Addgene

We narrowed to 1,461 results for: p53

Showing: 451 - 500 of 1461 results

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pCRII Pig9

Plasmid

#16503

Depositor

Bert Vogelstein

Article

Polyak et al Nature. 1997 Sep 18. 389(6648):300-5.

Insert

Pig9 (MAD1L1 Human)

Use

Tags

Expression

Bacterial

Mutation

Partial cDNA clone

Promoter

Available since

April 24, 2008

Availability

Academic Institutions and Nonprofits only
p3039 pVL E6-AP

Plasmid

#8646

Depositor

Peter Howley

Article

Huibregtse et al Mol Cell Biol 1993 Aug;13(8):4918-27.

Insert

E6-AP (UBE3A Human)

Use

Tags

Expression

Insect

Mutation

Promoter

Available since

June 16, 2005

Availability

Academic Institutions and Nonprofits only
MSCV-PM-BAF180-SH2

Plasmid

#41932

Depositor

Stephen Elledge

Article

Burrows et al Proc Natl Acad Sci U S A. 2010 Aug 10;10

Insert

BAF180

Use

Retroviral

Tags

Expression

Mammalian

Mutation

Promoter

Available since

May 10, 2013

Availability

Academic Institutions and Nonprofits only
MSCV-PM-BAF180-SH3

Plasmid

#41933

Depositor

Stephen Elledge

Article

Burrows et al Proc Natl Acad Sci U S A. 2010 Aug 10;10

Insert

BAF180

Use

Retroviral

Tags

Expression

Mammalian

Mutation

Promoter

Available since

May 10, 2013

Availability

Academic Institutions and Nonprofits only
MSCV-PM-BAF180-SH1

Plasmid

#41931

Depositor

Stephen Elledge

Article

Burrows et al Proc Natl Acad Sci U S A. 2010 Aug 10;10

Insert

BAF180

Use

Retroviral

Tags

Expression

Mammalian

Mutation

Promoter

Available since

May 10, 2013

Availability

Academic Institutions and Nonprofits only
pcDNA3-6XHis-human SUMO 2

Plasmid

#133771

Purpose

express 6Xhis- SUMO 2 protein

Depositor

Martine Roussel

Article

Tago et al Proc Natl Acad Sci U S A. 2005 May 24. 1

Insert

SUMO 2 (SUMO2 Human)

Use

Tags

6XHis

Expression

Mammalian

Mutation

Promoter

CMV

Available since

Dec. 6, 2019

Availability

Academic Institutions and Nonprofits only

Enlarge
pcDNA3-6Xhis-human SUMO 3

Plasmid

#133772

Purpose

express 6Xhis- SUMO 3 protein

Depositor

Martine Roussel

Article

Tago et al Proc Natl Acad Sci U S A. 2005 May 24. 1

Insert

SUMO 3 (SUMO3 Human)

Use

Tags

6XHis

Expression

Mammalian

Mutation

Promoter

CMV

Available since

Dec. 6, 2019

Availability

Academic Institutions and Nonprofits only

Enlarge
Flag-TRIM24

Plasmid

#28138

Depositor

Michelle Barton

Article

Allton et al Proc Natl Acad Sci U S A. 2009 Jul 14. 1

Insert

TRIM24 (TRIM24 Human)

Use

Tags

FLAGX2

Expression

Mammalian

Mutation

Promoter

Available since

June 6, 2011

Availability

Academic Institutions and Nonprofits only

Enlarge
p3869 HA-E6-AP C833A

Plasmid

#8649

Depositor

Peter Howley

Article

Talis et al J Biol Chem 1998 Mar 13;273(11):6439-45.

Insert

E6-AP (UBE3A Human)

Use

Tags

HA

Expression

Mammalian

Mutation

C833A; active site Cys mutated to encode Ala

Promoter

Available since

Oct. 11, 2005

Availability

Academic Institutions and Nonprofits only
pLminP_Luc2P_RE21

Plasmid

#90363

Purpose

p53 - Apoptosis gene reporter

Depositor

Ramnik Xavier

Article

O'Connell et al Cell Syst. 2016 May 25;2(5):323-34. doi:

Insert

Firefly luciferase

Use

Lentiviral

Tags

Expression

Mutation

Promoter

p53

Available since

May 23, 2022

Availability

Academic Institutions and Nonprofits only

Enlarge
pMXs-DsRed Express

Plasmid

#22724

Depositor

Shinya Yamanaka

Article

Hong et al Nature. 2009 Aug 27. 460(7259):1132-5.

