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Showing: 1251 - 1300 of 21042 results

  1. pLenLox_U6 Nlgn1

    Plasmid
    #59339
    Purpose
    Lentiviral expression vector: Neuroligin 1 shRNA under control of mouse U6 promoter, EGFP-expression driven by CAG promoter to monitor expression.
    Depositor
    Peter Scheiffele
    Article
    Chih et al Science. 2005 Feb 25;307(5713):1324-8. E
    Inserts
    Neuroligin 1 shRNA (rat) (Nlgn1 Rat)
    eGFP
    Use
    Lentiviral
    Tags
    Expression
    Mammalian
    Mutation
    Promoter
    CAG and mouse U6
    Available since
    July 21, 2015
    Availability
    Academic Institutions and Nonprofits only
    59339-plasmid-map-sequence-id-92033

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  3. pLentiN 6bE6

    Plasmid
    #37447
    Purpose
    Lentiviral expression of HPV 6bE6 in mammalian cells
    Depositor
    Karl Munger
    Article
    Spangle et al J Virol. 2012 May 2.
    Insert
    HPV 6bE6 (E6 HPV)
    Use
    Lentiviral
    Tags
    Flag and HA
    Expression
    Mammalian
    Mutation
    Promoter
    CMV
    Available since
    Aug. 3, 2012
    Availability
    Academic Institutions and Nonprofits only

  6. pLentiN 18E6no*

    Plasmid
    #37446
    Purpose
    Lentiviral expression of HPV 18E6no* in mammalian cells
    Depositor
    Karl Munger
    Article
    Spangle et al J Virol. 2012 May 2.
    Insert
    HPV 18E6no* (E6 HPV)
    Use
    Lentiviral
    Tags
    Flag and HA
    Expression
    Mammalian
    Mutation
    V44A
    Promoter
    CMV
    Available since
    Aug. 3, 2012
    Availability
    Academic Institutions and Nonprofits only

  7. pLentiN 5E6

    Plasmid
    #37449
    Purpose
    Lentiviral expression of HPV 5E6 in mammalian cells
    Depositor
    Karl Munger
    Article
    Spangle et al J Virol. 2012 May 2.
    Insert
    HPV 5E6 (E6 HPV)
    Use
    Lentiviral
    Tags
    Flag and HA
    Expression
    Mammalian
    Mutation
    Promoter
    CMV
    Available since
    Aug. 23, 2012
    Availability
    Academic Institutions and Nonprofits only

  9. pLEX_307-SARS-CoV-2-NSP3-V5

    Plasmid
    #214429
    Purpose
    Lentiviral-mediated stable expression of SARS-CoV-2 NSP3 in mammalian cells
    Depositor
    Mohan Babu
    Insert
    SARS-CoV-2 NSP3 (part of SARS-CoV-2 ORF1ab) (ORF1ab )
    Use
    Lentiviral
    Tags
    V5 tag
    Expression
    Mammalian
    Mutation
    Promoter
    Available since
    April 30, 2025
    Availability
    Academic Institutions and Nonprofits only
    214429-plasmid-map-sequence-id-437257

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  10. pLD-puro-Cc-IFIT5_K197R-VA

    Plasmid
    #191223
    Purpose
    Lentiviral expression of human IFIT5_K197R in mammalian cells
    Depositor
    Mohan Babu
    Insert
    interferon-induced protein with tetratricopeptide repeats 5 (IFIT5 Human)
    Use
    Lentiviral
    Tags
    VA tag
    Expression
    Mammalian
    Mutation
    changed Lysine 197 to Arginine (K197R)
    Promoter
    CMV
    Available since
    April 30, 2025
    Availability
    Academic Institutions and Nonprofits only
    191223-plasmid-map-sequence-id-467902

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  11. pLD-puro-Cc-SARS-CoV-2_Spike_Beta-VA

