Purpose
encodes S. pyogenes dCas9 with c-terminal fusion of human p300 HAT core (aa 1048-1664; inactivating mutation D1399Y) driven by CMV promoter
Insert
S.pyogenes dCas9 with c-terminal human p300 Core effector fusion (aa 1048-1664 of human p300) (
EP300 Synthetic, S. pyogenes, Human)
Use
CRISPR and Synthetic Biology
Tags
Flag, HA, and SV40 NLS
Mutation
D10A; H840A in S.pyogenes Cas9; D1399Y mutation i…
Available Since
April 10, 2015
Availability
Academic Institutions and Nonprofits only