We narrowed to 7,221 results for: ALP

1. pLVX MLKL(S345D)-2A-mCherry-puro

   Plasmid

   #231975

   Purpose

   Tet inducible expression of DmrB-Mlkl with mCherry to induce phosphomimetic MLKL S345D necroptosis

   Depositor

   Brian Ruffell

   Article

   Hanggi et al Cancer Cell. 2024 Nov 13:S1535-6108(24)0

   Insert

   MLKL S345D construct with bi-cistronic mCherry (Mlkl Mouse)
   

   Use

   Lentiviral

   Tags

   Expression

   Mutation

   MLKL S345D

   Promoter

   Available since

   Feb. 7, 2025

   Availability

   Academic Institutions and Nonprofits only

   

   Enlarge

2. 3xFLAG-DGKδ2

   Plasmid

   #226506

   Purpose

   Express N-terminal three tandem FLAG epitope tags, followed by an enterokinase cleavage site and human DGKD gene

   Depositor

   Fumio Sakane, Chiaki Murakami

   Article

   Murakami et al J Biol Chem. 2020 Mar 6;295(10):2932-294

   Insert

   DGKD (DGKD Human)
   

   Use

   Tags

   Three tandem FLAG epitope tag and enterokinase cl…

   Expression

   Mammalian

   Mutation

   Promoter

   CMV

   Available since

   Jan. 6, 2025

   Availability

   Academic Institutions and Nonprofits only

   

   Enlarge

3. HA-MAP4K4-10A

   Plasmid

   #229403

   Purpose

   Lentiviral or overpexression of cDNA

   Depositor

   Christopher Vakoc

   Article

   Klingbeil et al Cancer Discov. 2024 Jul 26. doi: 10.1158

   Insert

   MAP4K4 (MAP4K4 Human)
   

   Use

   Lentiviral

   Tags

   HA

   Expression

   Mammalian

   Mutation

   MARK2 phosphosites (S523,S536,S547,S643,T684,S726…

   Promoter

   EFS

   Available since

   Dec. 12, 2024

   Availability

   Academic Institutions and Nonprofits only

   

   Enlarge

4. HA-MAP4K4-10D

   Plasmid

   #229404

   Purpose

   Lentiviral or overpexression of cDNA

   Depositor

   Christopher Vakoc

   Article

   Klingbeil et al Cancer Discov. 2024 Jul 26. doi: 10.1158

   Insert

   MAP4K4 (MAP4K4 Human)
   

   Use

   Lentiviral

   Tags

   HA

   Expression

   Mammalian

   Mutation

   MARK2 phosphosites (S523,S536,S547,S643,T684,S726…

   Promoter

   EFS

   Available since

   Dec. 12, 2024

   Availability

   Academic Institutions and Nonprofits only

   

   Enlarge

5. pCA528 IST1 L328D (316-366)(C-Cys)

   Plasmid

   #193035

   Purpose

   Bacterial expression plasmid for IST1 (316-366) with C-terminal Cysteine for fluorescence polarization binding assays. Contains L328D mutation that diminishes binding to MIT domains.

   Depositor

   Wesley Sundquist

   Article

   Paine et al Elife. 2023 Sep 29;12:e84515. doi: 10.75

   Insert

   IST1 (IST1 Human)
   

   Use

   Tags

   6xHis-Sumo

   Expression

   Bacterial

   Mutation

   L328D, Residues 316-366, Non-native C-terminal Cy…

   Promoter

   T7

   Available since

   Dec. 9, 2024

   Availability

   Academic Institutions and Nonprofits only

   

   Enlarge

6. pCA528 IST1 L355A (316-366)(C-Cys)

   Plasmid

   #193036

   Purpose

   Bacterial expression plasmid for IST1 (316-366) with C-terminal Cysteine for fluorescence polarization binding assays. Contains L355A mutation that diminishes binding to MIT domains.

   Depositor

   Wesley Sundquist

   Article

   Paine et al Elife. 2023 Sep 29;12:e84515. doi: 10.75

   Insert

   IST1 (IST1 Human)
   

   Use

   Tags

   6xHis-Sumo

   Expression

   Bacterial

   Mutation

   L355A, Residues 316-366, Non-native C-terminal Cy…

   Promoter

   T7

   Available since

   Dec. 9, 2024

   Availability

   Academic Institutions and Nonprofits only

   

   Enlarge

7. pSuper Retro GFP DGK zeta mouse

   Plasmid

   #224577

   Purpose

   Negative Control for downregulation of the expression of human DGK zeta in human cells

   Depositor

   Isabel Mérida

   Article

   Torres-Ayuso et al Oncotarget. 2014 Oct 30;5(20):9710-26. d

   Insert

   sh RNAi Diacylglycerol kinase zeta mouse (Dgkz Mouse)
   

   Use

   RNAi and Retroviral

   Tags

   Expression

   Mutation

   Promoter

   H1

   Available since

   Sept. 19, 2024

   Availability

   Academic Institutions and Nonprofits only

   

   Enlarge

8. pAAV-U6-sgPet-1-hSyn-mCherry-KASH

   Plasmid

   #223227

   Purpose

   guideRNA targeting the mouse Pet-1 (Fev)

   Depositor

   Kyungjin Kim

   Article

   Park et al Commun Biol. 2024 Aug 15;7(1):998. doi:

   Insert

   Fev (Fev Mouse)
   

   Use

   AAV, CRISPR, and Mouse Targeting

   Tags

   mCherry

   Expression

   Mammalian

   Mutation

   Promoter

   U6

   Available since

   Sept. 11, 2024

   Availability

   Academic Institutions and Nonprofits only

   

   Enlarge

9. mTph2p(330bp)-mut1-Luc

   Plasmid

   #223664

   Purpose

   Firefly-luciferase reporter expression driven by proximal 330-bp of mouse Tph2 promoter point mutation at RRE site 1

   Depositor

   Kyungjin Kim

   Article

   Park et al Commun Biol. 2024 Aug 15;7(1):998. doi:

   Insert

   mTph2 promoter (Tph2 Mouse)
   

   Use

   Luciferase

   Tags

   Firefly luciferase

   Expression

   Mammalian

   Mutation

   Promoter

   mTph2 promoter

   Available since

   Sept. 11, 2024

   Availability

   Academic Institutions and Nonprofits only

   

   Enlarge

10. mTph2p(330bp)-mut2-Luc

    Plasmid

    #223665

    Purpose

    Firefly-luciferase reporter expression driven by proximal 330-bp of mouse Tph2 promoter point mutation at RRE site 2

    Depositor

    Kyungjin Kim

    Article

    Park et al Commun Biol. 2024 Aug 15;7(1):998. doi:

    Insert

    mTph2 promoter (Tph2 Mouse)
    

    Use

    Luciferase

    Tags

    Firefly luciferase

    Expression

    Mammalian

    Mutation

    Promoter

    mTph2 promoter

    Available since

    Sept. 11, 2024

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

11. mTph2p(330bp)-mut3-Luc

    Plasmid

    #223666

    Purpose

    Firefly-luciferase reporter expression driven by proximal 330-bp of mouse Tph2 promoter point mutation at PRE site 3

    Depositor

    Kyungjin Kim

    Article

    Park et al Commun Biol. 2024 Aug 15;7(1):998. doi:

    Insert

    mTph2 promoter (Tph2 Mouse)
    

    Use

    Luciferase

    Tags

    Firefly luciferase

    Expression

    Mammalian

    Mutation

    Promoter

    mTph2 promoter

    Available since

    Sept. 11, 2024

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

12. mTph2p(330bp)-mut4-Luc

    Plasmid

    #223667

    Purpose

    Firefly-luciferase reporter expression driven by proximal 330-bp of mouse Tph2 promoter point mutation at PRE site 4

    Depositor

    Kyungjin Kim

    Article

    Park et al Commun Biol. 2024 Aug 15;7(1):998. doi:

    Insert

    mTph2 promoter (Tph2 Mouse)
    

    Use

    Luciferase

    Tags

    Firefly luciferase

    Expression

    Mammalian

    Mutation

    Promoter

    mTph2 promoter

    Available since

    Sept. 11, 2024

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

13. pKLV2-U6gRNA5(RUNX1(13))-PGKpuro2ABFP-W

    Plasmid

    #200501

    Purpose

    Lentiviral vector expressing gRNA targeting human RUNX1

    Depositor

    Kosuke Yusa

    Article

    Aoki et al Blood. 2023 Nov 3:blood.2023020857. doi:

    Insert

    RUNX1(13) (RUNX1 Human)
    

    Use

    Lentiviral

    Tags

    Expression

    Mutation

    Promoter

    Available since

    Jan. 17, 2024

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

14. pKLV2-U6gRNA5(RUNX1(11))-PGKpuro2ABFP-W

    Plasmid

    #200500

    Purpose

    Lentiviral vector expressing gRNA targeting human RUNX1

    Depositor

    Kosuke Yusa

    Article

    Aoki et al Blood. 2023 Nov 3:blood.2023020857. doi:

    Insert

    RUNX1(11) (RUNX1 Human)
    

    Use

    Lentiviral

    Tags

    Expression

    Mutation

    Promoter

    Available since

    Jan. 17, 2024

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

15. CL20_mEGFP_RPS6KB1_VMP1

    Plasmid

    #205913

    Purpose

    Express mEGFP-tagged fusion protein, RPS6KB1_VMP1 from patient-derived sequence

    Depositor

    Richard Kriwacki

    Article

    Tripathi et al Nat Commun. 2023 Sep 28;14(1):6008. doi:

    Insert

    RPS6KB1_VMP1 (RPS6KB1, VMP1 Human)
    

    Use

    Tags

    mEGFP

    Expression

    Mammalian

    Mutation

    Promoter

    Available since

    Nov. 9, 2023

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

16. IL2-mCherry-AH in pmCherryN1

    Plasmid

    #187284

    Purpose

    Express IL2-AH-mCherry

    Depositor

    Alpha Yap

    Article

    Budnar et al Dev Cell. 2019 Jun 17;49(6):894-906.e12.

    Insert

    interleukin-2 receptor alpha-subunit, anillin (IL2, ANLN Human)
    

    Use

    Tags

    mCherry

    Expression

    Mammalian

    Mutation

    AH

    Promoter

    CMV

    Available since

    Sept. 21, 2022

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

17. pITGA5_1745G>U

    Plasmid

    #173812

    Purpose

    mir218 binding site2 point mutation

    Depositor

    Andrew M. Siedlecki

    Article

    Liu et al J Am Soc Nephrol. 2022 Mar;33(3):565-582

    Insert

    NT1745 ITGA5 point mutation (ITGA5 Human)
    

    Use

    Tags

    Expression

    Mammalian

    Mutation

    Promoter

    AmpR

    Available since

    Sept. 9, 2022

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

18. pITGA5_473G>A

    Plasmid

    #173811

    Purpose

    mir218 binding site1 point mutation

    Depositor

    Andrew M. Siedlecki

    Article

    Liu et al J Am Soc Nephrol. 2022 Mar;33(3):565-582

    Insert

    NT473 ITGA5 point mutation (ITGA5 Human)
    

    Use

    Tags

    Expression

    Mammalian

    Mutation

    Promoter

    AmpR

    Available since

    Sept. 9, 2022

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

19. pITGA5_Q853L

    Plasmid

    #174008

    Purpose

    Fibronectin receptor binding site point mutation

    Depositor

    Andrew M. Siedlecki

    Article

    Liu et al J Am Soc Nephrol. 2022 Mar;33(3):565-582

    Insert

    FibronR ITGA5 point mutation (ITGA5 Human)
    

    Use

    Tags

    Expression

    Mammalian

    Mutation

    Promoter

    AmpR

    Available since

    Sept. 6, 2022

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

20. SITS-Cavin4a-mCherry

    Plasmid

    #176022

    Purpose

    Leishmania cell free expression of zebrafish Cavin4a-mCherry. Parton lab clone GWU

    Depositor

    Rob Parton

    Article

    Lo et al J Cell Biol. 2021 Dec 6;220(12). pii: 21

    Insert

    Cavin4a (cavin4a Zebrafish)
    

    Use

    Leishmania cell free expression

    Tags

    mCherry

    Expression

    Mutation

    Promoter

    Available since

    Nov. 4, 2021

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

21. SITS-Cavin4a-EGFP

    Plasmid

    #176018

    Purpose

    Leishmania cell free expression of zebrafish Cavin4a-EGFP. Parton lab clone GRK

    Depositor

    Rob Parton

    Article

    Lo et al J Cell Biol. 2021 Dec 6;220(12). pii: 21

    Insert

    Cavin4a (cavin4a Zebrafish)
    

    Use

    Leishmania cell free expression

    Tags

    Expression

    Mutation

    Promoter

    Available since

    Nov. 4, 2021

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

22. pENTR4 CDS A. thaliana PARP2

    Plasmid

    #175810

    Purpose

    pENTR4 plasmid with CDS of Arabidopsis thaliana POLY(ADP-RIBOSE) POLYMERASE 2 (PARP2, AT4G02390.1) without stop codon for C-terminal epitope tags

    Depositor

    Lennart Wirthmueller

    Article

    Chen et al Front Plant Sci. 2018 Nov 1;9:1581. doi:

    Insert

    PARP2 (PARP2 Mustard Weed)
    

    Use

    Pentr plasmid for gateway cloning

    Tags

    none

    Expression

    Mutation

    Promoter

    none

    Available since

    Oct. 25, 2021

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

23. pZIP-hCMV-ZsGreen-P2A-Puro-IKZF1 sh1

    Plasmid

    #123324

    Purpose

    Lentiviral vector for expression of shRNA targeting IKZF1 from a miR30 embedded casette in the 3'UTR of ZsGreen-P2A-Puro insert

    Depositor

    Eva Gottwein

    Article

    Patil et al Blood. 2018 Aug 9;132(6):577-586. doi: 1

    Insert

    shRNA targeting IKZF1 embedded in miR30 backbone (IKZF1 Human)
    

    Use

    Lentiviral

    Tags

    Expression

    Mammalian

    Mutation

    Promoter

    CMV

    Available since

    March 29, 2019

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

24. pZIP-hCMV-ZsGreen-P2A-Puro-IKZF1 sh2

    Plasmid

    #123325

    Purpose

    Lentiviral vector for expression of shRNA targeting IKZF1 from a miR30 embedded casette in the 3'UTR of ZsGreen-P2A-Puro insert

    Depositor

    Eva Gottwein

    Article

    Patil et al Blood. 2018 Aug 9;132(6):577-586. doi: 1

    Insert

    shRNA targeting IKZF1 embedded in miR30 backbone (IKZF1 Human)
    

    Use

    Lentiviral

    Tags

    Expression

    Mammalian

    Mutation

    Promoter

    CMV

    Available since

    March 29, 2019

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

25. pHAGE-PIK3R1-L372_R373delLR

    Plasmid

    #116598

    Purpose

    Lentiviral expression of PIK3R1 L372_R373delLR

    Depositor

    Kenneth Scott, Gordon Mills

    Article

    Ng et al Cancer Cell. 2018 Mar 12;33(3):450-462.e

    Insert

    PIK3R1 (PIK3R1 Human)
    

    Use

    Lentiviral

    Tags

    Expression

    Mutation

    L372_R373delLR

    Promoter

    Available since

    March 14, 2019

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

26. pHAGE-PIK3R1-L380delL

    Plasmid

    #116599

    Purpose

    Lentiviral expression of PIK3R1 L380delL

    Depositor

    Kenneth Scott, Gordon Mills

    Article

    Ng et al Cancer Cell. 2018 Mar 12;33(3):450-462.e

    Insert

    PIK3R1 (PIK3R1 Human)
    

    Use

    Lentiviral

    Tags

    Expression

    Mutation

    L380delL

    Promoter

    Available since

    March 14, 2019

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

27. pHAGE-PIK3R1-Q302*

    Plasmid

    #116601

    Purpose

    Lentiviral expression of PIK3R1 Q302*

    Depositor

    Kenneth Scott, Gordon Mills

    Article

    Ng et al Cancer Cell. 2018 Mar 12;33(3):450-462.e

    Insert

    PIK3R1 (PIK3R1 Human)
    

    Use

    Lentiviral

    Tags

    Expression

    Mutation

    Q302*

    Promoter

    Available since

    March 14, 2019

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

28. pHAGE-PIK3R1-R348*

    Plasmid

    #116603

    Purpose

    Lentiviral expression of PIK3R1 R348*

    Depositor

    Kenneth Scott, Gordon Mills

    Article

    Ng et al Cancer Cell. 2018 Mar 12;33(3):450-462.e

    Insert

    PIK3R1 (PIK3R1 Human)
    

    Use

    Lentiviral

    Tags

    Expression

    Mutation

    R348*

    Promoter

    Available since

    March 14, 2019

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

29. pHAGE-PIK3R1-R386*

    Plasmid

    #116604

    Purpose

    Lentiviral expression of PIK3R1 R386*

    Depositor

    Kenneth Scott, Gordon Mills

    Article

    Ng et al Cancer Cell. 2018 Mar 12;33(3):450-462.e

    Insert

    PIK3R1 (PIK3R1 Human)
    

    Use

    Lentiviral

    Tags

    Expression

    Mutation

    R386*

    Promoter

    Available since

    March 14, 2019

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

30. pHAGE-PIK3R1-D464N

    Plasmid

    #116584

    Purpose

    Lentiviral expression of PIK3R1 D464N

    Depositor

    Kenneth Scott, Gordon Mills

    Article

    Ng et al Cancer Cell. 2018 Mar 12;33(3):450-462.e

    Insert

    PIK3R1 (PIK3R1 Human)
    

    Use

    Lentiviral

    Tags

    Expression

    Mutation

    D464N

    Promoter

    Available since

    March 14, 2019

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

31. pHAGE-PIK3R1-F398Lfs*6

    Plasmid

    #116589

    Purpose

    Lentiviral expression of PIK3R1 F398Lfs*6

    Depositor

    Kenneth Scott, Gordon Mills

    Article

    Ng et al Cancer Cell. 2018 Mar 12;33(3):450-462.e

    Insert

    PIK3R1 (PIK3R1 Human)
    

    Use

    Lentiviral

    Tags

    Expression

    Mutation

    F398Lfs*6

    Promoter

    Available since

    March 14, 2019

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

32. pHAGE-PIK3R1-G353R

    Plasmid

    #116591

    Purpose

    Lentiviral expression of PIK3R1 G353R

    Depositor

    Kenneth Scott, Gordon Mills

    Article

    Ng et al Cancer Cell. 2018 Mar 12;33(3):450-462.e

    Insert

    PIK3R1 (PIK3R1 Human)
    

    Use

    Lentiviral

    Tags

    Expression

    Mutation

    G353R

    Promoter

    Available since

    March 14, 2019

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

33. pHAGE-PIK3R1-I381Kfs*15

    Plasmid

    #116595

    Purpose

    Lentiviral expression of PIK3R1 I381Kfs*15

    Depositor

    Kenneth Scott, Gordon Mills

    Article

    Ng et al Cancer Cell. 2018 Mar 12;33(3):450-462.e

    Insert

    PIK3R1 (PIK3R1 Human)
    

    Use

    Lentiviral

    Tags

    Expression

    Mutation

    I381Kfs*15

    Promoter

    Available since

    March 14, 2019

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

34. pSN17

    Plasmid

    #100104

    Purpose

    expresses a chimeric OCT4-repressor fusion

    Depositor

    Mark Ptashne

    Article

    Narayan et al Cell Rep. 2017 Aug 15;20(7):1585-1596. d

    Insert

    vexGFP-P2A-OCT4 fused to full length HP1 alpha (POU5F1, CBX5 Human)
    

    Use

    Lentiviral

    Tags

    Expression

    Mammalian

    Mutation

    Promoter

    Available since

    Sept. 7, 2017

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

35. pLuc-Optop38i-dsm

    Plasmid

    #89748

    Purpose

    Expression of light-regulated p38 inhibitor, firefly luciferase-fused, dark-state mutant photosensor (AsLov2Ja.C450A), inhibitor MK3BD3-13F

    Depositor

    Michael Courtney

    Article

    Melero-Fernandez de Mera et al Nat Commun. 2017 May 12;8:15017. doi: 10

    Insert

    Optop38i dark-state mutant
    

    Use

    Luciferase

    Tags

    Firefly luciferase

    Expression

    Mammalian

    Mutation

    C450A mutation of AsLov2Jalpha

    Promoter

    CMV

    Available since

    Aug. 29, 2017

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

36. pDONR223_PPP2R1A_p.W140C

    Plasmid

    #82784

    Purpose

    Gateway Donor vector containing PPP2R1A , part of the Target Accelerator Plasmid Collection.

    Depositor

    Jesse Boehm, Matthew Meyerson, David Root

    Article

    Berger et al Cancer Cell. 2016 Aug 8;30(2):214-28. do

    Insert

    PPP2R1A (PPP2R1A Human)
    

    Use

    Gateway entry vector

    Tags

    Expression

    Mutation

    W140C

    Promoter

    None

    Available since

    April 24, 2017

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

37. pDONR223_PPP2R1A_p.A541G

    Plasmid

    #82771

    Purpose

    Gateway Donor vector containing PPP2R1A , part of the Target Accelerator Plasmid Collection.

    Depositor

    Jesse Boehm, Matthew Meyerson, David Root

    Article

    Berger et al Cancer Cell. 2016 Aug 8;30(2):214-28. do

    Insert

    PPP2R1A (PPP2R1A Human)
    

    Use

    Gateway entry vector

    Tags

    Expression

    Mutation

    A541G

    Promoter

    None

    Available since

    April 24, 2017

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

38. pDONR223_PPP2R1A_p.S143F

    Plasmid

    #81440

    Purpose

    Gateway Donor vector containing PPP2R1A , part of the Target Accelerator Plasmid Collection.

    Depositor

    William Hahn, Jesse Boehm, David Root

    Article

    Kim et al Cancer Discov. 2016 Jul;6(7):714-26. doi

    Insert

    PPP2R1A (PPP2R1A Human)
    

    Use

    Gateway entry vector

    Tags

    Expression

    Mutation

    S143F

    Promoter

    None

    Available since

    April 24, 2017

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

39. pFBD-Btk(PH)Akt1(KD)

    Plasmid

    #86591

    Purpose

    Expresses chimeric fusion of PH domain of Btk and kinase domain of Akt1

    Depositor

    Thomas Leonard, Ivan Yudushkin

    Article

    Ebner et al Mol Cell. 2017 Feb 2;65(3):416-431.e6. d

    Insert

    PH(Btk)-KD(Akt1) fusion (AKT1, BTK Human)
    

    Use

    Tags

    10xHis

    Expression

    Insect

    Mutation

    Promoter

    Available since

    March 7, 2017

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

40. CAMK2A gRNA (BRDN0001162457)

    Plasmid

    #76930

    Purpose

    3rd generation lentiviral gRNA plasmid targeting human CAMK2A

    Depositor

    John Doench, David Root

    Article

    Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

    Insert

    CAMK2A (CAMK2A Human)
    

    Use

    CRISPR and Lentiviral

    Tags

    Expression

    Mammalian

    Mutation

    Promoter

    hU6

    Available since

    July 6, 2016

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

41. PAK1 gRNA (BRDN0001147867)

    Plasmid

    #76465

    Purpose

    3rd generation lentiviral gRNA plasmid targeting human PAK1

    Depositor

    John Doench, David Root

    Article

    Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

    Insert

    PAK1 (PAK1 Human)
    

    Use

    CRISPR and Lentiviral

    Tags

    Expression

    Mammalian

    Mutation

    Promoter

    hU6

    Available since

    July 6, 2016

    Availability

    Academic Institutions and Nonprofits only

    

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42. PAK1 gRNA (BRDN0001145359)

    Plasmid

    #76466

    Purpose

    3rd generation lentiviral gRNA plasmid targeting human PAK1

    Depositor

    John Doench, David Root

    Article

    Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

    Insert

    PAK1 (PAK1 Human)
    

    Use

    CRISPR and Lentiviral

    Tags

    Expression

    Mammalian

    Mutation

    Promoter

    hU6

    Available since

    July 6, 2016

    Availability

    Academic Institutions and Nonprofits only

    

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43. pGL3-mFgf21pro1-luc

    Plasmid

    #101797

    Purpose

    Reporter for mouse Fgf21 promoter activity

    Depositor

    Seiichi Oyadomari

    Article

    Miyake et al FASEB J. 2016 Feb;30(2):798-812. doi: 10

    Insert

    Fibroblast growth factor 21 promoter (Fgf21 Mouse)
    

    Use

    Luciferase

    Tags

    Luciferase

    Expression

    Mammalian

    Mutation

    Promoter

    Available since

    Sept. 27, 2017

    Availability

    Academic Institutions and Nonprofits only

    

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44. pL-CRISPR.EFS.tRFP

    Plasmid

    #57819

    Purpose

    Lentiviral CRISPR-Cas9 delivery for SpCas9 and sgRNA. Coexpresses tagRFP via P2A cleavage site. EFS Promoter driven

    Depositor

    Benjamin Ebert

    Article

    Heckl et al Nat Biotechnol. 2014 Jun 22. doi: 10.103

    Inserts

    SpCas9
    Sp sgRNA scaffold
    EFS (EEF1A1 Human)
    P2A-tRFP
    

    Use

    CRISPR and Lentiviral

    Tags

    FLAG

    Expression

    Mutation

    Promoter

    Available since

    Aug. 20, 2014

    Availability

    Academic Institutions and Nonprofits only

    

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45. CL20_mEGFP_RUNX1_RUNX1T1

    Plasmid

    #205915

    Purpose

    Express mEGFP-tagged fusion protein, RUNX1_RUNX1T1 from patient-derived sequence

    Depositor

    Richard Kriwacki

    Article

    Tripathi et al Nat Commun. 2023 Sep 28;14(1):6008. doi:

    Insert

    RUNX1_RUNX1T1 (RUNX1, RUNX1T1 Human)
    

    Use

    Tags

    mEGFP

    Expression

    Mammalian

    Mutation

    Promoter

    Available since

    Nov. 9, 2023

    Availability

    Academic Institutions and Nonprofits only

    

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46. Beta-2-adrenergic receptor-mRFP

    Plasmid

    #67145

    Purpose

    Beta-2-adrenergic receptor tagged with mRFP on carboxyl terminus

    Depositor

    Catherine Berlot

    Article

    Hynes et al J Biol Chem. 2004 Oct 15;279(42):44101-1

    Insert

    Beta-2-adrenergic receptor-mRFP (ADRB2 Discosoma sp., Human)
    

    Use

    Tags

    mRFP

    Expression

    Mammalian

    Mutation

    Promoter

    CMV

    Available since

    Aug. 6, 2015

    Availability

    Academic Institutions and Nonprofits only

    

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47. MSCV-AML1/ETO-IRES-GFP

    Plasmid

    #60832

    Purpose

    AML1/ETO9a cDNA was generated by PCR from full-length human AML1/ETO-IRES-GFP and subcloned into MSCV-IRES-GFP

    Depositor

    Scott Lowe

    Article

    Zuber et al Genes Dev. 2009 Apr 1;23(7):877-89. doi:

    Insert

    AML1/ETO (RUNX1, RUNX1T1 Human)
    

    Use

    Retroviral

    Tags

    Expression

    Mutation

    Promoter

    Available since

    April 19, 2016

    Availability

    Academic Institutions and Nonprofits only

    

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48. pAAV.CAG.FLEX.iGluSnFR3.v857.PDGFR

    Plasmid

    #196219

    Purpose

    Fluorescent reporter for glutamate, third generation, variant 857 in PDGFR backbone. iGluSnFR3.v857.PDGFR

    Depositor

    Kaspar Podgorski

    Article

    Aggarwal et al Nat Methods. 2023 May 4. doi: 10.1038/s4

    Insert

    pAAV CAG FLEX iGluSnFR3 v857.PDGFR
    

    Use

    AAV, Cre/Lox, Mouse Targeting, and Synthetic Biol…

    Tags

    IgK-chain, Myc epi tag, and PDGFR TM Domain

    Expression

    Mammalian

    Mutation

    Promoter

    Available since

    Aug. 24, 2023

    Availability

    Academic Institutions and Nonprofits only

    

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49. pHAGE-PIK3CA-E545K

    Plasmid

    #116485

    Purpose

    Lentiviral expression of PIK3CA E545K

    Depositor

    Kenneth Scott, Gordon Mills

    Article

    Ng et al Cancer Cell. 2018 Mar 12;33(3):450-462.e

    Insert

    PIK3CA (PIK3CA Human)
    

    Use

    Lentiviral

    Tags

    Expression

    Mutation

    E545K

    Promoter

    Available since

    March 14, 2019

    Availability

    Academic Institutions and Nonprofits only

    

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50. mNeonGreen-LIG3

    Plasmid

    #215143

    Purpose

    Expresses mNeonGreen-LIG3 in mammalian cells from a retroviral vector.

    Depositor

    Michele Pagano

    Article

    Rona et al Mol Cell. 2024 Feb 29:S1097-2765(24)0012

    Insert

    LIG3 (LIG3 Human)
    

    Use

    Retroviral

    Tags

    mNeonGreen

    Expression

    Mammalian

    Mutation

    Promoter

    CMV

    Available since

    April 1, 2024

    Availability

    Academic Institutions and Nonprofits only

    

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