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pEN_TTmiRc2_BirA_NRF2
Plasmid#136524PurposeUsed as a donor vector to clone into pSLIKDepositorInsertNRF2 (NFE2L2 Human)
UseEntry vector for gateway cloningTagsExpressionMutationPromoterAvailable sinceAvailabilityAcademic Institutions and Nonprofits only -
GSE22 T329A in pENTR1A (w187-1)
Plasmid#22253DepositorInsertGenetic suppressor element #22, T329A
UseEntry vectorTagsExpressionMutationThreonine 329 is mutated to Alanine (p53 nomencat…PromoterAvailable sinceDec. 17, 2009AvailabilityAcademic Institutions and Nonprofits only -
pcDNA3.1(+)Flag-His-ATM wt
Plasmid#31985PurposeMammalian expression of human ATM with Flag and His tagsDepositorInsertATM wild-type (ATM Human)
UseTagsFlag and HISExpressionMammalianMutation3' UTR of 400 nucl.PromoterAvailable sinceSept. 19, 2011AvailabilityAcademic Institutions and Nonprofits only -
pLPC-Progerin
Plasmid#69061Purposeencodes the lamin A mutant with a 50 amino acids deletion responsible for the Hutchinson-Gilford Progeria SyndromeDepositorInsertProgerin (LMNA Human)
UseRetroviralTagsExpressionMammalianMutationPromoterCMVAvailable sinceDec. 15, 2015AvailabilityAcademic Institutions and Nonprofits only -
pcDNA3.1(+) Flag-His-ATM kd
Plasmid#31986DepositorInsertATM kd (ATM Human)
UseTagsFlag and HisExpressionMammalianMutation3'UTRf 9 nucl/D2870A N2875k. catalytically …PromoterAvailable sinceMarch 12, 2012AvailabilityAcademic Institutions and Nonprofits only -
pSLIK_hygro_BirA_NRF2
Plasmid#136539PurposeLentiviral expression vector for an inducible BirA-NRF2DepositorInsertBirA-NRF2 (NFE2L2 Human)
UseLentiviral; Destination vector for gateway cloningTagsExpressionMammalianMutationPromoterAvailable sinceJune 6, 2020AvailabilityAcademic Institutions and Nonprofits only -
pEF_PE2
Plasmid#199267PurposeMammalian expression of SpCas9 prime editor 2 under EF1α promoterDepositorInsertPE2-P2A-mp53DD
UseTagsExpressionMammalianMutationΔ40-903PromoterAvailable sinceApril 13, 2023AvailabilityAcademic Institutions and Nonprofits only -
pBABE_hygro_mRFP1_NRF2
Plasmid#136579Purposemammalian expression of mRFP1-tagged human NRF2DepositorInsertNRF2 (NFE2L2 Human)
UseRetroviralTagsN-mRFP1-FLAGExpressionMammalianMutationPromoterAvailable sinceJuly 14, 2020AvailabilityAcademic Institutions and Nonprofits only -
pLPC-S22A-Progerin
Plasmid#69065Purposeencodes a Progerin mutant where serine 22 is mutated to an alanineDepositorInsertProgerin (LMNA Human)
UseRetroviralTagsExpressionMammalianMutationProgerin with serine 22 mutated to alaninePromoterCMVAvailable sinceDec. 17, 2015AvailabilityAcademic Institutions and Nonprofits only -
pLPC-Flag-SOCS1
Plasmid#129514PurposeRetroviral vector for the expression of human SOCS1 with a FLAG tag in N-terminalDepositorInsertSOCS1 (SOCS1 Human)
UseRetroviralTagsFlagExpressionMammalianMutationPromoterCMVAvailable sinceSept. 24, 2019AvailabilityAcademic Institutions and Nonprofits only -
tet_pLKO.1_puro_shNRF2 #1
Plasmid#136584PurposeExpresses an inducible short hairpin targeting human NRF2 sequenceDepositorInsertshNRF2v1 (NFE2L2 Human)
UseLentiviralTagsExpressionMammalianMutationPromoterAvailable sinceJune 13, 2020AvailabilityAcademic Institutions and Nonprofits only -
pGL3-IRES-miR34a-P2
Plasmid#64786PurposeLuciferase expression driven by miR-34a promoter P2DepositorInsertmiR-34a promoter P2 (MIR34A Human)
UseLuciferaseTagsExpressionMutationPromoterAvailable sinceJuly 17, 2015AvailabilityAcademic Institutions and Nonprofits only -
pCIneoMyc UNC119B
Plasmid#128333PurposeMammalian expression vector of Myc-tagged human UNC119BDepositorInsertUNC119B (UNC119B Human)
UseTagsMycExpressionMammalianMutationPromoterCMVAvailable sinceOct. 12, 2019AvailabilityAcademic Institutions and Nonprofits only -
tet_pLKO.1_puro_shNRF2 #2
Plasmid#136585PurposeExpresses an inducible short hairpin targeting human NRF2 sequenceDepositorInsertshNRF2v2 (NFE2L2 Human)
UseLentiviralTagsExpressionMammalianMutationPromoterAvailable sinceJune 13, 2020AvailabilityAcademic Institutions and Nonprofits only -
pCIneoMyc UNC119Aa
Plasmid#128331PurposeMammalian expression vector of Myc-tagged human UNC119A isoform aDepositorInsertUNC119 (UNC119 Human)
UseTagsMycExpressionMammalianMutationPromoterCMVAvailable sinceJuly 1, 2020AvailabilityAcademic Institutions and Nonprofits only -
pCIneoMyc UNC119Ab
Plasmid#128332PurposeMammalian expression vector of Myc-tagged human UNC119A isoform bDepositorInsertUNC119 (UNC119 Human)
UseTagsMycExpressionMammalianMutationPromoterCMVAvailable sinceOct. 29, 2020AvailabilityAcademic Institutions and Nonprofits only -
pICE-HA-Ku70-siR-WT
Plasmid#82329PurposePlasmid for constitutive or doxycycline-inducible expression of wild-type human Ku70 resistant to a siRNA. Confers resistance to puromycin. Use T-REx cells for doxycycline-inducible expression.DepositorInsertKu70 (XRCC6 Human)
UseTagsHAExpressionMammalianMutationPromoterCMV-tetAvailable sinceSept. 13, 2016AvailabilityAcademic Institutions and Nonprofits only -
pSLIK_neo_3xflag_CHEK2
Plasmid#136536PurposeLentiviral expression vector for an inducible 3xflag-tagged CHEK2DepositorInsertCHEK2 (CHEK2 Human)
UseLentiviral; Destinatioin vector for gateway cloni…Tags3x FLAGExpressionMammalianMutationPromoterAvailable sinceJune 20, 2020AvailabilityAcademic Institutions and Nonprofits only -
pLPC-Progerin-CS
Plasmid#69064Purposeencodes Progerin with a substitution of cysteine in CaaX-motif by a serineDepositorInsertProgerin (LMNA Human)
UseRetroviralTagsExpressionMammalianMutationProgerin with substitution of cysteine in CaaX-mo…PromoterCMVAvailable sinceDec. 17, 2015AvailabilityAcademic Institutions and Nonprofits only -
pLPC-S22A-LaminA
Plasmid#69066Purposeencodes a mutant lamin A where serine 22 is mutated to a an alanineDepositorInsertLaminA (LMNA Human)
UseRetroviralTagsExpressionMammalianMutationserine 22 mutated in alaninePromoterCMVAvailable sinceDec. 17, 2015AvailabilityAcademic Institutions and Nonprofits only -
pEN_TTmiRc2_3xflag_NRF2
Plasmid#136527PurposeUsed as a donor vector containing N-term 3xFLAG to clone into pSLIKDepositorInsertNRF2 (NFE2L2 Human)
UseEntry vector for gateway cloningTags3x FLAGExpressionMutationPromoterAvailable sinceOct. 4, 2023AvailabilityAcademic Institutions and Nonprofits only -
pCMV-myc3-Mdm2 D367A
Plasmid#52058Purposeexpression of non-cleavable Mdm2 in mammalian cellsDepositorInsertMdm2 D367A (MDM2 Human)
UseTagsmyc3ExpressionMammalianMutationD367APromoterCMVAvailable sinceMarch 13, 2014AvailabilityAcademic Institutions and Nonprofits only -
pAc-GFP-dSUMO
Plasmid#85696Purposeexpression of GFP-SUMO1 in Drosophila cellsDepositorInsertSUMO (Sumo Fly)
UseTagsGFPExpressionInsectMutationPromoterAc5Available sinceMarch 21, 2017AvailabilityAcademic Institutions and Nonprofits only -
pSLIK_hygro_BirA_CDKN1A
Plasmid#136538PurposeLentiviral expression vector for an inducible BirA-CDKN1ADepositorInsertBirA-CDKN1A (CDKN1A )
UseLentiviral; Destinatioin vector for gateway cloni…TagsExpressionMammalianMutationPromoterAvailable sinceJune 13, 2024AvailabilityAcademic Institutions and Nonprofits only -
pCMV-myc3-Mdm2 p60
Plasmid#52059Purposeexpression of truncated Mdm2 in mammalian cellsDepositorInsertMdm2 p60 (truncated) (MDM2 Human)
UseTagsmyc3ExpressionMammalianMutationp60 (truncated at D367, DVDP motif)PromoterCMVAvailable sinceMarch 20, 2014AvailabilityAcademic Institutions and Nonprofits only -
pLPC-L647RLaminA
Plasmid#69060Purposeencodes a lamin A mutant with Leucine 647 mutated to an ArgininDepositorInsertLaminA (LMNA Human)
UseRetroviralTagsExpressionMammalianMutationLamin A with Leucine 647 mutated to ArgininePromoterCMVAvailable sinceDec. 15, 2015AvailabilityAcademic Institutions and Nonprofits only -
pLVXT-mTcf3
Plasmid#121935Purposedoxycycline-inducible mouse Tcf3DepositorInsertTranscription Factor 3 (Tcf3 Mouse)
UseTagsExpressionMutationPromoterAvailable sinceFeb. 21, 2019AvailabilityAcademic Institutions and Nonprofits only -
pGLS3-5xHRE-PHLDA3(wt)
Plasmid#72557PurposeHypoxia induced mutant PHLDA3. Contains the HRE from VEGF sequence (5 repeats) upstream of PHLDA3.DepositorInsertPHLDA3 (PHLDA3 Human)
UseTags5XHREExpressionMammalianMutationPromoterE1b minimalAvailable sinceApril 12, 2017AvailabilityAcademic Institutions and Nonprofits only -
TRRAP sgRNA1
Plasmid#138182Purpose3rd generation lentiviral gRNA plasmid targeting human TRRAPDepositorInsertTRRAP (TRRAP Human)
UseCRISPR and LentiviralTagsExpressionMammalianMutationPromoterU6Available sinceMarch 18, 2020AvailabilityAcademic Institutions and Nonprofits only -
TRRAP sgRNA3
Plasmid#138184Purpose3rd generation lentiviral gRNA plasmid targeting human TRRAPDepositorInsertTRRAP (TRRAP Human)
UseCRISPR and LentiviralTagsExpressionMammalianMutationPromoterU6Available sinceMarch 18, 2020AvailabilityAcademic Institutions and Nonprofits only -
TRRAP sgRNA2
Plasmid#138183Purpose3rd generation lentiviral gRNA plasmid targeting human TRRAPDepositorInsertTRRAP (TRRAP Human)
UseCRISPR and LentiviralTagsExpressionMammalianMutationPromoterU6Available sinceMarch 18, 2020AvailabilityAcademic Institutions and Nonprofits only -
Px458-Cas9n-Trp63-Exon4-1sgRNA
Plasmid#88848PurposeCRISPR KO of Trp63DepositorInsertTrp63 (Trp63 Mouse)
UseCRISPRTagsExpressionMammalianMutationPromoterAvailable sinceJuly 11, 2017AvailabilityAcademic Institutions and Nonprofits only -
MSCV-miR-34b/34c
Plasmid#63933PurposeMSCV vector for overexpressing mouse miR-34b/34cDepositorUseTagsExpressionMammalianMutationPromoterAvailable sinceJune 19, 2015AvailabilityAcademic Institutions and Nonprofits only -
pCMV-myc3-Mdm2 D367E
Plasmid#52057Purposeexpression of non-cleavable Mdm2 in mammalian cellsDepositorInsertMdm2 D367E (MDM2 Human)
UseTagsmyc3ExpressionMammalianMutationD367EPromoterCMVAvailable sinceMarch 13, 2014AvailabilityAcademic Institutions and Nonprofits only -
tet-pLKO.1_puro_shJUND #1
Plasmid#136581PurposeExpresses an inducible short hairpin targeting human JUND sequenceDepositorInsertshJUNDv1 (JUND Human)
UseLentiviralTagsExpressionMammalianMutationPromoterAvailable sinceJan. 5, 2023AvailabilityAcademic Institutions and Nonprofits only -
pLPC-L647RLaminA-CS
Plasmid#69062Purposeencodes a lamin A mutant with Leucine 647 mutated to an Arginin and with a substitution of cysteine in CaaX-motif by a serineDepositorInsertLaminA (LMNA Human)
UseRetroviralTagsExpressionMammalianMutationLamin A with Leucine 647 mutated to Arginine and …PromoterCMVAvailable sinceDec. 17, 2015AvailabilityAcademic Institutions and Nonprofits only -
Px458-Cas9n-Trp63-Exon4-2sgRNA
Plasmid#88849PurposeCRISPR KO of Trp63DepositorInsertTrp63 (Trp63 Mouse)
UseCRISPRTagsExpressionMammalianMutationPromoterAvailable sinceJuly 11, 2017AvailabilityAcademic Institutions and Nonprofits only -
pEN_TTmiRc2_BirA_CDKN1A
Plasmid#136523PurposeUsed as a donor vector to clone into pSLIKDepositorInsertCDKN1A (CDKN1A Human)
UseEntry vector for gateway cloningTagsExpressionMutationPromoterAvailable sinceJuly 28, 2021AvailabilityAcademic Institutions and Nonprofits only -
pGL3-CMV-Cdc42 3'UTR mutant (position 577-599)
Plasmid#51391DepositorInsertNM_001039802.1 (CDC42 Human)
UseLuciferaseTagsLuciferaseExpressionMutationmiR-29 binding site mutant (position 577-599)PromoterCMVAvailable sinceMarch 31, 2014AvailabilityAcademic Institutions and Nonprofits only -
pSFG-TFII-I-GFP Y248&249F
Plasmid#22196DepositorInsertTFII-I (GTF2I Human)
UseRetroviralTagsGFPExpressionMammalianMutationChanged Tyrosines 248 and 249 to Phenylalanines. …PromoterAvailable sinceNov. 13, 2009AvailabilityAcademic Institutions and Nonprofits only -
pCEP-WAF1-ES
Plasmid#16449DepositorInsertWAF1 stop codon mut (CDKN1A Human)
UseTagsExpressionMammalianMutationstop codon at amino acid 49 instead of tryptophan…PromoterAvailable sinceApril 7, 2008AvailabilityAcademic Institutions and Nonprofits only -
Px458-Cas9n-Trp73-Exon4-3sgRNA
Plasmid#88850PurposeCRISPR KO of Trp73DepositorInsertTrp73 (Trp73 Mouse)
UseCRISPRTagsExpressionMammalianMutationPromoterAvailable sinceJuly 11, 2017AvailabilityAcademic Institutions and Nonprofits only -
Px458-Cas9n-Trp73-Exon4-4sgRNA
Plasmid#88851PurposeCRISPR KO of Trp73DepositorInsertTrp73 (Trp73 Mouse)
UseCRISPRTagsExpressionMammalianMutationPromoterAvailable sinceJuly 11, 2017AvailabilityAcademic Institutions and Nonprofits only -
pGL3-CMV-Cdc42 3'UTR mutant (position 577-599 and 997-1019)
Plasmid#51390DepositorInsertNM_001039802.1 (CDC42 Human)
UseLuciferaseTagsLuciferaseExpressionMutationmiR-29 binding site mutant (position 577-599, 997…PromoterCMVAvailable sinceMarch 31, 2014AvailabilityAcademic Institutions and Nonprofits only -
pCAG-EGxxFP-CD55
Plasmid#153959PurposeUsed for EGxxFP assay with CD55 intron 3, exon 4, and intron 4 sequencesDepositorInsertCD55 (a 1,016-bp fragment from intron 3, exon 4, and intron 4)
UseA plasmid specific for egxxfp assayTagsN/AExpressionMammalianMutationNo mutationPromoterCAG promoterAvailable sinceDec. 9, 2020AvailabilityAcademic Institutions and Nonprofits only -
prCOrev
Plasmid#153961PurposeUsed to detect crossover-type DNA recombination events elicited by iso-positional nicking of two homologous DNA fragments (recombination analogous to Holliday's model)DepositorInsert5' and 3' EGFP fragments sharing a 386-bp sequence, separated by a NeoR gene cassette and arranged in the opposite direction
UseRetroviral; A reporter plasmid detecting dna reco…TagsNLS-ZFExpressionMammalianMutationNo mutationPromoterLTRAvailable sinceOct. 22, 2020AvailabilityAcademic Institutions and Nonprofits only -
prCO
Plasmid#153960PurposeUsed to detect crossover-type DNA recombination events elicited by iso-positional nicking of two homologous DNA fragments (recombination analogous to Holliday's model)DepositorInsert5' and 3' EGFP fragments sharing a 386-bp sequence, separated by a NeoR gene cassette and arranged in the same direction
UseRetroviral; A reporter plasmid detecting dna reco…TagsNLS-ZFExpressionMammalianMutationNo mutationPromoterLTRAvailable sinceOct. 22, 2020AvailabilityAcademic Institutions and Nonprofits only -
pLPC-Flag-SOCS1-Y80D
Plasmid#129516PurposeRetroviral vector for the expression of human SOCS1 with a Y80D mutation and a FLAG tag in N-terminalDepositorInsertSOCS1 (SOCS1 Human)
UseRetroviralTagsFlagExpressionMammalianMutationChanged Tyrosine 80 to Aspartic acidPromoterCMVAvailable sinceSept. 24, 2019AvailabilityAcademic Institutions and Nonprofits only -
pLPC-Flag-SOCS1-Y80F
Plasmid#129517PurposeRetroviral vector for the expression of human SOCS1 with a Y80F mutation and a FLAG tag in N-terminalDepositorInsertSOCS1 (SOCS1 Human)
UseRetroviralTagsFlagExpressionMammalianMutationChanged Tyrosine 80 to PhenylalaninePromotercmvAvailable sinceSept. 24, 2019AvailabilityAcademic Institutions and Nonprofits only
