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Showing: 401 - 450 of 6475 results

  1. pAAV-STAT-CA

    Plasmid
    #195576
    Purpose
    Expresses STAT3 constitutively active mutant
    Depositor
    Kevin Park
    Article
    Luo et al Cell Rep. 2016 Apr 12;15(2):398-410. doi
    Insert
    Signal transducer and activator of transcription 3 (Stat3 Mouse)
    Use
    AAV
    Tags
    Expression
    Mammalian
    Mutation
    changed Alanine 662 to Cysteine and Asparagine 66…
    Promoter
    CMV enhancer and promoter
    Available since
    Feb. 3, 2023
    Availability
    Academic Institutions and Nonprofits only
    195576-plasmid-map-sequence-id-383906

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  3. pAAV.hSynapsin.SF-iGluSnFR.S72A

    Plasmid
    #106176
    Purpose
    Weak affinity glutamate sensor ** A newer version of this sensor is available. Please see iGluSnFR3 plasmids at https://www.addgene.org/browse/article/28220233/ **
    Depositor
    Loren Looger
    Article
    Marvin et al Nat Methods. 2018 Nov;15(11):936-939. do
    Has Service
    AAV1
    Insert
    SF-iGluSnFR.S72A
    Use
    AAV
    Tags
    Expression
    Mutation
    GltI: S72A
    Promoter
    hSynapsin
    Available since
    June 19, 2018
    Availability
    Academic Institutions and Nonprofits only
    106176-plasmid-map-sequence-id-213318

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  4. AAV_CWSL.hSyn.DIO.Synaptophysin-GCaMP6s.P2A.mRuby3

    Plasmid
    #107737
    Purpose
    In the presence of Cre, drives neuron-specific expression of both GCaMP6s fused to the presynaptic protein synaptophysin and independently the red-fluorescent protein mRuby3.
    Depositor
    Rylan Larsen
    Insert
    synaptophysin-GCaMP6s, mRuby3
    Use
    AAV and Cre/Lox
    Tags
    Expression
    Mammalian
    Mutation
    Promoter
    hSyn
    Available since
    March 29, 2018
    Availability
    Academic Institutions and Nonprofits only
    107737-plasmid-map-sequence-id-207281

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  7. AAV-short_BrokenHeart (no BC)

    Plasmid
    #86950
    Purpose
    AAV transfer plasmid containing the BrokenHeart construct: a hyperpiggybac donor transposon interrupting the tdTomato fluorophore. Transposase activity rescues coding sequence.
    Depositor
    Rob Mitra, Joseph Dougherty
    Article
    Cammack et al Proc Natl Acad Sci U S A. 2020 May 5;117
    Insert
    Brokenheart construct
    Use
    AAV
    Tags
    Expression
    Mammalian
    Mutation
    Promoter
    Available since
    April 13, 2020
    Availability
    Academic Institutions and Nonprofits only
    86950-plasmid-map-sequence-id-172437

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  10. pAAV.TBG.PI.LacZ .bGH

    Plasmid
    #105534
    Purpose
    AAV expression of LacZ from TBG promoter
    Depositor
    James M. Wilson
    Insert
    LacZ
    Use
    AAV
    Tags
    Expression
    Mammalian
    Mutation
    Promoter
    TBG
    Available since
    Feb. 2, 2018
    Availability
    Academic Institutions and Nonprofits only
    105534-plasmid-map-sequence-id-202368

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  19. AAVS1-SAGFP

    Plasmid
    #127100
    Purpose
    SA-GFP substrate (Addgene #41594) flanked by human AAVS1 homology arms. Endogenous AAVS1 promoter drives T2A-hygromycin expression after integration. SA-GFP cassette contains PGK-puromycin.
    Depositor
    Adam Karpf
    Insert
    SA-GFP reporter
    Use
    Tags
    Expression
    Mammalian
    Mutation
    Promoter
    Available since
    June 24, 2019
    Availability
    Academic Institutions and Nonprofits only
    127100-plasmid-map-sequence-id-247555

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  30. pCMV-AAV2cap

    Plasmid
    #198014
    Purpose
    For high-level expression of the AAV2 cap gene, suitable for use with pCMV-Rep78/68 SSM library
    Depositor
    George Church
    Article
    Jain et al bioRxiv 2023.01.31.526541
    Insert
    AAV2 cap
    Use
    AAV
    Tags
    Expression
    Mammalian
    Mutation
    WT
    Promoter
    CMV
    Available since
    May 4, 2023
    Availability
    Academic Institutions and Nonprofits only
    198014-plasmid-map-sequence-id-390030

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  36. pAAV.CAG.iAChSnFR-NULL

    Plasmid
    #137956
    Purpose
    Expresses iAChSnFR (non-binding variant) under CAG promoter
    Depositor
    Loren Looger
    Article
    Borden et al bioRxiv 2020
    Insert
    iAChSnFR (non-binding variant)
    Use
    AAV
    Tags
    Expression
    Mammalian
    Mutation
    Y140A binding site mutant
    Promoter
    CAG
    Available since
    Feb. 11, 2020
    Availability
    Academic Institutions and Nonprofits only
    137956-plasmid-map-sequence-id-271715

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  37. pAAV_Efla_FLEX_APEX2-eGFPf

    Plasmid
    #171939
    Purpose
    Expresses a membrane targeted (farnesylation) APEX2-eGFP fusion protein
    Depositor
    David Berson
    Insert
    APEX2-eGFPf
    Use
    AAV and Cre/Lox
    Tags
    Expression
    Mammalian
    Mutation
    Promoter
    Ef1a
    Available since
    July 29, 2021
    Availability
    Academic Institutions and Nonprofits only
    171939-plasmid-map-sequence-id-338504

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  39. pAAV.CMV.PI-si-HBV

    Plasmid
    #187859
    Purpose
    a human siRNA-expressing plasmid targeting HBV
    Depositor
    Yan Zeng
    Insert
    si-HBV
    Use
    AAV
    Tags
    Expression
    Mutation
    Promoter
    Available since
    Aug. 22, 2022
    Availability
    Academic Institutions and Nonprofits only
    187859-plasmid-map-sequence-id-370035

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  42. pX458-AAVS1-sg

    Plasmid
    #194721
    Purpose
    px458 with guide RNA that target hAAVS1
    Depositor
    Rudolf Jaenisch
    Article
    Haiting et al bioRxiv
    Insert
    Cas9 (AAVS1 Streptococcus pyogenes)
    Use
    CRISPR
    Tags
    Expression
    Mammalian
    Mutation
    Promoter
    Available since
    Jan. 10, 2023
    Availability
    Academic Institutions and Nonprofits only
    194721-plasmid-map-sequence-id-381227

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  43. pAAV_LP1B_St1Cas9_LMD-9_SpA_U6_sgRNA

    Plasmid
    #110624
    Purpose
    A single vector AAV-Cas9 system containing a liver-specific promoter with Cas9 from Streptococcus thermophilus CRISPR1 (St1Cas9 LMD-9) and its U6-driven sgRNA
    Depositor
    Yannick Doyon
    Article
    Agudelo et al Genome Res. 2020 Jan;30(1):107-117. doi:
    Inserts
    St1Cas9 LMD-9
    sgRNA for St1Cas9
    Use
    AAV, CRISPR, and Mouse Targeting
    Tags
    SV40 NLS
    Expression
    Mammalian
    Mutation
    Promoter
    LP1B and hU6
    Available since
    May 25, 2018
    Availability
    Academic Institutions and Nonprofits only
    110624-plasmid-map-sequence-id-211314

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  46. CAP-AAV.FUS.3

    Plasmid
    #222333
    Purpose
    AAV.FUS.3 Rep-Cap plasmid for production of AAV.FUS.3, a capsid with tropism for CNS neurons upon focused ultrasound mediated delivery.
    Depositor
    Jerzy Szablowski, Mikhail Shapiro
    Article
    Li et al Nat Commun. 2024 Jun 10;15(1):4924. doi:
    Insert
    AAV9 modified with 7-amino acid insertion between AA position 588 and 589 of VP1
    Use
    AAV
    Tags
    Expression
    Mutation
    Promoter
    p41
    Available since
    Aug. 8, 2024
    Availability
    Academic Institutions and Nonprofits only
    222333-plasmid-map-sequence-id-441908

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  49. pXWJ109As(RS-te-AAV)

    Plasmid
    #123156
    Purpose
    For TEV-based leakiness regulation. pSB3K3 carrying J109-30arsR-t-ParsR-30hrpR-30hrpS-t-PhrpLE-30gfp-te-AAV-t
    Depositor
    Baojun Wang
    Article
    Wan et al Nat Chem Biol. 2019 May;15(5):540-548. d
    Insert
    J109-30arsR-t-ParsR-30hrpR-30hrpS-t-PhrpLE-30gfp-te-AAV-t
    Use
    Synthetic Biology
    Tags
    Expression
    Bacterial
    Mutation
    Promoter
    J109, ParsR, PhrpLE
    Available since
    May 9, 2019
    Availability
    Academic Institutions and Nonprofits only
    123156-plasmid-map-sequence-id-240600

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Showing: 401 - 450 of 6475 results