4,177 results

1. pBabe-Puro-BRAF-V600E

   Plasmid

   #15269

   Purpose

   Retroviral expression of BRAF V600E (the V600E mutation has been found in cancer patients, confers increased kinase activity, and is transforming)

   Depositor

   William Hahn

   Article

   Boehm et al Cell. 2007 Jun 15. 129(6):1065-1079.

   Insert

   BRAF (BRAF Human)
   

   Use

   Retroviral

   Tags

   His and Myc

   Expression

   Mammalian

   Mutation

   Valine 600 to Glutamate (mutation has been found …

   Available Since

   July 12, 2007

   Availability

   Academic Institutions and Nonprofits only

   

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2. pCSCMV:tdTomato

   Plasmid

   #30530

   Purpose

   mammalian expression of tdTomato controlled by the ubiquitously active CMV promoter.

   Depositor

   Gerhart Ryffel

   Article

   Waldner et al BMC Dev Biol. 2009 Jun 23;9:37. doi: 10.

   Has Service

   Cloning Grade DNA

   Insert

   tdTomato
   

   Expression

   Mammalian

   Mutation

   R415H

   Available Since

   Oct. 6, 2011

   Availability

   Academic Institutions and Nonprofits only

   

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3. pCMVInt

   Plasmid

   #18935

   Depositor

   Michele Calos

   Article

   Groth et al Proc Natl Acad Sci U S A. 2000 May 23. 9

   Insert

   phiC31 integrase (int Streptomyces phage phiC31)
   

   Expression

   Mammalian

   Available Since

   Aug. 13, 2008

   Availability

   Academic Institutions and Nonprofits only

   

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4. GFP-rab9 WT

   Plasmid

   #12663

   Depositor

   Richard Pagano

   Article

   Choudhury et al J Clin Invest. 2002 Jun . 109(12):1541-5

   Insert

   RAB9 (Homo sapiens) (RAB9A Human)
   

   Tags

   GFP and HA

   Expression

   Mammalian

   Available Since

   Oct. 16, 2006

   Availability

   Academic Institutions and Nonprofits only

   

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5. IRE1 alpha-pcDNA3.EGFP

   Plasmid

   #13009

   Depositor

   Fumihiko Urano

   Article

   Lipson et al Cell Metab. 2006 Sep . 4(3):245-54.

   Insert

   Inositol Requiring Enzyme-1 (ERN1 Human)
   

   Expression

   Mammalian

   Available Since

   Nov. 27, 2006

   Availability

   Academic Institutions and Nonprofits only

   

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6. pAAV/D374Y-hPCSK9

   Plasmid

   #58379

   Purpose

   Expresses GoF mutant human PCSK9 to be used for rAAV8-mediated gene transfer, hypercholesterolemia and atherosclerosis

   Depositor

   Jacob Bentzon

   Article

   Bjorklund et al Circ Res. 2014 May 23;114(11):1684-9. do

   Insert

   proprotein convertase subtilisin/kexin type 9 (PCSK9 Human)
   

   Use

   AAV

   Expression

   Mammalian

   Mutation

   D374Y

   Promoter

   HCRApoE/hAAT

   Available Since

   Aug. 26, 2014

   Availability

   Academic Institutions and Nonprofits only

   

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7. pCAG-Kir2.1-T2A-tdTomato

   Plasmid

   #60598

   Purpose

   Expresses Kir2.1-T2A-tdTomato

   Depositor

   Massimo Scanziani

   Article

   Xue et al Nature. 2014 Jul 31;511(7511):596-600. d

   Insert

   Kir2.1-T2A-tdTomato (Kcnj2 Mouse)
   

   Tags

   myc

   Expression

   Mammalian

   Available Since

   Nov. 10, 2014

   Availability

   Academic Institutions and Nonprofits only

   

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8. Klotho (membrane)

   Plasmid

   #17712

   Depositor

   Hal Dietz

   Article

   Arking et al Proc Natl Acad Sci U S A. 2002 Jan 22. 9

   Insert

   Klotho (KL Human)
   

   Tags

   V5

   Expression

   Mammalian

   Mutation

   P101S

   Available Since

   April 14, 2008

   Availability

   Academic Institutions and Nonprofits only

   

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9. pCI-ASC-HA

   Plasmid

   #41553

   Depositor

   Kate Fitzgerald

   Article

   Hornung et al Nature. 2009 Mar 26. 458(7237):514-8.

   Insert

   ASC (PYCARD Human)
   

   Tags

   HA

   Expression

   Mammalian

   Promoter

   CMV immediate-early enhancer/promoter

   Available Since

   Dec. 20, 2012

   Availability

   Academic Institutions and Nonprofits only

   

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10. xCas9(3.7)-ABE(7.10)

    Plasmid

    #108382

    Purpose

    Mammalian expression vector for xCas9(3.7)-ABE

    Depositor

    David Liu

    Article

    Hu et al Nature. 2018 Feb 28. pii: nature26155. d

    Insert

    xCas9(3.7)-ABE(7.10)
    

    Tags

    NLS

    Expression

    Mammalian

    Mutation

    A262T, R324L, S409I, E480K, E543D, M694I, E1219V

    Available Since

    March 28, 2018

    Availability

    Academic Institutions and Nonprofits only

    

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11. HA-AMOT p130

    Plasmid

    #32821

    Depositor

    Kunliang Guan

    Article

    Zhao et al Genes Dev. 2011 Jan 1;25(1):51-63.

    Insert

    AMOT p130 (AMOT Human)
    

    Tags

    2xHA

    Expression

    Mammalian

    Mutation

    E5D

    Promoter

    CMV

    Available Since

    Jan. 11, 2012

    Availability

    Academic Institutions and Nonprofits only

    

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12. pcDNA3-cdk5GFP

    Plasmid

    #1346

    Depositor

    Li-Huei Tsai

    Insert

    CDK5 (CDK5 Human)
    

    Tags

    GFP

    Expression

    Mammalian

    Promoter

    CMV

    Available Since

    April 13, 2006

    Availability

    Academic Institutions and Nonprofits only

    

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13. HA-TAZ-S89A

    Plasmid

    #32840

    Depositor

    Kunliang Guan

    Article

    Lei et al Mol Cell Biol. 2008 Apr;28(7):2426-36. E

    Insert

    TAZ (WWTR1 Human)
    

    Tags

    HA

    Expression

    Mammalian

    Mutation

    S89A

    Promoter

    CMV

    Available Since

    Nov. 15, 2011

    Availability

    Academic Institutions and Nonprofits only

    

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14. EdTP

    Plasmid

    #24311

    Depositor

    Roel Nusse

    Article

    Fuerer et al PLoS One. 2010 . 5(2):e9370.

    Insert

    EF1alpha-dnhTcf4 // SV40-PuroR (TCF7L2 Human)
    

    Use

    Lentiviral

    Tags

    FLAG

    Mutation

    31 first amino acids of hTcf4 have been deleted.

    Available Since

    April 5, 2010

    Availability

    Academic Institutions and Nonprofits only

    

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15. mRFP-Ub

    Plasmid

    #11935

    Depositor

    Nico Dantuma

    Article

    Bergink et al Genes Dev. 2006 May 15. 20(10):1343-52.

    Insert

    Ubiquitin (RBX1 Human)
    

    Tags

    mRFP

    Expression

    Mammalian

    Available Since

    July 5, 2006

    Availability

    Academic Institutions and Nonprofits only

    

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16. pLEX_306

    Plasmid

    #41391

    Purpose

    Constitutive lentiviral expression, SV40-puro; PGK-gateway-V5 tag

    Depositor

    David Root

    Type

    Empty backbone

    Use

    Lentiviral; Gateway destination vector

    Tags

    V5

    Expression

    Mammalian

    Promoter

    PGK

    Available Since

    Nov. 30, 2012

    Availability

    Academic Institutions and Nonprofits only

    

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17. Flag-HA-USP8

    Plasmid

    #22608

    Depositor

    Wade Harper

    Article

    Sowa et al Cell. 2009 Jul 23. 138(2):389-403.

    Insert

    USP8 (USP8 Human)
    

    Use

    Retroviral

    Tags

    FLAG and HA

    Expression

    Mammalian

    Mutation

    None

    Available Since

    Dec. 16, 2009

    Availability

    Academic Institutions and Nonprofits only

    

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18. pCMV14-3X-Flag-SARS-CoV-2 S

    Plasmid

    #145780

    Purpose

    Over expression of SARS-CoV-2 S (spike) in mammalian cell line

    Depositor

    Zhaohui Qian

    Article

    Ou et al Nat Commun. 2020 Mar 27;11(1):1620. doi:

    Insert

    SARS-CoV-2 S (S SARS CoV 2)
    

    Tags

    3xFlag

    Expression

    Mammalian

    Mutation

    Codon optimized and C-terminal 19 amino acids del…

    Promoter

    CMV

    Available Since

    May 6, 2020

    Availability

    Industry, Academic Institutions, and Nonprofits

    

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19. pNANOG-Luc

    Plasmid

    #25900

    Depositor

    Ren-he Xu

    Article

    Xu et al Cell Stem Cell. 2008 Aug 7. 3(2):196-206

    Insert

    NANOG promoter (NANOG Human)
    

    Tags

    Luciferase

    Expression

    Mammalian

    Mutation

    None

    Available Since

    Aug. 5, 2010

    Availability

    Academic Institutions and Nonprofits only

    

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20. pmax pona 12xTRICK 24xMS2SL

    Plasmid

    #64542

    Purpose

    TRICK translation biosensor with 12x copies of modified PP7 stem loops and 24x MS2 stem loops.

    Depositor

    Jeffrey Chao

    Article

    Halstead et al Science. 2015 Mar 20;347(6228):1367-671.

    Insert

    12x PP7 stem-loops
    

    Tags

    24xMS2 stem loops, HA, NLS, and dNP799

    Expression

    Mammalian

    Promoter

    ponA

    Available Since

    May 7, 2015

    Availability

    Academic Institutions and Nonprofits only

    

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