167,820 results

1. AiP12558 - pAAV-AiE0390m_3xC2-minBG-SYFP2-WPRE3-BGHpA (Alias: CN2558)

   Plasmid

   #208141

   Purpose

   AiE0390m_3xC2 is an optimized enhancer sequence designed to drive AAV-mediated transgene expression in brain astrocytes

   Depositor

   Allen Institute for Brain Science, Jonathan Ting

   Article

   Ben-Simon et al Cell. 2025 May 16:S0092-8674(25)00513-6.

   Insert

   SYFP2
   

   Use

   AAV

   Mutation

   NA

   Promoter

   Beta Globin minimal promoter

   Available Since

   Oct. 16, 2023

   Availability

   Academic Institutions and Nonprofits only

   

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2. MSGV1-1D3-28Z.1-3 mut

   Plasmid

   #107227

   Purpose

   Anti-mouse CD19 CAR with CD3 ITAMs mutated

   Depositor

   James Kochenderfer, Steven Rosenberg

   Article

   Kochenderfer et al Blood. 2010 Nov 11;116(19):3875-86. doi:

   Insert

   1D3-28Z. 1-3 mut
   

   Use

   Retroviral

   Tags

   None

   Mutation

   None

   Available Since

   March 30, 2018

   Availability

   Academic Institutions and Nonprofits only

   

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3. Anti-TARPGamma2/Stargazin [N245/1R]

   Plasmid

   #177521

   Purpose

   Mammalian Expression Plasmid of anti-TARPGamma2/Stargazin (Rat). Derived from hybridoma N245/1.

   Depositor

   James Trimmer

   Article

   Mitchell et al Sci Rep. 2023 Sep 27;13(1):16200. doi: 1

   Insert

   anti-TARPGamma2/Stargazin (Rattus norvegicus) recombinant mouse monoclonal antibody (Cacng2 Mouse)
   

   Expression

   Mammalian

   Promoter

   Dual CMV

   Available Since

   Jan. 6, 2022

   Availability

   Academic Institutions and Nonprofits only

   

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4. pcDNA3-Lyn-AKAR4

   Plasmid

   #61620

   Purpose

   Lipid raft-targeted FRET biosensor for monitoring PKA activity

   Depositor

   Jin Zhang

   Article

   Depry et al Mol Biosyst. 2011 Jan;7(1):52-8. doi: 10

   Insert

   Lyn-AKAR4
   

   Tags

   Cerulean, N-terminal targeting sequence from Lyn …

   Expression

   Mammalian

   Promoter

   CMV

   Available Since

   March 13, 2015

   Availability

   Academic Institutions and Nonprofits only

   

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5. IDG_KCND1_OE_1

   Plasmid

   #161640

   Purpose

   Overexpresses KCND1

   Depositor

   Mike McManus

   Insert

   KCND1 (KCND1 Human)
   

   Tags

   V5

   Expression

   Mammalian

   Available Since

   Sept. 6, 2024

   Availability

   Academic Institutions and Nonprofits only

   

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6. pAM-AAV-mSncg-0.27kb-EGFP

   Plasmid

   #153185

   Purpose

   Truncated mouse gamma-synuclein (mSncg-0.27kb) promoter-mediates gene expression in retinal ganglion cells with fluorescent reporter

   Depositor

   Yang Hu

   Article

   Wang et al J Neurosci. 2020 Apr 9. pii: JNEUROSCI.0

   Type

   Empty backbone

   Use

   AAV

   Expression

   Mammalian

   Available Since

   June 25, 2020

   Availability

   Academic Institutions and Nonprofits only

   

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7. AAVS1-iPEmax-Hygro

   Plasmid

   #214020

   Purpose

   inducible PEmax system for controllable prime editing; this plasmid is used to insert PEmax prime editor in one allele of AAVS1 locus

   Depositor

   Ting Zhou

   Article

   Wu et al Nat Commun. 2024 Dec 30;15(1):10824. doi

   Insert

   PEmax
   

   Expression

   Mammalian

   Promoter

   TRE-tight

   Available Since

   June 6, 2024

   Availability

   Academic Institutions and Nonprofits only

   

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8. pESR1.1.0-gDNA

   Plasmid

   #112433

   Purpose

   CRISPR plasmid for expression of Cas9 and gRNA targeting human transcription factor ESR1

   Depositor

   Kevin White

   Insert

   ESR1 (ESR1 Human)
   

   Use

   CRISPR

   Expression

   Mammalian

   Available Since

   Dec. 7, 2018

   Availability

   Academic Institutions and Nonprofits only

   

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9. pAAV-hSyn Con/Fon hChR2(H134R)-EYFP (AAV9)

   Viral Prep

   #55645-AAV9

   Purpose

   Ready-to-use AAV9 particles produced from pAAV-hSyn Con/Fon hChR2(H134R)-EYFP (#55645). In addition to the viral particles, you will also receive purified pAAV-hSyn Con/Fon hChR2(H134R)-EYFP plasmid DNA. Synapsin-driven, Cre-dependent and Flp-dependent channelrhodopsin-EYFP expression for optogenetic activation. These AAV preparations are suitable purity for injection into animals.

