168,503 results

1. pAPM-miR30-XPO1-ts1

   Plasmid

   #174286

   Purpose

   XPO1 knockdown

   Depositor

   Jeremy Luban

   Article

   Guney et al Proc Natl Acad Sci U S A. 2024 Jul 16;12

   Insert

   XPO1 shRNA (XPO1 Human)
   

   Use

   Lentiviral and RNAi

   Promoter

   SFFV

   Available Since

   Aug. 27, 2024

   Availability

   Academic Institutions and Nonprofits only

   

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2. pAPM-miR30-XPO1-ts2

   Plasmid

   #174287

   Purpose

   XPO1 knockdown

   Depositor

   Jeremy Luban

   Article

   Guney et al Proc Natl Acad Sci U S A. 2024 Jul 16;12

   Insert

   XPO1 shRNA (XPO1 Human)
   

   Use

   Lentiviral and RNAi

   Promoter

   SFFV

   Available Since

   Aug. 27, 2024

   Availability

   Academic Institutions and Nonprofits only

   

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3. Halotag-6xHp

   Plasmid

   #214414

   Purpose

   Lipid droplet localization of 6xHp of Spastin fused to Halotag

   Depositor

   Chi-Lun Chang

   Article

   Li et al J Cell Biol. 2024 Sep 2;223(9):e20231112

   Insert

   6x Spastin aa 43-92 (SPAST Human)
   

   Tags

   Halo

   Expression

   Mammalian

   Promoter

   CMV

   Available Since

   March 18, 2024

   Availability

   Academic Institutions and Nonprofits only

   

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4. TFORF1875

   Plasmid

   #142880

   Purpose

   Lentiviral vector for overexpressing transcription factor ORFs with unique 24-bp barcodes. Barcodes facilitate identification of transcription factors in pooled screens.

   Depositor

   Feng Zhang

   Article

   Joung et al Cell. 2023 Jan 5;186(1):209-229.e26. doi

   Insert

   CCNT1 (CCNT1 Human)
   

   Use

   Lentiviral

   Expression

   Mammalian

   Promoter

   EF1a

   Available Since

   June 8, 2023

   Availability

   Academic Institutions and Nonprofits only

   

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5. pFastBac HTB MBP-SARM1

   Plasmid

   #195763

   Purpose

   Purification of SARM1 from insect cells

   Depositor

   Hao Wu

   Insert

   SARM1 (SARM1 Human)
   

   Tags

   HIS-MBP-TEV

   Expression

   Insect

   Promoter

   polyhedrin

   Available Since

   Feb. 16, 2023

   Availability

   Academic Institutions and Nonprofits only

   

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6. Anti-IP3 receptor, type 1 [L24/19R]

   Plasmid

   #188171

   Purpose

   Mammalian Expression Plasmid of anti-IP3 receptor, type 1 (Rat). Derived from hybridoma L24/19

   Depositor

   James Trimmer

   Article

   Mitchell et al Sci Rep. 2023 Sep 27;13(1):16200. doi: 1

   Insert

   anti-IP3 receptor, type 1 (Rattus norvegicus) recombinant mouse monoclonal antibody (Itpr1 Mouse)
   

   Expression

   Mammalian

   Promoter

   Dual CMV

   Available Since

   Nov. 1, 2022

   Availability

   Academic Institutions and Nonprofits only

   

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7. Anti-IP3 receptor, type 1 [L24/21R]

   Plasmid

   #188167

   Purpose

   Mammalian Expression Plasmid of anti-IP3 receptor, type 1 (Rat). Derived from hybridoma L24/21

   Depositor

   James Trimmer

   Article

   Mitchell et al Sci Rep. 2023 Sep 27;13(1):16200. doi: 1

   Insert

   anti-IP3 receptor, type 1 (Rattus norvegicus) recombinant mouse monoclonal antibody (Itpr1 Mouse)
   

   Expression

   Mammalian

   Promoter

   Dual CMV

   Available Since

   Nov. 1, 2022

   Availability

   Academic Institutions and Nonprofits only

   

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8. pLNHA-C1-HsNot8-D40AE42A_U

   Plasmid

   #147647

   Purpose

   Mammalian Expression of HsNot8-D40AE42A

   Depositor

   Elisa Izaurralde

   Article

   Loh et al Genes Dev. 2013 Oct 1;27(19):2125-38. do

   Insert

   HsNot8-D40AE42A (CNOT8 Human)
   

   Expression

   Mammalian

   Available Since

   April 22, 2022

   Availability

   Academic Institutions and Nonprofits only

   

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9. pJEP200-Lenti-TRE3G-Flag-GluN2A-WPRE-pA

   Plasmid

   #164724

   Purpose

   pLenti vector backbone designed to express Flag-GluN2A from a TRE3G promoter.

   Depositor

   Jonathan Ploski

   Article

   Holehonnur et al Mol Brain. 2015 Feb 24;8:12. doi: 10.118

   Insert

   GluN2A
   

   Use

   Lentiviral

   Tags

   Flag

   Available Since

   March 17, 2022

   Availability

   Academic Institutions and Nonprofits only

   

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10. pJEP213-Lenti-1.1Synapsin P-GFP-WPRE-pA

    Plasmid

    #62930

    Purpose

    pLenti vector backbone designed to express GFP from a 1.1Synapsin promoter .

    Depositor

    Jonathan Ploski

    Article

    Holehonnur et al Mol Brain. 2015 Feb 24;8:12. doi: 10.118

    Insert

    Green Fluorescent protein (GFP)
    

    Use

    Lentiviral

    Promoter

    1.1Synapsin and 1.3αCaMKII

    Available Since

    March 14, 2022

    Availability

    Academic Institutions and Nonprofits only

    

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11. pHCD1E

    Plasmid

    #102956

    Purpose

    gene cloning of human CD1E

    Depositor

    Gennaro De Libero, Lucia Mori

    Article

    Facciotti et al Proc Natl Acad Sci U S A. 2011 Aug 23;10

    Insert

    CD1E cDNA (CD1E Human)
    

    Use

    Cloning

    Available Since

    June 18, 2018

    Availability

    Academic Institutions and Nonprofits only

    

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12. pHMR1B

    Plasmid

    #102958

    Purpose

    gene cloning of MR1B

    Depositor

    Gennaro De Libero, Lucia Mori

    Insert

    MR1B cDNA (MR1P1 Human)
    

    Use

    Cloning

    Mutation

    Stop codon has been removed by HindIII site

    Available Since

    Nov. 20, 2017

    Availability

    Academic Institutions and Nonprofits only

    

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13. BMPR1B gRNA (BRDN0001145690)

    Plasmid

    #77488

    Purpose

    3rd generation lentiviral gRNA plasmid targeting human BMPR1B

    Depositor

    John Doench, David Root

    Article

    Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

    Insert

    BMPR1B (BMPR1B Human)
    

    Use

    CRISPR and Lentiviral

    Expression

    Mammalian

    Promoter

    hU6

    Available Since

    July 6, 2016

    Availability

    Academic Institutions and Nonprofits only

    

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14. BMPR1B gRNA (BRDN0001149274)

    Plasmid

    #77489

    Purpose

    3rd generation lentiviral gRNA plasmid targeting human BMPR1B

    Depositor

    John Doench, David Root

    Article

    Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

    Insert

    BMPR1B (BMPR1B Human)
    

    Use

    CRISPR and Lentiviral

    Expression

    Mammalian

    Promoter

    hU6

    Available Since

    July 6, 2016

    Availability

    Academic Institutions and Nonprofits only

    

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15. BMPR1B gRNA (BRDN0001148923)

    Plasmid

    #77490

    Purpose

    3rd generation lentiviral gRNA plasmid targeting human BMPR1B

    Depositor

    John Doench, David Root

    Article

    Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

    Insert

    BMPR1B (BMPR1B Human)
    

    Use

    CRISPR and Lentiviral

    Expression

    Mammalian

    Promoter

    hU6

    Available Since

    July 6, 2016

    Availability

    Academic Institutions and Nonprofits only

    

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16. BMPR1B gRNA (BRDN0001148600)

    Plasmid

    #77491

    Purpose

    3rd generation lentiviral gRNA plasmid targeting human BMPR1B

    Depositor

    John Doench, David Root

    Article

    Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

    Insert

    BMPR1B (BMPR1B Human)
    

    Use

    CRISPR and Lentiviral

    Expression

    Mammalian

    Promoter

    hU6

    Available Since

    July 6, 2016

    Availability

    Academic Institutions and Nonprofits only

    

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17. pENN.AAV.hSyn.Cre.WPRE.hGH (AAV9)

    Viral Prep

    #105553-AAV9

    Purpose

    Ready-to-use AAV9 particles produced from pENN.AAV.hSyn.Cre.WPRE.hGH (#105553). In addition to the viral particles, you will also receive purified pENN.AAV.hSyn.Cre.WPRE.hGH plasmid DNA. hSyn-driven Cre expression. These AAV preparations are suitable purity for injection into animals.

    Depositor

    James M. Wilson

    Promoter

    Syn

    Available Since

    July 26, 2018

    Availability

    Academic Institutions and Nonprofits only

18. CRISPRoff-v2.1

    Plasmid

    #167981

    Purpose

    Expresses CRISPRoff-v2.1 (DNMT3A-DNMT3L-XTEN80-dCas9-HA-2xNLS-BFP-KRAB) downstream of the CAG promoter

    Depositor

    Luke Gilbert

    Article

    Nuñez et al Cell. 2021 Apr 7. pii: S0092-8674(21)003

    Insert

    CRISPRoff-v2.1 (DNMT3A-DNMT3L-dCas9-BFP-KRAB)
    

    Tags

    2xNLS, DNMT3A-DNMT3L, HA, KRAB, and tagBFP

    Expression

    Mammalian

    Promoter

    CAG

    Available Since

    May 13, 2021

    Availability

    Academic Institutions and Nonprofits only

    

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19. pCL-Eco

    Plasmid

    #12371

    Depositor

    Inder Verma

    Article

    Naviaux et al J Virol. 1996 Aug . 70(8):5701-5.

    Insert

    gag/pol/env
    

    Use

    Retroviral

    Expression

    Mammalian

    Available Since

    Aug. 17, 2006

    Availability

    Academic Institutions and Nonprofits only

    

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20. pAAV-hSyn-DIO-hM4D(Gi)-mCherry (AAV5)

    Viral Prep

    #44362-AAV5

    Purpose

    Ready-to-use AAV5 particles produced from pAAV-hSyn-DIO-hM4D(Gi)-mCherry (#44362). In addition to the viral particles, you will also receive purified pAAV-hSyn-DIO-hM4D(Gi)-mCherry plasmid DNA. Syn-driven, Cre-dependent hM4D(Gi) receptor with an mCherry reporter for CNO-induced neuronal silencing. These AAV preparations are suitable purity for injection into animals.

    Depositor

    Bryan Roth

    Article

    Krashes et al J Clin Invest. 2011 Apr;121(4):1424-8. d

    Promoter

    Syn

    Tags

    mCherry (Cre-dependent)

    Available Since

    Dec. 1, 2016

    Availability

    Academic Institutions and Nonprofits only