3x NFAT binding sequence upstream of a luciferase reporter; can be used to assay signal transduction through Ca2+, calcineurin and NFAT in any tissue

Conventional dCas9 repressor-dCas9-KRAB

Construct for labelling actin filaments in mammalian cells with lifeact-mScarlet3

3rd gen lentiviral Luciferase expression vector, CMV promoter, Puro

Entry vector to clone sgRNA(s) into the CROPseq-multi construct with Puromycin resistance

Expresses ZIM3 KRAB domain fused to PYL1

Expresses VP64-dCas9-VP64 and MS2-p65-HSF1 fusion proteins

Express CD19

Ready-to-use AAV Retrograde particles produced from pAAV-hSyn-hChR2(H134R)-EYFP (#26973). In addition to the viral particles, you will also receive purified pAAV-hSyn-hChR2(H134R)-EYFP plasmid DNA. hSyn-driven, humanized channelrhodopsin H134R mutant fused to EYFP for optogenetic activation. These AAV were produced with a retrograde serotype, which permits retrograde access to projection neurons. These AAV preparations are suitable purity for injection into animals.

mitochondria targeted dsRED expressed off of EF1a promoter

Fluorescent reporter for DNA damage

Green fluorescent indicator for calcium imaging in the endoplasmic reticulum

Contains 58,071 gRNAs targeting 6,213 membrane proteins and 500 non-targeting gRNAs

Dual expression vector for bacteria and mammalian cells producing mScarlet3 red fluorescent protein

constitutive, ectopic expression of a helicase-dead mutant of human WRN (K577M)

constitutive, ectopic expression of an exonuclease-dead mutant of human WRN (E84A)

Expression of lyso-pHluorin in mammalian cells for optical readout of lysosomal acidification

Ready-to-use AAV5 particles produced from pAAV-Syn-ChrimsonR-tdT (#59171). In addition to the viral particles, you will also receive purified pAAV-Syn-ChrimsonR-tdT plasmid DNA. Syn-driven ChrimsonR-tdTomato expression for optogenetic neural activation. These AAV preparations are suitable purity for injection into animals.

constitutive, ectopic expression of an endonuclease/helicase-dead mutant of human WRN

Mammalian expression 8xHis-Ub