   Depositor

   Karl Deisseroth

   Article

   Fenno et al Nat Methods. 2014 Jul;11(7):763-72. doi:

   Promoter

   Syn

   Tags

   EYFP (Cre- and Flp-dependent)

   Available Since

   June 8, 2020

   Availability

   Academic Institutions and Nonprofits only

10. pBS mPrx1 (CT#640)

    Plasmid

    #13961

    Depositor

    Cliff Tabin

    Article

    Logan et al Genesis. 2002 Jun . 33(2):77-80.

    Insert

    Prx1 promoter (Prrx1 Mouse)
    

    Expression

    Bacterial

    Available Since

    Feb. 15, 2007

    Availability

    Academic Institutions and Nonprofits only

11. mEmerald-Myopalladin-C-14

    Plasmid

    #54188

    Purpose

    Localization: Cytoskeleton , Excitation: 487, Emission: 509

    Depositor

    Michael Davidson

    Insert

    Myopalladin (MYPN Human)
    

    Tags

    mEmerald

    Expression

    Mammalian

    Promoter

    CMV

    Available Since

    July 25, 2014

    Availability

    Industry, Academic Institutions, and Nonprofits

12. mEos4a-Actin-C-18

    Plasmid

    #57488

    Purpose

    Localization: Actin, Excitation: 505 / 569, Emission: 516 / 581

    Depositor

    Michael Davidson, Loren Looger

    Insert

    Actin (ACTB Human)
    

    Tags

    mEos4a

    Expression

    Mammalian

    Promoter

    CMV

    Available Since

    March 12, 2015

    Availability

    Industry, Academic Institutions, and Nonprofits

    

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13. pAAV-CaMKIIa-hM4D(Gi)-mCherry (AAV9)

    Viral Prep

    #50477-AAV9

    Purpose

    Ready-to-use AAV9 particles produced from pAAV-CaMKIIa-hM4D(Gi)-mCherry (#50477). In addition to the viral particles, you will also receive purified pAAV-CaMKIIa-hM4D(Gi)-mCherry plasmid DNA. CaMKIIa-driven hM4D(Gi) receptor with an mCherry reporter for CNO-induced neuronal silencing. These AAV preparations are suitable purity for injection into animals.

    Depositor

    Bryan Roth

    Promoter

    CaMKII

    Tags

    mCherry

    Available Since

    Jan. 26, 2021

    Availability

    Academic Institutions and Nonprofits only

14. pHAGE-XPO1-R749Q

    Plasmid

    #116709

    Purpose

    Lentiviral expression of XPO1 R749Q

    Depositor

    Kenneth Scott, Gordon Mills

    Article

    Ng et al Cancer Cell. 2018 Mar 12;33(3):450-462.e

    Insert

    XPO1 (XPO1 Human)
    

    Use

    Lentiviral

    Mutation

    R749Q

    Available Since

    March 14, 2019

    Availability

    Academic Institutions and Nonprofits only

    

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15. pDIRECT_26G

    Plasmid

    #91149

    Purpose

    Direct Cloning, Type: T-DNA, Engineering Reagent: ZmUbi:TaCas9_dead + TaU6:gRNA , Plant Selection: PvUbi2:bar

    Depositor

    Daniel Voytas

    Article

    Cermak et al Plant Cell. 2017 May 18. pii: tpc.00922.

