390 results

#141436

Knockout library targeting mouse SLC proteins.

Giulio Superti-Furga

May 18, 2020

Academic Institutions and Nonprofits only

#73178

Human sgRNA library in backbone lentiGuide-Puro targeting 19,114 genes and containing 76,441 unique sgRNAs along with 1000 non-targeting controls

John Doench, David Root

Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

Feb. 9, 2016

Academic Institutions and Nonprofits only

#1000000078

Genome-wide CRISPR gRNA pooled library for activation of human genes

Feng Zhang

June 27, 2016

Academic Institutions and Nonprofits only

#1000000111

Genome-wide CRISPR gRNA pooled library for activation of human genes

John Doench, David Root

Aug. 3, 2017

Academic Institutions and Nonprofits only

#1000000049

CRISPR gRNA knockout pooled library for targeting the human genome

Feng Zhang

May 8, 2014

Academic Institutions and Nonprofits only

#187246

Ultra-compact, human genome-wide CRISPRi library targeting each gene with a single element encoding a dual sgRNA cassette.

Marco Jost, Jonathan Weissman

Replogle et al eLife. 2022 Dec 28;11:e81856. doi: 10.75

Sept. 30, 2022

Academic Institutions and Nonprofits only

#73179

Human sgRNA library in backbone lentiCRISPRv2 targeting 19,114 genes and containing 76,441 unique sgRNAs along with 1000 non-targeting controls

John Doench, David Root

Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

Feb. 9, 2016

Academic Institutions and Nonprofits only

#85968

Barcode library for cloning gRNA sublibraries for single cell CRISPR analysis.

Jonathan Weissman

Adamson et al Cell. 2016 Dec 15;167(7):1867-1882.e21.

Feb. 14, 2017

Academic Institutions and Nonprofits only

#233697

Barcoding pooled library

Alejo Rodriguez-Fraticelli

Singh et al Cell Stem Cell. 2025 Feb 19:S1934-5909(2

March 6, 2025

Academic Institutions and Nonprofits only

#169942

Knockout library targeting ubiquitin ligases, deubiquitinases, and control genes.

Benjamin Ebert

Slabicki et al Nature. 2020 Sep;585(7824):293-297. doi:

Sept. 9, 2021

Academic Institutions and Nonprofits only

#1000000091

Genome-wide CRISPR gRNA pooled library for activation of human genes

Jonathan Weissman

Nov. 15, 2016

Academic Institutions and Nonprofits only

#73633

Mouse sgRNA library in backbone lentiGuide-Puro containing 78,637 unique sgRNAs targeting 19,674 genes along with 1000 non-targeting controls

John Doench, David Root

Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

Feb. 25, 2016

Academic Institutions and Nonprofits only

#1000000218

Feng Zhang

March 24, 2023

Academic Institutions and Nonprofits only

#83969

Version 2 of the human CRISPRi genome wide library

Jonathan Weissman

Horlbeck et al Elife. 2016 Sep 23;5. pii: e19760. doi:

Nov. 15, 2016

Academic Institutions and Nonprofits only

#110066

Targets 2,981 human metabolic genes with 29,790 guide RNAs. The library contains ~10 gRNAs per gene.

David Sabatini

Birsoy et al Cell. 2015 Jul 30;162(3):540-51. doi: 10

May 4, 2018

Academic Institutions and Nonprofits only

#162256

Knockout library that targets human epigenetic genes.

Kivanc Birsoy

Williams et al Cell Metab. 2020 Apr 7;31(4):852-861.e6.

Nov. 17, 2020

Academic Institutions and Nonprofits only

#162275

Knockout library targeting a set of human transcription factors for loss-of-function screening.

Chunliang Li

Zhang et al Elife. 2020 Oct 1;9. pii: 57858. doi: 10

Dec. 15, 2020

Academic Institutions and Nonprofits only

#247027

Human genome-wide CRISPR knockout library for the use of S. pyogenes Cas9. Each gene is targeted by 3 constructs.

John Doench, David Root

Drepanos et al bioRxiv 2025.08.26.672375; doi: https://

Oct. 2, 2025

Academic Institutions and Nonprofits only

#233215

Barcoding pooled library

Alejo Rodriguez-Fraticelli

Singh et al Cell Stem Cell. 2025 Feb 19:S1934-5909(2

March 6, 2025

Academic Institutions and Nonprofits only

#73632

Mouse sgRNA library in backbone lentiCRISPRv2 containing 78,637 unique sgRNAs targeting 19,674 genes along with 1000 non-targeting controls

John Doench, David Root

Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

Feb. 25, 2016

Academic Institutions and Nonprofits only

#113345

Activation library targeting the promoters of 6,213 genes that encode at least one putative membrane-associated protein isoform.

Gavin Wright

Chong et al Genome Biol. 2018 Nov 26;19(1):205. doi:

Jan. 4, 2019

Academic Institutions and Nonprofits only

#206045

The CellTag multi library of barcodes can be used to clonally label cells with DNA barcodes. These barcodes can be profiled directly with single-cell RNA and ATAC sequencing, to allow clonal tracking

Samantha Morris

Jindal et al Nat Biotechnol. 2023 Sep 25. doi: 10.103

Nov. 2, 2023

Academic Institutions and Nonprofits only

#122131

Increases transcriptional repression of genes encoding transcription factors in combination with dCas9 repression systems, such as the dCas9-KRAB system.

Stanley Qi

Liu et al Cell Stem Cell. 2018 Sep 28. pii: S1934-

April 25, 2019

Academic Institutions and Nonprofits only

#101929

Bassik lab Human CRISPR-Cas9 Deletion Library - Membrane proteins. Coexpresses mCherry.

Michael Bassik

Morgens et al Nat Commun. 2017 May 5;8:15178. doi: 10.

May 23, 2018

Academic Institutions and Nonprofits only

#101931

Bassik lab Human CRISPR-Cas9 Deletion Library - Trafficking, mitochondrial, motility. Coexpresses mCherry.

Michael Bassik

Morgens et al Nat Commun. 2017 May 5;8:15178. doi: 10.

May 23, 2018

Academic Institutions and Nonprofits only

#192821

Barcoded transcription factor ORF library for high throughput screening

Feng Zhang

Joung et al Cell. 2023 Jan 5;186(1):209-229.e26. doi

Jan. 11, 2023

Academic Institutions and Nonprofits only

#140961

Knockout library targeting human genes involved in cellular glycosylation.

Sriram Neelamegham

Zhu et al Glycobiology. 2020 Aug 8. pii: 5889976.

Sept. 9, 2020

Academic Institutions and Nonprofits only

#83985

Human CRISPRa Pooled Library targeting membrane proteins

Jonathan Weissman

Horlbeck et al Elife. 2016 Sep 23;5. pii: e19760. doi:

Jan. 12, 2017

Academic Institutions and Nonprofits only

#187081

Library targeting 2,989 mouse metabolic genes for activation of gene expression.

Kivanc Birsoy

Unlu et al Mol Cell. 2022 Aug 4;82(15):2832-2843.e7

Oct. 26, 2022

Academic Institutions and Nonprofits only

#131625

Bacterial inhibition library targeting every small RNA and ORF of the E. coli MG1655 genome. This library has higher inhibition efficiency than the psgRNA library.

David Bikard

Calvo-Villamanan et al Nucleic Acids Res. 2020 Apr 30. pii: 582

May 12, 2020

Academic Institutions and Nonprofits only

#1000000048

CRISPR gRNA knockout pooled library for targeting the human genome

Feng Zhang

May 8, 2014

Academic Institutions and Nonprofits only

#247026

Human genome-wide CRISPR knockout library for the use of S. pyogenes Cas9. Each gene is targeted by 3 constructs.

John Doench, David Root

Drepanos et al bioRxiv 2025.08.26.672375; doi: https://

Oct. 2, 2025

Academic Institutions and Nonprofits only

#90294

Optimized library offering improved accuracy, efficiency, and scalability for CRISPR screens compared to TKOv1

Jason Moffat

Hart et al G3 (Bethesda). 2017 Aug 7;7(8):2719-2727

May 5, 2017

Academic Institutions and Nonprofits only

#200011

Knockout library targeting a comprehensive set of mouse genes with annotated function as chromatin regulators.

Bradley Bernstein, Gabriel Griffin, Robert Manguso

Griffin et al Nature. 2021 Jul;595(7866):309-314. doi:

Dec. 15, 2023

Academic Institutions and Nonprofits only

#213694

Inducible barcoded library with 467 codon-optimized cDNAs with UMIs to test the impact of SLC transporters on biological processes.

RESOLUTE Consortium, Giulio Superti-Furga

Wolf et al Cell Chem Biol. 2024 Dec 24:S2451-9456(2

Aug. 30, 2024

Academic Institutions and Nonprofits only

#1000000052

CRISPR gRNA knockout pooled library for targeting the mouse genome

Feng Zhang

July 23, 2014

Academic Institutions and Nonprofits only

#83971

Human CRISPRi Pooled Library tartgeting kinsases, phosphatases and Drug Targets

Jonathan Weissman

Horlbeck et al Elife. 2016 Sep 23;5. pii: e19760. doi:

Dec. 14, 2016

Academic Institutions and Nonprofits only

#207471

CRISPR-based activation library with guide RNAs targeting all cell surface proteins.

Raj Chari

Yang et al Sci Adv. 2024 Feb 16;10(7):eadj2445. doi

Jan. 24, 2024

Academic Institutions and Nonprofits only

#200445

Knockout library targeting mouse cell surface genes.

Junjie Chen

Wang et al Proc Natl Acad Sci U S A. 2022 Jun 21;11

Oct. 26, 2023

Academic Institutions and Nonprofits only

#209552

The human, genome-wide, CRISPR knockout enAsCas12a gRNA library targets single genes and paralog pairs, triples, and quads with arrays of 4 gRNAs.

John Doench

Esmaeili Anvar et al Nat Commun. 2024 Apr 27;15(1):3577. doi:

Dec. 5, 2023

Academic Institutions and Nonprofits only