We narrowed to 16,253 results for: GRN

1. L2_2xNOP1gRNA-Cas9-CsA

   Plasmid

   #136140

   Purpose

   Plasmid with 2 different NOP1-gRNA. Targets 500 bp apart in the genome. To tranform Mp as CRISPR control. Contains Cas9 and HygR

   Depositor

   Jim Haseloff

   Article

   Sauret-Gueto et al ACS Synth Biol. 2020 Mar 12. doi: 10.102

   Insert

   p5-35S:HygR p5-MpU6:NOP1gRNA2 p5-MpU6:NOP1gRNA1 p5-MpEF1a:Cas9-NLS
   

   Use

   Synthetic Biology

   Expression

   Plant

   Mutation

   BsaI/ SapI domesticated

   Available Since

   Nov. 30, 2021

   Availability

   Academic Institutions and Nonprofits only

   

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2. pX330_ACTB-e1 sgRNA / hSpCas9

   Plasmid

   #172830

   Purpose

   Mammalian expression of a sgRNA targeting the exon 2 position 1 of ACTB (Zhong et al, eLife 2021) under the U6 promotor and hSpCas9 under the CAG promotor. This construct is based on pX330.

   Depositor

   Haining Zhong

   Article

   Zhong et al Elife. 2021 Jun 8;10. pii: 64911. doi: 1

   Insert

   sgRNA targeting the exon 2 of ACTB under the U6 promotor and hSpCas9 under the CAG promotor
   

   Use

   CRISPR

   Expression

   Mammalian

   Available Since

   Aug. 25, 2021

   Availability

   Academic Institutions and Nonprofits only

   

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3. pX330_ACTB-e2 sgRNA / hSpCas9

   Plasmid

   #172831

   Purpose

   Mammalian expression of a sgRNA targeting the exon 2 position 2 of ACTB (Zhong et al, eLife 2021) under the U6 promotor and hSpCas9 under the CAG promotor. This construct is based on pX330.

   Depositor

   Haining Zhong

   Article

   Zhong et al Elife. 2021 Jun 8;10. pii: 64911. doi: 1

   Insert

   sgRNA targeting the exon 2 of ACTB under the U6 promotor and hSpCas9 under the CAG promotor
   

   Use

   CRISPR

   Expression

   Mammalian

   Available Since

   Aug. 25, 2021

   Availability

   Academic Institutions and Nonprofits only

   

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4. pX330_Camk2a sgRNA / hSpCas9

   Plasmid

   #172839

   Purpose

   Mammalian expression of a sgRNA targeting the intron 17 (last intron) of Camk2a (Zhong et al, eLife 2021) under the U6 promotor and hSpCas9 under the CAG promotor. This construct is based on pX330.

   Depositor

   Haining Zhong

   Article

   Zhong et al Elife. 2021 Jun 8;10. pii: 64911. doi: 1

   Insert

   sgRNA targeting intron 17 of Camk2a under the U6 promotor and hSpCas9 under the CAG promotor
   

   Use

   CRISPR

   Expression

   Mammalian

   Available Since

   Aug. 25, 2021

   Availability

   Academic Institutions and Nonprofits only

   

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5. pX330_ACTB-i5 sgRNA / hSpCas9

   Plasmid

   #172829

   Purpose

   Mammalian expression of a sgRNA targeting the intron 1 position 5 of ACTB (Zhong et al, eLife 2021) under the U6 promotor and hSpCas9 under the CAG promotor. This construct is based on pX330.

   Depositor

   Haining Zhong

   Article

   Zhong et al Elife. 2021 Jun 8;10. pii: 64911. doi: 1

   Insert

   sgRNA targeting the intron 1 of ACTB under the U6 promotor and hSpCas9 under the CAG promotor
   

   Use

   CRISPR

   Expression

   Mammalian

   Available Since

   Aug. 24, 2021

   Availability

   Academic Institutions and Nonprofits only

   

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6. pX330_ACTB-i3 sgRNA / hSpCas9

   Plasmid

   #172827

   Purpose

   Mammalian expression of a sgRNA targeting the intron 1 position 3 of ACTB (Zhong et al, eLife 2021) under the U6 promotor and hSpCas9 under the CAG promotor. This construct is based on pX330.

   Depositor

   Haining Zhong

   Article

   Zhong et al Elife. 2021 Jun 8;10. pii: 64911. doi: 1

   Insert

   sgRNA targeting the intron 1 of ACTB under the U6 promotor and hSpCas9 under the CAG promotor
   

   Use

   CRISPR

   Expression

   Mammalian

   Available Since

   Aug. 24, 2021

   Availability

   Academic Institutions and Nonprofits only

   

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7. pX330_ACTB-i2 sgRNA / hSpCas9

   Plasmid

   #172826

   Purpose

   Mammalian expression of a sgRNA targeting the intron 1 position 2 of ACTB (Zhong et al, eLife 2021) under the U6 promotor and hSpCas9 under the CAG promotor. This construct is based on pX330.

   Depositor

   Haining Zhong

   Article

   Zhong et al Elife. 2021 Jun 8;10. pii: 64911. doi: 1

   Insert

   sgRNA targeting the intron 1 of ACTB under the U6 promotor and hSpCas9 under the CAG promotor
   

   Use

   CRISPR

   Expression

   Mammalian

   Available Since

   Aug. 24, 2021

   Availability

   Academic Institutions and Nonprofits only

   

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8. pSico_U6-PLOD2 sgRNA3

   Plasmid

   #136458

   Purpose

   Expression of gRNA against human PLOD2

   Depositor

   Antonio Amelio

   Article

   Sato et al Neoplasia. 2021 Jun 6;23(6):594-606. doi

   Insert

   gRNA against human PLOD2 (PLOD2 Synthetic, Human)
   

   Use

   CRISPR and Lentiviral

   Expression

   Mammalian

   Available Since

   June 7, 2021

   Availability

   Academic Institutions and Nonprofits only

   

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9. pSico_U6-PLOD2 sgRNA5

   Plasmid

   #136460

   Purpose

   Expression of gRNA against human PLOD2

   Depositor

   Antonio Amelio

   Article

   Sato et al Neoplasia. 2021 Jun 6;23(6):594-606. doi

   Insert

   gRNA against human PLOD2 (PLOD2 Synthetic, Human)
   

   Use

   CRISPR and Lentiviral

   Expression

   Mammalian

   Available Since

   June 7, 2021

   Availability

   Academic Institutions and Nonprofits only

   

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10. pVMG0217_Cq-U6-2b_2xBbsI-gRNA

    Plasmid

    #169339

    Purpose

    Expression of gRNA in Culex quinquefasciatus or other mosquitoes

    Depositor

    Valentino Gantz

    Article

    Feng et al Nat Commun. 2021 May 20;12(1):2960. doi:

    Insert

    pVMG0217_Cq-U6-2b_2xBbsI-gRNA
    

    Use

    CRISPR

    Expression

    Insect

    Promoter

    CPIJ039728

    Available Since

    May 21, 2021

    Availability

    Academic Institutions and Nonprofits only

    

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11. pSico_U6-PGC1a1 sgRNA

    Plasmid

    #165425

    Purpose

    Expression of gRNA against human PGC-1a variant 1

    Depositor

    Antonio Amelio

    Article

    Musicant et al Cell Rep. 2021 Feb 23;34(8):108768. doi:

    Insert

    gRNA against PGC-1a variant 1 (PPARGC1A Synthetic, Human)
    

    Use

    CRISPR and Lentiviral

    Expression

    Mammalian

    Available Since

    April 9, 2021

    Availability

    Academic Institutions and Nonprofits only

12. px330 WAPL gRNA

    Plasmid

    #165595

    Purpose

    Insertion of WAPL degrom

    Depositor

    Cornelis Murre

    Article

    Zhu et al Genes Dev. 2021 Jan 1;35(1-2):65-81. doi

    Insert

    WAPL (Wapl Mouse)
    

    Expression

    Mammalian

    Mutation

    NA

    Available Since

    March 12, 2021

    Availability

    Academic Institutions and Nonprofits only

    

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13. px330 BRM gRNA

    Plasmid

    #165586

    Purpose

    Insertion of BRM degron

    Depositor

    Cornelis Murre

    Article

    Zhu et al Genes Dev. 2021 Jan 1;35(1-2):65-81. doi

    Insert

    BRM (Smarca4 Mouse)
    

    Expression

    Mammalian

    Mutation

    NA

    Available Since

    March 11, 2021

    Availability

    Academic Institutions and Nonprofits only

    

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14. pT7gRNA-ttn.1_C3

    Plasmid

    #140866

    Purpose

    sgRNA synthesis vector for ttn.1_C3 (zebrafish titin .1).

    Depositor

    Rob Parton

    Article

    Hall et al Nat Commun. 2020 Jul 24;11(1):3711. doi:

    Insert

    zebrafish ttn.1_C3 sgRNA for in vitro transcription (ttn.1 Synthetic, Zebrafish)
    

    Use

    In vitro transcription of sgrnas

    Available Since

    March 9, 2021

    Availability

    Academic Institutions and Nonprofits only

    

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15. pGL3-U6-sgRNA_FANCF-mcherry

    Plasmid

    #159786

    Purpose

    S. pyogenes sgRNA collocated with pegRNA targeting human FANCF gene

    Depositor

    Xiaolong Wang

    Article

    Liu et al Cell Discov. 2020 Apr 28;6:27. doi: 10.1

    Insert

    spacer of sgRNA targeting FANCF gene (FANCF Human)
    

    Expression

    Mammalian

    Available Since

    Oct. 20, 2020

    Availability

    Academic Institutions and Nonprofits only

    

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16. Lenti-XYLT2-sgRNA

    Plasmid

    #154862

    Purpose

    Lentiviral expression of Cas9 and sgRNA targeting XYLT2

    Depositor

    Yihong Ye

    Article

    Zhang et al Proc Natl Acad Sci U S A. 2020 May 19;11

    Insert

    XYLT2 sgRNA (XYLT2 Human)
    

    Use

    CRISPR and Lentiviral

    Expression

    Mammalian

    Promoter

    U6

    Available Since

    July 27, 2020

    Availability

    Academic Institutions and Nonprofits only

    

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17. Lenti-Myosin7B-sgRNA

    Plasmid

    #154861

    Purpose

    Lentiviral expression of Cas9 and sgRNA targeting Myosin7B

    Depositor

    Yihong Ye

    Article

    Zhang et al Proc Natl Acad Sci U S A. 2020 May 19;11

    Insert

    MYO7B sgRNA (MYO7B Human)
    

    Use

    CRISPR and Lentiviral

    Expression

    Mammalian

    Promoter

    U6

    Available Since

    July 27, 2020

    Availability

    Academic Institutions and Nonprofits only

    

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18. sgRNA BRCA2 S3070F

    Plasmid

    #139325

    Purpose

    Plasmid expressing a sgRNA to introduce BRCA2 S3070F using base editing

    Depositor

    Alberto Ciccia

    Article

    Billon et al Cell Rep. 2020 Mar 10;30(10):3280-3295.e

    Insert

    sgRNA to insert BRCA2 S3070F using base editing
    

    Expression

    Mammalian

    Promoter

    U6

    Available Since

    May 22, 2020

    Availability

    Academic Institutions and Nonprofits only

    

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19. sgRNA BRCA1 S1363L

    Plasmid

    #139329

    Purpose

    Plasmid expressing a sgRNA to introduce BRCA1 S1363L using base editing

    Depositor

    Alberto Ciccia

    Article

    Billon et al Cell Rep. 2020 Mar 10;30(10):3280-3295.e

    Insert

    sgRNA to insert BRCA1 S1363L using base editing
    

    Expression

    Mammalian

    Promoter

    U6

    Available Since

    May 22, 2020

    Availability

    Academic Institutions and Nonprofits only

    

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20. sgRNA BRCA1 E1754K

    Plasmid

    #139330

    Purpose

    Plasmid expressing a sgRNA to introduce BRCA1 E1754K using base editing

    Depositor

    Alberto Ciccia

    Article

    Billon et al Cell Rep. 2020 Mar 10;30(10):3280-3295.e

    Insert

    sgRNA to insert BRCA1 E1754K using base editing
    

    Expression

    Mammalian

    Promoter

    U6

    Available Since

    May 22, 2020

    Availability

    Academic Institutions and Nonprofits only

    

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