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pIND21-puro_SOX10-OLIG2-3xFLAG

Plasmid

#250321

Purpose

Tetracycline-inducible expression of SOX10-OLIG2 as polyprotein linked by self cleavage sites P2A. rtTA (Tet-ON) is driven the EF1alpha promoter.

Depositor

Michael Wehr

Article

Raabe et al Cells. 2022 Jan 11;11(2):241. doi: 10.33

Insert

SOX10-P2A-OLIG2 (SOX10, OLIG2 Human)

Use

Lentiviral

Tags

3xFLAG

Expression

Mammalian

Promoter

TRE2

Available Since

Feb. 26, 2026

Availability

Academic Institutions and Nonprofits only

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pEGFP-INPP5F-WT

Plasmid

#238070

Purpose

Expression of GFP-INPP5F in mammalian cells

Depositor

Eleanor Coffey

Insert

INPP5F (INPP5F Human)

Tags

GFP

Expression

Mammalian

Promoter

CMV

Available Since

Feb. 18, 2026

Availability

Academic Institutions and Nonprofits only

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pEGFP-INPP5F-Ser940Ala

Plasmid

#238072

Purpose

Expression of GFP-INPP5F in mammalian cells

Depositor

Eleanor Coffey

Insert

INPP5F (INPP5F Human)

Tags

GFP

Expression

Mammalian

Mutation

Serine 940 changed to alanine

Promoter

CMV

Available Since

Feb. 18, 2026

Availability

Academic Institutions and Nonprofits only

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pEGFP-INPP5F-Ser940Asp

Plasmid

#238073

Purpose

Expression of GFP-INPP5F in mammalian cells

Depositor

Eleanor Coffey

Insert

INPP5F (INPP5F Human)

Tags

GFP

Expression

Mammalian

Mutation

Serine 940 changed to aspartate

Promoter

CMV

Available Since

Feb. 18, 2026

Availability

Academic Institutions and Nonprofits only

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pAL10

Plasmid

#236006

Purpose

Backbone for assembling gRNA arrays with LacZ gene for blue white screening

Depositor

Carl de Boer

Article

Salaudeen et al Synth Biol (Oxf). 2025 Dec 18;11(1):ysaf

Type

Empty backbone

Use

CRISPR and Synthetic Biology

Expression

Mammalian

Available Since

Jan. 16, 2026

Availability

Academic Institutions and Nonprofits only

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pCS2+ Flag

Plasmid

#237457

Purpose

Vector for constitutive mammalian expression of gene of interest

Depositor

Thomas Gonatopoulos-Pournatzis

Article

Kumari et al Nat Commun. 2026 Feb 3;17(1):1218. doi:

Type

Empty backbone

Tags

FLAG

Expression

Mammalian

Available Since

Jan. 12, 2026

Availability

Academic Institutions and Nonprofits only

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pIVT-tagBFP_pKG03832

Plasmid

#246370

Purpose

IVT template for making modRNA encoding tagBFP

Depositor

Kate Galloway

Article

Kabaria et al Nat Biotechnol. 2025 Oct 13. doi: 10.103

Insert

tagBFP

Use

Synthetic Biology; In vitro transcription

Expression

Mammalian

Mutation

none

Available Since

Jan. 7, 2026

Availability

Academic Institutions and Nonprofits only

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pAAVLINKv1-pCALM1-Cre-3'-GRIN2A-FLAG

Plasmid

#244301

Purpose

3' AAVLINK plasmid for GRIN2A expression

Depositor

Zhonghua Lu

Article

Lin et al Cell. 2026 Feb 5;189(3):969-986.e17. doi

Insert

GRIN2A (GRIN2A Human)

Use

AAV

Tags

FLAG

Promoter

pCALM1

Available Since

Nov. 4, 2025

Availability

Academic Institutions and Nonprofits only

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pAAVLINK-EF1alpha-5'-GRIN2A

Plasmid

#244300

Purpose

5' AAVLINK plasmid for GRIN2A expression

Depositor

Zhonghua Lu

Article

Lin et al Cell. 2026 Feb 5;189(3):969-986.e17. doi

Insert

GRIN2A (GRIN2A Human)

Use

AAV

Tags

HA

Promoter

EF1alpha

Available Since

Nov. 4, 2025

Availability

Academic Institutions and Nonprofits only

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pAAVLINKv1-pCALM1-Cre-3'-GRIN2B-FLAG

Plasmid

#244255

Purpose

3' AAVLINK plasmid for GRIN2B expression

Depositor

Zhonghua Lu

Article

Lin et al Cell. 2026 Feb 5;189(3):969-986.e17. doi

Insert

GRIN2B (GRIN2B Human)

Use

AAV

Tags

FLAG

Promoter

pCALM1

Available Since

Nov. 3, 2025

Availability

Academic Institutions and Nonprofits only

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pAAVLINK-EF1alpha-5'-GRIN2B

Plasmid

#244254

Purpose

5' AAVLINK plasmid for GRIN2B expression

Depositor

Zhonghua Lu

Article

Lin et al Cell. 2026 Feb 5;189(3):969-986.e17. doi

Insert

GRIN2B (GRIN2B Human)

Use

AAV

Tags

HA

Promoter

EF1alpha

Available Since

Oct. 9, 2025

Availability

Academic Institutions and Nonprofits only

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pET24+ CUL5(1-384)

Plasmid

#246504

Purpose

Recombinant protein expression of CUL5(1-384)

Depositor

Steven Clarke

Article

Pang et al bioRxiv [Preprint]. 2025 May 21:2025.05.

