We narrowed to 67,891 results for: TOR

1. CAG-VEGF120-T2A-mCherry

   Plasmid

   #229134

   Purpose

   Retrovirus driving overexpression of VEGF120 plus mCherry reporter

   Depositor

   Elizabeth Kirby

   Article

   Miller et al Mol Psychiatry. 2024 Nov 11. doi: 10.103

   Inserts

   VEGF120 (Vegfa Mouse)
   mCherry
   

   Use

   Retroviral

   Expression

   Mammalian

   Available Since

   Jan. 22, 2025

   Availability

   Academic Institutions and Nonprofits only

   

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2. Lenti-SAM-Puro

   Plasmid

   #198713

   Purpose

   For expression of guide RNAs and the SAM transcriptional activator for CRISPRa in mammalian cells.

   Depositor

   Tyler Jacks

   Article

   Gaglia et al Cancer Cell. 2023 May 8;41(5):871-886.e1

   Inserts

   U6-MS2-gRNAscaffold
   EF1a-MPH-Puro
   

   Use

   CRISPR and Lentiviral

   Expression

   Mammalian

   Promoter

   EF1a and U6

   Available Since

   Jan. 7, 2025

   Availability

   Academic Institutions and Nonprofits only

   

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3. Lenti-SAM-Cre

   Plasmid

   #198714

   Purpose

   For expression of guide RNAs, the SAM transcriptional activator for CRISPRa and Cre in mammalian cells

   Depositor

   Tyler Jacks

   Article

   Gaglia et al Cancer Cell. 2023 May 8;41(5):871-886.e1

   Inserts

   U6-MS2-gRNAscaffold
   Pgk-MPH-Cre
   

   Use

   Cre/Lox and Lentiviral

   Expression

   Mammalian

   Promoter

   Pgk and U6

   Available Since

   Jan. 7, 2025

   Availability

   Academic Institutions and Nonprofits only

   

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4. pPBpuro-miRFP703-eDHFR(69K6)-cRaf

   Plasmid

   #209919

   Purpose

   Mammalian expression of cRaf fused to miRFP703-eDHFR(69K6)

   Depositor

   Michiyuki Matsuda

   Article

   Deguchi et al Cell Rep. 2024 Nov 14;43(11):114986. doi

   Insert

   miRFP703-eDHFR(69K6)-cRaf (RAF1 Human)
   

   Expression

   Mammalian

   Available Since

   Nov. 18, 2024

   Availability

   Academic Institutions and Nonprofits only

   

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5. pPBbleo-miRFP703-eDHFR(69K6)-cRaf

   Plasmid

   #209920

   Purpose

   Mammalian expression of cRaf fused to miRFP703-eDHFR(69K6)

   Depositor

   Michiyuki Matsuda

   Article

   Deguchi et al Cell Rep. 2024 Nov 14;43(11):114986. doi

   Insert

   miRFP703-eDHFR(69K6)-cRaf (RAF1 Human)
   

   Expression

   Mammalian

   Available Since

   Nov. 18, 2024

   Availability

   Academic Institutions and Nonprofits only

   

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6. pPBbsr2-miRFP703-eDHFR(69K6)-cRaf

   Plasmid

   #209921

   Purpose

   Mammalian expression of cRaf fused to miRFP703-eDHFR(69K6)

   Depositor

   Michiyuki Matsuda

   Article

   Deguchi et al Cell Rep. 2024 Nov 14;43(11):114986. doi

   Insert

   miRFP703-eDHFR(69K6)-cRaf (RAF1 Human)
   

   Expression

   Mammalian

   Available Since

   Nov. 18, 2024

   Availability

   Academic Institutions and Nonprofits only

   

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7. pPICZ:K2P2.1(mTREK-1)Cryst S112C

   Plasmid

   #224780

   Purpose

   Pichia pastoris expression vector for generating mouse TREK-1(21S-322T) + 3C cleavable site + eGFP + 10x His under the AOX1 promoter

   Depositor

   Dan Minor

   Article

   Deal et al Cell Chem Biol. 2024 Jul 18;31(7):1305-1

   Insert

   Potassium channel subfamily K member 2 (Kcnk2 Mouse)
   

   Expression

   Yeast

   Mutation

   K84R / Q85E / T86K / I88L / A89R / Q90A / A92P / …

   Promoter

   AOX1 promoter

   Available Since

   Sept. 13, 2024

   Availability

   Academic Institutions and Nonprofits only

   

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8. pBK1297-AAV-EFSNC-dCjCas9-HP1b(79-173)

   Plasmid

   #223142

   Purpose

   Expression of truncated HP1b with dCjCas9 and empty gRNA scaffold

   Depositor

   Boris Kantor

   Article

   Kantor et al bioRxiv [Preprint]. 2024 May 19:2023.04.