Insert

a variant of Discosoma sp. red fluorescent protein

Use

Retroviral

Tags

Expression

Mammalian

Mutation

N/A

Promoter

Available since

Dec. 10, 2009

Availability

Academic Institutions and Nonprofits only

Enlarge
pLKO-PTEN-shRNA-3001

Plasmid

#25639

Depositor

Todd Waldman

Article

Kim et al Mol Cell Biol. 2007 Jan . 27(2):662-77.

Insert

PTEN-shRNA-3001 (PTEN Human)

Use

Lentiviral and RNAi

Tags

Expression

Mammalian

Mutation

Promoter

Available since

June 21, 2010

Availability

Academic Institutions and Nonprofits only

Enlarge
pLKO-PTEN-shRNA-1320

Plasmid

#25638

Depositor

Todd Waldman

Article

Kim et al Mol Cell Biol. 2007 Jan . 27(2):662-77.

Insert

PTEN-shRNA-1320 (PTEN Human)

Use

Lentiviral and RNAi

Tags

Expression

Mammalian

Mutation

Promoter

Available since

June 21, 2010

Availability

Academic Institutions and Nonprofits only

Enlarge
HP138-puro

Plasmid

#134246

Purpose

Cas9 in a transposon array under a Tet inducible promoter. For making inducible Cas9 cell lines. Puro selection.

Depositor

Iain Cheeseman

Article

McKinley et al Dev Cell. 2017 Feb 27;40(4):405-420.e2.

Insert

Contains Cas9

Use

CRISPR

Tags

Expression

Mutation

Promoter

Available since

Feb. 6, 2020

Availability

Academic Institutions and Nonprofits only

Enlarge
NdeI – SacII – SpeI(NheI) - ANXA2 (23-339)

Plasmid

#136543

Purpose

Expresses ANXA2 chimeras in bacterial cells

Depositor

Laszlo Nyitray

Article

Ecsedi et al Structure. 2020 Aug 4;28(8):943-953.e4.

Type

Empty backbone

Use

Tags

ANXA2 (23-339) and His-tag

Expression

Bacterial

Mutation

Promoter

Available since

May 15, 2020

Availability

Academic Institutions and Nonprofits only

Enlarge
pCMV MDM-2

Plasmid

#16441

Depositor

Bert Vogelstein

Article

Oliner et al Nature. 1992 Jul 2. 358(6381):80-3.

Insert

MDM2 (MDM2 Human)

Use

Tags

Expression

Mammalian

Mutation

Promoter

Available since

June 11, 2008

Availability

Academic Institutions and Nonprofits only

Enlarge
pKM808

Plasmid

#134181

Purpose

Lentiviral sgRNA plasmid with blasticidin resistance

Depositor

Iain Cheeseman

Article

McKinley et al Dev Cell. 2017 Feb 27;40(4):405-420.e2.

Type

Empty backbone

Use

Lentiviral

Tags

Expression

Mammalian

Mutation

Promoter

Available since

Feb. 21, 2020

Availability

Academic Institutions and Nonprofits only

Enlarge
pFlag-CMV2-Smyd2

Plasmid

#13521

Depositor

Shelley Berger

Article

Huang et al Nature. 2006 Nov 30. 444(7119):629-32.

Insert

Smyd2 (Smyd2 Mouse)

Use

Tags

Flag

Expression

Mammalian

Mutation

Promoter

Available since

Feb. 1, 2007

Availability

Academic Institutions and Nonprofits only
pLL3.7_hsa-miR-150

Plasmid

#25792

Depositor

Judy Lieberman

Article

Navarro et al Blood. 2009 Sep 3. 114(10):2181-92.

Insert

hsa-miR-150 (MIR150, MYB Human)

Use

Lentiviral and RNAi

Tags

Expression

Mutation

Promoter

Available since

July 13, 2010

Availability

Academic Institutions and Nonprofits only
pSIREN-RetroQ-MYB-shRNA

Plasmid

#25790

Depositor

Judy Lieberman

Article

Navarro et al Blood. 2009 Sep 3. 114(10):2181-92.

Insert

shRNA against human MYB (MYB Human)

Use

RNAi and Retroviral

Tags

Expression

Mammalian

Mutation

Promoter

Available since

July 13, 2010

Availability

Academic Institutions and Nonprofits only
pLP-LNCX-PIK3CA-H1047R

Plasmid

#25635

Depositor

Todd Waldman

Article

Kim et al Mol Cell Biol. 2007 Jan . 27(2):662-77.

