Academic Institutions and Nonprofits only
CRISPRi non-coding library (CRiNCL) - Common to all 5 cancer cell lines

Pooled Library

#86539

Depositor

Jonathan Weissman

Article

Liu et al Science. 2017 Jan 06. Vol. 355, Issue 63

Available Since

March 8, 2017

Availability

Academic Institutions and Nonprofits only
CRISPRi non-coding library (CRiNCL) - Unique to K562

Pooled Library

#86544

Depositor

Jonathan Weissman

Article

Liu et al Science. 2017 Jan 06. Vol. 355, Issue 63

Available Since

March 8, 2017

Availability

Academic Institutions and Nonprofits only
p11-5’_10xN_PAM-site4 (RTW574)

Pooled Library

#160135

Purpose

Plasmid library harboring a randomized 10nt PAM 5’ of target site 4. Can be used to profile CRISPR-Cas PAM requirements of enzymes that recognize 5’ PAMs (e.g. Cas12a)

Depositor

Keith Joung, Benjamin Kleinstiver

Article

Walton et al Nat Protoc. 2021 Feb 5. pii: 10.1038/s41

Species

Synthetic

Use

CRISPR

Available Since

Feb. 8, 2021

Availability

Academic Institutions and Nonprofits only
PYR1 Double Mutant Library

Pooled Library

#1000000181

Depositor

Timothy Whitehead

Available Since

June 21, 2022

Availability

Academic Institutions and Nonprofits only

Showing: 241 - 270 of 405 results

Results per page:

Sort results by:

More Filters

405 results

Mouse CRISPRi sgRNA library Dolomiti in backbone XPR_050, Set A

Pdest-EF1α-EGFP-32bp barcode polyA library

Human lentiviral CRISPR library_v1

PBbtCRISPRko.v1

scQers promoter control #5 (high: EEF1A1 promoter, p028)

hCRISPRa-v2, Stress and Proteostasis (h3), top 5 sgRNAs/gene

Synuclein VHH Immune Library

Liu Lab MusCK Library A

mCRISPRi-v2, Mitochondria, Trafficking, and Motility (m4), top 5 sgRNAs/gene

Mouse Liver CRISPR Knockout Library

SARS-CoV-2_RBD_DMS_Library

mCRISPRi-v2, Unassigned (m7), top 5 sgRNAs/gene

LibTest

hCRISPRa-v2, Unassigned (h7), top 5 sgRNAs/gene

pRep-Cap Scanning Saturation Mutagenesis (SSM) pooled library

Toronto KnockOut Library (TKOv1)

mCRISPRa-v2, Mitochondria, Trafficking, and Motility (m4), top 5 sgRNAs/gene

pSADB19-dTomato Barcode Library

scQers promoter control #2 (low: no promoter, p029)

scQers promoter control #3 (intermediate: UBC promoter, p041)

scQers promoter control #4 (intermediate: Pgk1 promoter, p042)

TRE-MPRA_minTK Library

pUC57kan-T7-mt-gRNA library

mCRISPRa-v2, Unassigned (m7), top 5 sgRNAs/gene

Human Brunello kinome pooled library, guides 5-8 in lentiCRISPRv2 backbone

CRISPRi non-coding library (CRiNCL) - Unique to HEK293T

CRISPRi non-coding library (CRiNCL) - Common to all 5 cancer cell lines

CRISPRi non-coding library (CRiNCL) - Unique to K562

p11-5’_10xN_PAM-site4 (RTW574)

PYR1 Double Mutant Library

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