390 results

#101931

Bassik lab Human CRISPR-Cas9 Deletion Library - Trafficking, mitochondrial, motility. Coexpresses mCherry.

Michael Bassik

Morgens et al Nat Commun. 2017 May 5;8:15178. doi: 10.

May 23, 2018

Academic Institutions and Nonprofits only

#90294

Optimized library offering improved accuracy, efficiency, and scalability for CRISPR screens compared to TKOv1

Jason Moffat

Hart et al G3 (Bethesda). 2017 Aug 7;7(8):2719-2727

May 5, 2017

Academic Institutions and Nonprofits only

#247026

Human genome-wide CRISPR knockout library for the use of S. pyogenes Cas9. Each gene is targeted by 3 constructs.

John Doench, David Root

Drepanos et al bioRxiv 2025.08.26.672375; doi: https://

Oct. 2, 2025

Academic Institutions and Nonprofits only

#200011

Knockout library targeting a comprehensive set of mouse genes with annotated function as chromatin regulators.

Bradley Bernstein, Gabriel Griffin, Robert Manguso

Griffin et al Nature. 2021 Jul;595(7866):309-314. doi:

Dec. 15, 2023

Academic Institutions and Nonprofits only

#213694

Inducible barcoded library with 467 codon-optimized cDNAs with UMIs to test the impact of SLC transporters on biological processes.

RESOLUTE Consortium, Giulio Superti-Furga

Wolf et al Cell Chem Biol. 2024 Dec 24:S2451-9456(2

Aug. 30, 2024

Academic Institutions and Nonprofits only

#140961

Knockout library targeting human genes involved in cellular glycosylation.

Sriram Neelamegham

Zhu et al Glycobiology. 2020 Aug 8. pii: 5889976.

Sept. 9, 2020

Academic Institutions and Nonprofits only

#131625

Bacterial inhibition library targeting every small RNA and ORF of the E. coli MG1655 genome. This library has higher inhibition efficiency than the psgRNA library.

David Bikard

Calvo-Villamanan et al Nucleic Acids Res. 2020 Apr 30. pii: 582

May 12, 2020

Academic Institutions and Nonprofits only

#200445

Knockout library targeting mouse cell surface genes.

Junjie Chen

Wang et al Proc Natl Acad Sci U S A. 2022 Jun 21;11

Oct. 26, 2023

Academic Institutions and Nonprofits only

#1000000114

Genome-wide CRISPR gRNA pooled library for inhibition of human genes

John Doench, David Root

July 13, 2018

Academic Institutions and Nonprofits only

#83985

Human CRISPRa Pooled Library targeting membrane proteins

Jonathan Weissman

Horlbeck et al Elife. 2016 Sep 23;5. pii: e19760. doi:

Jan. 12, 2017

Academic Institutions and Nonprofits only

#1000000052

CRISPR gRNA knockout pooled library for targeting the mouse genome

Feng Zhang

July 23, 2014

Academic Institutions and Nonprofits only

#83971

Human CRISPRi Pooled Library tartgeting kinsases, phosphatases and Drug Targets

Jonathan Weissman

Horlbeck et al Elife. 2016 Sep 23;5. pii: e19760. doi:

Dec. 14, 2016

Academic Institutions and Nonprofits only

#207471

CRISPR-based activation library with guide RNAs targeting all cell surface proteins.

Raj Chari

Yang et al Sci Adv. 2024 Feb 16;10(7):eadj2445. doi

Jan. 24, 2024

Academic Institutions and Nonprofits only

#209552

The human, genome-wide, CRISPR knockout enAsCas12a gRNA library targets single genes and paralog pairs, triples, and quads with arrays of 4 gRNAs.

John Doench

Esmaeili Anvar et al Nat Commun. 2024 Apr 27;15(1):3577. doi:

Dec. 5, 2023

Academic Institutions and Nonprofits only

#67988

Knockout library targeting 18,424 mouse genes. gRNAs were improved using a new design pipeline and improved gRNA scaffold.

Kosuke Yusa

Tzelepis et al Cell Rep. 2016 Oct 18;17(4):1193-1205. d

Oct. 14, 2016

Academic Institutions and Nonprofits only

#1000000192

Jonathan Weissman

Sept. 30, 2022

Academic Institutions and Nonprofits only

#179775

SPLINTR (Single-cell Profiling and LINeage TRacing) is a high diversity lentiviral barcode library for tracing clonal lineages using bulk and single-cell readouts.

Mark Dawson

Fennell et al Nature. 2022 Jan;601(7891):125-131. doi:

May 11, 2022

Academic Institutions and Nonprofits only

#1000000083

CRISPR gRNA knockout pooled library for targeting the human kinome

John Doench, David Root

June 27, 2016

Academic Institutions and Nonprofits only

#92379

CRISPRa

John Doench, David Root

Sanson et al Nat Commun. 2018 Dec 21;9(1):5416. doi:

Aug. 3, 2017

Academic Institutions and Nonprofits only

#115643

Viral barcoding library to combinatorially index cells for single-cell analysis of clonal dynamics

Samantha Morris

Biddy et al Nature. 2018 Dec;564(7735):219-224. doi:

Dec. 5, 2018

Academic Institutions and Nonprofits only

#140219

Knockout library targeting human DNA damage response and DNA repair genes.

Junjie Chen

Su et al DNA Repair (Amst). 2020 Jan 16;87:102803

Aug. 20, 2021

Academic Institutions and Nonprofits only

#1000000254

Xue Liu

June 5, 2025

Academic Institutions and Nonprofits only

#67989

Knockout library targeting 18,010 human genes. gRNAs were improved using a new design pipeline and improved gRNA scaffold.

Kosuke Yusa

Tzelepis et al Cell Rep. 2016 Oct 18;17(4):1193-1205. d

Oct. 14, 2016

Academic Institutions and Nonprofits only

#226117

Contains 748 traditional and newly predicted epigenetic regulators using epigenetic network analyses that integrated gene codependency (DepMap) and protein-protein interaction data (BioPlex).

Rui Lu

Zhou et al Blood. 2024 Aug 16:blood.2023023644. doi

Oct. 29, 2024

Academic Institutions and Nonprofits only

#163954

Targets open reading frames and non-coding RNAs in M. tuberculosis.

Jeremy Rock

Bosch et al Cell. 2021 Jul 16. pii: S0092-8674(21)00

Oct. 1, 2021

Academic Institutions and Nonprofits only

#180483

High Complexity Lentiviral Barcode Library

Tomasz Nowakowski

Delgado et al Nature. 2021 Dec 15. pii: 10.1038/s41586

Sept. 12, 2022

Academic Institutions and Nonprofits only

#164896

Genome-wide knockout library designed with two sgRNAs per gene.

Mathew Garnett

Gonçalves et al Genome Biol. 2021 Jan 21;22(1):40. doi:

May 20, 2021

Academic Institutions and Nonprofits only

#160129

Targets mouse metabolic genes and includes most metabolic enzymes and transporters.

Kivanc Birsoy

Zhu et al Cell Metab. 2020 Oct 28. pii: S1550-4131

Nov. 10, 2020

Academic Institutions and Nonprofits only

#136986

Designed for assays with limited cell numbers with 2 guides per gene. Compatible with John Doench’s Brunello human genome-wide library.

John Doench

DeWeirdt et al Nat Commun. 2020 Feb 6;11(1):752. doi: 1

Feb. 24, 2020

Academic Institutions and Nonprofits only

#178943

Barcoding library for the macsGESTALT inducible lineage recording system

Christopher Lengner

Simeonov et al Cancer Cell. 2021 Aug 9;39(8):1150-1162.

March 22, 2022

Academic Institutions and Nonprofits only