We narrowed to 67,891 results for: TOR

1. MKC176_EPOR(2A-synEPOR)

   Plasmid

   #232414

   Purpose

   AAV production plasmid for EPOR(synEPOR) vector from Figs. 3-5 that mediates HDR at EPOR locus using EPOR gRNA. synEPOR is codon diverged to prevent premature recombination with EPOR locus.

   Depositor

   Kyle Cromer

   Article

   Shah et al bioRxiv 2024.04.12.589260

   Insert

   Truncated Erythropoietin Receptor (EPOR Human)
   

   Use

   AAV

   Expression

   Mammalian

   Available Since

   Feb. 27, 2025

   Availability

   Academic Institutions and Nonprofits only

   

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2. pLentiCRISPR-v1-sgABCC4_1

   Plasmid

   #217433

   Purpose

   Lentiviral vector expressing Cas9 and an sgRNA targeting human ABCC4

   Depositor

   Jason Cantor

   Article

   Flickinger et al Sci Adv. 2024 Oct 4;10(40):eadq3591. doi

   Insert

   sgRNA 1 targeting ABCC4 (ABCC4 Human)
   

   Use

   CRISPR and Lentiviral

   Expression

   Mammalian

   Promoter

   U6

   Available Since

   Jan. 31, 2025

   Availability

   Academic Institutions and Nonprofits only

   

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3. pLentiCRISPR-v1-sgABCC4_3

   Plasmid

   #217434

   Purpose

   Lentiviral vector expressing Cas9 and an sgRNA targeting human ABCC4

   Depositor

   Jason Cantor

   Article

   Flickinger et al Sci Adv. 2024 Oct 4;10(40):eadq3591. doi

   Insert

   sgRNA 3 targeting ABCC4 (ABCC4 Human)
   

   Use

   CRISPR and Lentiviral

   Expression

   Mammalian

   Promoter

   U6

   Available Since

   Jan. 31, 2025

   Availability

   Academic Institutions and Nonprofits only

   

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4. pT5_TRE-ARID1A-FLAG_PGK-H2B-RFP

   Plasmid

   #203965

   Purpose

   Dox inducible FLAG tag ARID1a in a sleeping beauty transposon construct

   Depositor

   Elaine Fuchs

   Article

   Yang et al Nat Cell Biol. 2023 Jul 24. doi: 10.1038

   Insert

   ARID1A (Arid1a Mouse)
   

   Use

   Sleeping beauty transposon

   Tags

   FLAG

   Expression

   Mammalian

   Promoter

   TRE

   Available Since

   Jan. 16, 2025

   Availability

   Academic Institutions and Nonprofits only

   

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5. pCAG_SRGAP2A_SH3(W765A)_GFP

   Plasmid

   #222616

   Purpose

   Expresses a form of full length SRGAP2 with one point mutation (W765A) in the SH3 domain abrogating its ability to bind to Gephyrin.

   Depositor

   Franck Polleux

   Article

   Fossati et al Neuron. 2016 Jul 20;91(2):356-69. doi: 1

   Insert

   SRGAP2 (SRGAP2 Human)
   

   Tags

   EGFP

   Expression

   Mammalian

   Mutation

   Point mutation W765A (SH3 domain)

   Available Since

   Oct. 9, 2024

   Availability

   Academic Institutions and Nonprofits only

   

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6. pCAG_SRGAP2A_SH3(W765A)_HA

   Plasmid

   #222614

   Purpose

   Expresses a form of full length SRGAP2 with one point mutation (W765A) in the SH3 domain abrogating its ability to bind to Gephyrin.

   Depositor

   Franck Polleux

   Article

   Fossati et al Neuron. 2016 Jul 20;91(2):356-69. doi: 1

   Insert

   SRGAP2 (SRGAP2 Human)
   

   Tags

   HA

   Expression

   Mammalian

   Mutation

   Point mutation W765A (SH3 domain)

   Available Since

   Oct. 9, 2024

   Availability

   Academic Institutions and Nonprofits only

   

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7. pCAG SRGAP2A_EVH1(P339L F342C)

   Plasmid

   #222613

   Purpose

   Expresses a form of full length SRGAP2 with two point mutations (P339L and F342C) that abrogate EVH1 binding site for Homer1

   Depositor

   Franck Polleux

   Article

   Fossati et al Neuron. 2016 Jul 20;91(2):356-69. doi: 1

   Insert

   SRGAP2 (SRGAP2 Human)
   

   Tags

   EGFP

   Expression

   Mammalian

   Mutation

   Point mutations P339L and F342C

   Available Since

   Oct. 9, 2024

   Availability

   Academic Institutions and Nonprofits only

   

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8. pBK1301-AAV-EFSNC-dCjCas9-NIPP1(143-224)

   Plasmid

   #223146

   Purpose

   Expression of truncated NIPP1 with dCjCas9 and empty gRNA scaffold

   Depositor

   Boris Kantor

   Article

   Kantor et al bioRxiv [Preprint]. 2024 May 19:2023.04.

   Insert

   NIPP1 (PPP1R8 Human)
   

   Use

   AAV and CRISPR

   Tags

   3xFLAG

   Expression

   Mammalian

   Mutation

   Encodes aa 143-224

   Promoter

   EF1a

   Available Since

   Aug. 28, 2024

   Availability

   Academic Institutions and Nonprofits only

   

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9. pBK1300-AAV-EFSNC-dCjCas9-MBD2(176-231)

   Plasmid

   #223145

   Purpose

   Expression of truncated MBD2 with dCjCas9 and empty gRNA scaffold

   Depositor

   Boris Kantor

   Article

   Kantor et al bioRxiv [Preprint]. 2024 May 19:2023.04.

   Insert

   MBD2 (MBD2 Human)
   

   Use

   AAV and CRISPR

   Tags

   3xFLAG

   Expression

   Mammalian

   Mutation

   Encodes aa 176-231

   Promoter

   EF1a

   Available Since

   Aug. 23, 2024

   Availability

   Academic Institutions and Nonprofits only

   

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10. pBK1311-AAV-EFSNC-dSaCas9-NIPP1(143-224)

    Plasmid

    #223156

    Purpose

    Expression of truncated NIPP1 with dSaCas9 and empty gRNA scaffold

    Depositor

    Boris Kantor

    Article

    Kantor et al bioRxiv [Preprint]. 2024 May 19:2023.04.

    Insert

    NIPP1 (PPP1R8 Human)
    

    Use

    AAV and CRISPR

    Tags

    3xFLAG

    Expression

    Mammalian

    Mutation

    Encodes aa 143-224

    Promoter

    EF1a

    Available Since

    Aug. 22, 2024

    Availability

    Academic Institutions and Nonprofits only

    

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11. pBK1310-AAV-EFSNC-dSaCas9-MBD2(176-231)

    Plasmid

    #223155

    Purpose

    Expression of truncated MBD2 with dSaCas9 and empty gRNA scaffold

    Depositor

    Boris Kantor

    Article

    Kantor et al bioRxiv [Preprint]. 2024 May 19:2023.04.

    Insert

    MBD2 (MBD2 Human)
    

    Use

    AAV and CRISPR

    Tags

    3xFLAG

    Expression

    Mammalian

    Mutation

    Encodes aa 176-231

    Promoter

    EF1a

    Available Since

    Aug. 22, 2024

    Availability

    Academic Institutions and Nonprofits only

    

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12. pX330_DAZL_cterm2

    Plasmid

    #222919

    Purpose

    Cas9/sgRNA plasmid for targeting DAZL

    Depositor

    George Church

    Article

    Pierson Smela et al bioRxiv 2022.07.11.499564

    Insert

    Cas9, DAZL sgRNA 2 (DAZL Human, Synthetic)
    

    Use

    CRISPR

    Available Since

    Aug. 1, 2024

    Availability

    Academic Institutions and Nonprofits only

    

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13. pX330_DAZL_cterm3

    Plasmid

    #222920

    Purpose

    Cas9/sgRNA plasmid for targeting DAZL

    Depositor

    George Church

    Article

    Pierson Smela et al bioRxiv 2022.07.11.499564

    Insert

    Cas9, DAZL sgRNA 3 (DAZL Human, Synthetic)
    

    Use

    CRISPR

    Available Since

    Aug. 1, 2024

    Availability

    Academic Institutions and Nonprofits only

    