Insert

cullin-5 (CUL5 Human)

Expression

Bacterial

Mutation

Deleted amino acids 385-780

Available Since

Oct. 9, 2025

Availability

Academic Institutions and Nonprofits only

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BsaI-MCS-cloning vector for golden gate

Plasmid

#241214

Depositor

Junsu Kang

Article

Rodriguez-Parks et al Biol Open. 2026 Feb 2:bio.062472. doi: 1

Type

Empty backbone

Use

Minicircle cloning vector

Mutation

TCGC linker

Available Since

Aug. 8, 2025

Availability

Academic Institutions and Nonprofits only

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pJRoC30-LaccID

Plasmid

#234652

Purpose

Expresses LaccID evolved variant in yeast

Depositor

Miguel Alcalde Galeote, Alice Ting

Article

Lee et al Nat Chem Biol. 2025 Aug 1. doi: 10.1038/

Insert

LaccID

Tags

HRV 3C protease site-GSG linker-8xHis tag

Expression

Yeast

Mutation

V11A, Q45R, N74S, R121S, I126V, D255G, L300V

Promoter

Gal1p

Available Since

Aug. 1, 2025

Availability

Academic Institutions and Nonprofits only

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pcDNA3-Lyso-INPP5E

Plasmid

#236004

Purpose

Lysosome-targeted inositol polyphosphate 5 phosphatase (INPP5E); hydrolyzes 5-phosphate in PI(3,4,5)P3 and PI(4,5)P2.

Depositor

Jin Zhang

Article

Sahan et al Proc Natl Acad Sci U S A. 2025 Apr;122(1

Insert

Lyso-INPP5E (LAMP1, INPP5E Synthetic, Human)

Tags

Full-length LAMP1 and mCherry

Expression

Mammalian

Promoter

CMV

Available Since

June 3, 2025

Availability

Academic Institutions and Nonprofits only

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pET29_anti-MERS-Nanobody-VHH-84

Plasmid

#209419

Purpose

Express anti-MERS-Nanobody-VHH-84 in E. coli

Depositor

Magnus Rueping

Article

Peng et al ACS Synth Biol. 2025 Jan 9. doi: 10.1021

Insert

anti-mers-nanobody-vhh-83

Tags

6xHis

Expression

Bacterial

Available Since

Jan. 13, 2025

Availability

Industry, Academic Institutions, and Nonprofits

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3'-com-gRNA GG backbone (MOBE1-4)

Plasmid

#219947

Purpose

Golden gate backbone for mammalian expression of Sp-gRNA with 3'-com

Depositor

Alexis Komor

Article

Cowan et al Nat Biotechnol. 2024 May 21. doi: 10.103

Insert

gRNA-com-3'end (S. pyogenes Cas9)

Use

CRISPR

Expression

Mammalian

Promoter

U6

Available Since

July 30, 2024

Availability

Academic Institutions and Nonprofits only

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pnYC-HsNot1_1-1000_AF

Plasmid

#148739

Purpose

Bacterial Expression of HsNot1_1-1000

Depositor

Elisa Izaurralde

Article

Sgromo et al RNA. 2018 Mar;24(3):381-395. doi: 10.126

Insert

HsNot1_1-1000 (CNOT1 Human)

Expression

Bacterial

Available Since

March 16, 2023

Availability

Academic Institutions and Nonprofits only

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Flag-NLS-MaSat ZF-18-mVenusN

Plasmid

#191392

Purpose

Zinc finger fused to N-terminal part of split mVenus

Depositor

Albert Jeltsch

Article

Lungu et al Nat Commun. 2017 Sep 21;8(1):649. doi: 1

Insert

Flag-NLS-MaSat ZF-18-mVenusN

Tags

3xFLAG

Expression

Mammalian

Promoter

CMV

Available Since

Dec. 19, 2022

Availability

Academic Institutions and Nonprofits only

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PRS_8-somGtACR2-eGFP

Plasmid

#192590

Purpose

AAV-vector for optogenetic silencing of noradrenergic neurons

Depositor

Simon Wiegert

Insert

somGtACR2

Use

AAV

Tags

EGFP - soma-targeting motif from Kv2.1 channel

Expression

Mammalian

Promoter

PRSX8

Available Since

Dec. 8, 2022

Availability

Academic Institutions and Nonprofits only

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