Addgene

371 results

Showing: 91 - 120 of 371 results

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lentiCRISPRv2_ISG

Pooled Library

#125753

Purpose

Expresses gRNAs targeting human Interferon-Stimulated Genes

Depositor

Michael Emerman, Molly OhAinle

Article

Roesch et al Retrovirology. 2018 Mar 20;15(1):26. doi

Expression

Mammalian

Species

Homo sapiens

Use

CRISPR and Lentiviral

Available since

May 7, 2020

Availability

Academic Institutions and Nonprofits only
scQers promoter control #5 (high: EEF1A1 promoter, p028)

Pooled Library

#217424

Purpose

scQers promoter control #5 (high: EEF1A1 promoter, p028)

Depositor

Jay Shendure

Article

Lalanne et al bioRxiv 2022.12.10.519236

Expression

Bacterial and Mammalian

Use

RNAi

Available since

April 3, 2024

Availability

Academic Institutions and Nonprofits only
hCRISPRa-v2, Membrane Proteins (h6), top 5 sgRNAs/gene

Pooled Library

#83985

Purpose

Human CRISPRa Pooled Library targeting membrane proteins

Depositor

Jonathan Weissman

Article

Horlbeck et al Elife. 2016 Sep 23;5. pii: e19760. doi:

Available since

Jan. 12, 2017

Availability

Academic Institutions and Nonprofits only
Mouse Metabolism Library

Pooled Library

#163966

Purpose

Lentiviral CRISPR library targets 2,918 mouse metabolic genes with ~18,000 guide RNAs. The library contains ~6 gRNAs per gene.

Depositor

Alec Kimmelman

Article

Biancur et al Cell Metab. 2020 Oct 28. pii: S1550-4131

Use

CRISPR and Lentiviral

Available since

July 1, 2021

Availability

Academic Institutions and Nonprofits only
Bassik lab Human CRISPR-Cas9 Deletion Library - Drug targets, kinases, phosphatases

Pooled Library

#101927

Purpose

Bassik lab Human CRISPR-Cas9 Deletion Library - Drug targets, kinases, phosphatases. Coexpresses mCherry.

Depositor

Michael Bassik

Article

Morgens et al Nat Commun. 2017 May 5;8:15178. doi: 10.

Expression

Mammalian

Use

CRISPR

Available since

May 23, 2018

Availability

Academic Institutions and Nonprofits only
Lenti-human-UBDUB-gRNA-puromycin-IRES-CFP

Pooled Library

#171531

Purpose

Pooled gRNA library against human ubiquitination and de-ubiquitination complex genes (UBDUB)

Depositor

Chunliang Li

Article

Wright et al Proc Natl Acad Sci U S A. 2023 Apr 18;12

Expression

Mammalian

Species

Homo sapiens

Use

Lentiviral

Available since

June 22, 2021

Availability

Academic Institutions and Nonprofits only
Inzolia library in pRDA_052

Pooled Library

#209551

Purpose

The human, genome-wide, CRISPR knockout enAsCas12a gRNA library targets single genes and paralog pairs, triples, and quads with arrays of 4 gRNAs.

Depositor

John Doench

Article

Esmaeili Anvar et al Nat Commun. 2024 Apr 27;15(1):3577. doi:

Use

CRISPR and Lentiviral

Available since

Dec. 5, 2023

Availability

Academic Institutions and Nonprofits only
FNLCR CRISPRa Cell Surface and FNLCR CRISPRa Soluble Libraries

Pooled Library

#1000000228

Depositor

Raj Chari

Available since

Jan. 24, 2024

Availability

Academic Institutions and Nonprofits only
Bassik lab Mouse CRISPR-Cas9 Deletion Library - Drug targets, kinases, phosphatases

Pooled Library

#1000000122

Purpose

CRISPR gRNA mouse knockout pooled library - Drug targets, kinases, phosphatases

Depositor

Michael Bassik

Available since

May 23, 2018

Availability

Academic Institutions and Nonprofits only
Pan-cancer CasRx lncRNA Albarossa library

Pooled Library

#212966

Purpose

The human CasRx CRISPR lentiviral library encodes 75,725 gRNA arrays (two gRNAs per array) targeting 24,171 lncRNAs.

Depositor

Roland Rad

Article

Montero et al Nat Methods. 2024 Feb 26. doi: 10.1038/s

Expression

Mammalian

Use

CRISPR and Lentiviral

Available since

Feb. 21, 2024

Availability

Academic Institutions and Nonprofits only
Human DNA Binding Domain-Focused CRISPR Knockout Library

Pooled Library

#123334

Purpose

Expresses gRNA targeting the DNA binding domain of human transcription factors.

Depositor

Christopher Vakoc

Article

Huang et al Genes Dev. 2018 Jul 1;32(13-14):915-928.

Expression

Mammalian

Species

Homo sapiens

Use

CRISPR and Lentiviral

Available since

May 2, 2019

Availability

Academic Institutions and Nonprofits only
STICR_Index1

Pooled Library

#186334

Purpose

High Complexity Lentiviral Barcode Library

Depositor

Tomasz Nowakowski

Article

Delgado et al Nature. 2021 Dec 15. pii: 10.1038/s41586

Expression

Mammalian

Species

Synthetic

Use

Lentiviral

Available since

Sept. 12, 2022

Availability

Academic Institutions and Nonprofits only
Human SLC overexpression library

Pooled Library

#213694

Purpose

Inducible barcoded library with 467 codon-optimized cDNAs with UMIs to test the impact of SLC transporters on biological processes.

Depositor

Giulio Superti-Furga, RESOLUTE Consortium

Article

Wolf et al Cell Chem Biol. 2024 Dec 24:S2451-9456(2

Expression

Mammalian

Species

Homo sapiens

Use

Lentiviral

Available since

Aug. 30, 2024

Availability

Academic Institutions and Nonprofits only
Human Brunello kinome pooled library, guides 1-8 in lentiCRISPRv2 backbone

Pooled Library

#1000000083

Purpose

CRISPR gRNA knockout pooled library for targeting the human kinome

Depositor

John Doench, David Root

Available since

June 27, 2016

Availability

Academic Institutions and Nonprofits only
mCRISPRa-v2, Membrane Proteins (m6), top 5 sgRNAs/gene

Pooled Library

#84003

Purpose

Mouse CRISPRa Pooled Library targeting membrane proteins

Depositor

Jonathan Weissman

Article

Horlbeck et al Elife. 2016 Sep 23;5. pii: e19760. doi:

Available since

Jan. 12, 2017

Availability

Academic Institutions and Nonprofits only
Inzolia library in pRDA_550

Pooled Library

#209552

Purpose

The human, genome-wide, CRISPR knockout enAsCas12a gRNA library targets single genes and paralog pairs, triples, and quads with arrays of 4 gRNAs.

Depositor

John Doench

Article

Esmaeili Anvar et al Nat Commun. 2024 Apr 27;15(1):3577. doi:

Use

CRISPR and Lentiviral

Available since

Dec. 5, 2023

Availability

Academic Institutions and Nonprofits only
E.coli_GW-sgRNA_Lib3

Pooled Library

#113136

Purpose

Genome-wide gRNA library for E. coli, sub3

Depositor

Chong Zhang

Article

Wang et al Nat Commun. 2018 Jun 26;9(1):2475. doi:

Expression

Bacterial

Available since

May 14, 2019

Availability

Academic Institutions and Nonprofits only
E.coli_GW-sgRNA_Lib1

Pooled Library

#113134

Purpose

Genome-wide gRNA library for E. coli, sub1

Depositor

Chong Zhang

Article

Wang et al Nat Commun. 2018 Jun 26;9(1):2475. doi:

Expression

Bacterial

Available since

May 14, 2019

Availability

Academic Institutions and Nonprofits only
E.coli_GW-sgRNA_Lib4

Pooled Library

#113137

Purpose

Genome-wide gRNA library for E. coli, sub4

Depositor

Chong Zhang

Article

Wang et al Nat Commun. 2018 Jun 26;9(1):2475. doi:

Expression

Bacterial

Available since

May 14, 2019

Availability

Academic Institutions and Nonprofits only
E.coli_GW-sgRNA_Lib2

Pooled Library

#113135

Purpose

Genome-wide gRNA library for E. coli, sub2

Depositor

Chong Zhang

Article

Wang et al Nat Commun. 2018 Jun 26;9(1):2475. doi:

Expression

Bacterial

Available since

May 14, 2019

Availability

Academic Institutions and Nonprofits only
E.coli_NC_sgRNA_lib

Pooled Library

#113146

Purpose

Genome-wide gRNA library for E. coli, non-targeting control

Depositor

Chong Zhang

Article

Wang et al Nat Commun. 2018 Jun 26;9(1):2475. doi:

Expression

Bacterial

Available since

May 14, 2019

Availability

Academic Institutions and Nonprofits only
hCRISPRi-v2, Kinases, Phosphatases, and Drug Targets (h1), top 5 sgRNAs/gene

Pooled Library

#83971

Purpose

Human CRISPRi Pooled Library tartgeting kinsases, phosphatases and Drug Targets

Depositor

Jonathan Weissman

Article

Horlbeck et al Elife. 2016 Sep 23;5. pii: e19760. doi:

Available since

Dec. 14, 2016

Availability

Academic Institutions and Nonprofits only
SPECS library

Pooled Library

#127842

Purpose

For performing high-throughput cell state-specific synthetic promoter screening

Depositor

Timothy Lu

Article

Wu et al Nat Commun. 2019 Jun 28;10(1):2880. doi:

Species

Synthetic

Use

Lentiviral

Available since

Aug. 22, 2020

Availability

Academic Institutions and Nonprofits only
Xiaole Shirley Liu lab Human CRISPR lentiviral library

Pooled Library

#1000000132

Purpose

CRISPR gRNA knockout pooled library for targeting the human genome

Depositor

Xiaole Shirley Liu

Available since

June 13, 2018

Availability

Academic Institutions and Nonprofits only
Ingolia lab S cerevisiae CRISPRi v1 – barcodes 181005

Pooled Library

#161769

Purpose

Inducible CRISPRi library

Depositor

Nicholas Ingolia

Article

McGlincy et al BMC Genomics. 2021 Mar 23;22(1):205. doi

Expression

Yeast

Species

Saccharomyces cerevisiae

Use

CRISPR

Available since

Nov. 30, 2021

Availability

Academic Institutions and Nonprofits only
Mouse Metabolic Gene CRISPRa sgRNA library

Pooled Library

#187081

Purpose

Lentiviral CRISPRa library targeting mouse metabolic genes for activation of gene expression

Depositor

Kivanc Birsoy

Article

Unlu et al Mol Cell. 2022 Aug 4;82(15):2832-2843.e7

Expression

Mammalian

Species

Mus musculus

Use

Lentiviral

Available since

Oct. 26, 2022

Availability

Academic Institutions and Nonprofits only
mCRISPRi-v2, genome-wide, 10 sgRNAs/gene

Pooled Library

#1000000092

Purpose

Genome-wide CRISPR gRNA pooled library for inhibition of mouse genes

Depositor

Jonathan Weissman

Available since

Nov. 15, 2016

Availability

Academic Institutions and Nonprofits only
Bassik lab Human CRISPR-Cas9 Deletion Library - Unassigned1

Pooled Library

#101932

Purpose

Bassik lab Human CRISPR-Cas9 Deletion Library - Unassigned1. Coexpresses mCherry.

Depositor

Michael Bassik

Article

Morgens et al Nat Commun. 2017 May 5;8:15178. doi: 10.

Expression

Mammalian

Use

CRISPR

Available since

May 23, 2018

Availability

Academic Institutions and Nonprofits only
Bassik lab Human CRISPR-Cas9 Deletion Library - Apoptosis and cancer

Pooled Library

#101926

Purpose

Bassik lab Human CRISPR-Cas9 Deletion Library - Apoptosis and cancer. Coexpresses mCherry.

Depositor

Michael Bassik

Article

Morgens et al Nat Commun. 2017 May 5;8:15178. doi: 10.

Expression

Mammalian

Use

CRISPR

Available since

May 23, 2018

Availability

Academic Institutions and Nonprofits only
Dual sgRNA CRISPRa Library

Pooled Library

#1000000193

Depositor

Jonathan Weissman

Available since

Sept. 30, 2022

Availability

Academic Institutions and Nonprofits only

Showing: 91 - 120 of 371 results

Results per page:

Sort results by:

lentiCRISPRv2_ISG

scQers promoter control #5 (high: EEF1A1 promoter, p028)

hCRISPRa-v2, Membrane Proteins (h6), top 5 sgRNAs/gene

Mouse Metabolism Library

Bassik lab Human CRISPR-Cas9 Deletion Library - Drug targets, kinases, phosphatases

Lenti-human-UBDUB-gRNA-puromycin-IRES-CFP

Inzolia library in pRDA_052

FNLCR CRISPRa Cell Surface and FNLCR CRISPRa Soluble Libraries

Bassik lab Mouse CRISPR-Cas9 Deletion Library - Drug targets, kinases, phosphatases

Pan-cancer CasRx lncRNA Albarossa library

Human DNA Binding Domain-Focused CRISPR Knockout Library

STICR_Index1

Human SLC overexpression library

Human Brunello kinome pooled library, guides 1-8 in lentiCRISPRv2 backbone

mCRISPRa-v2, Membrane Proteins (m6), top 5 sgRNAs/gene

Inzolia library in pRDA_550

E.coli_GW-sgRNA_Lib3

E.coli_GW-sgRNA_Lib1

E.coli_GW-sgRNA_Lib4

E.coli_GW-sgRNA_Lib2

E.coli_NC_sgRNA_lib

hCRISPRi-v2, Kinases, Phosphatases, and Drug Targets (h1), top 5 sgRNAs/gene

SPECS library

Xiaole Shirley Liu lab Human CRISPR lentiviral library

Ingolia lab S cerevisiae CRISPRi v1 – barcodes 181005

Mouse Metabolic Gene CRISPRa sgRNA library

mCRISPRi-v2, genome-wide, 10 sgRNAs/gene

Bassik lab Human CRISPR-Cas9 Deletion Library - Unassigned1

Bassik lab Human CRISPR-Cas9 Deletion Library - Apoptosis and cancer

Dual sgRNA CRISPRa Library

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