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Plasmid#234761PurposeExpression of the R487L mutant variant of human PDGFRA, which might be associated with Gastrointestinal Stromal TumorDepositorInsertPDGFRA-R487L receptor tyrosine kinase, full length (PDGFRA Human)
UseTagsV5/HisExpressionMammalianMutationR487L substitutionPromoterCMVAvailable sinceApril 15, 2025AvailabilityAcademic Institutions and Nonprofits only -
pcDNA3.1-PDGFRA-D842V-V5/HIS
Plasmid#234763PurposeExpression of the D842V mutant variant of human PDGFRA, which is associated with Gastrointestinal Stromal Tumor, constantly activatedDepositorInsertPDGFRA-D842V receptor tyrosine kinase, full length (PDGFRA Human)
UseTagsV5/HisExpressionMammalianMutationD842V substitutionPromoterCMVAvailable sinceApril 15, 2025AvailabilityAcademic Institutions and Nonprofits only -
pcDNA3.1-PDGFRA-G853D-V5/HIS
Plasmid#234757PurposeExpression of the G853D mutant variant of human PDGFRA, which might be associated with MelanomaDepositorInsertPDGFRA-G853D receptor tyrosine kinase, full length (PDGFRA Human)
UseTagsV5/HisExpressionMammalianMutationG853D substitutionPromoterCMVAvailable sinceApril 15, 2025AvailabilityAcademic Institutions and Nonprofits only -
pcDNA3.1-PDGFRA-T674I-V5/HIS
Plasmid#234756PurposeExpression of the T674I mutant variant of human PDGFRA, which is associated with Idiopathic Hypereosinophilic Syndrome, resistant to imatinibDepositorInsertPDGFRA-T674I receptor tyrosine kinase, full length (PDGFRA Human)
UseTagsV5/HisExpressionMammalianMutationT674I substitutionPromoterCMVAvailable sinceApril 14, 2025AvailabilityAcademic Institutions and Nonprofits only -
pcDNA3.1-PDGFRA-K627M-V5/HIS
Plasmid#234755PurposeExpression of the K627M kinase defective mutant variant of human PDGFRADepositorInsertPDGFRA-K627M receptor tyrosine kinase, full length (PDGFRA Human)
UseTagsV5/HisExpressionMammalianMutationK627M substitutionPromoterCMVAvailable sinceMarch 25, 2025AvailabilityAcademic Institutions and Nonprofits only -
CamKII-LGI1-Y433A-pHluorin
Plasmid#185541PurposeExpresses mutant Y433A LGI1-pHluorin under the CamKII promoterDepositorInsertLGI1 (Lgi1 Rat)
UseLentiviralTagspHluorinExpressionMammalianMutationchanged tyrosine 433 for alaninePromoterCamKIIAvailable sinceMay 3, 2024AvailabilityAcademic Institutions and Nonprofits only -
DDR2 gRNA (BRDN0001147364)
Plasmid#77972Purpose3rd generation lentiviral gRNA plasmid targeting human DDR2DepositorInsertDDR2 (DDR2 Human)
UseCRISPR and LentiviralTagsExpressionMammalianMutationPromoterhU6Available sinceJuly 6, 2016AvailabilityAcademic Institutions and Nonprofits only -
DDR2 gRNA (BRDN0001147484)
Plasmid#77973Purpose3rd generation lentiviral gRNA plasmid targeting human DDR2DepositorInsertDDR2 (DDR2 Human)
UseCRISPR and LentiviralTagsExpressionMammalianMutationPromoterhU6Available sinceJuly 6, 2016AvailabilityAcademic Institutions and Nonprofits only -
DDR2 gRNA (BRDN0001147906)
Plasmid#77974Purpose3rd generation lentiviral gRNA plasmid targeting human DDR2DepositorInsertDDR2 (DDR2 Human)
UseCRISPR and LentiviralTagsExpressionMammalianMutationPromoterhU6Available sinceJuly 6, 2016AvailabilityAcademic Institutions and Nonprofits only -
DDR2 gRNA (BRDN0001487155)
Plasmid#77975Purpose3rd generation lentiviral gRNA plasmid targeting human DDR2DepositorInsertDDR2 (DDR2 Human)
UseCRISPR and LentiviralTagsExpressionMammalianMutationPromoterhU6Available sinceJuly 6, 2016AvailabilityAcademic Institutions and Nonprofits only -
EPHA3 gRNA (BRDN0001148513)
Plasmid#76744Purpose3rd generation lentiviral gRNA plasmid targeting human EPHA3DepositorInsertEPHA3 (EPHA3 Human)