    Plasmid
    #191218
    Purpose
    Lentiviral expression of SARS-CoV-2 Spike_Beta in mammalian cells
    Depositor
    Mohan Babu
    Insert
    SPIKE_SARS2_Beta (S SARS CoV-2)
    Use
    Lentiviral
    Tags
    VA tag
    Expression
    Mammalian
    Mutation
    D80A D215G (Del 241-243) K417N E484K N501Y D614G …
    Promoter
    CMV
    Available since
    April 30, 2025
    Availability
    Academic Institutions and Nonprofits only
    191218-plasmid-map-sequence-id-422111

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  12. pLD-puro-Cc-SARS-CoV-2_Spike_Delta-VA

    Plasmid
    #191219
    Purpose
    Lentiviral expression of SARS-CoV-2 Spike_Delta in mammalian cells
    Depositor
    Mohan Babu
    Insert
    SPIKE_SARS2_Delta (S SARS CoV-2)
    Use
    Lentiviral
    Tags
    VA tag
    Expression
    Mammalian
    Mutation
    T19R 156del 157del R158G L452R T478K D614G P681R …
    Promoter
    CMV
    Available since
    April 30, 2025
    Availability
    Academic Institutions and Nonprofits only
    191219-plasmid-map-sequence-id-422106

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  13. pLD-puro-Cc-SARS-CoV-2_Spike_Lambda-VA

    Plasmid
    #191220
    Purpose
    Lentiviral expression of SARS-CoV-2 Spike_Lambda in mammalian cells
    Depositor
    Mohan Babu
    Insert
    SPIKE_SARS2_Lambda (S SARS CoV-2)
    Use
    Lentiviral
    Tags
    VA tag
    Expression
    Mammalian
    Mutation
    G75V T76I Del 246-252 L452Q F490S D614G T859N
    Promoter
    CMV
    Available since
    April 30, 2025
    Availability
    Academic Institutions and Nonprofits only
    191220-plasmid-map-sequence-id-431854

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  14. pLD-puro-Cc-IFIT5_K160R-VA

    Plasmid
    #191222
    Purpose
    Lentiviral expression of human IFIT5_K160R in mammalian cells
    Depositor
    Mohan Babu
    Insert
    interferon-induced protein with tetratricopeptide repeats 5 (IFIT5 Human)
    Use
    Lentiviral
    Tags
    VA tag
    Expression
    Mammalian
    Mutation
    changed Lysine 160 to Arginine (K160R)
    Promoter
    CMV
    Available since
    April 30, 2025
    Availability
    Academic Institutions and Nonprofits only
    191222-plasmid-map-sequence-id-467897

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  15. pLenti Puro HA-Ubiquitin-KO

    Plasmid
    #236292
    Purpose
    Lentiviral vector expressing HA-tagged ubiquitin KO mutant
    Depositor
    Melina Fan, Addgene Research Program
    Insert
    Ubiquitin KO (UBB Human)
    Use
    Lentiviral
    Tags
    HA
    Expression
    Mutation
    Single ubiquitin coding sequence containing KO mu…
    Promoter
    CMV
    Available since
    April 15, 2025
    Availability
    Industry, Academic Institutions, and Nonprofits
    236292-plasmid-map-sequence-id-468935

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  16. pLenti Puro HA-Ubiquitin-K48

    Plasmid
    #236290
    Purpose
    Lentiviral vector expressing HA-tagged ubiquitin K48 mutant
    Depositor
    Melina Fan, Addgene Research Program
    Insert
    Ubiquitin K48 (UBB Human)
    Use
    Lentiviral
    Tags
    HA
    Expression
    Mutation
    Single ubiquitin coding sequence containing K48 m…
    Promoter
    CMV
    Available since
    April 10, 2025
    Availability
    Industry, Academic Institutions, and Nonprofits
    236290-plasmid-map-sequence-id-467837

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  17. pLenti Puro HA-Ubiquitin-K63

    Plasmid
    #236291
    Purpose
    Lentiviral vector expressing HA-tagged ubiquitin K63 mutant
    Depositor
    Melina Fan, Addgene Research Program
    Insert
    Ubiquitin K63 (UBB Human)
    Use
    Lentiviral
    Tags
    HA
    Expression
    Mutation
    Single ubiquitin coding sequence containing K63 m…
    Promoter
    CMV
    Available since
    April 10, 2025
    Availability
    Industry, Academic Institutions, and Nonprofits
    236291-plasmid-map-sequence-id-467835

