167,642 results

1. MAC_N_FEV

   Plasmid

   #167757

   Purpose

   Expresses FEV in mammalian cells

   Depositor

   Markku Varjosalo

   Article

   Goos et al Nat Commun. 2022 Feb 9;13(1):766. doi: 1

   Insert

   FEV (FEV Human)
   

   Tags

   MAC

   Expression

   Mammalian

   Mutation

   no mutations

   Available Since

   Jan. 24, 2022

   Availability

   Academic Institutions and Nonprofits only

   

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2. pMax_GFP

   Plasmid

   #177825

   Purpose

   Host Cell Reactivation (HCR) control GFP plasmid (pMax backbone)

   Depositor

   Leona Samson, Zachary Nagel

   Article

   Nagel et al Proc Natl Acad Sci U S A. 2014 May 6;111

   Insert

   GFP
   

   Expression

   Mammalian

   Promoter

   CMV

   Available Since

   Dec. 21, 2022

   Availability

   Academic Institutions and Nonprofits only

   

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3. TRIM33-GFP

   Plasmid

   #65399

   Purpose

   GFP-tagged BRD protein, which can be used to be expressed in mammalian cells.

   Depositor

   Kyle Miller

   Article

   Gong et al Genes Dev. 2015 Jan 15;29(2):197-211. do

   Insert

   TRIM33 (TRIM33 Human)
   

   Tags

   EmGFP

   Expression

   Mammalian

   Mutation

   none

   Promoter

   CMV

   Available Since

   May 13, 2015

   Availability

   Academic Institutions and Nonprofits only

   

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4. pcDNA3-mRFP

   Plasmid

   #13032

   Purpose

   Mammalian expression vector for cloning your gene fused to mRFP

   Depositor

   Doug Golenbock

   Has Service

   Cloning Grade DNA

   Insert

   Monomer Red Fluorescent Protein
   

   Expression

   Mammalian

   Available Since

   Nov. 7, 2006

   Availability

   Academic Institutions and Nonprofits only

   

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5. pCMV-LAMP1-mCherry

   Plasmid

   #214274

   Purpose

   Mammalian expression of LAMP1-mCherry (lysosome marker)

   Depositor

   Shinya Tsukiji

   Article

   Ajiki et al RSC Chem Biol. 2024 Apr 24;5(6):544-555.

   Insert

   LAMP1-mCherry (Lamp1 Rat)
   

   Expression

   Mammalian

   Promoter

   CMV

   Available Since

   Feb. 21, 2024

   Availability

   Academic Institutions and Nonprofits only

   

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6. pcDNA3.1-hnRNPU-V5

   Plasmid

   #35974

   Depositor

   Susana Valente

   Article

   Mediouni et al Curr HIV Res. 2015;13(1):64-79.

   Insert

   heterogeneous nuclear ribonucleoprotein U (HNRNPU Human)
   

   Tags

   V5

   Expression

   Mammalian

   Available Since

   April 10, 2018

   Availability

   Academic Institutions and Nonprofits only

   

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7. pBW2614_pCAG-PV1-GAI-L2-28-396-FlpO-ABI-NLS-BGHpA

   Plasmid

   #108833

   Purpose

   Expresses aa28 to aa396 of Flp recombinase fused to GAI and ABI CIDs

   Depositor

   Wilson Wong

   Article

   Weinberg et al Nat Commun. 2019 Oct 24;10(1):4845. doi:

   Insert

   Flp recombinase fragment aa28 to aa396
   

   Use

   Cre/Lox and Synthetic Biology

   Tags

   ABI,NLS and GAI

   Expression

   Mammalian

   Promoter

   pCAG

   Available Since

   Aug. 28, 2019

   Availability

   Academic Institutions and Nonprofits only

   

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8. pRRL-SFFV-rtTA3-IRES-Luc-P2A-mtagBFP

   Plasmid

   #176027

   Purpose

   construct expresses the reverse tet-responsive transactivator 3 (rtTA3) together with Luciferase (Luc) for bioluminescence in vivo imaging, and mTaqBFP for enriching transgenic cells by flow cytometry

   Depositor

   Irmela Jeremias

   Article

   Liu et al Biomark Res. 2020 Sep 16;8:46. doi: 10.1

   Inserts

   rtTA3
   Luc2
   mtagBFP
   

   Use

   Lentiviral

   Available Since

   Jan. 3, 2022

   Availability

   Academic Institutions and Nonprofits only

   

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9. mCherry-VAPB

   Plasmid

   #108126

   Purpose

   ER marker

   Depositor

   Gerry Hammond

   Article

   Zewe et al Elife. 2018 Feb 20;7. pii: 35588. doi: 1

   Insert

   mCherry:VAPB (VAPB Human)
   

   Expression

   Mammalian

   Promoter

   CMV

   Available Since

   April 4, 2018

   Availability

   Academic Institutions and Nonprofits only

   

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10. pAAV-hSyn1-FLEX-NEPLDCV-P2A-mRUBY3-WPRE

    Plasmid

    #207664

    Purpose

    Neuropeptide degradation

    Depositor

    Sung Han

    Article

    Kim et al bioRxiv 2023.01.19.524797

    Insert

    NEP (MME Human)
    

    Use

    AAV and Cre/Lox

    Tags

    mRUBY3

    Mutation

    Addition of signaling peptide (POMC) on the N-ter…

    Promoter

    hSynapsin

    Available Since

    Dec. 6, 2023

    Availability

    Academic Institutions and Nonprofits only

    

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11. MSGV-1D3-28Z All ITAMs intact

    Plasmid

    #107226

    Purpose

    Anti-mouse CD19 CAR with CD3 ITAMs intact

    Depositor

    Steven Rosenberg, James Kochenderfer

    Article

    Kochenderfer et al Blood. 2010 Nov 11;116(19):3875-86. doi:

    Insert

    1D3-28Z All ITAMs intact
    

    Use

    Retroviral

    Tags

    None

    Mutation

    None

    Available Since

    March 30, 2018

    Availability

    Academic Institutions and Nonprofits only

    

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12. pExp-His-zBasic-RBD

    Plasmid

    #194999

    Purpose

    Production of SARS-CoV2 receptor binding domain in E. coli

    Depositor

    Marko Hyvönen

    Article

    Gaynor et al Nat Commun. 2023 Jun 16;14(1):3583. doi:

    Insert

    RBD (S SARS-CoV-2)
    

    Tags

    His8-Zbasic

    Expression

    Bacterial

    Promoter

    T7lac

    Available Since

    Jan. 27, 2023

    Availability

    Academic Institutions and Nonprofits only

    

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13. RF-118-UB-BRCA1

    Plasmid

    #78960

    Purpose

    Expression of the C-terminal fragment of BRCA1 that is endogenously generated by caspase cleavage in mammalian cells

    Depositor

    Richard Fahlman

    Article

    Xu et al J Biol Chem. 2012 Mar 2;287(10):7495-502

    Insert

    BRCA1 (BRCA1 Human)
    

    Tags

    3x Flag and ubiquitin

    Expression

    Mammalian

    Mutation

    delta 1-1155

    Promoter

    CMV

    Available Since

    March 8, 2017

    Availability

    Academic Institutions and Nonprofits only

    

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14. pcDNA3.1/opto-a1AR-EYFP

    Plasmid

    #20947

    Purpose

    Mammalian expression of opto-a1AR fused to EYFP for optical control of GPCR signaling

    Depositor

    Karl Deisseroth

    Article

    Airan et al Nature. 2009 Apr 23;458(7241):1025-9. do

    Insert

    opto-a1AR
    

    Expression

    Mammalian

    Available Since

    May 28, 2009

    Availability

    Academic Institutions and Nonprofits only

    

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15. pNP3254 [pNP2922 - ISCro4 Enhanced DBL (DBL3, WT) + ISCro4 Recombianse (WT]

    Plasmid

    #247257

    Purpose

    Express ISCro4 recombinase and bridge RNA

    Depositor

    Patrick Hsu

    Article

    Perry et al Science. 2025 Sep 25:eadz0276. doi: 10.1

    Insert

    pNP2922 - ISCro4 bRNA101-179 ins179(rc(101-111) (DBL3)
    

    Expression

    Mammalian

    Mutation

    ins179(rc(101-111)

    Available Since

    Oct. 23, 2025

    Availability

    Academic Institutions and Nonprofits only

    

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16. pNP3386 [For use in genome insertion and off-target assessment]

    Plasmid

    #247258

    Purpose

    Example plasmid for bridge recombinase mediated insertion and off-target assessment with puromycin selection — must clone in UMI

    Depositor

    Patrick Hsu

    Article

    Perry et al Science. 2025 Sep 25:eadz0276. doi: 10.1

    Insert

    ISCro4 Recognition Site-UMI-Ef1a-PuroR-P2A-mCherry (Plasmid for Insertion Site Mapping [Example, Clone in Sequence + UMI])
    

    Expression

    Mammalian

    Available Since

    Oct. 23, 2025

    Availability

    Academic Institutions and Nonprofits only

    

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17. pvPE-V2

    Plasmid

    #240286

    Purpose

    Encodes second generation porcine endogenous retrovirus-derived prime editing (pvPE) system into mammalian cells for gene editing.

    Depositor

    Lusheng Huang

    Article

    Liu et al Trends Biotechnol. 2025 Aug 30:S0167-779

    Insert

    pvPE-V2
    

    Use

    CRISPR

    Tags

    SV40 NLS

    Expression

    Mammalian

    Promoter

    CMV

    Available Since

    Oct. 8, 2025

    Availability

    Academic Institutions and Nonprofits only

    

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18. pvPE-V3

    Plasmid

    #240287

    Purpose

    Encodes third generation porcine endogenous retrovirus-derived prime editing (pvPE) system into mammalian cells for gene editing.

    Depositor

    Lusheng Huang

    Article

    Liu et al Trends Biotechnol. 2025 Aug 30:S0167-779

    Insert

    pvPE-V3
    

    Use

    CRISPR

    Tags

    SV40 NLS

    Expression

    Mammalian

    Promoter

    CMV

    Available Since

    Oct. 8, 2025

    Availability

    Academic Institutions and Nonprofits only

    

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19. Jacquere (all-in-one vector)

    Pooled Library

    #247027

    Purpose

    Human genome-wide CRISPR knockout library for the use of S. pyogenes Cas9. Each gene is targeted by 3 constructs.

    Depositor

    John Doench, David Root

    Article

    Drepanos et al bioRxiv 2025.08.26.672375; doi: https://

    Expression

    Mammalian

    Species

    Homo sapiens

    Use

    CRISPR and Lentiviral

    Available Since

    Oct. 2, 2025

    Availability

    Academic Institutions and Nonprofits only

20. NPY EGFP

    Plasmid

    #245034

    Purpose

    Secretory granule marker for endocrine cells

    Depositor

    Thomas Martin

    Insert

    NPY (NPY Human)
    

    Tags

    EGFP

    Expression

    Mammalian

    Available Since

    Sept. 30, 2025

    Availability

    Academic Institutions and Nonprofits only

    

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21. NanoLuc-BAZ2A Fusion Vector

    Plasmid

    #238659

    Purpose

    Express NanoLuc-BAZ2A Fusion Protein in Mammalian Cells under a CMV promoter

    Depositor

    Promega Corporation

    Has Service

    DNA

    Insert

    BAZ2A (BAZ2A Human)
    

    Tags

    NanoLuc (R)

    Expression

    Mammalian

    Mutation

    None

    Promoter

    CMV

    Available Since

    Sept. 14, 2025

    Availability

    Industry, Academic Institutions, and Nonprofits

    

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22. NanoLuc-EP300 Fusion Vector

    Plasmid

    #238648

    Purpose

    Express NanoLuc-EP300 Fusion Protein in Mammalian Cells under a CMV promoter

    Depositor

    Promega Corporation

    Has Service

    DNA

    Insert

    EP300 (EP300 Human)
    

    Tags

    NanoLuc (R)

    Expression

    Mammalian

    Mutation

    None

    Promoter

    CMV

    Available Since

    Sept. 14, 2025

    Availability

    Industry, Academic Institutions, and Nonprofits

    

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23. pcDNA-DEST47-SIRT1

    Plasmid

    #242131

    Purpose

    Expression in mammalian cells

    Depositor

    Izumi Horikawa, J. Carl Barrett

    Article

    Michishita et al Mol Biol Cell. 2005 Oct;16(10):4623-35.

    Insert

    SIRT1 (SIRT1 Human)
    

    Tags

    Cycle 3 GFP

    Expression

    Mammalian

    Promoter

    CMV

    Available Since

    Aug. 19, 2025

    Availability

    Academic Institutions and Nonprofits only

    

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24. pLenti-CMV-MFSD6-mNeon-Puro

    Plasmid

    #239955

    Purpose

    Lentiviral vector to generate mNeon-tagged MFSD6 stable expressing cell line under CMV promoter

    Depositor

    Jan Carette

    Article

    Varanese et al Nature. 2025 Mar 25. doi: 10.1038/s41586

    Insert

    MFSD6-mNeon
    

    Use

    Lentiviral

    Tags

    mNeon

    Expression

    Mammalian

    Available Since

    July 24, 2025

    Availability

    Academic Institutions and Nonprofits only

    

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25. pLenti-CMV-MFSD6-Puro

    Plasmid

    #239953

    Purpose

    Lentiviral vector to generate MFSD6 stable expressing cell line under CMV promoter

    Depositor

    Jan Carette

    Article

    Varanese et al Nature. 2025 Mar 25. doi: 10.1038/s41586

    Insert

    MFSD6
    

    Use

    Lentiviral

    Tags

    myc-flag

    Expression

    Mammalian

    Available Since

    July 24, 2025

    Availability

    Academic Institutions and Nonprofits only

    

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26. pLenti-CMV-MFSD8-Puro

    Plasmid

    #239954

    Purpose

    Lentiviral vector to generate MFSD8 stable expressing cell line under CMV promoter

    Depositor

    Jan Carette

    Article

    Varanese et al Nature. 2025 Mar 25. doi: 10.1038/s41586

    Insert

    MFSD8
    

    Use

    Lentiviral

    Tags

    myc-flag

    Expression

    Mammalian

    Available Since

    July 14, 2025

    Availability

    Academic Institutions and Nonprofits only

    

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27. pAAV-CMV-intron-hfCas13d-pA/EF1a-mCherry-WPRE-pa

    Plasmid

    #233034

    Purpose

    To Express HA tagged hfCas13d the CMV promoter. Also encodes a mCherry gene outside of the viral genome

    Depositor

    Jonathan Ploski

    Article

    Back et al Mol Ther Methods Clin Dev. 2025 Aug 20;3

    Insert

    hfCas13d and mCherry
    

    Use

    AAV

    Tags

    mCherry

    Available Since

    March 4, 2025

    Availability

    Academic Institutions and Nonprofits only

    

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28. pMR-A-3-Sasg

    Plasmid

    #214349

    Purpose

    Expresses T7-RNAP, and cloning backbone for sgRNA

    Depositor

    Yongming Wang

    Article

    Qi et al Nat Chem Biol. 2023 Dec 5. doi: 10.1038/

    Insert

    T7-RNAP
    

    Expression

    Bacterial

    Available Since

    Feb. 27, 2025

    Availability

    Academic Institutions and Nonprofits only

    

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29. pGEX6P1-NEDD4L_HECT

    Plasmid

    #187719

    Purpose

    Express GST-tagged NEDD4L HECT domain in bacterial cells

    Depositor

    Sandra Gabelli

    Article

    Wright et al J Biol Chem. 2024 Mar;300(3):105715. doi

    Insert

    NEDD4L residues 594-975 (NEDD4L Human)
    

    Tags

    GST-HRV 3C site

    Expression

    Bacterial

    Mutation

    deletion of residues 1-593

    Available Since

    Oct. 24, 2024

    Availability

    Academic Institutions and Nonprofits only

    

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30. MP6-SlugABEN-738

    Plasmid

    #214348

    Purpose

    Expresses N-terminus of ABE, and untargeted Bacterial Mutagenesis

    Depositor

    Yongming Wang

    Article

    Qi et al Nat Chem Biol. 2023 Dec 5. doi: 10.1038/

    Insert

    dnaQ926 dam seqA emrR ugi CDA1 and N-terminus of ABE
    

    Expression

    Bacterial

    Available Since

    April 5, 2024

    Availability

    Academic Institutions and Nonprofits only

    

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31. pBT120a17-sg-del

    Plasmid

    #214347

    Purpose

    Expresses pIII

    Depositor

    Yongming Wang

    Article

    Qi et al Nat Chem Biol. 2023 Dec 5. doi: 10.1038/

    Insert

    gIII-xLuxAB
    

    Expression

    Bacterial

    Available Since

    Feb. 29, 2024

    Availability

    Academic Institutions and Nonprofits only

    

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32. mU6-CR1-CRISPRiv2_hU6-CR3-NT-ctrl-guide_EF1a-PuroR-T2A-BFP

    Pooled Library

    #197348

    Purpose

    To allow for genome-wide genetic modifier screening, the library has a second fixed non-targeting control guide.

    Depositor

    Jonathan Weissman, Rebecca Voorhees

    Article

    Guna et al BMC Genomics. 2023 Oct 30;24(1):651. doi

    Species

    Homo sapiens

    Use

    Lentiviral

    Available Since

    May 25, 2023

    Availability

    Academic Institutions and Nonprofits only

33. pD649-HAsp-DLL4-COMP5AP-AviTag-9xHis

    Plasmid

    #157453

    Purpose

    Mammalian expression of cell-surface protein extracellular domain fused to COMP5AP-AviTag-9xHis. Protein is secreted from cells.

    Depositor

    Chris Garcia

    Article

    Wojtowicz et al Cell. 2020 Aug 20;182(4):1027-1043.e17.

    Insert

    DLL4 (DLL4 Human)
    

    Tags

    COMP5AP-AviTag-9xHis

    Expression

    Mammalian

    Promoter

    CMV/SP6

    Available Since

    March 8, 2023

    Availability

    Academic Institutions and Nonprofits only

    

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34. pAAV-CMV-intron-hfCas13d-pA

    Plasmid

    #195864

    Purpose

    To express hfCas13d

    Depositor

    Jonathan Ploski

    Article

    Back et al Mol Ther Methods Clin Dev. 2025 Aug 20;3

    Insert

    high fidelity (hf) version of CasRx (hfCas13d)
    

    Use

    AAV

    Mutation

    Yes: GTGGAATACATTACCAACGTGGTGTACGTG

    Promoter

    CMV

    Available Since

    Jan. 30, 2023

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

35. pAAV-CaMKIIa-hM3D(Gq)-mCherry-WPRE-pA(Short)

    Plasmid

    #183705

    Purpose

    AAV to express hM3D(Gq)-mCherry fusion protein. Viral genome 3' UTR modified to bring the viral genome below the optimal AAV packaging limit

    Depositor

    Jonathan Ploski

    Insert

    hM3D(Gq)
    

    Use

    AAV

    Tags

    mCherry

    Promoter

    CaMKIIa

    Available Since

    May 3, 2022

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

36. pLVTFrep4-creb

    Plasmid

    #182057

    Purpose

    Plasmids for production of LV-based TFactivity reporter

    Depositor

    Kentaro Abe

    Article

    Abe et al iScience. 2022 Feb 14;25(3):103927. doi:

    Insert

    Rep4 and Ref4
    

    Use

    Lentiviral

    Promoter

    synthetic minimal promoter

    Available Since

    March 24, 2022

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

37. FR_GFP

    Plasmid

    #31302

    Depositor

    Gerhart Ryffel

    Article

    Erdmann et al Biol Chem. 2007 Jan . 388(1):91-106.

    Insert

    green fluorescent protein
    

    Expression

    Mammalian

    Available Since

    Oct. 28, 2011

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

38. miReporter-PGK

    Plasmid

    #82477

    Purpose

    microRNA reporter relying on a bidirectional PGK promoter. Contains MCS downstream of H2B-mCherry and H2B-Citrine to insert miRNA binding sites. Contains a Hygromycin selection cassette.

    Depositor

    Pierre Neveu

    Article

    Sladitschek et al PLoS One. 2016 May 6;11(5):e0155177. doi

    Insert

    H2B-mCherry and H2B-Citrine. HygroR
    

    Available Since

    Sept. 16, 2016

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

39. pTubulin-miRFP670nano3

    Plasmid

    #184666

    Purpose

    Human alpha-tubulin labelled with near-infrared fluorescent protein miRFP670nano3

    Depositor

    Vladislav Verkhusha

    Article

    Oliinyk et al Nat Methods. 2022 May 23. pii: 10.1038/s

    Insert

    miRFP670nano3-human alpha-tubulin
    

    Tags

    miRFP670nano3

    Expression

    Mammalian

    Promoter

    CMV

    Available Since

    June 23, 2022

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

40. pGD-p19

    Plasmid

    #196326

    Purpose

    35S promoter-driven expression of the tomato bushy stunt virus p19 RNA silencing suppressor

    Depositor

    Zhenghe Li

    Article

    Ganesan et al J Virol. 2013 Oct;87(19):10598-611. doi:

    Insert

    tomato bushy stunt virus p19
    

    Expression

    Plant

    Promoter

    duplicated cauliflower mosaic virus 35S promoter

    Available Since

    May 3, 2023

    Availability

    Academic Institutions and Nonprofits only

    

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