We narrowed to 51,423 results for: son

1. Chr1q_Centromere-Targeting_gRNA

   Plasmid

   #195125

   Purpose

   gRNA targeting centromere-proximal location on Chromosome 1q in a third generation Cas9 backbone with GFP

   Depositor

   Jason Sheltzer

   Article

   Girish et al Science. 2023 Jul 6:eadg4521. doi: 10.11

   Insert

   Chr1q gRNA
   

   Expression

   Mammalian

   Available Since

   Feb. 3, 2023

   Availability

   Academic Institutions and Nonprofits only

   

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2. Chr7_Centromere-Targeting_gRNA

   Plasmid

   #195129

   Purpose

   dual gRNA vector targeting centromere-proximal locations on Chromosome 7p and 7q in a third generation Cas9 backbone with GFP

   Depositor

   Jason Sheltzer

   Article

   Girish et al Science. 2023 Jul 6:eadg4521. doi: 10.11

   Insert

   Chr7 gRNA
   

   Expression

   Mammalian

   Available Since

   Feb. 6, 2023

   Availability

   Academic Institutions and Nonprofits only

   

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3. lentiCRISPRv2.sgNf1.1

   Plasmid

   #91895

   Purpose

   sgNf1.1 for Nf1 deletion

   Depositor

   Wen Xue

   Article

   Song et al Gastroenterology. 2017 Apr;152(5):1161-1

   Insert

   sgNf1.1
   

   Use

   Lentiviral and Mouse Targeting

   Expression

   Mammalian

   Available Since

   March 16, 2018

   Availability

   Academic Institutions and Nonprofits only

   

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4. lentiCRISPRv2.sgNf1.4

   Plasmid

   #92029

   Purpose

   sgNf1.4 for Nf1 deletion

   Depositor

   Wen Xue

   Article

   Song et al Gastroenterology. 2017 Apr;152(5):1161-1

   Insert

   sgNf1.4 for Nf1 deletion
   

   Use

   Lentiviral and Mouse Targeting

   Expression

   Mammalian

   Available Since

   April 12, 2018

   Availability

   Academic Institutions and Nonprofits only

   

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5. Chr8q_Centromere-Targeting_gRNA

   Plasmid

   #195128

   Purpose

   gRNA targeting centromere-proximal location on Chromosome 8q in a third generation Cas9 backbone with GFP

   Depositor

   Jason Sheltzer

   Article

   Girish et al Science. 2023 Jul 6:eadg4521. doi: 10.11

   Insert

   Chr8q gRNA
   

   Expression

   Mammalian

   Available Since

   Feb. 3, 2023

   Availability

   Academic Institutions and Nonprofits only

   

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6. pLVX-Puro-TDP-43-A90V

   Plasmid

   #133754

   Purpose

   Lentiviral expression of human TDP-43 A90V disease mutant in mammalian cells.

   Depositor

   Shawn Ferguson

   Article

   Roczniak-Ferguson et al Life Sci Alliance. 2019 Sep 16;2(5). pii

   Insert

   TARDBP (TARDBP Human)
   

   Use

   Lentiviral

   Expression

   Mammalian

   Mutation

   Changed alanine 90 to valine

   Promoter

   CMV

   Available Since

   Dec. 2, 2019

   Availability

   Academic Institutions and Nonprofits only

   

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7. pLVX-Puro-TDP-43-P112H

   Plasmid

   #133760

   Purpose

   Lentiviral expression of human TDP-43 P112H disease mutant in mammalian cells.

   Depositor

   Shawn Ferguson

   Article

   Roczniak-Ferguson et al Life Sci Alliance. 2019 Sep 16;2(5). pii

   Insert

   TDP-43 (TARDBP Human)
   

   Use

   Lentiviral

   Expression

   Mammalian

   Mutation

   Changed proline 112 to histidine.

   Promoter

   CMV

   Available Since

   Jan. 7, 2020

   Availability

   Academic Institutions and Nonprofits only

   

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8. Rosa26_gRNA

   Plasmid

   #196138

   Purpose

   gRNA targeting the Rosa26 locus in a thid generation Cas9 backbone with TagBFP2

   Depositor

   Jason Sheltzer

   Article

   Girish et al Science. 2023 Jul 6:eadg4521. doi: 10.11

   Insert

   Rosa26 gRNA
   

   Use

   CRISPR and Lentiviral

   Expression

   Mammalian

   Available Since

   March 8, 2023

   Availability

   Academic Institutions and Nonprofits only

   

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9. pLVX-Puro-TDP-43-D169G

   Plasmid

   #133757

   Purpose

   Lentiviral expression of human TDP-43 D169G disease mutant in mammalian cells.

   Depositor

   Shawn Ferguson

   Article

   Roczniak-Ferguson et al Life Sci Alliance. 2019 Sep 16;2(5). pii

   Insert

   TDP-43 (TARDBP Human)
   

   Use

   Lentiviral

   Expression

   Mammalian

   Mutation

   Changed aspartate 169 to glycine.

   Promoter

   CMV

   Available Since

   Dec. 2, 2019

   Availability

   Academic Institutions and Nonprofits only

   

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10. OR6K6_Deletion_gRNA2

    Plasmid

    #195196

    Purpose

    dual gRNAs for deletion of OR6K6 in a third generation Cas9 backbone with GFP

    Depositor

    Jason Sheltzer

    Article

    Girish et al Science. 2023 Jul 6:eadg4521. doi: 10.11

    Insert

    OR6K6 dual gRNA (OR6K6 Human)
    

    Expression

    Mammalian

    Available Since

    Feb. 14, 2023

    Availability

    Academic Institutions and Nonprofits only

    

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11. OR6K6_Deletion_gRNA1

    Plasmid

    #195195

    Purpose

    dual gRNAs for deletion of OR6K6 in a third generation Cas9 backbone with GFP

    Depositor

    Jason Sheltzer

    Article

    Girish et al Science. 2023 Jul 6:eadg4521. doi: 10.11

    Insert

    OR6K6 dual gRNA (OR6K6 Human)
    

    Expression

    Mammalian

    Available Since

    Feb. 14, 2023

    Availability

    Academic Institutions and Nonprofits only

    

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12. OR6K6_Deletion_gRNA3

    Plasmid

    #195197

    Purpose

    dual gRNAs for deletion of OR6K6 in a third generation Cas9 backbone with GFP

    Depositor

    Jason Sheltzer

    Article

    Girish et al Science. 2023 Jul 6:eadg4521. doi: 10.11

    Insert

    OR6K6 dual gRNA (OR6K6 Human)
    

    Expression

    Mammalian

    Available Since

    Feb. 14, 2023

    Availability

    Academic Institutions and Nonprofits only

    

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13. SVA-lncRNA AK057321 shRNA 1S scramble

    Plasmid

    #202837

    Purpose

    Lentiviral vector that expresses a scrambled control shRNA for SVA-lncRNA AK057321 shRNA 1S

    Depositor

    Matthew Anderson

    Article

    Nadler et al Commun Biol. 2023 Mar 30;6(1):347. doi:

    Insert

    SVA-lncRNA AK057321 shRNA 1S scramble control
    

    Use

    Lentiviral

    Expression

    Mammalian

    Promoter

    6

    Available Since

    July 21, 2023

    Availability

    Academic Institutions and Nonprofits only

    

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14. SVA-lncRNA AK057321 shRNA 2S scramble

    Plasmid

    #202839

    Purpose

    Lentiviral vector that expresses a scrambled control shRNA for SVA-lncRNA AK057321 shRNA 2S

    Depositor

    Matthew Anderson

    Article

    Nadler et al Commun Biol. 2023 Mar 30;6(1):347. doi:

    Insert

    SVA-lncRNA AK057321 shRNA 2S scramble control
    

    Use

    Lentiviral

    Expression

    Mammalian

    Promoter

    U6

    Available Since

    July 7, 2023

    Availability

    Academic Institutions and Nonprofits only

    

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15. pGL3-luciferase-reporter-POFUT2-SVA

    Plasmid

    #202831

    Purpose

    pGL3 luciferase reporter with POFUT2 SVA cloned upstream of SV40 promoter to test effects of SVA insertion on luciferase expression

    Depositor

    Matthew Anderson

    Article

    Nadler et al Commun Biol. 2023 Mar 30;6(1):347. doi:

    Insert

    POFUT2 intronic SVA
    

    Use

    Luciferase

    Expression

    Mammalian

    Promoter

    SV40

    Available Since

    July 7, 2023

    Availability

    Academic Institutions and Nonprofits only

    

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16. pGL3-luciferase-reporter-HTT-SVA

    Plasmid

    #202833

    Purpose

    pGL3 luciferase reporter with HTT SVA cloned upstream of SV40 promoter to test effects of SVA insertion on luciferase expression

    Depositor

    Matthew Anderson

    Article

    Nadler et al Commun Biol. 2023 Mar 30;6(1):347. doi:

    Insert

    HTT intronic SVA
    

    Use

    Luciferase

    Expression

    Mammalian

    Promoter

    SV40

    Available Since

    July 7, 2023

    Availability

    Academic Institutions and Nonprofits only

    

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17. pGL3-luciferase-reporter-CHAF1B-SVA

    Plasmid

    #202829

    Purpose

    pGL3 luciferase reporter with CHAF1B SVA cloned upstream of SV40 promoter to test effects of SVA insertion on luciferase expression

    Depositor

    Matthew Anderson

    Article

    Nadler et al Commun Biol. 2023 Mar 30;6(1):347. doi:

    Insert

    CHAF1B intronic SVA
    

    Use

    Luciferase

    Expression

    Mammalian

    Promoter

    SV40

    Available Since

    July 7, 2023

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

18. SVA-lncRNA AK057321 shRNA 1A scramble control

    Plasmid

    #202835

    Purpose

    Lentiviral vector that expresses a scrambled control shRNA for SVA-lncRNA AK057321 shRNA 1A

    Depositor

    Matthew Anderson

    Article

    Nadler et al Commun Biol. 2023 Mar 30;6(1):347. doi:

    Insert

    pLVX-SVA-lncRNA shRNA 1A scramble control
    

    Use

    Lentiviral

    Expression

    Mammalian

    Promoter

    U6

    Available Since

    July 6, 2023

    Availability

    Academic Institutions and Nonprofits only

    

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19. pLenti-EML4-ALK variant 3a I1171N/D1203N

    Plasmid

    #183833

    Purpose

    Express EML4-ALK fusion variant 3a (E6a;A20) harboring ALK I1171N/D1203N mutation in mammalian cells

    Depositor

    Aaron Hata

    Article

    Shiba-Ishii et al Nat Cancer. 2022 Jun 20. pii: 10.1038/s4

    Inserts

    ALK Receptor Tyrosine Kinase (ALK Human)
    EMAP Like 4 (EML4 Human)
    

    Use

    Lentiviral

    Tags

    The fusion protein of EML4 exon 1-6a and ALK exon…

    Expression

    Mammalian

    Mutation

    I1171N/D1203N

    Promoter

    CMV

    Available Since

    June 22, 2022

    Availability

    Academic Institutions and Nonprofits only

    

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20. Self-targeting epegRNA library, +5 G>H (lDS004)

    Pooled Library

    #227707

    Purpose

    CRISPR guide RNA library for prime editing

    Depositor

    Brittany Adamson

    Article

    Cirincione et al Nat Methods. 2024 Nov 19. doi: 10.1038/s

    Expression

    Mammalian

    Use

    Lentiviral

    Available Since

    Jan. 23, 2025

    Availability

    Academic Institutions and Nonprofits only