UseCRISPR and LentiviralTagsExpressionMammalianMutationPromoterhU6Available sinceJuly 6, 2016AvailabilityAcademic Institutions and Nonprofits only -
EPHA3 gRNA (BRDN0001145213)
Plasmid#76742Purpose3rd generation lentiviral gRNA plasmid targeting human EPHA3DepositorInsertEPHA3 (EPHA3 Human)
UseCRISPR and LentiviralTagsExpressionMammalianMutationPromoterhU6Available sinceJuly 6, 2016AvailabilityAcademic Institutions and Nonprofits only -
EPHA5 gRNA (BRDN0001146414)
Plasmid#76676Purpose3rd generation lentiviral gRNA plasmid targeting human EPHA5DepositorInsertEPHA5 (EPHA5 Human)
UseCRISPR and LentiviralTagsExpressionMammalianMutationPromoterhU6Available sinceJuly 6, 2016AvailabilityAcademic Institutions and Nonprofits only -
EPHA5 gRNA (BRDN0001149265)
Plasmid#76677Purpose3rd generation lentiviral gRNA plasmid targeting human EPHA5DepositorInsertEPHA5 (EPHA5 Human)
UseCRISPR and LentiviralTagsExpressionMammalianMutationPromoterhU6Available sinceJuly 6, 2016AvailabilityAcademic Institutions and Nonprofits only -
EPHA5 gRNA (BRDN0001149079)
Plasmid#76678Purpose3rd generation lentiviral gRNA plasmid targeting human EPHA5DepositorInsertEPHA5 (EPHA5 Human)
UseCRISPR and LentiviralTagsExpressionMammalianMutationPromoterhU6Available sinceJuly 6, 2016AvailabilityAcademic Institutions and Nonprofits only -
EPHA4 gRNA (BRDN0001145556)
Plasmid#76665Purpose3rd generation lentiviral gRNA plasmid targeting human EPHA4DepositorInsertEPHA4 (EPHA4 Human)
UseCRISPR and LentiviralTagsExpressionMammalianMutationPromoterhU6Available sinceJuly 6, 2016AvailabilityAcademic Institutions and Nonprofits only -
EPHB3 gRNA (BRDN0001147101)
Plasmid#75947Purpose3rd generation lentiviral gRNA plasmid targeting human EPHB3DepositorInsertEPHB3 (EPHB3 Human)
UseCRISPR and LentiviralTagsExpressionMammalianMutationPromoterhU6Available sinceJuly 6, 2016AvailabilityAcademic Institutions and Nonprofits only -
EPHB3 gRNA (BRDN0001146280)
Plasmid#75945Purpose3rd generation lentiviral gRNA plasmid targeting human EPHB3DepositorInsertEPHB3 (EPHB3 Human)
UseCRISPR and LentiviralTagsExpressionMammalianMutationPromoterhU6Available sinceJuly 6, 2016AvailabilityAcademic Institutions and Nonprofits only -
EPHB3 gRNA (BRDN0001145322)
Plasmid#75946Purpose3rd generation lentiviral gRNA plasmid targeting human EPHB3DepositorInsertEPHB3 (EPHB3 Human)
UseCRISPR and LentiviralTagsExpressionMammalianMutationPromoterhU6Available sinceJuly 6, 2016AvailabilityAcademic Institutions and Nonprofits only -
pD649-HAsp-AXL-Fc(DAPA)-AviTag-6xHis
Plasmid#156855PurposeMammalian expression of cell-surface protein extracellular domain fused to Fc(DAPA)-Avi-6xHis. Protein is secreted from cells.DepositorInsertAXL (AXL Human)
UseTagsFc(DAPA)-AviTag-6xHisExpressionMammalianMutationFc region of human IgG contains D265A and P329A m…PromoterCMV/SP6Available sinceMarch 8, 2023AvailabilityAcademic Institutions and Nonprofits only -
pDONR223-TYK2
Plasmid#23908DepositorInsertTYK2 (TYK2 Human)
UseGateway donor vectorTagsExpressionMutationPromoterAvailable sinceJuly 30, 2010AvailabilityAcademic Institutions and Nonprofits only -
pWZL Neo Myr Flag TYK2
Plasmid#20660DepositorInsertTYK2 (TYK2 Human)
UseRetroviralTagsFlag and MyrExpressionMammalianMutationPromoterAvailable sinceOct. 27, 2009AvailabilityAcademic Institutions and Nonprofits only -
pAAV uN2C GFP (Ctl)
Plasmid#224355PurposeExpress GFP tagged upsteram ORF of NOTCH2NLC with a control size (12x) of GGC repeatsDepositorInsertuN2C
UseAAVTagseGFPExpressionMammalianMutationCodon-optimized for expression in human, so no pu…PromoterCMV + chimeric intyron (CAG)Available sinceOct. 7, 2024AvailabilityIndustry, Academic Institutions, and Nonprofits -