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  18. pLV-SFFV-ZFYVE27-WPRE-UbC-Emerald

    Plasmid
    #214469
    Purpose
    Lentiviral vector plasmid expressing human zinc finger FYVE-type containing 27 (ZFYVE27) under the spleen focus-forming virus (SFFV) promoter and Emerald under the Ubiquitin C (UbC) promoter
    Depositor
    Bart Nieuwenhuis, Richard Eva
    Inserts
    ZFYVE27 (ZFYVE27 Human)
    Emerald
    Use
    Lentiviral
    Tags
    Expression
    Mammalian
    Mutation
    Promoter
    Available since
    July 11, 2024
    Availability
    Academic Institutions and Nonprofits only
    214469-plasmid-map-sequence-id-425107

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  26. pLTR-SFFV-PTPN2 transcript variant 2-WPRE-UbC-Emerald

    Plasmid
    #201187
    Purpose
    Lentiviral vector plasmid expressing human PTPN2 transcript variant 2 under the spleen focus-forming virus (SFFV) promoter and Emerald under the Ubiquitin C (UbC) promoter
    Depositor
    Bart Nieuwenhuis
    Inserts
    PTPN2, transcript variant 2 (PTPN2 Human)
    Emerald
    Use
    Lentiviral
    Tags
    Expression
    Mammalian
    Mutation
    Promoter
    Available since
    June 23, 2023
    Availability
    Academic Institutions and Nonprofits only
    201187-plasmid-map-sequence-id-398106

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  27. pLTR-SFFV-PTPN2 transcript variant 3-WPRE-UbC-Emerald

    Plasmid
    #201188
    Purpose
    Lentiviral vector plasmid expressing human PTPN2 transcript variant 3 under the spleen focus-forming virus (SFFV) promoter and Emerald under the Ubiquitin C (UbC) promoter
    Depositor
    Bart Nieuwenhuis
    Inserts
    PTPN2, transcript variant 3 (PTPN2 Human)
    Emerald
    Use
    Lentiviral
    Tags
    Expression
    Mammalian
    Mutation
    Promoter
    Available since
    June 23, 2023
    Availability
    Academic Institutions and Nonprofits only
    201188-plasmid-map-sequence-id-398098

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  36. pLX_EFS-Cre_ppt-del

    Plasmid
    #162073
    Purpose
    Compact Cre expression vector with modified PPT designed to generate high-titer non-integrating lentivirus when packaged with PsPax2-D64V (Addgene #63586)
    Depositor
    Robert Manguso
    Article
    Dubrot et al Immunity. 2021 Jan 20. pii: S1074-7613(2
    Insert
    Cre
    Use
    Cre/Lox and Lentiviral
    Tags
    Expression
    Mammalian
    Mutation
    codon-optimized for expression in M. musculus
    Promoter
    EFS (part of insert)
    Available since
    Feb. 22, 2021
    Availability
    Academic Institutions and Nonprofits only
    162073-plasmid-map-sequence-id-325292

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  38. pLenti-nSpCas9-APOBEC3A

    Plasmid
    #209040
    Purpose
    Lentiviral vector expressing doxycycline-inducible human codon-optimized cytosine base editor where APOBEC3A is fused to the N-terminus of SpCas9(D10A)-sDNA Rad51-2xUGI-6xNLS
    Depositor
    Thomas Gonatopoulos-Pournatzis
    Article
    Xiao et al Mol Cell. 2024 Jul 11;84(13):2553-2572.e
    Insert
    APOBEC3A-nSpCas9
    Use
    CRISPR and Lentiviral
    Tags
    FLAG-HA
    Expression
    Mammalian
    Mutation
    D10A
    Promoter
    Tight TRE promoter
    Available since
    June 20, 2024
    Availability
    Academic Institutions and Nonprofits only
    209040-plasmid-map-sequence-id-413592

