We narrowed to 16,166 results for: GRN

1. ATP1A1_G4_Q118R_Std_Dual_epegRNA_tevopreQ1

   Plasmid

   #187454

   Purpose

   Coselection for prime editing in human cells. Vector for tandem expression of ATP1A1 Q118R-G4 pegRNA with a user-specified epegRNA. pU6-tevopreq1-GG-acceptor-like plasmid

   Depositor

   Yannick Doyon

   Article

   Levesque et al Nat Commun. 2022 Oct 7;13(1):5909. doi:

   Insert

   ATP1A1 G4 Q118R pegRNA (ATP1A1 Human)
   

   Use

   CRISPR; Prime editing

   Expression

   Mammalian

   Promoter

   Tandem U6 promoters

   Available Since

   July 25, 2022

   Availability

   Academic Institutions and Nonprofits only

   

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2. LCV2_LacZ_sgRNA_2

   Plasmid

   #155093

   Purpose

   lentiviral plasmid expressing Cas9 and gRNA targeting LacZ

   Depositor

   Jason Moffat

   Article

   Aregger et al Nat Metab. 2020 Jun;2(6):499-513. doi: 1

   Insert

   LacZ_sgRNA_2
   

   Use

   CRISPR and Lentiviral

   Expression

   Mammalian

   Promoter

   U6 promoter

   Available Since

   Aug. 7, 2020

   Availability

   Academic Institutions and Nonprofits only

   

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3. pLentiCRISPRv2_mSTING_scrambled_gRNA_1

   Plasmid

   #196627

   Purpose

   Scrambled control 1 for STING knock-out in murine cells.

   Depositor

   Nicolas Manel

   Article

   Jneid et al Sci Immunol. 2023 Jan 13;8(79):eabn6612.

   Insert

   mSTING scrambled gRNA 1
   

   Use

   CRISPR and Lentiviral

   Mutation

   WT

   Available Since

   Feb. 24, 2023

   Availability

   Academic Institutions and Nonprofits only

   

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4. esgRNA_NbPDS

   Plasmid

   #231147

   Purpose

   T-DNA encoding TRV2 with mobile gRNA targeting NbPDS

   Depositor

   Daniel Voytas

   Article

   Liu et al Plant Physiol. 2024 Mar 29;194(4):2229-2

   Insert

   mobile gRNA targeting NbPDS
   

   Expression

   Plant

   Promoter

   PEBV sub-genomic

   Available Since

   March 6, 2025

   Availability

   Academic Institutions and Nonprofits only

   

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5. AY22_pgRNA.R5.1

   Plasmid

   #100294

   Purpose

   CCR5-targeting gRNA expression plasmid

   Depositor

   Manuel Goncalves

   Article

   Chen et al Nat Commun. 2017 Sep 22;8(1):657. doi: 1

   Insert

   gRNA spacer
   

   Use

   CRISPR and Synthetic Biology

   Expression

   Mammalian

   Promoter

   U6 RNA Pol III promoter human snRNA

   Available Since

   Sept. 22, 2017

   Availability

   Academic Institutions and Nonprofits only

   

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6. EC2_1_dCas9_sgRNA

   Plasmid

   #163710

   Purpose

   Yeast low copy plasmid with dCas9 and sgRNA expression cassette

   Depositor

   Yvonne Nygård

   Article

   Camara et al Sci Rep. 2020 Sep 3;10(1):14605. doi: 10

   Insert

   dCas9
   

   Expression

   Yeast

   Mutation

   Point mutations D10A and H840A

   Promoter

   ScTEF1

   Available Since

   Nov. 1, 2021

   Availability

   Academic Institutions and Nonprofits only

   

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7. pX459_MCM2_sgRNA

   Plasmid

   #232730

   Purpose

   Generates MCM2 dTAG C ternimal knock-in cell lines

   Depositor

   Junjie Chen

   Insert

   MCM2 (MCM2 Human)
   

   Expression

   Bacterial and Mammalian

   Mutation

   NO

   Available Since

   March 14, 2025

   Availability

   Academic Institutions and Nonprofits only

   

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8. pX459_GINS4_gRNA

   Plasmid

   #232734

   Purpose

   Generates GINS4 dTAG C ternimal knock-in cell lines

   Depositor

   Junjie Chen

   Insert

   GINS4 (GINS4 Human)
   

   Expression

   Bacterial and Mammalian

   Mutation

   NO

   Available Since

   March 14, 2025

   Availability

   Academic Institutions and Nonprofits only

   

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9. pX459_CDC45_sgRNA

   Plasmid

   #232732

   Purpose

   Generates CDC45 dTAG C ternimal knock-in cell lines

   Depositor

   Junjie Chen

   Insert

   CDC45 (CDC45 Human)
   

   Expression

   Bacterial and Mammalian

   Mutation

   NO

   Available Since

   March 14, 2025

   Availability

   Academic Institutions and Nonprofits only

   

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10. pSPneogRNA241510+MT

    Plasmid

    #84292

    Purpose

    Express LdPBK_241510.1 and LdMT targeting gRNAs simutaneously

    Depositor

    Greg Matlashewski

    Article

    Zhang et al mSphere. 2017 Jan 18;2(1). pii: e00340-1

    Insert

    LdBPK_241510.1 targeting gRNA and LdMT targeting gRNA
    

    Use

    CRISPR; Leishmania donovani

    Promoter

    L. donovani ribosome RNA promoter

    Available Since

    Jan. 30, 2017

    Availability

    Academic Institutions and Nonprofits only

    

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11. LCV2_AAVS1_sgRNA_2

    Plasmid

    #155088

    Purpose

    lentiviral plasmid expressing Cas9 and gRNA targeting AAVS1 safe harbor locus

    Depositor

    Jason Moffat

    Article

    Aregger et al Nat Metab. 2020 Jun;2(6):499-513. doi: 1

    Insert

    AAVS1_sgRNA_2
    

    Use

    CRISPR and Lentiviral

    Expression

    Mammalian

    Promoter

    U6 promoter

    Available Since

    Aug. 7, 2020

    Availability

    Academic Institutions and Nonprofits only

    

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12. pLentiCRISPRv2_mSTING_gRNA_2

    Plasmid

    #196626

    Purpose

    Knock-out STING in murine cells, gRNA 2.

    Depositor

    Nicolas Manel

    Article

    Jneid et al Sci Immunol. 2023 Jan 13;8(79):eabn6612.

    Insert

    mSTING gRNA 2 (Sting1 Mouse)
    

    Use

    CRISPR and Lentiviral

    Mutation

    WT

    Available Since

    Feb. 24, 2023

    Availability

    Academic Institutions and Nonprofits only

    

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13. psgRNAc

    Plasmid

    #114006

    Purpose

    express sgRNA, p15A, CRM

    Depositor

    David Bikard

    Article

    Cui et al Nat Commun. 2018 May 15;9(1):1912. doi:

    Insert

    gRNA
    

    Promoter

    BBa_J23119

    Available Since

    Feb. 11, 2019

    Availability

    Academic Institutions and Nonprofits only

    

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14. pGH224_sgRNA_2xMS2_Puro

    Plasmid

    #85413

    Purpose

    hU6 driven sgRNA vector with 2xMS2 vectors with puro selectable marker

    Depositor

    Michael Bassik

    Article

    Hess et al Nat Methods. 2016 Oct 31. doi: 10.1038/n

    Insert

    puromycin resistance
    

    Use

    CRISPR and Lentiviral

    Expression

    Mammalian

    Available Since

    Dec. 15, 2016

    Availability

    Academic Institutions and Nonprofits only

    

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15. pU6_gRNA_handle_U6t

    Plasmid

    #49016

    Purpose

    gRNA expression empty vector (mammalian cells)

    Depositor

    Timothy Lu

    Article

    Farzadfard et al ACS Synth Biol. 2013 Sep 11.

    Type

    Empty backbone

    Use

    CRISPR and Synthetic Biology

    Expression

    Mammalian

    Available Since

    Oct. 29, 2013

    Availability

    Academic Institutions and Nonprofits only

    

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16. pColE1_sgRNA_pos6_AmpR

    Plasmid

    #119149

    Purpose

    Encodes sgRNA targeting position 6 in pColE1_70a_deGFP_KanR

    Depositor

    Vincent Noireaux

    Article

    Collias et al Synth Biol (Oxf). 2019 Jan 21;4(1):ysz00

    Insert

    sgRNA targeting position 6 in pColE1_70a_deGFP_KanR
    

    Use

    Crispr

    Available Since

    Nov. 28, 2018

    Availability

    Academic Institutions and Nonprofits only

    

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17. gRNA_tdtomato_reporter_1_SA-2x

    Plasmid

    #79369

    Purpose

    Assays activity of transcriptional activators fused to SA Cas9

    Depositor

    George Church

    Article

    Kiani et al Nat Methods. 2015 Sep 7. doi: 10.1038/nm

    Insert

    tdtomato
    

    Use

    CRISPR

    Expression

    Mammalian

    Available Since

    Aug. 3, 2016

    Availability

    Academic Institutions and Nonprofits only

    

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18. pENTR_AtU6p_BsaI_gRNA

    Plasmid

    #225987

    Purpose

    To make Gateway entry clone of CRISPR guide RNA under AtU6p

    Depositor

    Imran Siddiqi

    Type

    Empty backbone

    Use

    CRISPR

    Expression

    Plant

    Available Since

    Oct. 7, 2024

    Availability

    Industry, Academic Institutions, and Nonprofits

    

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19. STAGR_gRNAScaffold_mU6

    Plasmid

    #102844

    Purpose

    Can be used as PCR template for a STAgR reaction

    Depositor

    Stefan Stricker

    Article

    Breunig et al PLoS One. 2018 Apr 27;13(4):e0196015. do

    Insert

    STAgR Insert gRNAScaffold_mU6
    

    Use

    Pcr template for stagr inserts

    Promoter

    mU6

    Available Since

    Feb. 6, 2019

    Availability

    Academic Institutions and Nonprofits only

    

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20. pRPR1_gRNA_handle_RPR1t

    Plasmid

    #49014

    Purpose

    gRNA expression empty vector (yeast)

    Depositor

    Timothy Lu

    Article

    Farzadfard et al ACS Synth Biol. 2013 Sep 11.

    Type

    Empty backbone

    Use

    CRISPR and Synthetic Biology

    Expression

    Yeast

    Promoter

    pRPR1

    Available Since

    Oct. 31, 2013

    Availability

    Academic Institutions and Nonprofits only

    

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