   Insert

   HP1b (CBX1 Human)
   

   Use

   AAV and CRISPR

   Tags

   3xFLAG

   Expression

   Mammalian

   Mutation

   Encodes aa 79-173

   Promoter

   EF1a

   Available Since

   Aug. 28, 2024

   Availability

   Academic Institutions and Nonprofits only

   

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9. pBK1298-AAV-EFSNC-dCjCas9-HP1bNH(111-173)

   Plasmid

   #223143

   Purpose

   Expression of truncated HP1b with dCjCas9 and empty gRNA scaffold

   Depositor

   Boris Kantor

   Article

   Kantor et al bioRxiv [Preprint]. 2024 May 19:2023.04.

   Insert

   HP1b (CBX1 Human)
   

   Use

   AAV and CRISPR

   Tags

   3xFLAG

   Expression

   Mammalian

   Mutation

   Encodes aa 111-173

   Promoter

   EF1a

   Available Since

   Aug. 23, 2024

   Availability

   Academic Institutions and Nonprofits only

   

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10. pBK1306-AAV-EFSNC-dSaCas9-HP1aNH(115-177)

    Plasmid

    #223151

    Purpose

    Expression of truncated HP1a with dSaCas9 and empty gRNA scaffold

    Depositor

    Boris Kantor

    Article

    Kantor et al bioRxiv [Preprint]. 2024 May 19:2023.04.

    Insert

    HP1a (CBX5 Human)
    

    Use

    AAV and CRISPR

    Tags

    3xFLAG

    Expression

    Mammalian

    Mutation

    Encodes aa 115-177

    Promoter

    EF1a

    Available Since

    Aug. 23, 2024

    Availability

    Academic Institutions and Nonprofits only

    

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11. pBK1296-AAV-EFSNC-dCjCas9-HP1aNH(115-177)

    Plasmid

    #223141

    Purpose

    Expression of truncated HP1a with dCjCas9 and empty gRNA scaffold

    Depositor

    Boris Kantor

    Article

    Kantor et al bioRxiv [Preprint]. 2024 May 19:2023.04.

    Insert

    HP1a (CBX5 Human)
    

    Use

    AAV and CRISPR

    Tags

    3xFLAG

    Expression

    Mammalian

    Mutation

    Encodes aa 115-177

    Promoter

    EF1a

    Available Since

    Aug. 23, 2024

    Availability

    Academic Institutions and Nonprofits only

    

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12. pBK1308-AAV-EFSNC-dSaCas9-HP1bNH(111-173)

    Plasmid

    #223153

    Purpose

    Expression of truncated HP1b with dSaCas9 and empty gRNA scaffold

    Depositor

    Boris Kantor

    Article

    Kantor et al bioRxiv [Preprint]. 2024 May 19:2023.04.

    Insert

    HP1b (CBX1 Human)
    

    Use

    AAV and CRISPR

    Tags

    3xFLAG

    Expression

    Mammalian

    Mutation

    Encodes aa 111-173

    Promoter

    EF1a

    Available Since

    Aug. 22, 2024

    Availability

    Academic Institutions and Nonprofits only

    

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13. pBK1313-AAV-EFSNC-dSaCas9-MECP2(204-310)

    Plasmid

    #223158

    Purpose

    Expression of truncated MECP2 with dSaCas9 and empty gRNA scaffold

    Depositor

    Boris Kantor

    Article

    Kantor et al bioRxiv [Preprint]. 2024 May 19:2023.04.

    Insert

    MECP2 (MECP2 Human)
    

    Use

    AAV and CRISPR

    Tags

    3xFLAG

    Expression

    Mammalian

    Mutation

    Encodes aa 204-310

    Promoter

    EF1a

    Available Since

    Aug. 22, 2024

    Availability

    Academic Institutions and Nonprofits only

    

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14. pBK1307-AAV-EFSNC-dSaCas9-HP1b(79-173)

    Plasmid

    #223152

    Purpose

    Expression of truncated HP1b with dSaCas9 and empty gRNA scaffold

    Depositor

    Boris Kantor

    Article

    Kantor et al bioRxiv [Preprint]. 2024 May 19:2023.04.

