...114552 Anti-Pan-Nav1 Na+ channel [N97A/31R] Pan-Nav1 Na+ channel Human Mouse IgG2a 114553 Anti-Pan-Nav1 Na...IgG2a 211591 Anti-Pan-MAGUK [K28/86R-2b] Pan-MAGUK Human Mouse IgG2b 211592 Anti-Pan-Na+ channel [K58/...glutamate receptor Rat Mouse IgG2a 114509 Anti-Pan-FHF-A [N235/22R] Pan-FHF-A Human Mouse IgG2a 114510 Anti-REEP1... channel Mouse Mouse IgG2a 114521 Anti-Pan-QKI [N147/6.1R] Pan-QKI Human Mouse IgG2a 114525 Anti-FGF13...-2/IB-2 Mouse Mouse IgG2a 114529 Anti-Pan-SAPAP [N127/31.1R] Pan-SAPAP Rat Mouse IgG2a 114530 Anti-Neurexin...Channel Rat Mouse IgG2a 128617 Anti-Pan-Kvbeta K+ Channel [K25/73R] Pan-Kvbeta K+ Channel Mouse IgG2a 128618...External) Human Mouse IgG2a 128623 Anti-Pan-Nav Channel [K58/35R] Pan-Nav Channel Mouse IgG2a 128624 Anti-...

...Code Expansion Genetic Code Expansion You may also like... GCE4All: Making Genetic Code Expansion Accessible...Addgene's guide to plasmids and strains useful for expanding the genetic code in bacteria and mammalian cells.... Yet in the past two decades, biologists have expanded the genetic code by redirecting specific codons...amino acids beyond the 20 standard amino acids. Expanding the Genetic Code In protein translation, an aminoacyl-tRNA...incorporated into the growing peptide chain. To expand the genetic code, modified tRNAs, codons, and tRNA... the existing protein translation machinery. To expand the genetic code, 4 major changes to the standard...stimuli, such as light. On a broader scale, the expanded genetic code can help us understand and evolve...

...Browse the University of Florida serotype testing panel for the eye and brain....Service AAV University of Florida Serotype Testing Panel for the Eye and Brain Viral Vector Packaging Service...Service: University of Florida Serotype Testing Panel for the Eye and Brain You may also like: Viral Service...

...variants found across cancer types as part of a “pan-cancer” analyses. Cancer Pathways ORFs Kit : Set ...

...Knockout Library 138015 Knockout Mouse Pu N/A 6 14,671 Pan-cancer CasRx lncRNA Albarossa Library 212966 Knockout... 64750 Knockout D. melanogaster Liu N/A 3 40,279 Pan-Druggable Cancer Library 182133 Knockout Human Mali...

...DLX2.0 SYFP2 Pan GABAergic interneurons Isocortex 222939 AiP14532 AiP14532 DLX2.0 FlpO Pan GABAergic interneurons...

...cell tracing - Sean Megason Lab Zebrabow - Albert Pan and Alex Schier Labs. Multicolor fluorescent labeling...during Development and Regeneration - Periklis Pantazis Lab Multibow: digital spectral barcodes for cell...

...Villalta JE, Chen Y, Whitehead EH, Guimaraes C, Panning B, Ploegh HL, Bassik MC, Qi LS, Kampmann M, Weissman...rationally designed mutations. Researchers have expanded the CRISPR field beyond SpCas9, moving us closer...and translational technologies. Biotechnology companies are exploring therapeutic applications of CRISPR...

...E., Chen, Y., Whitehead, E. H., Guimaraes, C., Panning, B., Ploegh, H. L., Bassik, M. C., Qi, L. S., Kampmann...., Strand, C., Joung, J. K., Kleinstiver, B. P., Pan, X., Huang, A., & Doench, J. G. (2020). Optimization...effects xCas9 3.7 - mutations in multiple domains to expand PAM recognition, increase specificity, and decrease...recognizes NNTA, a PAM sequence often found in plants, expanding the targeting range for plant genome engineering...differentiation. The system is reversible, with a companion CRISPRon to undo repression using a TET1-dCas9...cleave ssDNA non-specifically. Cas12a also has an expanded targeting range to AT-rich regions, as it recognizes.... (2018). Engineered CRISPR-Cas9 nuclease with expanded targeting space. Science , 361 (6408), 1259–1262...