Insert

PIK3CA (PIK3CA Human)

Use

Retroviral

Tags

Expression

Mammalian

Mutation

Promoter

Available since

Oct. 20, 2010

Availability

Academic Institutions and Nonprofits only
pLP-LNCX-PIK3CA-WT

Plasmid

#25633

Depositor

Todd Waldman

Article

Kim et al Mol Cell Biol. 2007 Jan . 27(2):662-77.

Insert

PIK3CA (PIK3CA Human)

Use

Retroviral

Tags

FLAG

Expression

Mammalian

Mutation

Promoter

Available since

June 21, 2010

Availability

Academic Institutions and Nonprofits only
4XBS2WT-Luc

Plasmid

#16593

Depositor

Bert Vogelstein

Article

Yu et al Mol Cell. 2001 Mar . 7(3):673-82.

Insert

p53 binding sites (TP53 Human)

Use

Luciferase

Tags

Luciferase

Expression

Mammalian

Mutation

Promoter

Available since

March 28, 2008

Availability

Academic Institutions and Nonprofits only
pCMV HDM2(NES-)

Plasmid

#12087

Depositor

Tyler Jacks

Article

Boyd et al Nat Cell Biol. 2000 Sep . 2(9):563-8.

Insert

HDM2 (MDM2 Human)

Use

Tags

Expression

Mammalian

Mutation

Nuclear-export sequence mutant (NES-): L205A, I20…

Promoter

Available since

June 8, 2006

Availability

Academic Institutions and Nonprofits only
pBR322 14-3-3 Promoter

Plasmid

#16517

Depositor

Bert Vogelstein

Article

Hermeking et al Mol Cell. 1997 Dec . 1(1):3-11.

Insert

14-3-3 promoter (SFN Human)

Use

Tags

Expression

Bacterial

Mutation

Promoter

Available since

July 27, 2008

Availability

Academic Institutions and Nonprofits only
pGL3-PM-34a-K1/2

Plasmid

#25800

Depositor

Judy Lieberman

Article

Navarro et al Blood. 2009 Sep 3. 114(10):2181-92.

Insert

alternative hsa-miR-34a promoter

Use

Luciferase

Tags

luciferase

Expression

Mammalian

Mutation

Promoter

Available since

Aug. 9, 2010

Availability

Academic Institutions and Nonprofits only
psiCHECK2-AS34a

Plasmid

#37099

Depositor

Judy Lieberman

Article

Navarro et al Blood. 2009 Sep 3. 114(10):2181-92.

Insert

perfect complementary binding site for hsa-miR-34a (MIR34A Human)

Use

Luciferase

Tags

Expression

Mutation

Promoter

Available since

June 19, 2012

Availability

Academic Institutions and Nonprofits only
pDD2703

Plasmid

#175079

Purpose

Mammalian expression of Flag-tagged KSHV ORF45 E223A-S226A mutant

Depositor

Dirk Dittmer

Article

Alzhanova et al J Virol. 2021 Nov 9;95(23):e0145921. doi

Insert

KSHV ORF45 (ORF45 Kaposi's sarcoma-associated herpesvirus 8 )

Use

Tags

Expression

Mammalian

Mutation

E223A, S226A

Promoter

Available since

Feb. 8, 2022

Availability

Academic Institutions and Nonprofits only

Enlarge
pBK-CMV Pig10

Plasmid

#16504

Depositor

Bert Vogelstein

Article

Polyak et al Nature. 1997 Sep 18. 389(6648):300-5.

Insert

Pig10 (ENC1 Human)

Use

Tags

Expression

Mammalian

Mutation

Promoter

Available since

May 12, 2010

Availability

Academic Institutions and Nonprofits only
pHRCMV 14-3-3 sigma

Plasmid

#16552

Depositor

Bert Vogelstein

Article

Hermeking et al Mol Cell. 1997 Dec . 1(1):3-11.

Insert

14-3-3 sigma (SFN Human)

Use

Adenoviral

Tags

Expression

Mammalian

Mutation

Promoter

Available since

July 3, 2008

Availability

Academic Institutions and Nonprofits only
pRS314-MDM2

Plasmid

#18654

Depositor

Bert Vogelstein

Article

Oliner et al Nature. 1993 Apr 29. 362(6423):857-60.

Insert

MDM2 (MDM2 Human)

Use

Tags

Gal1 promoter

Expression

Yeast

Mutation

Promoter

Available since

June 20, 2008

Availability

Academic Institutions and Nonprofits only
p3004 pGEM E6-AP 76kD

Plasmid

#10857

Depositor

Peter Howley

Article

Huibregtse et al Mol Cell Biol 1993 Aug;13(8):4918-27.

Insert

E6-AP (UBE3A Human)

Use

Tags

Expression

Bacterial

Mutation

76kD: amino acids 213-865

Promoter

Available since

Oct. 26, 2005

Availability

Academic Institutions and Nonprofits only
p3012 pGEM E6-AP C-A

Plasmid

#8645

Depositor

Peter Howley

Article

Huibregtse et al Mol Cell Biol 1993 Aug;13(8):4918-27.

Insert

E6-AP (UBE3A Human)

Use

Tags

Expression

Bacterial

Mutation

active site cyteine codon mutated to encode alani…

Promoter

Available since

June 16, 2005

Availability

Academic Institutions and Nonprofits only
p3045 pVL E6-AP C-A

Plasmid

#8647

Depositor

Peter Howley

Article

Huibregtse et al Mol Cell Biol 1993 Aug;13(8):4918-27.

Insert

E6-AP (UBE3A Human)

Use

Tags

Expression

Insect

Mutation

Active site Cys mutated to encode Ala

Promoter

Available since

June 16, 2005

Availability

Academic Institutions and Nonprofits only
pDD2706

Plasmid

#175080

Purpose

Mammalian expression of Flag-tagged KSHV ORF45 RC mutant

Depositor

Dirk Dittmer

Article

Alzhanova et al J Virol. 2021 Nov 9;95(23):e0145921. doi

Insert

KSHV ORF45 (ORF45 Kaposi's sarcoma-associated herpesvirus 8)

Use

Tags

Expression

Mammalian

Mutation

RC mutant; sequence mutation: GCGGCCGCAGCGCA

Promoter

Available since

Feb. 8, 2022

Availability

Academic Institutions and Nonprofits only

Enlarge
pDD2708

Plasmid

#175081

Purpose

Mammalian expression of Flag-tagged KSHV ORF45 RN1 mutant

Depositor

Dirk Dittmer

Article

Alzhanova et al J Virol. 2021 Nov 9;95(23):e0145921. doi

Insert

KSHV ORF45 (ORF45 Kaposi's sarcoma-associated herpesvirus 8)

Use

Tags

Expression

Mammalian

Mutation

RN1 mutant: V284A/L285A

Promoter

Available since

Feb. 8, 2022

Availability

Academic Institutions and Nonprofits only

Enlarge
pDD2710

Plasmid

#175082

Purpose

Mammalian expression of Flag-tagged KSHV ORF45 RN2 mutant

Depositor

Dirk Dittmer

Article

Alzhanova et al J Virol. 2021 Nov 9;95(23):e0145921. doi

Insert

KSHV ORF45 (ORF45 Kaposi's sarcoma-associated herpesvirus 8)

Use

Tags

Expression

Mammalian

Mutation

RN2 mutant: I289A/L291A

Promoter

Available since

Feb. 8, 2022

Availability

Academic Institutions and Nonprofits only

Enlarge
NdeI – SacII – SpeI(NheI) - ANXA2 (29-339)

Plasmid

#136545

Purpose

Expresses ANXA2 chimeras in bacterial cells

Depositor

Laszlo Nyitray

Article

Ecsedi et al Structure. 2020 Aug 4;28(8):943-953.e4.

Type

Empty backbone

Use

Tags

ANXA2 (29-339) and His-tag

Expression

Bacterial

Mutation

Promoter

Available since

May 15, 2020

Availability

Academic Institutions and Nonprofits only

Enlarge
pLP-LNCX-PIK3CA-W11STOP

Plasmid

#25634

Depositor

Todd Waldman

Article

Kim et al Mol Cell Biol. 2007 Jan . 27(2):662-77.

Insert

PIK3CA (PIK3CA Human)

Use

Retroviral

Tags

FLAG

Expression

Mammalian

Mutation

Promoter

Available since

June 21, 2010

Availability

Academic Institutions and Nonprofits only
pcDNA3 MDM2 WT

Plasmid

#16233

Depositor

Mien-Chie Hung

Article

Zhou et al Nat Cell Biol. 2001 Nov . 3(11):973-82.

Insert

MDM2 (MDM2 Human)

Use

Tags

Expression

Mammalian

Mutation

Promoter

Available since

Nov. 30, 2007

Availability

Academic Institutions and Nonprofits only

Enlarge
G6PD/pRK5

Plasmid

#41521

Depositor

Xiaolu Yang

Article

Jiang et al Nat Cell Biol. 2011 Mar;13(3):310-6. Epu

Insert

glucose-6-phosphate dehydrogenase (G6PD Human)

Use

Tags

Expression

Mammalian

Mutation

Promoter

CMV

Available since

Jan. 14, 2013

Availability

Academic Institutions and Nonprofits only

Enlarge
pLenti_EF1a_Flag_EGFP

Plasmid

#183117

Purpose

Expresses flag-tagged EGFP in mammalian cells

Depositor

William Kaelin

Article

Stransky et al Proc Natl Acad Sci U S A. 2022 Apr 5;119

Insert

EGFP

Use

Lentiviral

Tags

Flag

Expression

Mammalian

Mutation

Promoter

EF1a

Available since

Aug. 24, 2022

Availability

Academic Institutions and Nonprofits only

Enlarge
pCI-MEG3

Plasmid

#44727

Depositor

Anne Klibanski

Article

Zhou et al J Biol Chem. 2007 Aug 24;282(34):24731-4

Insert

Maternally Expressed Gene 3 (MEG3 Human)

Use

Tags

Expression

Mammalian

Mutation

Promoter

CMV

Available since

May 3, 2013

Availability

Academic Institutions and Nonprofits only

Enlarge
pcDNA3.1/V5-His Snk/Plk2

Plasmid

#16015

Depositor

Wafik El-Deiry

Article

Burns et al Mol Cell Biol. 2003 Aug . 23(16):5556-71

Insert

Snk/Plk2 (PLK2 Human)

Use

Tags

V5-His

Expression

Mammalian

Mutation

Promoter

Available since

Nov. 2, 2007

Availability

Academic Institutions and Nonprofits only
pcDNA3-myc3-L11

Plasmid

#20936

Depositor

Yue Xiong

Article

Zhang et al Mol Cell Biol. 2003 Dec . 23(23):8902-12

Insert

Ribosomal protein L11 (RPL11 Human)

Use

Tags

myc3

Expression

Mammalian

Mutation

Promoter

Available since

April 28, 2009

Availability

Academic Institutions and Nonprofits only
GFP-LKB1

Plasmid

#21147

Depositor

Junying Yuan

Article

Karuman et al Mol Cell. 2001 Jun . 7(6):1307-19.

Insert

GFP-LKB1 (Stk11 Mouse)

Use

Tags

GFP

Expression

Mammalian

Mutation

Promoter

Available since

May 11, 2009

Availability

Academic Institutions and Nonprofits only
pLentiGuide_mCherry_sgEPAS1#1

Plasmid

#183122

Purpose

pLentiGuide modified to express mCherry and an sgRNA targeting EPAS1

Depositor

William Kaelin

Article

Stransky et al Proc Natl Acad Sci U S A. 2022 Apr 5;119

Insert

sgEPAS1-1

Use

Lentiviral

Tags

Expression

Mutation

Promoter

U6

Available since

Aug. 24, 2022

Availability

Academic Institutions and Nonprofits only

Enlarge
pcDNA3 V5 hHR23A

Plasmid

#13053

Depositor

Steven Grossman

Article

Brignone et al Oncogene. 2004 May 20. 23(23):4121-9.

Insert

hHR23A (RAD23A Human)

Use

Tags

His and V5

Expression

Mammalian

Mutation

R325K and L355P relative to NP_001257291.1

Promoter

Available since

Oct. 5, 2006

Availability

Academic Institutions and Nonprofits only

Enlarge
Flag-TRIM24ΔRING

Plasmid

#28140

Depositor

Michelle Barton

Article

Allton et al Proc Natl Acad Sci U S A. 2009 Jul 14. 1

Insert

TRIM24 (TRIM24 Human)

Use

Tags

FLAGX2

Expression

Mammalian

Mutation

Deletion of the RING domain: aa 1-139

Promoter

Available since

Feb. 10, 2012

Availability

Academic Institutions and Nonprofits only
pLentiCRISPR_Puro_sgAAVS1

Plasmid

#187818

Purpose

pLentiCRISPR that is selectable with puromycin with an sgRNA targeting AAVS1

Depositor

William Kaelin

Article

Stransky et al Proc Natl Acad Sci U S A. 2022 Apr 5;119

Insert

sgAAVS1

Use

CRISPR and Lentiviral

Tags

Expression

Mammalian

Mutation

Promoter

U6

Available since

Aug. 24, 2022

Availability

Academic Institutions and Nonprofits only

Enlarge

Showing: 451 - 500 of 1461 results

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