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  41. Cilantro 2

    Plasmid
    #74450
    Purpose
    Can clone in a C2H2 zinc finger via BsmBI restriction sites and monitor post-translational degradation using EGFP:mCherry ratio (Lentiviral, PGK.BsmBICloneSite-EGFP.IRES.mCherry.cppt.EF1a.PuroR)
    Depositor
    Benjamin Ebert
    Article
    Slabicki et al Nature. 2020 Sep;585(7824):293-297. doi:
    Type
    Empty backbone
    Use
    Lentiviral
    Tags
    EGFP
    Expression
    Mutation
    Promoter
    Available since
    July 5, 2018
    Availability
    Academic Institutions and Nonprofits only
    74450-plasmid-map-sequence-id-140420

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  46. pLenti-nSpCas9-TadA8e

    Plasmid
    #209044
    Purpose
    Lentiviral vector expressing doxycycline-inducible human codon-optimized adenine base editor where TadA8e (ABE8e) is fused to the N-terminus of SpCas9(D10A)-6xNLS
    Depositor
    Thomas Gonatopoulos-Pournatzis
    Article
    Xiao et al Mol Cell. 2024 Jul 11;84(13):2553-2572.e
    Insert
    TadA8e-nSpCas9
    Use
    CRISPR and Lentiviral
    Tags
    FLAG-HA
    Expression
    Mammalian
    Mutation
    D10A
    Promoter
    Tight TRE promoter
    Available since
    June 20, 2024
    Availability
    Academic Institutions and Nonprofits only
    209044-plasmid-map-sequence-id-413636

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  48. EF1a-HexaPro_Foldon-PDGFR-T2A-mCherry (pZYW079)

    Plasmid
    #194234
    Purpose
    Lentiviral expression vector expressing Jason McClellan lab's 6-proline Spike extracellular domain on the cell surface attached to PDGFR's transmembrane domain and mCherry transduction marker
    Depositor
    Hana El-Samad
    Article
    Weinberg et al bioRxiv 2021.04.20.440678
    Insert
    EF1a-Spike ECD-PDGFR TMD-T2A-mCherry (S Synthetic)
    Use
    Lentiviral
    Tags
    Expression
    Mutation
    Promoter
    EF1a
    Available since
    Sept. 10, 2024
    Availability
    Academic Institutions and Nonprofits only
    194234-plasmid-map-sequence-id-383907

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  49. pLenti-nSpCas9-NoCBE

    Plasmid
    #209038
    Purpose
    Lentiviral vector expressing doxycycline-inducible human codon-optimized SpCas9(D10A)-6xNLS (Cas9 nickase) linked to ssDNA binding domain from RAD51 and uracil DNA glycosylase inhibitor (UGI)
    Depositor
    Thomas Gonatopoulos-Pournatzis
    Article
    Xiao et al Mol Cell. 2024 Jul 11;84(13):2553-2572.e
    Insert
    nSpCas9
    Use
    CRISPR and Lentiviral
    Tags
    FLAG-HA
    Expression
    Mammalian
    Mutation
    D10A
    Promoter
    Tight TRE promoter
    Available since
    June 20, 2024
    Availability
    Academic Institutions and Nonprofits only
    209038-plasmid-map-sequence-id-413620

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  50. pLenti-nSpCas9-APOBEC1

    Plasmid
    #209039
    Purpose
    Lentiviral vector expressing doxycycline-inducible human codon-optimized cytosine base editor where APOBEC1 is fused to the N-terminus of SpCas9(D10A)-sDNA Rad51-2xUGI-6xNLS
    Depositor
    Thomas Gonatopoulos-Pournatzis
    Article
    Xiao et al Mol Cell. 2024 Jul 11;84(13):2553-2572.e
    Insert
    APOBEC1-nSpCas9
    Use
    CRISPR and Lentiviral
    Tags
    FLAG-HA
    Expression
    Mammalian
    Mutation
    D10A
    Promoter
    Tight TRE promoter
    Available since
    June 20, 2024
    Availability
    Academic Institutions and Nonprofits only
    209039-plasmid-map-sequence-id-413619

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Showing: 1251 - 1300 of 21042 results