405 results

#209551

The human, genome-wide, CRISPR knockout enAsCas12a gRNA library targets single genes and paralog pairs, triples, and quads with arrays of 4 gRNAs.

John Doench

Esmaeili Anvar et al Nat Commun. 2024 Apr 27;15(1):3577. doi:

Dec. 5, 2023

Academic Institutions and Nonprofits only

#187081

Library targeting 2,989 mouse metabolic genes for activation of gene expression.

Kivanc Birsoy

Unlu et al Mol Cell. 2022 Aug 4;82(15):2832-2843.e7

Oct. 26, 2022

Academic Institutions and Nonprofits only

#163955

Targets open reading frames and non-coding RNAs in M. smegmatis.

Jeremy Rock

Bosch et al Cell. 2021 Jul 16. pii: S0092-8674(21)00

Oct. 1, 2021

Academic Institutions and Nonprofits only

#1000000082

CRISPR gRNA knockout pooled library for targeting the human kinome

John Doench, David Root

June 27, 2016

Academic Institutions and Nonprofits only

#51048

Sub-pool of Sabatini/Lander sgRNA library enriched for control targets.

Eric Lander, David Sabatini

Wang et al Science. 2014 Jan 3;343(6166):80-4. doi:

Feb. 7, 2014

Academic Institutions and Nonprofits only

#1000000228

Raj Chari

Jan. 24, 2024

Academic Institutions and Nonprofits only

#1000000273

Erika DeBenedictis

April 29, 2026

Academic Institutions and Nonprofits only

#83981

Human CRISPRa Pooled Library targeting cancer and apoptosis genes

Jonathan Weissman

Horlbeck et al Elife. 2016 Sep 23;5. pii: e19760. doi:

Jan. 12, 2017

Academic Institutions and Nonprofits only

#83984

Human CRISPRa Pooled Library targeting gene expression

Jonathan Weissman

Horlbeck et al Elife. 2016 Sep 23;5. pii: e19760. doi:

Jan. 12, 2017

Academic Institutions and Nonprofits only

#101929

Bassik lab Human CRISPR-Cas9 Deletion Library - Membrane proteins. Coexpresses mCherry.

Michael Bassik

Morgens et al Nat Commun. 2017 May 5;8:15178. doi: 10.

May 23, 2018

Academic Institutions and Nonprofits only

#92386

Crispri

John Doench, David Root

Sanson et al Nat Commun. 2018 Dec 21;9(1):5416. doi:

July 13, 2018

Academic Institutions and Nonprofits only

#1000000193

Jonathan Weissman

Sept. 30, 2022

Academic Institutions and Nonprofits only

#67988

Knockout library targeting 18,424 mouse genes. gRNAs were improved using a new design pipeline and improved gRNA scaffold.

Kosuke Yusa

Tzelepis et al Cell Rep. 2016 Oct 18;17(4):1193-1205. d

Oct. 14, 2016

Academic Institutions and Nonprofits only

#117725

Designed for genomic deletion screening of protein kinases by targeting the kinase domains.

Christopher Vakoc

Tarumoto et al Mol Cell. 2018 Feb 28. pii: S1097-2765(1

Jan. 4, 2019

Academic Institutions and Nonprofits only

#112200

Targets 1,594 primary human miRNA genes. The library contains 4-5 gRNAs per gene and 1,000 non-targeting control gRNAs for a total of 8,382 gRNAs.

Ren-Jang Lin

Kurata et al RNA. 2018 May 2. pii: rna.066282.118. do

Sept. 20, 2018

Academic Institutions and Nonprofits only

#115927

~93,000 gRNAs targeting random positions along the genome of E. coli MG1655 with a NGG PAM motif. Contains ~19 targets per gene and can be used with SpdCas9 to perform pooled CRISPRi screens.

David Bikard

Cui et al Nat Commun. 2018 May 15;9(1):1912. doi:

June 6, 2019

Academic Institutions and Nonprofits only

#83996

Version 2 of the mouse CRISPRa genome wide library

Jonathan Weissman

Horlbeck et al Elife. 2016 Sep 23;5. pii: e19760. doi:

Nov. 15, 2016

Academic Institutions and Nonprofits only

#125517

Human CRISPR lentiviral library containing 70,948 guides (4-5 guides/gene) targeting 18,053 human protein-coding genes, in a non-Cas9 containing backbone

Jason Moffat

Mair et al Cell Rep. 2019 Apr 9;27(2):599-615.e12.

Aug. 1, 2019

Academic Institutions and Nonprofits only

#213694

Inducible barcoded library with 467 codon-optimized cDNAs with UMIs to test the impact of SLC transporters on biological processes.

RESOLUTE Consortium, Giulio Superti-Furga

Wolf et al Cell Chem Biol. 2024 Dec 24:S2451-9456(2

Aug. 30, 2024

Academic Institutions and Nonprofits only

#177663

CRISPR-interference (CRISPRi) library of 1,573 sgRNAs targeting 476 genes encoding factors involved in DNA repair and associated processes

Brittany Adamson

Hussmann et al Cell. 2021 Oct 28;184(22):5653-5669.e25.

July 11, 2023

Academic Institutions and Nonprofits only

#123334

Designed for genomic deletion screening of transcription factors by targeting the DNA binding domains.

Christopher Vakoc

Huang et al Genes Dev. 2018 Jul 1;32(13-14):915-928.

May 2, 2019

Academic Institutions and Nonprofits only

#179774

SPLINTR (Single-cell Profiling and LINeage TRacing) is a high diversity lentiviral barcode library for tracing clonal lineages using bulk and single-cell readouts.

Mark Dawson

Fennell et al Nature. 2022 Jan;601(7891):125-131. doi:

May 11, 2022

Academic Institutions and Nonprofits only

#83980

Human CRISPRa Pooled Library tartgeting kinsases, phosphatases and Drug Targets

Jonathan Weissman

Horlbeck et al Elife. 2016 Sep 23;5. pii: e19760. doi:

Jan. 12, 2017

Academic Institutions and Nonprofits only

#179776

SPLINTR (Single-cell Profiling and LINeage TRacing) is a high diversity lentiviral barcode library for tracing clonal lineages using bulk and single-cell readouts.

Mark Dawson

Fennell et al Nature. 2022 Jan;601(7891):125-131. doi:

May 11, 2022

Academic Institutions and Nonprofits only

#1000000075

Genome-wide CRISPR gRNA pooled library for activation of mouse genes

Feng Zhang

March 17, 2016

Academic Institutions and Nonprofits only

#85968

Barcode library for cloning gRNA sublibraries for single cell CRISPR analysis.

Jonathan Weissman

Adamson et al Cell. 2016 Dec 15;167(7):1867-1882.e21.

Feb. 14, 2017

Academic Institutions and Nonprofits only

#1000000083

CRISPR gRNA knockout pooled library for targeting the human kinome

John Doench, David Root

June 27, 2016

Academic Institutions and Nonprofits only

#1000000096

CRISPR gRNA knockout pooled library for targeting the mouse genome

Eric Lander, David Sabatini

April 3, 2017

Academic Institutions and Nonprofits only

#233213

Barcoding pooled library

Alejo Rodriguez-Fraticelli

Singh et al Cell Stem Cell. 2025 Feb 19:S1934-5909(2

March 6, 2025

Academic Institutions and Nonprofits only

#1000000122

CRISPR gRNA mouse knockout pooled library - Drug targets, kinases, phosphatases

Michael Bassik

May 23, 2018

Academic Institutions and Nonprofits only