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Showing: 801 - 850 of 6475 results

  1. AAVS1-idCas9-vpr

    Plasmid
    #89985
    Purpose
    inducible CRISPR-ON system for controllable gene activation; this plasmid is used to insert dCas9-VPR casette in one allele of AAVS1 locus
    Depositor
    Jie Na
    Article
    Guo et al Protein Cell. 2017 Jan 23. doi: 10.1007/
    Insert
    dCas9-VPR
    Use
    Tags
    Expression
    Mammalian
    Mutation
    Promoter
    TRE-tight
    Available since
    June 6, 2017
    Availability
    Academic Institutions and Nonprofits only
    89985-plasmid-map-sequence-id-180638

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  9. pAAV.CAG.iGluSnFR3.v857.PDGFR

    Plasmid
    #178333
    Purpose
    Fluorescent reporter for glutamate, third generation, variant 857. iGluSnFR3.v857
    Depositor
    Kaspar Podgorski
    Article
    Aggarwal et al Nat Methods. 2023 May 4. doi: 10.1038/s4
    Insert
    pAAV CAG iGluSnFR3 v857.PDGFR
    Use
    AAV, Cre/Lox, Mouse Targeting, and Synthetic Biol…
    Tags
    IgK-chain, Myc epi tag, and PDGFR TM Domain
    Expression
    Mammalian
    Mutation
    Promoter
    Available since
    Feb. 3, 2022
    Availability
    Academic Institutions and Nonprofits only
    178333-plasmid-map-sequence-id-353666

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  11. pAAV-CamKII-Cre

    Plasmid
    #182736
    Purpose
    Cre expression under the control of CamKII promoter
    Depositor
    Janelia Viral Tools
    Insert
    Cre
    Use
    AAV
    Tags
    Expression
    Mutation
    Promoter
    CamKII
    Available since
    April 29, 2022
    Availability
    Academic Institutions and Nonprofits only
    182736-plasmid-map-sequence-id-360589

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  13. pEH_AAV_TERT_prom_-124C>T_C7C_1.8kb

    Plasmid
    #183080
    Purpose
    rAAV transfer plasmid with ITRs flanking: (1) TERT -124C>T promoter and exon 1 C7C (C21>T21), 1.8kb homologous recombination donor template with ~900 bp homology arms, and (2) PGK-Puro.
    Depositor
    Aviv Regev
    Article
    Hodis et al Science. 2022 Apr 29;376(6592):eabi8175.
    Insert
    TERT -124C>T promoter and exon 1 C7C (C21>T21), 1.8kb homologous recombination donor template with ~900 bp homology arms (TERT Human)
    Use
    AAV; Homologous recombination donor template
    Tags
    Expression
    Mutation
    -124C>T promoter, Exon 1 C7C (C21>T21) sile…
    Promoter
    None for primary insert (Though partial TERT prom…
    Available since
    June 9, 2022
    Availability
    Academic Institutions and Nonprofits only
    183080-plasmid-map-sequence-id-363419

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  17. pEH_AAV_TERT_prom_-146C>T_C7C_1.8kb

    Plasmid
    #183081
    Purpose
    rAAV transfer plasmid with ITRs flanking: (1) TERT -146C>T promoter and exon 1 C7C (C21>T21), 1.8kb homologous recombination donor template with ~900 bp homology arms, and (2) PGK-Puro.
    Depositor
    Aviv Regev
    Article
    Hodis et al Science. 2022 Apr 29;376(6592):eabi8175.
    Insert
    TERT -146C>T promoter and exon 1 C7C (C21>T21), 1.8kb homologous recombination donor template with ~900 bp homology arms (TERT Human)
    Use
    AAV; Homologous recombination donor template
    Tags
    Expression
    Mutation
    -146C>T promoter, Exon 1 C7C (C21>T21) sile…
    Promoter
    None for primary insert (Though partial TERT prom…
    Available since
    June 9, 2022
    Availability
    Academic Institutions and Nonprofits only
    183081-plasmid-map-sequence-id-363415

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  29. pAAV-EF1a-iCreV

    Plasmid
    #140135
    Purpose
    Can be used to generate AAV virus that will express light-inducible site-specific iCreV recombinase
    Depositor
    Hongkui Zeng
    Article
    Yao et al Nat Methods. 2020 Mar 23. pii: 10.1038/s
    Has Service
    AAV PHP.eB and AAV1
    Insert
    iCreV
    Use
    AAV and Cre/Lox
    Tags
    Expression
    Mammalian
    Mutation
    Promoter
    EF1alpha
    Available since
    April 23, 2020
    Availability
    Academic Institutions and Nonprofits only
    140135-plasmid-map-sequence-id-292208

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  32. pAAV-MCU-EGFP

    Plasmid
    #181866
    Purpose
    Expresses GFP-tagged mitochondrial calcium uniporter (MCU) under control of the CaMKIIa promoter
    Depositor
    Hilmar Bading
    Article
    Qiu et al Nat Commun. 2013;4:2034. doi: 10.1038/nc
    Insert
    mitochondrial calcium uniporter (Mcu Mouse)
    Use
    AAV and Adenoviral
    Tags
    EGFP
    Expression
    Mammalian
    Mutation
    Promoter
    CaMKIIa
    Available since
    March 17, 2022
    Availability
    Academic Institutions and Nonprofits only
    181866-plasmid-map-sequence-id-355942