    Insert

    Engineering Reagent: ZmUbi:TaCas9_dead + TaU6:gRNA
    

    Use

    CRISPR

    Expression

    Plant

    Mutation

    D10A, H840A

    Available Since

    July 7, 2017

    Availability

    Academic Institutions and Nonprofits only

    

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16. CDK2 gRNA (BRDN0001148950)

    Plasmid

    #77193

    Purpose

    3rd generation lentiviral gRNA plasmid targeting human CDK2

    Depositor

    David Root, John Doench

    Article

    Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

    Insert

    CDK2 (CDK2 Human)
    

    Use

    CRISPR and Lentiviral

    Expression

    Mammalian

    Promoter

    hU6

    Available Since

    July 6, 2016

    Availability

    Academic Institutions and Nonprofits only

    

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17. pDONR221-SLC38A5_STOP

    Plasmid

    #161284

    Purpose

    Gateway entry clone with codon-optimized ORF sequence for subcloning into custom expression vectors. Contains a STOP codon at the end of the codon-optimized ORF sequence.

    Depositor

    Giulio Superti-Furga, RESOLUTE Consortium

    Article

    Superti-Furga et al Nat Rev Drug Discov. 2020 Jul;19(7):429-

    Insert

    SLC38A5 (SLC38A5 Human)
    

    Expression

    Mammalian

    Available Since

    Sept. 15, 2021

    Availability

    Industry, Academic Institutions, and Nonprofits

    

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18. pGGD005

    Plasmid

    #48853

    Purpose

    Provides linker:BFP as GreenGate C-terminal tag module.

    Depositor

    Jan Lohmann

    Article

    Lampropoulos et al PLoS One. 2013 Dec 20;8(12):e83043. doi:

    Insert

    Linker:BFP
    

    Use

    Golden gate compatible cloning vector

    Available Since

    Jan. 7, 2014

    Availability

    Academic Institutions and Nonprofits only

    

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19. Anti-TARPGamma2/4/8 [N245/36R]

    Plasmid

    #177522

    Purpose

    Mammalian Expression Plasmid of anti-TARPGamma2/4/8 (Rat). Derived from hybridoma N245/36.

    Depositor

    James Trimmer

    Article

    Mitchell et al Sci Rep. 2023 Sep 27;13(1):16200. doi: 1

    Insert

    anti-TARPGamma2/4/8 (Rattus norvegicus) recombinant mouse monoclonal antibody (Tarp Mouse)
    

    Expression

    Mammalian

    Promoter

    Dual CMV

    Available Since

    Jan. 6, 2022

    Availability

    Academic Institutions and Nonprofits only

    

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20. pD649-HAsp-ROBO3-Fc(DAPA)-AviTag-6xHis

    Plasmid

    #156997

    Purpose

    Mammalian expression of cell-surface protein extracellular domain fused to Fc(DAPA)-Avi-6xHis. Protein is secreted from cells.

    Depositor

    Chris Garcia

    Article

    Wojtowicz et al Cell. 2020 Aug 20;182(4):1027-1043.e17.

    Insert

    ROBO3 (ROBO3 Human)
    

    Tags

    Fc(DAPA)-AviTag-6xHis

    Expression

    Mammalian

    Mutation

    Fc region of human IgG contains D265A and P329A m…

    Promoter

    CMV/SP6

    Available Since

    March 8, 2023

    Availability

    Academic Institutions and Nonprofits only

    

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21. IFN-Beta_pGL3

    Plasmid

    #102597

    Purpose

    IFN-beta promoter driving luciferase. Use in IFN reporter assay.

    Depositor

    Nicolas Manel

    Article

    Gentili et al Science. 2015 Sep 11;349(6253):1232-6. d

    Insert

    Human IFN-Beta promoter (IFNB1 Human)
    

    Use

    Luciferase

    Tags

    luciferase

    Expression

    Mammalian

    Available Since

    Jan. 18, 2018

    Availability

    Academic Institutions and Nonprofits only

    

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22. mTurquoise-ZO1-C-14

    Plasmid

    #55588

    Purpose

    Localization: Tight Junctions, Excitation: 434, Emission: 474

    Depositor

    Michael Davidson

    Insert

    ZO1 (TJP1 Human)
    

    Tags

    mTurquoise

    Expression

    Mammalian

    Promoter

    CMV

    Available Since

    Oct. 10, 2014

    Availability

    Industry, Academic Institutions, and Nonprofits

23. pMOS031: superecliptic pHluorin (endoplasmic reticulum)

    Plasmid

    #163051

    Purpose

    superecliptic pHluorin (endoplasmic reticulum)

    Depositor

    Adam Cohen

    Article

    Werley et al Nat Commun. 2020 Aug 4;11(1):3881. doi:

    Insert

    superecliptic pHluorin
    

    Use

    Lentiviral

    Expression

    Mammalian

    Promoter

    CMV

    Available Since

    March 9, 2021

    Availability

    Academic Institutions and Nonprofits only

    