...you select. Suggested panels for small multiplex experiments 4-color flow panel: BV421, FITC, PE, and ...fluorophore colors in flow cytometry, but the largest panels used currently are in the mid-forties. When designing...and APC 4-color microscopy panel: DAPI for nuclei, AF488, AF555, and AF647 Antibody Selection Selecting ...again. After filtering, narrow down further by company, price, and other factors like availability and...and shipping time. Choose antibodies from companies that are known to produce reliable antibodies. Be aware...antibody can and often is licensed to multiple companies for sale. Before purchasing, directly compare ...

...reprogramming of adult pancreatic exocrine cells to beta-cells. Nature. 2008 Aug 27. Melton Pancreatic Acinar Cells.... Nature. 2011 Jun 29;475(7356):390-3. Suzuki Pancreatic Exocrine Cells Beta-cells Adenoviral Mouse In...Long-term persistence and development of induced pancreatic beta cells generated by lineage conversion of...factor-mediated reprogramming of fibroblasts to expandable, myelinogenic oligodendrocyte progenitor cells...

... 76809 PANK2 gRNA (BRDN0001149459) PANK2 hU6 Hallervorden-Spatz disease David Root 76810 PANK2 gRNA (BRDN0001162474...BRDN0001162474) PANK2 hU6 Hallervorden-Spatz disease David Root 76811 PANK2 gRNA (BRDN0001162362) PANK2 hU6 Hallervorden-Spatz...LRRK2 Parkinson's William Hahn 23583 pDONR223-PANK2 PANK2 Hallervorden-Spatz disease William Hahn 23620...Hallervorden-Spatz disease David Root 76812 PANK2 gRNA (BRDN0001144887) PANK2 hU6 Hallervorden-Spatz disease David...Ac5 Parkinson's Elisa Izaurralde 79516 5E26 (PANK2) PANK2 His, TEV polH Hallervorden-Spatz disease Cheryl...OPTN_Halo_C_allele OPTN Halo ALS Michael Ward 178145 PANK2_Halo_C_allele PANK2 Halo Hallervorden-Spatz disease Michael...

...blue, green, red, and ratiometric indicators An Expanded Palette of Genetically Encoded Ca2+ Indicators...Indicators to Image Dynamic Zn(2+) Secretion of Pancreatic Islets. Anal Chem. 2019 Oct 1;91(19):12212-12219...Genetically-encoded yellow fluorescent cAMP indicator with an expanded dynamic range for dual-color imaging. PLoS One...(cGull) Generation of a cGMP Indicator with an Expanded Dynamic Range by Optimization of Amino Acid Linkers...encoded dopamine sensor YdLight1 and RdLight1 An expanded palette of dopamine sensors for multiplex imaging...

...The list of p53 transcriptional targets is ever-expanding; the best-characterized effects of p53 are in ... have been characterized as gain-of-function, expanding the mechanisms by which mutant p53 is known to...Oct;9(10):701-13. PubMed PMID: 19693097 . The expanding universe of p53 targets. Menendez D, Inga A, Resnick...

... global research community is moving quickly to expand the knowledge and understanding of COVID-19 and...Background The Coronavirus Disease-2019 (COVID-19) pandemic is caused by a novel virus strain from the Coronaviridae...Access Collections of COVID-19 related articles spanning multiple publishers can be found here: ASM COVID...

...mouse, rat, chicken, frog, zebrafish, fly, worm, Japanese rice fish, maize, Arabidopsis, and rice. Proof-of-concept...nuclease sites, this tool from the Joung Lab has been expanded to identify potential DNA target sites for TALEs...the Database Center for Life Science (DBCLS) in Japan; Identify candidate gRNA target sequences in an ...

...great deal of interest and effort directed toward expanding this capacity. Traditionally, AAV requires the...AAV-8 cap gene in Sf9 insect cells Kotin 92307 pAnc80L65AAP Anc80L65AAP AAV packaging plasmid, expressing...Anc80L65 with endogenous AAP Vandenberghe 68837 pAnc80L65 Anc80L65 AAV packaging plasmid, expressing Rep2...

...course of an infection, adaptive immune cells will expand and give rise to memory cells that can recognize...of a high avidity BCR through repeat cycles of expansion. Chemokines Chemokines, or chemotactic cytokines...of a high avidity BCR through repeat cycles of expansion. Symbol Name Synonyms AKT1 v-akt murine thymoma... beta B29, IGB CD81 CD81 molecule S5.7, TAPA1, TSPAN28 CHP calcium binding protein P22 SLC9A1BP CHP2 calcineurin...DEF3, HNP-3, HNP3, HP-3 DEFA5 defensin, alpha 5, Paneth cell-specific DEF5, HD-5, MGC129728 DEFB1 defensin...similarity 3, member B 2-21, C21orf11, C21orf76, ORF9, PANDER, PRED44 FAM3C family with sequence similarity 3...

... and more effective treatments for carcinoid, pancreatic, and related neuroendocrine cancers. The NETRF...States and Drivers in Intestinal Carcinoid and Pancreatic Neuroendocrine Tumors...

... and Evolving Functional Proteins. METHODS: A Companion to Methods in Enzymology 8, 94–103 (1995). Carlos...Verdoes Backbones for mouse recombinant antibodies A panel of recombinant monoclonal antibodies against zebrafish...

...protein function and signaling networks continues to expand. The Rinehart and Söll labs at Yale University ...691.3 KB) Original Kit (ca. 2011) described in: Expanding the genetic code of Escherichia coli with phosphoserine...

...Flp, or Flp NOT Cre. B) This strategy has been expanded to incorporate VCre in order to enable three-feature...Deisseroth K, Zhao F, Luo MH, Gong L, He M, Zhou P, Paninski L, Li B. 2017. The central amygdala controls learning...

...Other/Trypanosoma cruzi yes, cut S. pyogenes Neo Docampo tdTomato/pTREX-b 68709 Other/Trypanosoma cruzi...

...Cre T. brucei Cross 33345 pLEW100cre-EP1 Cre Trypanosoma brucei Cross 34564 pMSCVpuro-Cre Cre 5'LTR Retroviral...MSCV-PIG-Cre Cre and GFP coexpression PGK Retroviral Pandolfi 51263 hGFAP-Roxed-Cre Dre-dependent Roxed-Cre ...

...locus function. Using CRISPR, researchers have expanded chromatin immunoprecipitation (ChIP) to allow ...

... CAP-B22 University of Florida Serotype Testing Panel for the Eye and Brain For enhanced transduction ...

...Plasmodium (malaria), Toxoplasma (toxoplasmosis), Trypanosoma (African sleeping sickness), Cryptosporidium ...

...Expression Systems Empty Backbones Genetic Code Expansion Immunology Mammalian RNAi Microbiology Plant Expression...

...CRISPR technologies are continously developing and expanding. Addgene works with leading scientists in the ...

...several modifications to the the pX458 plasmid to expand its usefulness for the lab's gene regulation and...

... research in small biotech and pharmaceutical companies. The RESOLUTE project has received funding from...

...been completed at the time of shipment. If any discrepancies are identified during this analysis, you will...

...Adenoviral Kits Plasmids containing modular inserts that span the human adenovirus serotype 5 (HAdV5) genome that...

...gets integrated into the host's genome by the accompanying integrase protein. When scientists discuss retrovirus...

...or to confirm expected labeling across a tissue panel in one of the antibody’s recommended applications...

...Transfer Agreements Most Addgene orders must be accompanied by a material transfer agreement (MTA), including...

... and OZ600 OPEN CODA aATCTTCCACAGTGATGAGGACGTGc panx2 (B1P2E8_DANRE) OZ601 and OZ602 CODA OPEN tGCCCTCTGCCGCCCTGTGGTAGCAg...

...Phosphatase and tensin homolog Rictor RPTOR independent companion of MTOR, complex 2 SGK Serum/glucocorticoid regulated...

...for this meeting's publication, we are asking participants to share practical information in the form of...

...Leishmania sp. Plasmodium sp. Toxoplasma gondii Trypanosoma sp. Plasmids for Viruses Species Dengue Hepatitis...