163,347 results

1. pcDNA3.1-CAG-NanoLuc-VChR1-EYFP

   Plasmid

   #114112

   Purpose

   fusion protein of NanoLuc, Volvox channelrhodopsin-1, and enhanced yellow fluorescent protein for bioluminescent optogenetics

   Depositor

   Ute Hochgeschwender

   Article

   Berglund et al Proc Natl Acad Sci U S A. 2016 Jan 19;11

   Insert

   NanoLuc; Volvox channelrhodopsin 1; EYFP
   

   Use

   Tags

   Expression

   Mammalian

   Mutation

   Promoter

   CAG

   Available since

   Aug. 5, 2019

   Availability

   Academic Institutions and Nonprofits only

   

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2. U6>Control(F+E)

   Plasmid

   #60006

   Purpose

   U6 promoter driving control (F+E) sgRNA

   Depositor

   Lionel Christiaen

   Article

   Stolfi et al Development. 2014 Nov;141(21):4115-20. d

   Insert

   Control (F+E) sgRNA
   

   Use

   CRISPR

   Tags

   Expression

   Mutation

   Promoter

   Ciinte.U6

   Available since

   Nov. 18, 2014

   Availability

   Academic Institutions and Nonprofits only

   

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3. pDEST15 hSlp4-a

   Plasmid

   #40046

   Depositor

   Fernando Martin-Belmonte

   Article

   Galvez-Santisteban et al Nat Cell Biol. 2012 Jul 22. doi: 10.1038

   Insert

   hSlp4-a (SYTL4 Human)
   

   Use

   Tags

   GST

   Expression

   Bacterial

   Mutation

   Promoter

   T7

   Available since

   Oct. 16, 2012

   Availability

   Academic Institutions and Nonprofits only

4. p15LZ

   Plasmid

   #169814

   Purpose

   Production of circular recombinant RNA in Escherichia coli using viroid scaffolds, tRNA ligase expression.

   Depositor

   Jose-Antonio Daros

   Article

   Daros et al Methods Mol Biol. 2021;2323:99-107. doi:

   Type

   Empty backbone

   Use

   Tags

   Expression

   Mutation

   Promoter

   Available since

   July 28, 2021

   Availability

   Academic Institutions and Nonprofits only

   

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5. pAAV-CAG-FLEX-EGFP

   Plasmid

   #59331

   Purpose

   Expresses EGFP

   Depositor

   Ian Wickersham

   Has Service

   AAV1

   Insert

   EGFP
   

   Use

   AAV and Cre/Lox

   Tags

   Expression

   Mammalian

   Mutation

   Promoter

   CAG

   Available since

   Oct. 7, 2014

   Availability

   Academic Institutions and Nonprofits only

   

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6. pC034 - LwCas13a-msfGFP-2A-Blast

   Plasmid

   #91924

   Purpose

   Expresses active LwCas13a for mammalian RNA targeting with Blasticidin selection marker

   Depositor

   Feng Zhang

   Article

   Abudayyeh et al Nature. 2017 Oct 4. doi: 10.1038/nature2

   Insert

   LwCas13a
   

   Use

   CRISPR and Lentiviral

   Tags

   NLS and msfGFP-NLS-3xHA, P2A, Blasticidin

   Expression

   Mammalian

   Mutation

   Promoter

   EFS

   Available since

   Nov. 17, 2017

   Availability

   Academic Institutions and Nonprofits only

   

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7. pCMV-GCaMP5G

   Plasmid

   #31788

   Purpose

   a single-wavelength GCaMP3-based calcium indicator with improved response. Please also see the GCaMP6s/m/f indicators.

   Depositor

   Douglas Kim, Loren Looger, GENIE Project

   Article

   Akerboom et al J Neurosci. 2012 Oct 3;32(40):13819-40.

   Insert

   GCaMP5G
   

   Use

   Tags

   6xHis, T7 epitope, and Xpress tag

   Expression

   Mammalian

   Mutation

   Promoter

   CMV

   Available since

   Aug. 22, 2011

   Availability

   Academic Institutions and Nonprofits only

   

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8. pEGFP.90 beta

   Plasmid

   #108221

   Purpose

   Mammalian expression vector for EGFP fusion to human Hsp90 beta

   Depositor

   Didier Picard

   Article

   Picard et al Exp Cell Res. 2006 Nov 15. 312(19):3949-

   Insert

   EGFP-Hsp90b (HSP90AB1 Human)
   

   Use

   Tags

   Expression

   Mammalian

   Mutation

   Promoter

   CMV

   Available since

   April 5, 2018

   Availability

   Academic Institutions and Nonprofits only

   

   Enlarge

9. pHAGE-ERBB3

   Plasmid

   #116735

   Purpose

   Lentiviral expression of ERBB3

   Depositor

   Gordon Mills, Kenneth Scott

   Article

   Ng et al Cancer Cell. 2018 Mar 12;33(3):450-462.e

   Insert

   ERBB3 (ERBB3 Human)
   

   Use

   Lentiviral

   Tags

   Expression

   Mutation

   WT

   Promoter

   Available since

   March 14, 2019

   Availability

   Academic Institutions and Nonprofits only

   

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10. Nme2Cas9_AAV

    Plasmid

    #119924

    Purpose

    All-in-one AAV plasmid expressing Nme2Cas9 with sgRNA cassette

    Depositor

    Erik Sontheimer

    Article

    Edraki et al Mol Cell. 2018 Dec 18. pii: S1097-2765(1

    Insert

    Nme2Cas9
    

    Use

    AAV

    Tags

    NLS-3xHA-NLS and NLS-NLS

    Expression

    Mammalian

    Mutation

    Promoter

    U1a

    Available since

    Jan. 18, 2019

    Availability

    Academic Institutions and Nonprofits only

    

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11. pAAV-mGFAP(ABC1D)-2pabPAC(F198Y)

    Plasmid

    #234548

    Purpose

    to express a version with reduced constitutive activity (thanks to point mutation F198Y) of the optogenetic tool 2pabPAC, which increases cAMP levels when stimulated by blue light, in astrocytes

    Depositor

    Hajime Hirase

    Article

    Vittani et al Proc Natl Acad Sci U S A. 2025 Jul 8;122

    Insert

    2pabPAC(F198Y)
    

    Use

    AAV

    Tags

    Expression

    Mutation

    F198Y

    Promoter

    mGFAP(ABC1D)

    Available since

    July 2, 2025

    Availability

    Academic Institutions and Nonprofits only

    

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12. pAAV-hSyn-GRAB-HaloDA1.0

    Plasmid

    #234408

    Purpose

    Expresses the chemigenetic dopamine (DA) sensor GRAB_HaloDA1.0 in neurons

    Depositor

    Yulong Li

    Article

    Zheng et al Science. 2025 Jun 5;388: 6751. doi: http

    Insert

    GPCR activation based chemigenetic dopamine (DA) sensor GRAB_HaloDA1.0
    

    Use

    AAV

    Tags

    Expression

    Mutation

    Promoter

    hSyn

    Available since

    June 2, 2025

    Availability

    Academic Institutions and Nonprofits only

    

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13. fabp10a:lox2272-loxp-nls-mTagBFP2-stop-lox2272-H2B-mGL-stop-loxp-mCherry-NTR2.0; cmlc2:EGFP

    Plasmid

    #230075

    Purpose

    Partial ablation using NTR2 and subsequent lineage tracing of regenerating hepatocytes in zebrafish.

    Depositor

    Sumeet Pal Singh

    Article

    Hovhannisyan et al bioRxiv 2025.05.23.655316

    Insert

    lox2272-loxp-nls-mTagBFP2-stop-lox2272-H2B-mGL-stop-loxp-mCherry-NTR2.0
    

    Use

    Cre/Lox; Zebrafish expression

    Tags

    Expression

    Mutation

    Promoter

    fabp10a

    Available since

    May 30, 2025

    Availability

    Academic Institutions and Nonprofits only

    

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14. pEGFP-TDP-43 (NLSmut)

    Plasmid

    #235489

    Purpose

    Expression of human TDP-43-EGFP with mutated nuclear localization sequence

    Depositor

    Maxime Rousseaux

    Article

    Suk et al Mol Neurodegener. 2025 Mar 28;20(1):38.

    Insert

    TARDBP (TARDBP Human)
    

    Use

    Tags

    EGFP

    Expression

    Mammalian

    Mutation

    K82A, R83A, K84A, K95A, K97A, R98A

    Promoter

    Available since

    May 19, 2025

    Availability

    Industry, Academic Institutions, and Nonprofits

    

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15. pAG Lenti CMV EGFP Puro

    Plasmid

    #236084

    Purpose

    Lentiviral backbone expressing EGFP, control for empty backbone 236083

    Depositor

    Melina Fan

    Insert

    EGFP
    

    Use

    Lentiviral

    Tags

    Expression

    Mutation

    Promoter

    CMV

    Available since

    April 25, 2025

    Availability

    Industry, Academic Institutions, and Nonprofits

    

    Enlarge

16. AAV r3.45

    Plasmid

    #233684

    Purpose

    An evolved Adeno-associated viral variant, enhances gene delivery and gene targeting in neural stem cells

    Depositor

    David Schaffer

    Article

    Jang et al Mol Ther. 2011 Apr;19(4):667-75. doi: 10

    Insert

    Modified AAV2 Rep, Cap
    

    Use

    AAV

    Tags

    Expression

    Mutation

    insertion of LATQVGQKTA (where LA and A are linke…

    Promoter

    Available since

    April 24, 2025

    Availability

    Academic Institutions and Nonprofits only

    

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17. TFORF2874

    Plasmid

    #143649

    Purpose

    Lentiviral vector for overexpressing transcription factor ORFs with unique 24-bp barcodes. Barcodes facilitate identification of transcription factors in pooled screens.

    Depositor

    Feng Zhang

    Article

    Joung et al Cell. 2023 Jan 5;186(1):209-229.e26. doi

    Insert

    ELF1 (ELF1 Human)
    

    Use

    Lentiviral

    Tags

    Expression

    Mammalian

    Mutation

    Promoter

    EF1a

    Available since

    Feb. 27, 2025

    Availability

    Academic Institutions and Nonprofits only

    

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18. Coxsackievirus B3 (CVB3) 3C protease isolate KR-2002

    Plasmid

    #228639

    Purpose

    Bacterial expression of the Coxsackievirus 33 isoform B 3C protease

    Depositor

    ASAP Discovery, Frank von Delft

    Insert

    Coxsackievirus 33 isoform B 3C protease
    

    Use

    Tags

    His-SUMO

    Expression

    Bacterial

    Mutation

    Promoter

    Available since

    Feb. 14, 2025

    Availability

    Industry, Academic Institutions, and Nonprofits

    

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19. AiP14187 - pAAV-AiE0459m_3xC2-minBG-iCre(R297T)-BGHpA (Alias: CN4187)

    Plasmid

    #229920

    Purpose

    AiE0459m_3xC2 is an enhancer sequence, designed to drive AAV-mediated transgene expression in specific brain cell types

    Depositor

    Jonathan Ting, The Allen Institute for Brain Science

    Article

    Ben-Simon et al Cell. 2025 May 16:S0092-8674(25)00513-6.

    Insert

    iCre(R297T)
    

    Use

    AAV

    Tags

    Expression

    Mutation

    Promoter

    Available since

    Feb. 6, 2025

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

20. pJet-CMV-IARS1[W435C]-GFP

    Plasmid

    #212323

    Purpose

    EGFP-tagged IARS1 Trp435Cys

    Depositor

    Sabine Fuchs

    Article

    Kok et al Nucleic Acids Res. 2025 Jan 7;53(1):gkae

    Insert

    IARS (IARS1 Human)
    

    Use

    Tags

    EGFP

    Expression

    Mammalian

    Mutation

    Trp435cys

    Promoter

    CMV

    Available since

    Nov. 27, 2024

    Availability

    Academic Institutions and Nonprofits only

    

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