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24. pShuttle-EGFP-CLASP2 340-1362 9xS/A

    Plasmid

    #24373

    Depositor

    Torsten Wittmann

    Article

    Kumar et al J Cell Biol. 2009 Mar 23. 184(6):895-908

    Insert

    CLASP2 (340-1362) 9xS/A (CLASP2 Human)
    

    Tags

    EGFP

    Expression

    Mammalian

    Mutation

    Nonphosphorylatable CLASP2 deletion mutant. M…

    Available Since

    June 29, 2010

    Availability

    Academic Institutions and Nonprofits only

    

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25. pDONR223_MAP2K1_WT

    Plasmid

    #81920

    Purpose

    Gateway Donor vector containing MAP2K1 , part of the Target Accelerator Plasmid Collection.

    Depositor

    William Hahn, Jesse Boehm, David Root

    Article

    Kim et al Cancer Discov. 2016 Jul;6(7):714-26. doi

    Insert

    MAP2K1 (MAP2K1 Human)
    

    Use

    Gateway entry vector

    Mutation

    I310N

    Promoter

    None

    Available Since

    April 24, 2017

    Availability

    Academic Institutions and Nonprofits only

    

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26. pMOS030: ratiometric pHluorin (endoplasmic reticulum)

    Plasmid

    #163054

    Purpose

    ratiometric pHluorin (endoplasmic reticulum)

    Depositor

    Adam Cohen

    Article

    Werley et al Nat Commun. 2020 Aug 4;11(1):3881. doi:

    Insert

    ratiometric pHluorin
    

    Use

    Lentiviral

    Expression

    Mammalian

    Promoter

    CMV

    Available Since

    March 9, 2021

    Availability

    Academic Institutions and Nonprofits only

    

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27. pDONR223_MAP2K1_p.P124S

    Plasmid

    #81703

    Purpose

    Gateway Donor vector containing MAP2K1, part of the Target Accelerator Plasmid Collection.

    Depositor

    William Hahn, Jesse Boehm, David Root

    Article

    Kim et al Cancer Discov. 2016 Jul;6(7):714-26. doi

    Insert

    MAP2K1 (MAP2K1 Human)
    

    Use

    Gateway entry vector

    Mutation

    P124S; I310N

    Promoter

    None

    Available Since

    April 24, 2017

    Availability

    Academic Institutions and Nonprofits only

    

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28. mCherry VPS37b

    Plasmid

    #245030

    Purpose

    Protein localization of human wild-type VPS37b in cells

    Depositor

    Thomas Martin

    Insert

    VPS37b (VPS37B Human)
    

    Tags

    mCherry

    Expression

    Bacterial

    Available Since

    Sept. 30, 2025

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

29. pAAV.CAG.(cyto).iGlucoSnFR2.mIRFP670nano3

    Plasmid

    #244072

    Purpose

    Cytosolic expression of green glucose sensor with non-responsive mIRFP

    Depositor

    Tim Brown, HHMI-JRC Tool Translation Team

    Insert

    iGlucoSnFR2.mIRFP670nano3
    

    Use

    AAV

    Tags

    mIRFP670nano3

    Available Since

    Sept. 24, 2025

    Availability

    Academic Institutions and Nonprofits only

    

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30. pME-V5-mClover-KRAS4A-G12D (JDW 813)

    Plasmid

    #242567

    Purpose

    Gateway middle entry clone containing an mClover3 fused human KRAS4A G12D.

    Depositor

    Joshua Wythe

    Article

    Gillespie et al bioRxiv [Preprint]. 2024 Jul 13:2024.07.

    Insert

    KRAS4A-G12D (KRAS Human)
    

    Use

    Gateway subcloning

    Available Since

    Sept. 11, 2025

    Availability

    Academic Institutions and Nonprofits only

    

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31. pFUW-TetO-Cbfa2t3

    Plasmid

    #207206

    Purpose

    doxycycline-inducible expression of Mouse Cbfa2t3 in mammalian cells

    Depositor

    Filipe Pereira

    Article

    Henriques-Oliveira et al Immunity. 58, 1-20. October 2025.

    Insert

    pFUW-TetO-CBFA2T3
    

    Use

    Lentiviral

    Expression

    Mammalian

    Promoter

    CMV

    Available Since

    Aug. 29, 2025

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

32. pFUW COX8ASig-Lemon

    Plasmid

    #239560

    Purpose

    Expression and mitochondrial localization of Lemon, a pH biosensor

    Depositor

    Joel Blanchard, Tim Ahfeldt

    Article

    et al iScience 28 (2025)

    Insert

    Lemon
    

    Use

    Lentiviral

    Promoter

    UbC

    Available Since

    June 30, 2025

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

33. pRCA360 - pBA904 Puro-T2A-GFP

    Plasmid

    #238164

    Purpose

    Lentiviral CRISPR guide vector expressing a non-targeting sgRNA with cs1 incorporated in the loop of the sgRNA constant region for 10X Direct Capture

    Depositor

    Thomas Norman

    Article

    Southard et al Nat Genet. 2025 Aug 6. doi: 10.1038/s415

    Insert

    Non-targeting sgRNA
    

    Use

    Lentiviral

    Tags

    GFP

    Available Since

    June 3, 2025

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

34. pRSFDUET-1_VNp-anti-Lysozyme fAb-BiFC

    Plasmid

    #214950

    Purpose

    Bacterial expression of anti-chicken lysozyme Fab light and heavy chain VNp fusions. Each chain is fused to separate halves of a BiFC protein -Venus fluorescence signifies Hc/Lc heterodimer formation.

    Depositor

    Dan Mulvihill

    Article

    Baker et al Open Biol. 2025 Feb;15(2):240229. doi: 1

    Inserts

    VNp-anti-Lysozyme Fab heavy chain amino-BiFC fusion
    VNp-anti-Lysozyme Fab light chain amino-BiFC fusion
    

    Tags

    6xHis, Amino half of venus BIFC fragment, Carboxy…

    Expression

    Bacterial

    Promoter

    T7

    Available Since

    Jan. 24, 2025

    Availability

    Academic Institutions and Nonprofits only

    

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35. pLViP-LifeAct-TagRFPT

    Plasmid

    #229700

    Purpose

    Lentiviral expression of LifeAct-TagRFPT in mammalian cells

    Depositor

    Alpha Yap

    Article

    Noordstra et al Dev Cell. 2023 Sep 25;58(18):1748-1763.e

    Insert

    Synthetic construct LifeAct-mTurquoise gene
    

    Use

    Lentiviral

    Tags

    TagRFPT

    Expression

    Mammalian

    Promoter

    CMV promoter

    Available Since

    Jan. 16, 2025

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

36. pCA528 IST1 (1-366)

    Plasmid

    #193039

    Purpose

    Bacterial expression plasmid for full-length IST1 (1-366).

    Depositor

    Wesley Sundquist

    Article

    Paine et al Elife. 2023 Sep 29;12:e84515. doi: 10.75

    Insert

    IST1 (IST1 Human)
    

    Tags

    6xHis-Sumo

    Expression

    Bacterial

    Promoter

    T7

    Available Since

    Dec. 9, 2024

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

37. DRH031_ AAV-SIO-nEF-WT-THR

    Plasmid

    #225090

    Purpose

    Cre-dependent expression of wild-type thyroid receptor beta (THRB, human) in neurons driven by nEF promoter.

    Depositor

    Bernardo Sabatini

    Article

    Hochbaum et al Cell. 2024 Oct 3;187(20):5679-5697.e23.

    Insert

    DN-THRB (THRB Human)
    

    Use

    AAV

    Available Since

    Oct. 21, 2024

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

38. DRH032_ AAV-SIO-nEF-DN-THR

    Plasmid

    #225091

    Purpose

    Cre-dependent expression of dominant-negative thyroid receptor beta (THRB, human) in neurons driven by nEF promoter.

    Depositor

    Bernardo Sabatini

    Article

    Hochbaum et al Cell. 2024 Oct 3;187(20):5679-5697.e23.

    Insert

    WT-THRB (THRB Human)
    

    Use

    AAV

    Available Since

    Oct. 21, 2024

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

39. pCfb12620

    Plasmid

    #219928

    Purpose

    PrTPI with the overhangs for SapI restriction site can be insert into the base plasmid of TUNEYALI

    Depositor

    Irina Borodina

    Insert

    Promoter TPI
    

    Expression

    Yeast

    Available Since

    June 11, 2024

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

40. AAVS1-iPE2-Hygro

    Plasmid

    #214019

    Purpose

    inducible PE2 system for controllable prime editing; this plasmid is used to insert PE2 prime editor in one allele of AAVS1 locus

    Depositor

    Ting Zhou

    Article

    Wu et al Nat Commun. 2024 Dec 30;15(1):10824. doi

    Insert

    PE2
    

    Expression

    Mammalian

    Promoter

    TRE-tight

    Available Since

    June 6, 2024

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge