We narrowed to 31,327 results for: uros

1. pHW539

   Plasmid

   #198811

   Purpose

   Dominant negative form of Protein Kinase A (PKA). Lowers PKA activity in targeted neurons.

   Depositor

   Paul Sternberg

   Article

   Nava et al Proc Natl Acad Sci U S A. 2023 Dec 19;12

   Insert

   15xUAS::PKA(DN)-SL2-GFP::let-858 3'UTR
   

   Expression

   Worm

   Mutation

   G310D mutation to abolish the binding of cAMP of …

   Available Since

   April 28, 2023

   Availability

   Academic Institutions and Nonprofits only

   

   Enlarge

2. pCMV(MinDis)-iEscSnFR_PM

   Plasmid

   #182813

   Purpose

   Develop a family of genetically encoded fluorescent biosensors for nicotinic agonists, termed iDrugSnFRs, thus enabling optical subcellular pharmacokinetics for nicotinic agonists

   Depositor

   Henry Lester

   Article

   Nichols et al J Neurosci. 2023 Mar 2:JN-RM-1519-22. do

   Insert

   iEscSnFR_PM
   

   Expression

   Mammalian

   Promoter

   hCMV

   Available Since

   Jan. 18, 2023

   Availability

   Academic Institutions and Nonprofits only

   

   Enlarge

3. pCMV(MinDis)-iEscSnFR_cyto

   Plasmid

   #182814

   Purpose

   Develop a family of genetically encoded fluorescent biosensors for nicotinic agonists, termed iDrugSnFRs, thus enabling optical subcellular pharmacokinetics for nicotinic agonists

   Depositor

   Henry Lester

   Article

   Nichols et al J Neurosci. 2023 Mar 2:JN-RM-1519-22. do

   Insert

   iEscSnFR_cyto
   

   Expression

   Mammalian

   Promoter

   hCMV

   Available Since

   Jan. 18, 2023

   Availability

   Academic Institutions and Nonprofits only

   

   Enlarge

4. pCMV(MinDis)-iFluoxSnFR_ER

   Plasmid

   #182815

   Purpose

   Develop a family of genetically encoded fluorescent biosensors for nicotinic agonists, termed iDrugSnFRs, thus enabling optical subcellular pharmacokinetics for nicotinic agonists

   Depositor

   Henry Lester

   Article

   Nichols et al J Neurosci. 2023 Mar 2:JN-RM-1519-22. do

   Insert

   iFluoxSnFR_ER
   

   Expression

   Mammalian

   Promoter

   hCMV

   Available Since

   Jan. 18, 2023

   Availability

   Academic Institutions and Nonprofits only

   

   Enlarge

5. pCMV(MinDis)-iFluoxSnFR_PM

   Plasmid

   #182816

   Purpose

   Develop a family of genetically encoded fluorescent biosensors for nicotinic agonists, termed iDrugSnFRs, thus enabling optical subcellular pharmacokinetics for nicotinic agonists

   Depositor

   Henry Lester

   Article

   Nichols et al J Neurosci. 2023 Mar 2:JN-RM-1519-22. do

   Insert

   iFluoxSnFR_PM
   

   Expression

   Mammalian

   Promoter

   hCMV

   Available Since

   Jan. 18, 2023

   Availability

   Academic Institutions and Nonprofits only

   

   Enlarge

6. pCMV(MinDis)-iFluoxSnFR_cyto

   Plasmid

   #182817

   Purpose

   Develop a family of genetically encoded fluorescent biosensors for nicotinic agonists, termed iDrugSnFRs, thus enabling optical subcellular pharmacokinetics for nicotinic agonists

   Depositor

   Henry Lester

   Article

   Nichols et al J Neurosci. 2023 Mar 2:JN-RM-1519-22. do

   Insert

   iFluoxSnFR_cyto
   

   Expression

   Mammalian

   Promoter

   hCMV

   Available Since

   Jan. 18, 2023

   Availability

   Academic Institutions and Nonprofits only

   

   Enlarge

7. pAAV9-hSyn-iEscSnFR_ER

   Plasmid

   #182818

   Purpose

   Develop a family of genetically encoded fluorescent biosensors for nicotinic agonists, termed iDrugSnFRs, thus enabling optical subcellular pharmacokinetics for nicotinic agonists

   Depositor

   Henry Lester

   Article

   Nichols et al J Neurosci. 2023 Mar 2:JN-RM-1519-22. do

   Insert

   iEscSnFR_ER
   

   Use

   AAV

   Promoter

   hSyn

   Available Since

   Jan. 18, 2023

   Availability

   Academic Institutions and Nonprofits only

   

   Enlarge

8. pAAV9-hSyn-iEscSnFR_PM

   Plasmid

   #182819

   Purpose

   Develop a family of genetically encoded fluorescent biosensors for nicotinic agonists, termed iDrugSnFRs, thus enabling optical subcellular pharmacokinetics for nicotinic agonists

   Depositor

   Henry Lester

   Article

   Nichols et al J Neurosci. 2023 Mar 2:JN-RM-1519-22. do

   Insert

   iEscSnFR_PM
   

   Use

   AAV

   Promoter

   hSyn

   Available Since

   Jan. 18, 2023

   Availability

   Academic Institutions and Nonprofits only

   

   Enlarge

9. pAAV9-hSyn-iEscSnFR_cyto

   Plasmid

   #182820

   Purpose

   Develop a family of genetically encoded fluorescent biosensors for nicotinic agonists, termed iDrugSnFRs, thus enabling optical subcellular pharmacokinetics for nicotinic agonists

   Depositor

   Henry Lester

   Article

   Nichols et al J Neurosci. 2023 Mar 2:JN-RM-1519-22. do

   Insert

   iEscSnFR_cyto
   

   Use

   AAV

   Promoter

   hSyn

   Available Since

   Jan. 18, 2023

   Availability

   Academic Institutions and Nonprofits only

   

   Enlarge

10. pAAV9-hSyn-iFluoxSnFR_ER

    Plasmid

    #182821

    Purpose

    Develop a family of genetically encoded fluorescent biosensors for nicotinic agonists, termed iDrugSnFRs, thus enabling optical subcellular pharmacokinetics for nicotinic agonists

    Depositor

    Henry Lester

    Article

    Nichols et al J Neurosci. 2023 Mar 2:JN-RM-1519-22. do

    Insert

    iFluoxSnFR_ER
    

    Use

    AAV

    Promoter

    hSyn

    Available Since

    Jan. 18, 2023

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

11. pAAV9-hSyn-iFluoxSnFR_PM

    Plasmid

    #182822

    Purpose

    Develop a family of genetically encoded fluorescent biosensors for nicotinic agonists, termed iDrugSnFRs, thus enabling optical subcellular pharmacokinetics for nicotinic agonists

    Depositor

    Henry Lester

    Article

    Nichols et al J Neurosci. 2023 Mar 2:JN-RM-1519-22. do

    Insert

    iFluoxSnFR_PM
    

    Use

    AAV

    Promoter

    hSyn

    Available Since

    Jan. 18, 2023

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

12. pAAV9-hSyn-iFluoxSnFR_cyto

    Plasmid

    #182823

    Purpose

    Develop a family of genetically encoded fluorescent biosensors for nicotinic agonists, termed iDrugSnFRs, thus enabling optical subcellular pharmacokinetics for nicotinic agonists

    Depositor

    Henry Lester

    Article

    Nichols et al J Neurosci. 2023 Mar 2:JN-RM-1519-22. do

    Insert

    iFluoxSnFR_cyto
    

    Use

    AAV

    Promoter

    hSyn

    Available Since

    Jan. 18, 2023

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

13. pCMV(MinDis)-iEscSnFR_ER

    Plasmid

    #182812

    Purpose

    Develop a family of genetically encoded fluorescent biosensors for nicotinic agonists, termed iDrugSnFRs, thus enabling optical subcellular pharmacokinetics for nicotinic agonists

    Depositor

    Henry Lester

    Article

    Nichols et al J Neurosci. 2023 Mar 2:JN-RM-1519-22. do

    Insert

    iEscSnFR_ER
    

    Expression

    Mammalian

    Promoter

    hCMV

    Available Since

    Jan. 18, 2023

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

14. W118-1_eGFP

    Plasmid

    #180379

    Purpose

    lentiviral transduction of eGFP gene

    Depositor

    Huda Zoghbi

    Article

    Lee et al EMBO J. 2021 Apr 1;40(7):e106106. doi: 1

    Insert

    eGFP (eGFP )
    

    Use

    Lentiviral

    Expression

    Mammalian

    Promoter

    CMV

    Available Since

    Dec. 1, 2022

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

15. pHA853 - mec-4p::Fynempty

    Plasmid

    #139210

    Purpose

    Control vector for Fyn kinase expression in mec-4 neurons

    Depositor

    Anne Hart

    Article

    Ryan et al EMBO J. 2021 Feb 1;40(3):e105001. doi: 1

    Insert

    Fyn (FYN Human)
    

    Expression

    Worm

    Mutation

    deletion and frame shift to prevent Fyn expression

    Available Since

    Dec. 7, 2020

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

16. pHA850 - osm-10p::FynY531F

    Plasmid

    #139207

    Purpose

    Express activated Fyn kinase in osm-10 neurons

    Depositor

    Anne Hart

    Article

    Ryan et al EMBO J. 2021 Feb 1;40(3):e105001. doi: 1

    Insert

    Fyn (FYN Human)
    

    Expression

    Worm

    Mutation

    Y531F

    Available Since

    Dec. 7, 2020

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

17. pHA851 - osm-10p::Fynempty

    Plasmid

    #139208

    Purpose

    Control vector for Fyn kinase expression in osm-10 neurons

    Depositor

    Anne Hart

    Article

    Ryan et al EMBO J. 2021 Feb 1;40(3):e105001. doi: 1

    Insert

    Fyn (FYN Human)
    

    Expression

    Worm

    Mutation

    deletion and frame shift to prevent Fyn expression

    Available Since

    Dec. 7, 2020

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

18. FUS_LC_withR

    Plasmid

    #139128

    Purpose

    express FUS LC with the same number and spacing of arginines as hnRNPA2 LC

    Depositor

    Nicolas Fawzi

    Article

    Ryan et al EMBO J. 2021 Feb 1;40(3):e105001. doi: 1

    Insert

    FUS (FUS Human)
    

    Expression

    Bacterial

    Mutation

    add arginines

    Available Since

    Dec. 7, 2020

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

19. hnRNPA2_LC_nocharge_wR

    Plasmid

    #139119

    Purpose

    express hnRNPA2 LC with no charged residues with R added back

    Depositor

    Nicolas Fawzi

    Article

    Ryan et al EMBO J. 2021 Feb 1;40(3):e105001. doi: 1

    Insert

    hnRNPA2 (HNRNPA2B1 Human)
    

    Expression

    Bacterial

    Mutation

    remove all K, most D

    Available Since

    Dec. 7, 2020

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

20. FUS_LC_charge

    Plasmid

    #139126

    Purpose

    express FUS LC with an hnRNPA2 LC-like charge patterning

    Depositor

    Nicolas Fawzi

    Article

    Ryan et al EMBO J. 2021 Feb 1;40(3):e105001. doi: 1

    Insert

    FUS (FUS Human)
    

    Expression

    Bacterial

    Mutation

    Add R, K, D to make FUS LC have similar charge pa…

    Available Since

    Dec. 7, 2020

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

21. Ir7a-T2A-QF2 HDR plasmid

    Plasmid

    #140943

    Purpose

    Plasmid for CRISPR-generated knock-in line that expresses a QF2 transcriptional activator by knocking-in a T2A-QF2 fragment into the coding sequence of the endogenous Aedes aegypti Ir7a gene

    Depositor

    Leslie Vosshall

    Article

    Jove et al Neuron. 2020 Dec 23;108(6):1163-1180.e12

    Insert

    Ir7a-left-HDR-arm; T2A-QF2-SV40; 3xP3-dsRed-SV40; Ir7a-right-HDR-arm
    

    Available Since

    Oct. 16, 2020

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

22. pLenti-CMV-TIRAP-cGASΔN-HA

    Plasmid

    #130921

    Purpose

    Expresses human cGASΔN (aa160-522)-HA with an N terminal fusion of the TIRAP N terminus (aa1-85); Puromycin selection marker

    Depositor

    Jonathan Kagan

    Article

    Barnett et al Cell. 2019 Mar 7;176(6):1432-1446.e11. d

    Insert

    TIRAP-ΔNcGAS
    

    Tags

    HA

    Expression

    Mammalian

    Mutation

    cGAS N terminus (aa1-159) replaced with the N ter…

    Promoter

    CMV

    Available Since

    Aug. 27, 2019

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

23. pUCHR-mClover-smAID-P2A-CD5Flag2-bglpA

    Plasmid

    #110654

    Purpose

    Lentiviral vector expressing cell surface Flag-tag and monomeric GFP C-terminaly fused with auxin inducible degron

    Depositor

    Dmitriy Mazurov

    Article

    Zotova et al Sci Rep. 2019 Feb 28;9(1):3132. doi: 10.

    Insert

    mClover-AID-P2A-CD5Flag2-bglpA
    

    Use

    Lentiviral

    Promoter

    CMV

    Available Since

    March 5, 2019

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

24. pUCHR-mClover-smAID-P2A-CD5cmyc2-bglpA

    Plasmid

    #110656

    Purpose

    Lentiviral vector expressing cell surface c-Myc-tag and monomeric GFP C-terminaly fused with auxin inducible degron

    Depositor

    Dmitriy Mazurov

    Article

    Zotova et al Sci Rep. 2019 Feb 28;9(1):3132. doi: 10.

    Insert

    mClover-AID-P2A-CD5cmyc2-bglpA
    

    Use

    Lentiviral

    Promoter

    CMV

    Available Since

    March 5, 2019

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

25. pSG5-chCAR

    Plasmid

    #87231

    Purpose

    Mammalian expression of chicken CAR

    Depositor

    Fritz Rathjen

    Article

    Patzke et al J Neurosci. 2010 Feb 24;30(8):2897-910.

    Insert

    CXADR (CXADR Chicken)
    

    Expression

    Mammalian

    Promoter

    SV40

    Available Since

    Feb. 22, 2017

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

26. Kv7.4 BD (522-645, C643A)/pET28HMT

    Plasmid

    #111073

    Purpose

    Protein expression in E.Coli

    Depositor

    Dan Minor

    Article

    Chang et al Neuron. 2018 Feb 21;97(4):836-852.e6. do

    Insert

    potassium voltage-gated channel subfamily KQT member 4 isoform a [Homo sapiens] (KCNQ4 Human)
    

    Tags

    His Tag and MBP tag

    Expression

    Bacterial

    Mutation

    Kv7.4 BD (522-645, C643A)

    Promoter

    T7

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

27. Kv7.4 (1-645, Δ368-492)/pcDNA3.1

    Plasmid

    #111454

    Purpose

    Electrophysiology in HEK cell

    Depositor

    Dan Minor

    Article

    Chang et al Neuron. 2018 Feb 21;97(4):836-852.e6. do

    Insert

    potassium voltage-gated channel subfamily KQT member 4 isoform a [Homo sapiens] (KCNQ4 Human)
    

    Expression

    Mammalian

    Mutation

    Kv7.4 (1-645, Δ368-492), C643A

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

28. AiP14201: pAAV-AiE0779m_3xC2-minBG-FlpO-WPRE3-BGHpA (Alias: CN4201)

    Plasmid

    #214855

    Purpose

    Expression of FlpO in striatal direct pathway medium spiny neurons (D1 MSNs)

    Depositor

    Allen Institute for Brain Science, Jonathan Ting

    Article

    Hunker et al Neuron. 2025 May 21;113(10):1507-1524.e1

    Insert

    FlpO
    

    Use

    AAV

    Available Since

    July 15, 2024

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

29. AiP14460: pAAV-AiE0452h_3xC2-minBG-SYFP2-WPRE3-BarcodeR-BGHpA (Alias: CN4460)

    Plasmid

    #236599

    Purpose

    Barcoded enhancer AAV vector for multiplexed screening applications; AiE0452h_3xC2 is an enhancer active in striatal D2-MSNs and cortical L5_ET neurons

    Depositor

    Jonathan Ting

    Article

    Hunker et al Neuron. 2025 May 21;113(10):1507-1524.e1

    Insert

    SYFP2
    

    Use

    AAV

    Available Since

    May 14, 2025

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

30. AiP12701: pAAV-hChATp-SYFP2-WPRE3-BGHpA (Alias: CN2701)

    Plasmid

    #236601

    Purpose

    hChATp is a promoter fragment with activity in striatal cholinergic neurons

    Depositor

    Jonathan Ting

    Article

    Hunker et al Neuron. 2025 May 21;113(10):1507-1524.e1

    Insert

    SYFP2
    

    Use

    AAV

    Available Since

    May 14, 2025

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

31. AiP15385: pAAV-AiE0873m_3xC2-minBG-mScarlet-WPRE3-BGHpA (Alias: CN5385)

    Plasmid

    #230875

    Purpose

    AiE0873m_3xC2 is an enhancer sequence, designed to drive AAV-mediated transgene expression in striatal cholinergic interneurons

    Depositor

    Allen Institute for Brain Science, Jonathan Ting

    Article

    Hunker et al Neuron. 2025 May 21;113(10):1507-1524.e1

    Insert

    mScarlet
    

    Use

    AAV

    Expression

    Mammalian

    Available Since

    Jan. 29, 2025

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

32. AiP13401: pAAV-AiE0140h-minBG-FlpO-4X2C-WPRE3-BGHpA (Alias: CN3401)

    Plasmid

    #236585

    Purpose

    AiE0140h is an enhancer sequence, designed to drive AAV-mediated transgene expression in cortical and hippocampal Pvalb neurons

    Depositor

    Jonathan Ting

    Article

    Hunker et al Neuron. 2025 May 21;113(10):1507-1524.e1

    Insert

    AiE0140h-minBG-FlpO-4X2C
    

    Use

    AAV

    Available Since

    May 14, 2025

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

33. AiP15567: pAAV-AiE1419m-minBG-mTFP1-WPRE3-BGHpA (Alias: CN5567)

    Plasmid

    #236584

    Purpose

    AiE1419m is an enhancer sequence, designed to drive AAV-mediated transgene expression in striatal Pvalb-Pthlh neurons

    Depositor

    Jonathan Ting

    Article

    Hunker et al Neuron. 2025 May 21;113(10):1507-1524.e1

    Insert

    AiE1419m-minBG-mTFP1
    

    Use

    AAV

    Available Since

    May 13, 2025

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

34. AiP14455: pAAV-AiE0526h-minBG-SYFP2-WPRE3-BarcodeM-BGHpA (Alias: CN4455)

    Plasmid

    #236594

    Purpose

    Barcoded enhancer AAV vector for multiplexed screening applications; AiE0526h is an enhancer active in striatal MSNs and cortical Sst neurons

    Depositor

    Jonathan Ting

    Article

    Hunker et al Neuron. 2025 May 21;113(10):1507-1524.e1

    Insert

    SYFP2
    

    Use

    AAV

    Available Since

    May 13, 2025

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

35. AiP14530: pAAV-AiE0743m_3xC2-minBG-mTFP1-WPRE3-BGHpA (Alias: CN4530)

    Plasmid

    #230869

    Purpose

    AiE0743m_3xC2 is an enhancer sequence, designed to drive AAV-mediated transgene expression in striatal cholinergic interneurons

    Depositor

    Allen Institute for Brain Science, Jonathan Ting

    Article

    Hunker et al Neuron. 2025 May 21;113(10):1507-1524.e1

    Insert

    mTFP1
    

    Use

    AAV

    Expression

    Mammalian

    Available Since

    Jan. 29, 2025

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

36. AiP14531: pAAV-hDLX_C2.1-minBG-mTFP1-WPRE3-BGHpA (Alias: CN4531)

    Plasmid

    #230870

    Purpose

    hDLX_C2.1 is an enhancer sequence, designed to drive AAV-mediated transgene expression in striatal cholinergic interneurons

    Depositor

    Allen Institute for Brain Science, Jonathan Ting

    Article

    Hunker et al Neuron. 2025 May 21;113(10):1507-1524.e1

    Insert

    mTFP1
    

    Use

    AAV

    Expression

    Mammalian

    Available Since

    Jan. 29, 2025

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

37. AiP15645: pAAV-AiE1426m_3xC1-minBG-SYFP2-WPRE3-BGHpA (Alias: CN5645)

    Plasmid

    #230883

    Purpose

    AiE1426m_3xC1 is an enhancer sequence, designed to drive AAV-mediated transgene expression in striatal Sst-Chodl neurons

    Depositor

    Allen Institute for Brain Science, Jonathan Ting

    Article

    Hunker et al Neuron. 2025 May 21;113(10):1507-1524.e1

    Insert

    SYFP2
    

    Use

    AAV

    Expression

    Mammalian

    Available Since

    Jan. 27, 2025

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

38. AiP14827: pAAV-AiE0441h_3xC2-minBG-jGCaMP8s-WPRE3-BGHpA (Alias: CN4827)

    Plasmid

    #214864

    Purpose

    Expression of jGCaMP8s in striatal medium spiny neurons

    Depositor

    Allen Institute for Brain Science, Jonathan Ting

    Article

    Hunker et al Neuron. 2025 May 21;113(10):1507-1524.e1

    Insert

    jGCaMP8s
    

    Use

    AAV

    Available Since

    July 15, 2024

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

39. AiP14824: pAAV-AiE0441h_3xC2-minBG-iCre-BGHpA (Alias: CN4824)

    Plasmid

    #214861

    Purpose

    Expression of iCre in striatal medium spiny neurons

    Depositor

    Allen Institute for Brain Science, Jonathan Ting

    Article

    Hunker et al Neuron. 2025 May 21;113(10):1507-1524.e1

    Insert

    iCre
    

    Use

    AAV

    Available Since

    July 15, 2024

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

40. AiP14826: pAAV-AiE0441h_3xC2-minBG-FlpO-WPRE3-BGHpA (Alias: CN4826)

    Plasmid

    #214863

    Purpose

    Expression of FlpO in striatal medium spiny neurons

    Depositor

    Allen Institute for Brain Science, Jonathan Ting

    Article

    Hunker et al Neuron. 2025 May 21;113(10):1507-1524.e1

    Insert

    FlpO
    

    Use

    AAV

    Available Since

    July 15, 2024

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

41. AiP12602: pAAV-AiE0769m-minBG-SYFP2-WPRE3-BGHpA (Alias: CN2602)

    Plasmid

    #214841

    Purpose

    Expression of SYFP2 (yellow fluorescent protein) in striatal cholinergic neurons

    Depositor

    Allen Institute for Brain Science, Jonathan Ting

    Article

    Hunker et al Neuron. 2025 May 21;113(10):1507-1524.e1

    Insert

    SYFP2
    

    Use

    AAV

    Available Since

    July 15, 2024

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

42. AiP13118 - pAAV-AiE0367h_C2-minBG-tdTomato-WPRE3-BGHpA (Alias: CN3118)

    Plasmid

    #191730

    Purpose

    AI plasmid ALIAS: AiP13118. Expression of tdTomato in striatal medium spiny neurons

    Depositor

    Allen Institute for Brain Science, Jonathan Ting

    Article

    Hunker et al Neuron. 2025 May 21;113(10):1507-1524.e1

    Insert

    tdTomato
    

    Use

    AAV

    Mutation

    none

    Available Since

    Feb. 1, 2024

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

43. AiP13185 - pAAV-AiE0447h-minBG-dTomato-WPRE3-BGHpA (Alias: CN3185)

    Plasmid

    #191731

    Purpose

    AI plasmid ALIAS: AiP13185. Expression of dTomato in striatal medium spiny neurons

    Depositor

    Allen Institute for Brain Science, Jonathan Ting

    Article

    Hunker et al Neuron. 2025 May 21;113(10):1507-1524.e1

    Insert

    tdTomato
    

    Use

    AAV

    Mutation

    none

    Available Since

    Feb. 1, 2024

    Availability

    Academic Institutions and Nonprofits only

    

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44. pDEST53-LRRK2-WT

    Plasmid

    #25044

    Depositor

    Mark Cookson

    Article

    Greggio et al Neurobiol Dis. 2006 Aug . 23(2):329-41.

    Insert

    LRRK2 (LRRK2 Human)
    

    Tags

    GFP

    Expression

    Mammalian

    Available Since

    June 11, 2010

    Availability

    Academic Institutions and Nonprofits only

    

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45. pDEST53-LRRK2-G2019S

    Plasmid

    #25045

    Depositor

    Mark Cookson

    Article

    Greggio et al Neurobiol Dis. 2006 Aug . 23(2):329-41.

    Insert

    LRRK2 (LRRK2 Human)
    

    Tags

    GFP

    Expression

    Mammalian

    Mutation

    Glycine 2019 mutated to Serine

    Available Since

    June 17, 2010

    Availability

    Academic Institutions and Nonprofits only

    

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46. hZMPSTE24-3FLAG_pQCXIP

    Plasmid

    #89759

    Purpose

    Human ZMPSTE24 mammalian expression vector. Retroviral bicistronic puromycin vector.

    Depositor

    Martin Dorf

    Article

    Fu et al J Exp Med. 2017 Feb 28. pii: jem.2016127

    Insert

    Homo sapiens zinc metallopeptidase STE24 (ZMPSTE24) (ZMPSTE24 Human)
    

    Use

    Retroviral; Bicistronic expression: puromycin re…

    Tags

    9bp spacer (NotI site) - 3xFLAG epitopes - Stop c…

    Expression

    Mammalian

    Mutation

    Y253H in ZMPSTE24 (see depositor comments below)

    Promoter

    CMV

    Available Since

    June 8, 2017

    Availability

    Academic Institutions and Nonprofits only

    

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47. W118-1_hZBTB7B

    Plasmid

    #180380

    Purpose

    lentiviral transduction of human ZBTB7B gene

    Depositor

    Huda Zoghbi

    Article

    Lee et al EMBO J. 2021 Apr 1;40(7):e106106. doi: 1

    Insert

    ZBTB7B (ZBTB7B Human)
    

    Use

    Lentiviral

    Expression

    Mammalian

    Promoter

    CMV

    Available Since

    March 3, 2022

    Availability

    Academic Institutions and Nonprofits only

    

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48. pCMV AURKA-mTurq2

    Plasmid

    #157767

    Purpose

    Expression of AuroraA kinase fused to mTurquoise2 under CMV promoter

    Depositor

    Marc Tramier

    Article

    Bertolin et al eLife. 2018 Aug 2;7. pii: 38111. doi: 10

    Insert

    AURKA (AURKA Human)
    

    Tags

    mTurquoise2

    Expression

    Mammalian

    Promoter

    CMV

    Available Since

    Feb. 10, 2021

    Availability

    Academic Institutions and Nonprofits only

    

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49. pDEST pcDNA5-FRT/TO-eGFP-Rif1

    Plasmid

    #52506

    Purpose

    mammalian expression vector of Rif1 siRNA resistant

    Depositor

    Daniel Durocher

    Article

    Escribano-Diaz et al Mol Cell. 2013 Mar 7;49(5):872-83. doi:

    Insert

    RIF1 (RIF1 Human)
    

    Tags

    eGFP

    Expression

    Mammalian

    Mutation

    siRNA resistant sequence: ATAGTAC

    Available Since

    June 5, 2015

    Availability

    Industry, Academic Institutions, and Nonprofits

    

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50. pcDNA3-ApoE4

    Plasmid

    #197148

    Purpose

    Expresses ApoE4 in Mammalian cell

    Depositor

    Bradley Hyman

    Article

    Hudry et al Sci Transl Med. 2013 Nov 20;5(212):212ra

    Insert

    ApoE4 (APOE Human)
    

    Expression

    Mammalian

    Promoter

    CMV

    Available Since

    March 20, 2023

    Availability

    Academic Institutions and Nonprofits only

    

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