We narrowed to 15,557 results for: LEA

1. pcDNA3.1-GSDMD_H270A

   Plasmid

   #224701

   Purpose

   Expression of mutated Gasdermin D_H270A (GSDMD_H270A) in transfected mammalian cell lines

   Depositor

   Christopher Overall

   Article

   Grin et al Cell Rep. 2024 Dec 24;43(12):115080. doi

   Insert

   GSDMD_H270A (GSDMD Human)
   

   Use

   Tags

   FLAG

   Expression

   Mammalian

   Mutation

   H270A

   Promoter

   CMV

   Available since

   July 2, 2025

   Availability

   Industry, Academic Institutions, and Nonprofits

   

   Enlarge

2. pcDNA3.1-GSDMD_Q29A

   Plasmid

   #224702

   Purpose

   Expression of mutated Gasdermin D_Q29A (GSDMD_Q29A) in transfected mammalian cell lines

   Depositor

   Christopher Overall

   Article

   Grin et al Cell Rep. 2024 Dec 24;43(12):115080. doi

   Insert

   GSDMD_Q29A (GSDMD Human)
   

   Use

   Tags

   FLAG

   Expression

   Mammalian

   Mutation

   Q29A

   Promoter

   CMV

   Available since

   July 2, 2025

   Availability

   Industry, Academic Institutions, and Nonprofits

   

   Enlarge

3. pcDNA3.1-GSDMD_Q29A_H270A

   Plasmid

   #224703

   Purpose

   Expression of mutant Gasdermin D_Q29A_H270A (GSDMD_Q29A_H270A) in transfected mammalian cell lines

   Depositor

   Christopher Overall

   Article

   Grin et al Cell Rep. 2024 Dec 24;43(12):115080. doi

   Insert

   GSDMD_Q29A_H270A (GSDMD Human)
   

   Use

   Tags

   FLAG

   Expression

   Mammalian

   Mutation

   Q29A and H270A

   Promoter

   CMV

   Available since

   July 2, 2025

   Availability

   Industry, Academic Institutions, and Nonprofits

   

   Enlarge

4. pcDNA3.1-GSDMD_D275A

   Plasmid

   #224704

   Purpose

   Expression of mutated Gasdermin D_D275A (GSDMD_D275A) in transfected mammalian cell lines

   Depositor

   Christopher Overall

   Article

   Grin et al Cell Rep. 2024 Dec 24;43(12):115080. doi

   Insert

   GSDMD_D275A (GSDMD Human)
   

   Use

   Tags

   FLAG

   Expression

   Mammalian

   Mutation

   D275A

   Promoter

   CVM

   Available since

   July 2, 2025

   Availability

   Industry, Academic Institutions, and Nonprofits

   

   Enlarge

5. pcDNA3.1-GSDMD_H270A_D275A

   Plasmid

   #224705

   Purpose

   Expression of mutated Gasdermin D_H270A_D275A (GSDMD_D275A) in transfected mammalian cell lines

   Depositor

   Christopher Overall

   Article

   Grin et al Cell Rep. 2024 Dec 24;43(12):115080. doi

   Insert

   GSDMD_Q29A_H270A (GSDMD Human)
   

   Use

   Tags

   FLAG

   Expression

   Mammalian

   Mutation

   H270A and D275A

   Promoter

   CMV

   Available since

   July 2, 2025

   Availability

   Industry, Academic Institutions, and Nonprofits

   

   Enlarge

6. pCAG-MCP-Lbr-V5-mCherry

   Plasmid

   #235093

   Purpose

   Lbr mCherry fusion protein with MCP domain

   Depositor

   Mitchell Guttman

   Article

   Bhat et al Nature. 2024 May;629(8014):1165-1173. do

   Insert

   pCAG-MCP-Lbr-V5-mCherry (LBR Human)
   

   Use

   Tags

   Expression

   Mammalian

   Mutation

   Promoter

   CAG

   Available since

   May 7, 2025

   Availability

   Academic Institutions and Nonprofits only

   

   Enlarge

7. pBIG1e-CDK12deltaNTD /Cyclin K

   Plasmid

   #231741

   Purpose

   Protein expression in insect cells

   Depositor

   Jesper Svejstrup

   Article

   Lopez Martinez et al Mol Cell. 2025 May 15;85(10):1952-1967.e

   Inserts

   CDK12 (CDK12 Human)
   CCNK (CCNK Human)
   