    Insert

    HP1b (CBX1 Human)
    

    Use

    AAV and CRISPR

    Tags

    3xFLAG

    Expression

    Mammalian

    Mutation

    Encodes aa 79-173

    Promoter

    EF1a

    Available Since

    Aug. 22, 2024

    Availability

    Academic Institutions and Nonprofits only

    

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15. SpyTag-RBD Omicron BQ.1.1

    Plasmid

    #214725

    Purpose

    Expresses SARS-CoV-2 Omicron BQ.1.1 RBD (receptor-binding domain from Spike) with N-terminal SpyTag fusion in mammalian cells

    Depositor

    Mark Howarth

    Article

    Hills et al Nat Nanotechnol. 2024 May 6. doi: 10.103

    Insert

    Receptor-Binding Domain (S SARS-CoV-2)
    

    Tags

    SpyTag

    Expression

    Mammalian

    Promoter

    CMV

    Available Since

    June 17, 2024

    Availability

    Academic Institutions and Nonprofits only

    

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16. SpyTag-RBD Delta

    Plasmid

    #214723

    Purpose

    Expresses SARS-CoV-2 Delta RBD (receptor-binding domain from Spike) with N-terminal SpyTag fusion in mammalian cells

    Depositor

    Mark Howarth

    Article

    Hills et al Nat Nanotechnol. 2024 May 6. doi: 10.103

    Insert

    Receptor-Binding Domain (S SARS-CoV-2)
    

    Tags

    SpyTag

    Expression

    Mammalian

    Promoter

    CMV

    Available Since

    June 17, 2024

    Availability

    Academic Institutions and Nonprofits only

    

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17. pENTR223-CMV-Cre-U6-sgC0111-U6-sgRb1-U6-sgTrp53-U6-sgRbl2

    Plasmid

    #209062

    Purpose

    Entry vector that encodes sgRNAs against mouse Rb1, Trp53, Rbl2, and a non-targeting sgRNA (C0111) and CMV Cre recombinase.

    Depositor

    Matthew Oser

    Article

    Duplaquet et al Nat Cell Biol. 2023 Sep;25(9):1346-1358.

    Insert

    non-targeting sgRNA (C0111)
    

    Use

    Gateway vector to be used for lr reaction

    Promoter

    U6

    Available Since

    Dec. 20, 2023

    Availability

    Academic Institutions and Nonprofits only

    

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18. pMEXneo-TrkC-Δ6

    Plasmid

    #190204

    Purpose

    To express the human TrkC that has in the extracellular domain only the second IgG like domain. Still binds NT-3.

    Depositor

    Pantelis Tsoulfas

    Article

    Urfer et al J Biol Chem. 1998 Mar 6;273(10):5829-40.

    Insert

    TrkC (NTRK3 Human)
    

    Expression

    Mammalian

    Mutation

    The extracellualr domain conatins only the signal…

    Promoter

    Moloney mouse sarcoma virus right LTR

    Available Since

    Sept. 30, 2022

    Availability

    Academic Institutions and Nonprofits only

    

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19. Phage-PGK-Flag-HA-FKBP-T(G177D)

    Plasmid

    #181735

    Purpose

    for lentiviral expression of brachyury ORF in mammalian cells

    Depositor

    Charles Lin

    Article

    Sheppard et al Cell Rep Med. 2021 Jan 19;2(1):100188. d

    Insert

    T (brachyury)
    

    Use

    Lentiviral

    Mutation

    a silent mutation in the PAM site of an sgRNAt ta…

    Available Since

    March 21, 2022

    Availability

    Industry, Academic Institutions, and Nonprofits

    

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20. pENTR223-PARK7H126A

    Plasmid

    #115180

    Purpose

    Gateway cloning of PARK7H126A into any destination vector

    Depositor

    Mohan Babu

    Article

    Moutaoufik et al iScience. 2019 Sep 4;19:1114-1132. doi:

    Insert

    PARK7H126A (PARK7 Human)
    

    Use

    Gateway cloning into appropriate destination vect…

    Mutation

    p.H126A

    Available Since

    March 26, 2021

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

21. pENTR223-PARK7E163K

    Plasmid

    #115181

    Purpose

    Gateway cloning of PARK7E163K into any destination vector

    Depositor

    Mohan Babu

    Article

    Moutaoufik et al iScience. 2019 Sep 4;19:1114-1132. doi:

    Insert

    PARK7E163K (PARK7 Human)
    

    Use

    Gateway cloning into appropriate destination vect…

    Mutation

    p.E163K

    Available Since

    March 26, 2021

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

22. pENTR223-PARK7V51G

    Plasmid

    #115178

    Purpose

    Gateway cloning of PARK7V51G into any destination vector

    Depositor

    Mohan Babu

    Article

    Moutaoufik et al iScience. 2019 Sep 4;19:1114-1132. doi:

    Insert

    PARK7V51G (PARK7 Human)
    