pDONR223-SYK
Plasmid#23907DepositorInsertSYK (SYK Human)
UseGateway donor vectorTagsExpressionMutationPromoterAvailable sinceJuly 30, 2010AvailabilityAcademic Institutions and Nonprofits only -
pDONR223-NTRK2
Plasmid#23883DepositorInsertNTRK2 (NTRK2 Human)
UseGateway donor vectorTagsExpressionMutationPromoterAvailable sinceJuly 30, 2010AvailabilityAcademic Institutions and Nonprofits only -
pWZL Neo Myr Flag SYK
Plasmid#20646DepositorInsertSYK (SYK Human)
UseRetroviralTagsFlag and MyrExpressionMammalianMutationPromoterAvailable sinceOct. 27, 2009AvailabilityAcademic Institutions and Nonprofits only -
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pN1 Lck-GCaMP5G
Plasmid#34924PurposeExpresses a fusion between the Lck domain and cytosolic GCaMP5G. This construct targets GCaMP5G to the plasma membraneDepositorInsertLck-GCaMP5G
UseTagsExpressionMammalianMutationPlasmid contains N-terminal 26 amino acid membran…PromoterCMVAvailable sinceFeb. 21, 2012AvailabilityAcademic Institutions and Nonprofits only -
pDONR223-PTK7
Plasmid#23943DepositorInsertPTK7 (PTK7 Human)
UseGateway donor vectorTagsExpressionMutationPromoterAvailable sinceJuly 30, 2010AvailabilityAcademic Institutions and Nonprofits only -
pHAGE-DDR2
Plasmid#116729PurposeLentiviral expression of DDR2DepositorInsertDDR2 (DDR2 Human)
UseLentiviralTagsExpressionMutationWTPromoterAvailable sinceMarch 14, 2019AvailabilityAcademic Institutions and Nonprofits only -
pDONR223-TNK1
Plasmid#23894DepositorInsertTNK1 (TNK1 Human)
UseGateway donor vectorTagsExpressionMutationPromoterAvailable sinceJuly 30, 2010AvailabilityAcademic Institutions and Nonprofits only -
pDONR223-NTRK1
Plasmid#23891DepositorInsertNTRK1 (NTRK1 Human)
UseGateway donor vectorTagsExpressionMutationV263L relative to NM_001012331PromoterAvailable sinceJuly 30, 2010AvailabilityAcademic Institutions and Nonprofits only -
pDONR223-NTRK3
Plasmid#23901DepositorInsertNTRK3 (NTRK3 Human)
UseGateway donor vectorTagsExpressionMutationF441L and L653P relative to NM_001012338.3PromoterAvailable sinceJuly 30, 2010AvailabilityAcademic Institutions and Nonprofits only -
pDONR223-ROR2
Plasmid#23927DepositorInsertROR2 (ROR2 Human)
UseGateway donor vectorTagsExpressionMutationPromoterAvailable sinceJuly 30, 2010AvailabilityAcademic Institutions and Nonprofits only -
pWZL Neo Myr Flag PTK2
Plasmid#20610DepositorInsertPTK2 (PTK2 Human)
UseRetroviralTagsFlag and MyrExpressionMammalianMutationPromoterAvailable sinceOct. 27, 2009AvailabilityAcademic Institutions and Nonprofits only -
pDONR223-PTK2
Plasmid#23902DepositorInsertPTK2 (PTK2 Human)
UseGateway donor vectorTagsExpressionMutationPromoterAvailable sinceJuly 30, 2010AvailabilityAcademic Institutions and Nonprofits only -
pDONR223-PTK6
Plasmid#23899DepositorInsertPTK6 (PTK6 Human)
UseGateway donor vectorTagsExpressionMutationPromoterAvailable sinceJuly 30, 2010AvailabilityAcademic Institutions and Nonprofits only -
pDONR223-PTK2B
Plasmid#23898DepositorInsertPTK2B (PTK2B Human)
UseGateway donor vectorTagsExpressionMutationK42MPromoterAvailable sinceJuly 30, 2010AvailabilityAcademic Institutions and Nonprofits only -
pWZL Neo Myr Flag TNK2
Plasmid#20654DepositorInsertTNK2 (TNK2 Human)
UseRetroviralTagsFlag and MyrExpressionMammalianMutationPromoterAvailable sinceOct. 27, 2009AvailabilityAcademic Institutions and Nonprofits only -
pLX307/PTPN11
Plasmid#140941Purposeexpresses PTPN11DepositorInsertPTPN11 protein tyrosine phosphatase non-receptor type 11 [ Homo sapiens (human) ] (PTPN11 Human)
UseTagsExpressionMammalianMutationPromoterEF1aAvailable sinceJune 4, 2020AvailabilityAcademic Institutions and Nonprofits only