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  34. pUCmini-iCAP-AAV9.452sub.LUNG1

    Plasmid
    #184592
    Purpose
    non-standard AAV2 rep-AAV9.452sub.LUNG1 cap plasmid with AAV cap expression controlled by a tTA-TRE amplification system for mouse lung transduction after intravenous injection
    Depositor
    Viviana Gradinaru
    Article
    Goertsen et al Mol Ther Methods Clin Dev. 2022 Aug 1;26
    Insert
    Synthetic construct isolate AAV9.452sub.LUNG1 VP1 gene
    Use
    AAV
    Tags
    Expression
    Mammalian
    Mutation
    7 amino acid substitution between VP1 452 and VP1…
    Promoter
    p41
    Available since
    July 14, 2022
    Availability
    Academic Institutions and Nonprofits only
    184592-plasmid-map-sequence-id-364433

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  35. pAAV-CaMKII-GFP

    Plasmid
    #64545
    Purpose
    AAV-mediated expression of GFP under the CaMKII promoter.
    Depositor
    Edward Boyden
    Insert
    GFP
    Use
    AAV
    Tags
    Expression
    Mammalian
    Mutation
    Promoter
    CaMKII
    Available since
    Nov. 19, 2015
    Availability
    Academic Institutions and Nonprofits only
    64545-plasmid-map-sequence-id-130468

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  39. AAV-Syn-NS1

    Plasmid
    #175276
    Purpose
    AAV vector mediating bicistronic expression of NS1 gene of YFV-17D and dTomato with NLS
    Depositor
    Wei Xu
    Article
    Li et al Nat Methods. 2021 Nov 25. pii: 10.1038/s
    Insert
    Nonstructural protein 1 (NS1) of YFV-17D; NLS-dTomato (POLY Yellow fever virus strain 17D)
    Use
    AAV
    Tags
    NLS-dTomato (P2A cleavage)
    Expression
    Mutation
    Promoter
    Synapsin
    Available since
    Nov. 30, 2021
    Availability
    Academic Institutions and Nonprofits only
    175276-plasmid-map-sequence-id-349086

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  44. pAAV CTG 700x

    Plasmid
    #63087
    Purpose
    AdenoAssociated Virus plasmid containing expanded repeats--CTG 700x that is the mutation found in Myotonic Dystrophic type 1
    Depositor
    Nicolas Charlet-Berguerand
    Insert
    CTG REPEATS
    Use
    AAV
    Tags
    EGFP
    Expression
    Mammalian
    Mutation
    CTG 700x that is the mutation found in Myotonic D…
    Promoter
    CMV
    Available since
    April 21, 2015
    Availability
    Academic Institutions and Nonprofits only
    63087-plasmid-map-sequence-id-275393

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  46. pAAV-MP-84-spCas9-U6-gRNA

    Plasmid
    #206935
    Purpose
    Expression of spCas9 endonuclease and gRNA in an AAV vector allowing packaging of viral genome smaller than 5 kb.
    Depositor
    Markus Grompe
    Insert
    spCas9
    Use
    AAV
    Tags
    SV40 NLS
    Expression
    Mammalian
    Mutation
    Promoter
    MP-84
    Available since
    Sept. 14, 2023
    Availability
    Academic Institutions and Nonprofits only
    206935-plasmid-map-sequence-id-407781

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  48. AICSDP-35:AAVS1-mEGFP

    Plasmid
    #91565
    Purpose
    Homology arms and linker-mEGFP sequence for internal insertion of CAGGS-mEGFP at the AAVS1 safe harbor location in human cells as a reporter for cytoplasmic mEGFP
    Depositor
    Allen Institute for Cell Science
    Insert
    AAVS1 Homology Arms with CAGGS driven mEGFP (AAVS1 Human)
    Use
    CRISPR; Donor template
    Tags
    Expression
    Mammalian
    Mutation
    Promoter
    CAG
    Available since
    June 7, 2017
    Availability
    Industry, Academic Institutions, and Nonprofits
    91565-plasmid-map-sequence-id-456463

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  49. pAAV-hSyn-GRAB_OTmut

    Plasmid
    #185388
    Purpose
    Expresses the genetically-encoded fluorescent oxytocin(OT) control sensor GRAB_OTmut in neurons
    Depositor
    Yulong Li
    Article
    Qian et al Nat Biotechnol. 2023 Jan 2. doi: 10.1038
    Has Service
    AAV1 and AAV9
    Insert
    GPCR activation based oxytocin control sensor GRAB_OTmut
    Use
    AAV
    Tags
    Expression
    Mutation
    Promoter
    hSyn
    Available since
    Sept. 20, 2022
    Availability
    Academic Institutions and Nonprofits only
    185388-plasmid-map-sequence-id-372581

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  50. pAAV-AcGFP-progerin

    Plasmid
    #86947
    Purpose
    Construct used to synthesize progerin mRNA. Please note the plasmid contains LMNA gene with nucleotide C1824T mutation.
    Depositor
    Alex Hewitt
    Insert
    AcGFP-progerin (LMNA Human)
    Use
    AAV
    Tags
    AcGFP
    Expression
    Mammalian
    Mutation
    progerin sequence is LMNA gene with nucleotide C1…
    Promoter
    CMV and T7
    Available since
    June 7, 2017
    Availability
    Academic Institutions and Nonprofits only
    86947-plasmid-map-sequence-id-180625

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Showing: 801 - 850 of 6475 results