    Use

    Gateway cloning into appropriate destination vect…

    Mutation

    p.V51G

    Available Since

    March 26, 2021

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

23. pENTR223-PARK7C53A

    Plasmid

    #115179

    Purpose

    Gateway cloning of PARK7C53G into any destination vector

    Depositor

    Mohan Babu

    Article

    Moutaoufik et al iScience. 2019 Sep 4;19:1114-1132. doi:

    Insert

    PARK7C53A (PARK7 Human)
    

    Use

    Gateway cloning into appropriate destination vect…

    Mutation

    p.C53A

    Available Since

    March 26, 2021

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

24. MSCV-HA-Nr4a1-Zf2

    Plasmid

    #160944

    Purpose

    Generation of retrovirus for the overexpression of Nr4a1 mutant (zinc finger 2 deletion)

    Depositor

    Matthew Steinhauser

    Article

    Zhang et al J Clin Invest. 2018 Nov 1;128(11):4898-4

    Insert

    Nr4a1 (Nr4a1 Mouse)
    

    Use

    Retroviral

    Tags

    HA tag

    Expression

    Mammalian

    Mutation

    Deletion of Zinc finger 2 (C306 to C330)

    Promoter

    MSCV-LTR

    Available Since

    Dec. 11, 2020

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

25. MSCV-HA-Nr4a1-Zf1

    Plasmid

    #160943

    Purpose

    Generation of retrovirus for the overexpression of Nr4a1 mutant (zinc finger 1 deletion)

    Depositor

    Matthew Steinhauser

    Article

    Zhang et al J Clin Invest. 2018 Nov 1;128(11):4898-4

    Insert

    Nr4a1 (Nr4a1 Mouse)
    

    Use

    Retroviral

    Tags

    HA tag

    Expression

    Mammalian

    Mutation

    Deletion of Zinc finger 1 (C270 to C290)

    Promoter

    MSCV-LTR

    Available Since

    Dec. 10, 2020

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

26. pTagGFP2-N SIN1 delta95-114

    Plasmid

    #124925

    Purpose

    For expression of a.a.95-114 deletion mutant of SIN1-GFP

    Depositor

    Jin Chen

    Article

    Hwang et al Cancer Res. 2019 Jul 1;79(13):3178-3184.

    Insert

    MAPKAP1 (MAPKAP1 Human)
    

    Tags

    TagGFP2

    Expression

    Mammalian

    Mutation

    Insert ORF was sirently mutated to be resistent t…

    Available Since

    May 20, 2019

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

27. pTagGFP2-N SIN1 delta116-127

    Plasmid

    #124926

    Purpose

    For expression of a.a.116-127 deletion mutant of SIN1-GFP

    Depositor

    Jin Chen

    Article

    Hwang et al Cancer Res. 2019 Jul 1;79(13):3178-3184.

    Insert

    MAPKAP1 (MAPKAP1 Human)
    

    Tags

    TagGFP2

    Expression

    Mammalian

    Mutation

    Insert ORF was sirently mutated to be resistent t…

    Available Since

    May 20, 2019

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

28. pKLV2-U6(gDmap1 v4)-PGK-Puro-BFP

    Plasmid

    #117143

    Purpose

    Express gRNA vs Dmap1

    Depositor

    Kosuke Yusa

    Article

    Yu et al Stem Cells. 2019 Apr 1. doi: 10.1002/ste

    Insert

    gDmap1 v4 (Dmap1 Synthetic)
    

    Use

    CRISPR and Lentiviral

    Mutation

    Deleted BbsI site within WPRE, modified BFP

    Promoter

    human U6 promoter, mouse PGK promoter

    Available Since

    April 26, 2019

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

29. pKLV2-U6(gDmap1 v5)-PGK-Puro-BFP

    Plasmid

    #117144

    Purpose

    Express gRNA vs Dmap1

    Depositor

    Kosuke Yusa

    Article

    Yu et al Stem Cells. 2019 Apr 1. doi: 10.1002/ste

    Insert

    gDmap1 v5 (Dmap1 Synthetic)
    

    Use

    CRISPR and Lentiviral

    Mutation

    Deleted BbsI site within WPRE, modified BFP

    Promoter

    human U6 promoter, mouse PGK promoter

    Available Since

    April 26, 2019

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

30. pKLV2-U6(gDmap1 v2)-PGK-Puro-BFP

    Plasmid

    #117141

    Purpose

    Express gRNA vs Dmap1

    Depositor

    Kosuke Yusa

    Article

    Yu et al Stem Cells. 2019 Apr 1. doi: 10.1002/ste

    Insert

    gDmap1 v2 (Dmap1 Synthetic)
    

    Use

    CRISPR and Lentiviral

    Mutation

    Deleted BbsI site within WPRE, modified BFP

    Promoter

    human U6 promoter, mouse PGK promoter

    Available Since

    April 26, 2019

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge