375 results

1. Human CRISPRa sgRNA library Calabrese in backbone XPR_502 (P65 HSF)

   Pooled Library

   #1000000111

   Purpose

   Genome-wide CRISPR gRNA pooled library for activation of human genes

   Depositor

   David Root, John Doench

   Available since

   Aug. 3, 2017

   Availability

   Academic Institutions and Nonprofits only

2. Human Epigenetic Knockout Library

   Pooled Library

   #162256

   Purpose

   Lentiviral CRISPR library targets human epigenetic genes

   Depositor

   Kivanc Birsoy

   Article

   Williams et al Cell Metab. 2020 Apr 7;31(4):852-861.e6.

   Expression

   Mammalian

   Species

   Homo sapiens

   Use

   CRISPR and Lentiviral

   Available since

   Nov. 17, 2020

   Availability

   Academic Institutions and Nonprofits only

3. PB-EF1a-Puro-V8.2

   Pooled Library

   #178943

   Purpose

   Barcoding library for the macsGESTALT inducible lineage recording system

   Depositor

   Christopher Lengner

   Article

   Simeonov et al Cancer Cell. 2021 Aug 9;39(8):1150-1162.

   Expression

   Mammalian

   Available since

   March 22, 2022

   Availability

   Academic Institutions and Nonprofits only

4. Mouse sgRNA library Brie in lentiCRISPRv2

   Pooled Library

   #73632

   Purpose

   Mouse sgRNA library in backbone lentiCRISPRv2 containing 78,637 unique sgRNAs targeting 19,674 genes along with 1000 non-targeting controls

   Depositor

   David Root, John Doench

   Article

   Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

   Expression

   Mammalian

   Use

   CRISPR and Lentiviral

   Available since

   Feb. 25, 2016

   Availability

   Academic Institutions and Nonprofits only

5. Mini-human AsCpf1-based human genome-wide knockout library

   Pooled Library

   #130630

   Purpose

   Expresses crRNAs for genome-wide knockout pooled library screening

   Depositor

   Giulio Draetta

   Article

   Liu et al Nat Commun. 2019 Jul 17;10(1):3144. doi:

   Expression

   Mammalian

   Species

   Homo sapiens

   Use

   CRISPR and Lentiviral

   Available since

   Sept. 9, 2019

   Availability

   Academic Institutions and Nonprofits only

6. hCRISPRi-v2, genome-wide, top 5 sgRNAs/gene

   Pooled Library

   #83969

   Purpose

   Version 2 of the human CRISPRi genome wide library

   Depositor

   Jonathan Weissman

   Article

   Horlbeck et al Elife. 2016 Sep 23;5. pii: e19760. doi:

   Use

   Lentiviral

   Available since

   Nov. 15, 2016

   Availability

   Academic Institutions and Nonprofits only

7. pSMAL-CellTag-V1

   Pooled Library

   #115643

   Purpose

   Viral barcoding library to combinatorially index cells for single-cell analysis of clonal dynamics

   Depositor

   Samantha Morris

   Article

   Biddy et al Nature. 2018 Dec;564(7735):219-224. doi:

   Has Service

   Concentrated Lentiviral Prep

   Expression

   Mammalian

   Species

   Synthetic

   Use

   Lentiviral

   Available since

   Dec. 5, 2018

   Availability

   Academic Institutions and Nonprofits only

8. Human sgRNA library Gattinara in pRDA_118 backbone

   Pooled Library

   #136986

   Purpose

   Expresses sgRNAs targeting human genes

   Depositor

   John Doench

   Article

   DeWeirdt et al Nat Commun. 2020 Feb 6;11(1):752. doi: 1

   Expression

   Mammalian

   Species

   Homo sapiens

   Use

   CRISPR and Lentiviral

   Available since

   Feb. 24, 2020

   Availability

   Academic Institutions and Nonprofits only

9. Mouse CRISPRa sgRNA library Caprano in backbone XPR_502 (P65 HSF)

   Pooled Library

   #1000000113

   Purpose

   Genome-wide CRISPR gRNA pooled library for activation of mouse genes

   Depositor

   David Root, John Doench

   Available since

   July 13, 2018

   Availability

   Academic Institutions and Nonprofits only

10. Mouse CRISPRi sgRNA library Dolomiti in backbone XPR_050

    Pooled Library

    #1000000131

    Purpose

    Genome-wide CRISPR gRNA pooled library for inhibition of mouse genes

    Depositor

    David Root, John Doench

    Available since

    July 13, 2018

    Availability

    Academic Institutions and Nonprofits only

11. Human GeCKO Lentiviral sgRNA Library v2 (LentiCRISPR)

    Pooled Library

    #1000000048

    Purpose

    CRISPR gRNA knockout pooled library for targeting the human genome

    Depositor

    Feng Zhang

    Available since

    May 8, 2014

    Availability

    Academic Institutions and Nonprofits only

12. Membrane protein gRNA library

    Pooled Library

    #113345

    Purpose

    Contains 58,071 gRNAs targeting 6,213 membrane proteins and 500 non-targeting gRNAs

    Depositor

    Gavin Wright

    Article

    Chong et al Genome Biol. 2018 Nov 26;19(1):205. doi:

    Species

    Homo sapiens

    Use

    Lentiviral

    Available since

    Jan. 4, 2019

    Availability

    Academic Institutions and Nonprofits only

13. Mouse Cherry Brie Pooled Library

    Pooled Library

    #170511

    Purpose

    CRISPR library targeting mouse genes

    Depositor

    Pavel Tolar

    Article

    Newman et al biorXiv 2021.03.02.433398

    Expression

    Mammalian

    Species

    Synthetic

    Use

    CRISPR and Lentiviral

    Available since

    Sept. 9, 2021

    Availability

    Academic Institutions and Nonprofits only

14. pMSCV-U6gRNA(lib)-PGKpuroT2ABFP library

    Pooled Library

    #104861

    Depositor

    Sarah Teichmann

    Article

    Henriksson et al Cell. 2019 Jan 7. pii: S0092-8674(18)315

    Available since

    Sept. 9, 2019

    Availability

    Academic Institutions and Nonprofits only

15. Bassik lab Mouse CRISPR-Cas9 Deletion Library - Membrane proteins

    Pooled Library

    #1000000124

    Purpose

    CRISPR gRNA mouse knockout pooled library - Membrane proteins

    Depositor

    Michael Bassik

    Available since

    May 23, 2018

    Availability

    Academic Institutions and Nonprofits only

16. Human CRISPR Metabolic Gene Knockout Library

    Pooled Library

    #110066

    Purpose

    Encodes gRNAs for targeting metabolic genes in CRISPR screens.

    Depositor

    David Sabatini

    Article

    Birsoy et al Cell. 2015 Jul 30;162(3):540-51. doi: 10

    Use

    Lentiviral

    Available since

    May 4, 2018

    Availability

    Academic Institutions and Nonprofits only

17. TRE-MPRA_minCMV Library

    Pooled Library

    #201012

    Purpose

    Massively parallel reporter assay (MPRA) library with minCMV promoter

    Depositor

    Justin English

    Article

    Zahm et al bioRxiv. 2023 May 11:2023.05.11.539703.

    Expression

    Mammalian

    Use

    Luciferase

    Available since

    Oct. 31, 2023

    Availability

    Academic Institutions and Nonprofits only

18. Self-targeting epegRNA library, +5 G>H (lDS004)

    Pooled Library

    #227707

    Purpose

    CRISPR guide RNA library for prime editing

    Depositor

    Brittany Adamson

    Article

    Cirincione et al Nat Methods. 2024 Nov 19. doi: 10.1038/s

    Expression

    Mammalian

    Use

    Lentiviral

    Available since

    Jan. 23, 2025

    Availability

    Academic Institutions and Nonprofits only

19. Glycogene CRISPR Library

    Pooled Library

    #140961

    Purpose

    Targets human genes involved in cellular glycosylation.

    Depositor

    Sriram Neelamegham

    Article

    Zhu et al Glycobiology. 2020 Aug 8. pii: 5889976.

    Species

    Homo sapiens

    Use

    CRISPR and Lentiviral

    Available since

    Sept. 9, 2020

    Availability

    Academic Institutions and Nonprofits only

20. Drosophila_sgRNA_group_2

    Pooled Library

    #134583

    Purpose

    Targets Drosophila orthologs of vertebrate genes that have undergone expansion in the vertebrate line

    Depositor

    Norbert Perrimon

    Article

    Viswanatha et al Elife. 2018 Jul 27;7. pii: 36333. doi: 1

    Expression

    Insect

    Species

    Drosophila melanogaster

    Use

    CRISPR

    Available since

    Feb. 25, 2020

    Availability

    Academic Institutions and Nonprofits only

21. Drosophila_sgRNA_group_3

    Pooled Library

    #134584

    Purpose

    Targets all other Drosophila genes not included in Groups 1 and 2

    Depositor

    Norbert Perrimon

    Article

    Viswanatha et al Elife. 2018 Jul 27;7. pii: 36333. doi: 1

    Expression

    Insect

    Species

    Drosophila melanogaster

    Use

    CRISPR

    Available since

    Feb. 25, 2020

    Availability

    Academic Institutions and Nonprofits only

22. Drosophila_sgRNA_group_1

    Pooled Library

    #134582

    Purpose

    Targets kinases, phosphatases, and Drosophila orthologs of drug targets

    Depositor

    Norbert Perrimon

    Article

    Viswanatha et al Elife. 2018 Jul 27;7. pii: 36333. doi: 1

    Expression

    Insect

    Species

    Drosophila melanogaster

    Use

    CRISPR

    Available since

    Feb. 25, 2020

    Availability

    Academic Institutions and Nonprofits only

23. RNA-binding protein pooled CRISPR knockout library

    Pooled Library

    #141438

    Purpose

    CRISPR knockout library targets RBPs with 10 sgRNAs/gene

    Depositor

    Eugene Yeo

    Article

    Wheeler et al Nat Methods. 2020 May 11. pii: 10.1038/s

    Expression

    Mammalian

    Use

    CRISPR and Lentiviral

    Available since

    May 28, 2020

    Availability

    Academic Institutions and Nonprofits only

24. Bassik lab Human CRISPR-Cas9 Deletion Library - Gene Expression

    Pooled Library

    #101928

    Purpose

    Bassik lab Human CRISPR-Cas9 Deletion Library - Gene Expression. Coexpresses mCherry.

    Depositor

    Michael Bassik

    Article

    Morgens et al Nat Commun. 2017 May 5;8:15178. doi: 10.

    Expression

    Mammalian

    Use

    CRISPR

    Available since

    May 23, 2018

    Availability

    Academic Institutions and Nonprofits only

25. Bassik lab Human CRISPR-Cas9 Deletion Library - Membrane proteins

    Pooled Library

    #101929

    Purpose

    Bassik lab Human CRISPR-Cas9 Deletion Library - Membrane proteins. Coexpresses mCherry.

    Depositor

    Michael Bassik

    Article

    Morgens et al Nat Commun. 2017 May 5;8:15178. doi: 10.

    Expression

    Mammalian

    Use

    CRISPR

    Available since

    May 23, 2018

    Availability

    Academic Institutions and Nonprofits only

26. Mouse GeCKO Lentiviral sgRNA Library (LentiCRISPR)

    Pooled Library

    #1000000052

    Purpose

    CRISPR gRNA knockout pooled library for targeting the mouse genome

    Depositor

    Feng Zhang

    Available since

    July 23, 2014

    Availability

    Academic Institutions and Nonprofits only

27. Mouse Brie kinome pooled library, guides 1-4 in lentiCRISPRv2 backbone

    Pooled Library

    #75317

    Purpose

    Mouse sgRNA library in backbone lentiCRISPRv2 targeting 713 kinase genes and containing 2,852 unique sgRNAs along with 100 non-targeting controls

    Depositor

    David Root, John Doench

    Article

    Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

    Available since

    June 27, 2016

    Availability

    Academic Institutions and Nonprofits only

28. Bassik lab Human CRISPR-Cas9 Deletion Library - Proteostasis

    Pooled Library

    #101930

    Purpose

    Bassik lab Human CRISPR-Cas9 Deletion Library - Proteostasis. Coexpresses mCherry.

    Depositor

    Michael Bassik

    Article

    Morgens et al Nat Commun. 2017 May 5;8:15178. doi: 10.

    Expression

    Mammalian

    Use

    CRISPR

    Available since

    May 23, 2018

    Availability

    Academic Institutions and Nonprofits only

29. Human Transporter Knockout library

    Pooled Library

    #213695

    Purpose

    Next generation transporter-focused CRISPR/Cas9 library targeting transmembrane transporters to test the impact of transporters on biological processes.

    Depositor

    RESOLUTE Consortium, Giulio Superti-Furga

    Article

    Ferdigg et al Life Sci Alliance. 2024 Nov 22;8(2):e202

    Species

    Homo sapiens

    Use

    CRISPR and Lentiviral

    Available since

    Sept. 13, 2024

    Availability

    Academic Institutions and Nonprofits only

30. Human Base Editing Sensor Library

    Pooled Library

    #179218

    Purpose

    sgRNAs that target frequently occurring cancer associated mutations identified in the MSK IMPACT dataset that can be modeled with cytosine base editing.

    Depositor

    Lukas Dow

    Article

    Sanchez-Rivera et al Nat Biotechnol. 2022 Feb 14. pii: 10.103

    Expression

    Mammalian

    Use

    Lentiviral

    Available since

    June 16, 2022

    Availability

    Academic Institutions and Nonprofits only