   Use

   Tags

   Flag-3C

   Expression

   Insect

   Mutation

   CDK12(700-1490)

   Promoter

   Available since

   May 2, 2025

   Availability

   Academic Institutions and Nonprofits only

   

   Enlarge

8. pBIG1e-CDK12deltaCTD/Cyclin K

   Plasmid

   #231742

   Purpose

   Protein expression in insect cells

   Depositor

   Jesper Svejstrup

   Article

   Lopez Martinez et al Mol Cell. 2025 May 15;85(10):1952-1967.e

   Inserts

   CDK12 (CDK12 Human)
   CCNK (CCNK Human)
   

   Use

   Tags

   Flag-3C

   Expression

   Insect

   Mutation

   CDK12(1-1082)

   Promoter

   Available since

   May 2, 2025

   Availability

   Academic Institutions and Nonprofits only

   

   Enlarge

9. pBIG1e-CDK12-KiD/Cyclin K

   Plasmid

   #231743

   Purpose

   Protein expression in insect cells

   Depositor

   Jesper Svejstrup

   Article

   Lopez Martinez et al Mol Cell. 2025 May 15;85(10):1952-1967.e

   Inserts

   CDK12 (CDK12 Human)
   CCNK (CCNK Human)
   

   Use

   Tags

   Flag-3C

   Expression

   Insect

   Mutation

   CDK12(700-1082)

   Promoter

   Available since

   May 2, 2025

   Availability

   Academic Institutions and Nonprofits only

   

   Enlarge

10. pBIG1e-CDK12deltaRS/Cyclin K

    Plasmid

    #231744

    Purpose

    Protein expression in insect cells

    Depositor

    Jesper Svejstrup

    Article

    Lopez Martinez et al Mol Cell. 2025 May 15;85(10):1952-1967.e

    Inserts

    CDK12 (CDK12 Human)
    CCNK (CCNK Human)
    

    Use

    Tags

    Flag-3C

    Expression

    Insect

    Mutation

    CDK12(delta104-380)

    Promoter

    Available since

    May 2, 2025

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

11. pCAG-SpCas9-P2A-EGFP (MSP2582)

    Plasmid

    #223067

    Purpose

    pCAG human codon optimized wild-type SpCas9 expression plasmid with C-terminal NLS(SV40)-3xFLAG-P2A-EGFP

    Depositor

    Benjamin Kleinstiver

    Article

    Silverstein et al Nature. 2025 Apr 22. doi: 10.1038/s41586

    Insert

    human codon optimized SpCas9-P2A-EGFP
    

    Use

    CRISPR

    Tags

    NLS(SV40)-3xFLAG-P2A-EGFP

    Expression

    Mammalian

    Mutation

    Promoter

    CAG

    Available since

    April 23, 2025

    Availability

    Academic Institutions and Nonprofits only

    

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12. pLenti-multi-CRISPR-sgRipk1_#1-puro

    Plasmid

    #231984

    Purpose

    Knockout mouse Ripk1

    Depositor

    Brian Ruffell

    Article

    Hanggi et al Cancer Cell. 2024 Nov 13:S1535-6108(24)0

    Insert

    sgRNA with Cas9 with puromycin resistance (Ripk1 Mouse)
    

    Use

    CRISPR and Lentiviral

    Tags

    Expression

    Mutation

    Promoter

    Available since

    Feb. 19, 2025

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

13. pLenti-multi-CRISPR-sgRipk1_#2-puro

    Plasmid

    #231983

    Purpose

    Knockout mouse Ripk1

    Depositor

    Brian Ruffell

    Article

    Hanggi et al Cancer Cell. 2024 Nov 13:S1535-6108(24)0

    Insert

    sgRNA with Cas9 with puromycin resistance (Ripk1 Mouse)
    

    Use

    CRISPR and Lentiviral

    Tags

    Expression

    Mutation

    Promoter

    Available since

    Feb. 19, 2025

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

14. 3xFLAG-DGKδ2-ΔSAMD

    Plasmid

    #226507

    Purpose

    Express N-terminal three tandem FLAG epitope tags, followed by an enterokinase cleavage site and human DGKD gene deleted SAM domain

    Depositor

    Fumio Sakane, Chiaki Murakami

    Article

    Murakami et al J Biol Chem. 2020 Mar 6;295(10):2932-294

    Insert

    DGKD (DGKD Human)
    

    Use

    Tags

    Three tandem FLAG epitope tag and enterokinase cl…

    Expression

    Mammalian

    Mutation

    deleted sterile alpha motif domain (deleted amino…

    Promoter

    CMV

    Available since

    Jan. 6, 2025

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

15. pcDNA3.1-FRB:GSlinker:SSD

    Plasmid

    #228535

    Purpose

    FRB protein in fusion with a bipartite SSD degron, consisting of fragments of human Skp1 and SOCS2 proteins, through a flexible glycine-serine linker.

    Depositor

    Roman Jerala

    Article

    Verbic et al ACS Synth Biol. 2024 Mar 15;13(3):792-80

    Insert

    FRB:GSlinker:SSD (SKP1, SOCS2 Synthetic, Human)
    

    Use

    Tags

    Expression

    Mammalian

    Mutation

    Promoter

    CMV

    Available since

    Jan. 3, 2025

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

16. pAAV-hSyn-DIO-FLAG-hM4D(Gi)-P2A-ArgiNLS-AausFP1

    Plasmid

    #220609

    Purpose

    Neuron-specific, Cre-dependent co-expression of FLAG-tagged inhibitory hM4D(Gi) DREADD receptor, and a single-cell discriminating version of AausFP1 as a reporter.

    Depositor

    Sam Golden

    Article

    Szelenyi et al Proc Natl Acad Sci U S A. 2024 Aug 6;121

    Insert

    FLAG-hM4D(Gi)-P2A-ArgiNLS-AausFP1
    

    Use

    AAV and Cre/Lox

    Tags

    FLAG; ArgiNLS

    Expression

    Mammalian

    Mutation

    Promoter

    hSyn

    Available since

    Dec. 11, 2024

    Availability

    Academic Institutions and Nonprofits only

    

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17. Cdk13_intron3_sg4_pX458

    Plasmid

    #127339

    Purpose

    sgRNA that cuts within intron 3 of mouse CDK13 genomic locus- guide #4

    Depositor

    Phil Sharp

    Article

    Insco et al Science. 2023 Apr 21;380(6642):eabn7625.

    Insert

    Mouse Cdk13 Intron 3 sgRNA (Cdk13 Mouse)
    

    Use

    CRISPR and Mouse Targeting

    Tags

    Expression

    Mutation

    Promoter

    U6 Promoter

    Available since

    Dec. 11, 2024

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

18. Cdk13_intron4_sg3_pX330

    Plasmid

    #127340

    Purpose

    sgRNA that cuts within intron 4 of mouse CDK13 genomic locus- guide #3

    Depositor

    Phil Sharp

    Article

    Insco et al Science. 2023 Apr 21;380(6642):eabn7625.

    Insert

    Mouse Cdk13 Intron 4 Targeting sgRNA (Cdk13 Mouse)
    

    Use

    CRISPR and Mouse Targeting

    Tags

    Expression

    Mutation

    Promoter

    U6 Promoter

    Available since

    Dec. 11, 2024

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

19. pCR8/GW_TOPO_Cdk13_Untagged

    Plasmid

    #127342

    Purpose

    Untagged mouse Cdk13 transgene (NP_001074527.1 isoform) cloned into Gateway entry vector

    Depositor

    Phil Sharp

    Article

    Insco et al Science. 2023 Apr 21;380(6642):eabn7625.

    Insert

    Cyclin Dependent Kinase 13 (Cdk13 Mouse)
    

    Use

    Entry vector with transgene for gateway cloning

    Tags

    Expression

    Mutation

    Base pairs 1-1554 of transgene are codon optimize…

    Promoter

    None

    Available since

    Dec. 11, 2024

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

20. pAAV-U6-sgRev-erba-hSyn-mCherry-KASH

    Plasmid

    #223226

    Purpose

    guideRNA targeting the mouse Rev-erb alpha (Nr1d1)

    Depositor

    Kyungjin Kim

    Article

    Park et al Commun Biol. 2024 Aug 15;7(1):998. doi:

    Insert

    Nr1d1 (Nr1d1 Mouse)
    

    Use

    AAV, CRISPR, and Mouse Targeting

    Tags

    mCherry

    Expression

    Mammalian

    Mutation

    Promoter

    U6

    Available since

    Sept. 11, 2024

    Availability

    Academic Institutions and Nonprofits only

    

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