We narrowed to 3,117 results for: GAI

1. Lenti-sgCrebbp#2/Cre

   Plasmid

   #193210

   Purpose

   Lentiviral vector expressing Cre recombinase (driven by mPGK promoter) and an sgRNA against the mouse Crebbp gene

   Depositor

   Julien Sage

   Article

   Lee et al Cell Rep. 2023 Jan 13;42(1):111990. doi:

   Insert

   sgCrebbp#2 (Crebbp Mouse)
   

   Use

   CRISPR and Lentiviral

   Tags

   Expression

   Mammalian

   Mutation

   Promoter

   U6

   Available since

   Dec. 12, 2022

   Availability

   Academic Institutions and Nonprofits only

   

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2. FRIG-myc-Sema4D-CD4

   Plasmid

   #51606

   Purpose

   expresses myc-tagged Sema4D/CD4 non-cleavable chimera with extracellular Sema4D, intracellular CD4 in lentiviral backbone

   Depositor

   Suzanne Paradis

   Article

   Raissi et al Mol Cell Neurosci. 2013 Nov;57:23-32. do

   Insert

   Sema4D/CD4-FLAG (Sema4d Human, Mouse)
   

   Use

   Lentiviral

   Tags

   FLAG and myc

   Expression

   Mammalian

   Mutation

   Sema4D amino acids 660-861 were replaced with CD4…

   Promoter

   RSV

   Available since

   April 7, 2014

   Availability

   Academic Institutions and Nonprofits only

3. Lenti-sgCrebbp#1/Cre

   Plasmid

   #193209

   Purpose

   Lentiviral vector expressing Cre recombinase (driven by mPGK promoter) and an sgRNA against the mouse Crebbp gene

   Depositor

   Julien Sage

   Article

   Lee et al Cell Rep. 2023 Jan 13;42(1):111990. doi:

   Insert

   sgCrebbp#1 (Crebbp Mouse)
   

   Use

   CRISPR and Lentiviral

   Tags

   Expression

   Mammalian

   Mutation

   Promoter

   U6

   Available since

   Dec. 9, 2022

   Availability

   Academic Institutions and Nonprofits only

   

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4. pLKO-Tet-On-PLXNB2-shRNA1

   Plasmid

   #98399

   Purpose

   Lentivirus for expression of shRNA1 against human PLEXIN-B2 (Dox-inducible)

   Depositor

   Roland Friedel

   Article

   Junqueira Alves et al Nat Commun. 2021 Oct 14;12(1):6019. doi:

   Insert

   Plexin-B2 (PLXNB2 Human)
   

   Use

   Lentiviral

   Tags

   Expression

   Mutation

   Promoter

   Available since

   July 12, 2017

   Availability

   Academic Institutions and Nonprofits only

   

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5. pCENPTΔC-dCas9-3xGFP

   Plasmid

   #198325

   Purpose

   Expresses CENPTΔC-dCas9-3xGFP protein in mammalian cells. When coupled with a guide RNA against a high repeat target locus, this can be applied to seed ectopic kinetochores at the target locus

   Depositor

   Sarah McClelland

   Article

   Tovini et al EMBO J. 2023 May 15;42(10):e111587. doi:

   Insert

   CENPTΔC (CENPT Human)
   

   Use

   Lentiviral

   Tags

   EGFP x 3 and dCas9

   Expression

   Mammalian

   Mutation

   truncation - encodes only amino acids 1-375

   Promoter

   CMV-TetO

   Available since

   April 14, 2023

   Availability

   Academic Institutions and Nonprofits only

   

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6. CDK16 gRNA (BRDN0001147125)

   Plasmid

   #76903

   Purpose

   3rd generation lentiviral gRNA plasmid targeting human CDK16

   Depositor

   John Doench, David Root

   Article

   Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

   Insert

   CDK16 (CDK16 Human)
   

   Use

   CRISPR and Lentiviral

   Tags

   Expression

   Mammalian

   Mutation

   Promoter

   hU6

   Available since

   July 6, 2016

   Availability

   Academic Institutions and Nonprofits only

   

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7. CDK16 gRNA (BRDN0001146694)

   Plasmid

   #76901

   Purpose

   3rd generation lentiviral gRNA plasmid targeting human CDK16

   Depositor

   John Doench, David Root

   Article

   Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

   Insert

   CDK16 (CDK16 Human)
   

   Use

   CRISPR and Lentiviral

   Tags

   Expression

   Mammalian

   Mutation

   Promoter

   hU6

   Available since

   July 6, 2016

   Availability

   Academic Institutions and Nonprofits only

   

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8. CDK16 gRNA (BRDN0001147123)

   Plasmid

   #76902

   Purpose

   3rd generation lentiviral gRNA plasmid targeting human CDK16

   Depositor

   John Doench, David Root

   Article

   Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

   Insert

   CDK16 (CDK16 Human)
   

   Use

   CRISPR and Lentiviral

   Tags

   Expression

   Mammalian

   Mutation

   Promoter

   hU6

   Available since

   July 6, 2016

   Availability

   Academic Institutions and Nonprofits only

   

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9. pLKO.1.shCDK8

   Plasmid

   #19760

   Depositor

   William Hahn

   Article

   Firestein et al Nature. 2008 Sep 25. 455(7212):547-51.

   Insert

   small hairpin RNA against CDK8 (CDK8 Human)
   

   Use

   Lentiviral and RNAi

   Tags

   Expression

   Mammalian

   Mutation

   Promoter

   Available since

   Oct. 27, 2008

   Availability

   Academic Institutions and Nonprofits only

10. pCAG-eSpCas9-2A-GFP-sgRNA-HSD17B11

    Plasmid

    #161923

    Purpose

    To generate HSD17B11 KO in human cells. Co-expresses eSpCas9(1.1), GFP and a guide RNA against HSD17B11 exon 1.

    Depositor

    Sébastien Britton

    Article

    Demange et al Elife. 2022 May 10;11. pii: 73913. doi:

    Insert

    sgRNA targeting HSD17B11 exon 1
    

    Use

    CRISPR

    Tags

    Expression

    Mutation

    Promoter

    U6

    Available since

    May 12, 2022

    Availability

    Academic Institutions and Nonprofits only

    

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11. Lenti-sgHcn1#2/Cre

    Plasmid

    #193218

    Purpose

    Lentiviral vector expressing Cre recombinase (driven by mPGK promoter) and an sgRNA against the mouse Hcn1 gene

    Depositor

    Julien Sage

    Article

    Lee et al Cell Rep. 2023 Jan 13;42(1):111990. doi:

    Insert

    sgHcn1#2 (Hcn1 Mouse)
    

    Use

    CRISPR and Lentiviral

    Tags

    Expression

    Mammalian

    Mutation

    Promoter

    U6

    Available since

    Dec. 9, 2022

    Availability

    Academic Institutions and Nonprofits only

    

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12. pCMV-TNT-CFP-STIM1-C227W

    Plasmid

    #68403

    Purpose

    Expresses a STIM1 gain-of-function mutant in mammalian cells

    Depositor

    Yubin Zhou

    Article

    Ma et al Nat Commun. 2015 Jul 17;6:7826. doi: 10.

    Insert

    CFP-STIM1 (STIM1 Human)
    

    Use

    Tags

    Cyan Fluorescent Protein (CFP)

    Expression

    Mammalian

    Mutation

    Changed Cysteine 227 to Tryptophan; CFP was inser…

    Promoter

    CMV

    Available since

    Nov. 13, 2015

    Availability

    Academic Institutions and Nonprofits only

13. pLKO-Tet-On-PLXNB2-shRNA2

    Plasmid

    #98400

    Purpose

    Lentivirus for expression of shRNA2 against human PLEXIN-B2 (Dox-inducible)

    Depositor

    Roland Friedel

    Article

    Junqueira Alves et al Nat Commun. 2021 Oct 14;12(1):6019. doi:

    Insert

    Plexin-B2 (PLXNB2 Human)
    

    Use

    Lentiviral

    Tags

    Expression

    Mutation

    Promoter

    Available since

    July 12, 2017

    Availability

    Academic Institutions and Nonprofits only

    

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14. pLKO.1-shDnd1-No7

    Plasmid

    #70068

    Purpose

    TRC lentiviral vector for shRNA against mouse Dnd1 #7

    Depositor

    Thomas Tuschl

    Article

    Yamaji et al Nature. 2017 Mar 23;543(7646):568-572. d

    Insert

    Dnd1 (Dnd1 Mouse)
    

    Use

    Lentiviral

    Tags

    Expression

    Mammalian

    Mutation

    Promoter

    EF1alpha

    Available since

    Nov. 22, 2017

    Availability

    Academic Institutions and Nonprofits only

15. pcDNA3.2-Cx43-M100/125/147/213-siResist

    Plasmid

    #49858

    Purpose

    Encodes human connexin 43 with M100, M125, M147, and M213 mutated to L and wobble mutations conferring resistance against an siRNA

    Depositor

    Robin Shaw

    Article

    Smyth et al Cell Rep. 2013 Nov 5. pii: S2211-1247(13

    Insert

    Connexin 43 (GJA1 Human)
    

    Use

    Tags

    Expression

    Mammalian

    Mutation

    Methionine100, Methionine 125, Methionine 147, an…

    Promoter

    CMV

    Available since

    Dec. 20, 2013

    Availability

    Academic Institutions and Nonprofits only

16. pENTR221-ITGB1(no stop)

    Plasmid

    #215453

    Purpose

    Gateway entry vector with integrin beta1 wild-type (WT) without a stop codon

    Depositor

    Johanna Ivaska

    Article

    Conway et al Nat Cell Biol. 2025 May 26. doi: 10.1038

    Insert

    ITGB1 (ITGB1 Human)
    

    Use

    Gateway entry vector

    Tags

    Expression

    Mutation

    Silent mutations added to disrupt shRNA binding a…

    Promoter

    none

    Available since

    Sept. 4, 2025

    Availability

    Industry, Academic Institutions, and Nonprofits

    

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17. pHD-sfGFP-ScarlessDsRed-GMR-eya(shRNA)

    Plasmid

    #240228

    Purpose

    Parental donor plasmid for scarless sfGFP-fusion knock-in fly lines. Red fluorescent fly eye marker to select for knock-in events, small fly eye marker to select against backbone integration.

    Depositor

    Norbert Perrimon, Justin Bosch

    Article

    Bosch et al bioRxiv 2025.07.09.659702; doi: https://

    Type

    Empty backbone

    Use

    CRISPR

    Tags

    Expression

    Insect

    Mutation

    Promoter

    Available since

    July 11, 2025

    Availability

    Academic Institutions and Nonprofits only

    

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18. pHD-T2A-Gal4-3xP3DsRed-GMR-eya(shRNA)

    Plasmid

    #240229

    Purpose

    Parental donor plasmid for T2A-Gal4 knock-in fly lines. Red fluorescent fly eye marker to select for knock-in events, small fly eye marker to select against backbone integration.

    Depositor

    Norbert Perrimon, Justin Bosch

    Article

    Bosch et al bioRxiv 2025.07.09.659702; doi: https://

    Type

    Empty backbone

    Use

    CRISPR

    Tags

    Expression

    Insect

    Mutation

    Promoter

    Available since

    July 11, 2025

    Availability

    Academic Institutions and Nonprofits only

    

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19. pENTR2b-ITGB1(YYFF)

    Plasmid

    #215451

    Purpose

    Gateway entry vector with integrin beta1 NPxY mutant (YYFF)

    Depositor

    Johanna Ivaska

    Article

    Conway et al Nat Cell Biol. 2025 May 26. doi: 10.1038

    Insert

    ITGB1 (ITGB1 Human)
    

    Use

    Gateway entry vector

    Tags

    Expression

    Mutation

    Mutations in the NPxY sites Y783F, Y795F; Silent …

    Promoter

    none

    Available since

    May 29, 2025

    Availability

    Industry, Academic Institutions, and Nonprofits

    

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20. pENTR2b-ITGB1(WT)-mRuby2

    Plasmid

    #215446

    Purpose

    Gateway entry vector with integrin beta1 tagged with mRuby2

    Depositor

    Johanna Ivaska

    Article

    Conway et al Nat Cell Biol. 2025 May 26. doi: 10.1038

    Insert

    ITGB1 (ITGB1 Human)
    

    Use

    Gateway entry vector

    Tags

    mRuby2

    Expression

    Mutation

    Silent mutations added to disrupt shRNA binding a…

    Promoter

    none

    Available since

    May 29, 2025

    Availability

    Industry, Academic Institutions, and Nonprofits

    

    Enlarge