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14. pX330_TFAP2C_cterm

    Plasmid

    #222916

    Purpose

    Cas9/sgRNA plasmid for targeting TFAP2C

    Depositor

    George Church

    Article

    Pierson Smela et al bioRxiv 2022.07.11.499564

    Insert

    Cas9, TFAP2C sgRNA (TFAP2C Human, Synthetic)
    

    Use

    CRISPR

    Available Since

    Aug. 1, 2024

    Availability

    Academic Institutions and Nonprofits only

    

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15. pX330_FIGLA_cterm4

    Plasmid

    #222909

    Purpose

    Cas9/sgRNA plasmid for targeting FIGLA

    Depositor

    George Church

    Article

    Pierson Smela et al bioRxiv 2022.07.11.499564

    Insert

    Cas9, FIGLA sgRNA 4 (FIGLA Human, Synthetic)
    

    Use

    CRISPR

    Available Since

    July 22, 2024

    Availability

    Academic Institutions and Nonprofits only

    

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16. pX330_FIGLA_cterm3

    Plasmid

    #222908

    Purpose

    Cas9/sgRNA plasmid for targeting FIGLA

    Depositor

    George Church

    Article

    Pierson Smela et al bioRxiv 2022.07.11.499564

    Insert

    Cas9, FIGLA sgRNA 3 (FIGLA Human, Synthetic)
    

    Use

    CRISPR

    Available Since

    July 22, 2024

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

17. pX330_FIGLA_cterm2

    Plasmid

    #222907

    Purpose

    Cas9/sgRNA plasmid for targeting FIGLA

    Depositor

    George Church

    Article

    Pierson Smela et al bioRxiv 2022.07.11.499564

    Insert

    Cas9, FIGLA sgRNA 2 (FIGLA Human, Synthetic)
    

    Use

    CRISPR

    Available Since

    July 22, 2024

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

18. pX330_FIGLA_cterm1

    Plasmid

    #222906

    Purpose

    Cas9/sgRNA plasmid for targeting FIGLA

    Depositor

    George Church

    Article

    Pierson Smela et al bioRxiv 2022.07.11.499564

    Insert

    Cas9, FIGLA sgRNA 1 (FIGLA Human, Synthetic)
    

    Use

    CRISPR

    Available Since

    July 22, 2024

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

19. pX330_NANOS3_cterm

    Plasmid

    #222904

    Purpose

    Cas9/sgRNA plasmid for targeting NANOS3

    Depositor

    George Church

    Article

    Pierson Smela et al bioRxiv 2022.07.11.499564

    Insert

    Cas9, NANOS3 sgRNA (NANOS3 Human, Synthetic)
    

    Use

    CRISPR

    Available Since

    July 22, 2024

    Availability

    Academic Institutions and Nonprofits only

    

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20. pPB-cT3G-cERP2-FIGLA

    Plasmid

    #222929

    Purpose

    PiggyBac transposon plasmid for doxycycline inducible expression of FIGLA

    Depositor

    George Church

    Article

    Pierson Smela et al bioRxiv 2022.07.11.499564

    Insert

    FIGLA (FIGLA Human)
    

    Expression

    Mammalian

    Available Since

    July 22, 2024

    Availability

    Academic Institutions and Nonprofits only

    

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21. pPB-cT3G-cERP2-DLX5

    Plasmid

    #222927

    Purpose

    PiggyBac transposon plasmid for doxycycline inducible expression of DLX5

    Depositor

    George Church

    Article

    Pierson Smela et al bioRxiv 2022.07.11.499564

    Insert

    DLX5 (DLX5 Human)
    

    Expression

    Mammalian

    Available Since

    July 19, 2024

    Availability

    Academic Institutions and Nonprofits only

    

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22. pPB-cT3G-cERH-LHX8

    Plasmid

    #222921

    Purpose

    PiggyBac transposon plasmid for doxycycline inducible expression of LHX8

    Depositor

    George Church

    Article

    Pierson Smela et al bioRxiv 2022.07.11.499564

    Insert

    LHX8 (LHX8 Human)
    

    Expression

    Mammalian

    Available Since

    July 18, 2024

    Availability

    Academic Institutions and Nonprofits only

    

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23. pWR63(YUM1)

    Plasmid

    #203336

    Purpose

    episomal Cas9 and YUM1-targeting sgRNA expression vector for S. stipitis

    Depositor

    J. Brian Robertson

    Article

    Reichard et al mSphere. 2023 Aug 24;8(4):e0022423. doi:

    Inserts

    TEF1 promoter (S. stipitis) (TEF1 S. stipitis (yeast))
    coHPH
    ACT1 terminator (S. stipitis)
    CCW12 promoter (S. stipitis)
    CaCas9
    ADH2 terminator (S. stipitis)
    ARS from S. stipitis chromosome 1
    THD3 promoter (S. stipitis)
    tRNA-sgRNA(SapI)-HDV
    ADH1 terminator (S. stipitis)
    YUM1-targeting sequence
    

    Use

    CRISPR

    Expression

    Yeast

    Available Since

    June 25, 2024

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

24. pWR63

    Plasmid

    #203331

    Purpose

    episomal Cas9 and sgRNA expression vector without sgRNA for S. stipitis

    Depositor

    J. Brian Robertson

    Article

    Reichard et al mSphere. 2023 Aug 24;8(4):e0022423. doi:

    Inserts

    TEF1 promoter (S. stipitis) (TEF1 S. stipitis (yeast))
    coHPH
    ACT1 terminator (S. stipitis)
    CCW12 promoter (S. stipitis)
    CaCas9
    ADH2 terminator (S. stipitis)
    ARS from S. stipitis chromosome 1
    THD3 promoter (S. stipitis)
    tRNA-sgRNA(SapI)-HDV
    ADH1 terminator (S. stipitis)
    

    Use

    CRISPR

    Expression

    Yeast

    Available Since

    June 25, 2024

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

25. pFlare9A-Clip2E9 WT

    Plasmid

    #209574

    Purpose

    minigene construct for Clip2 E9 alternative splicing

    Depositor

    Sika Zheng

    Article

    Zhang et al Neuron. 2019 Feb 20;101(4):690-706.e10.

    Insert

    Clip2 (Clip2 Mouse)
    

    Expression

    Mammalian

    Promoter

    CMV

    Available Since

    March 7, 2024

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

26. pEGFP-C1-deltaExon15-III

    Plasmid

    #209567

    Purpose

    Mammalian expression of Shtn1 long isoform with E15 deletion III

    Depositor

    Sika Zheng

    Article

    Zhang et al Neuron. 2019 Feb 20;101(4):690-706.e10.

    Insert

    Shtn1 long isoform with E15 deletion III (4930506M07Rik Mouse)
    

    Expression

    Mammalian

    Mutation

    Exon15 deletion III

    Available Since

    March 5, 2024

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

27. pCAGGS-AnkG ZU5in-3xHA

    Plasmid

    #213730

    Purpose

    Mammalian cell expression vector for overexpression of AnkG ZU5in isoform in motor neurons.

    Depositor

    Chaolin Zhang

    Article

    Jacko et al Neuron. 2018 Feb 21;97(4):853-868.e6. do

    Insert

    AnkG ZU5in (Ank3 Mouse)
    

    Expression

    Mammalian

    Available Since

    March 4, 2024

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

28. pCAGGS-AnkB ZU5ex-3xHA

    Plasmid

    #213732

    Purpose

    Mammalian cell expression vector for overexpression of AnkB ZU5ex isoform in motor neurons.

    Depositor

    Chaolin Zhang

    Article

    Jacko et al Neuron. 2018 Feb 21;97(4):853-868.e6. do

    Insert

    AnkB ZU5ex (Ank2 Mouse)
    

    Expression

    Mammalian

    Available Since

    Feb. 12, 2024

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

29. pCAGGS-AnkG ZU5ex-3xHA

    Plasmid

    #213731

    Purpose

    Mammalian cell expression vector for overexpression of AnkG ZU5ex isoform in motor neurons.

    Depositor

    Chaolin Zhang

    Article

    Jacko et al Neuron. 2018 Feb 21;97(4):853-868.e6. do

    Insert

    AnkG ZU5ex (Ank3 Mouse)
    

    Expression

    Mammalian

    Available Since

    Feb. 12, 2024

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

30. pVITRO1-HAPPID1

    Plasmid

    #204626

    Purpose

    Expresses the human anti-Phl p 7 IgD/λ antibody 102.1F10 (HAPPID1) in mammalian cells. HAPPID1 binds to the grass pollen allergen Phl p 7 with subnanomolar affinity.

    Depositor

    James McDonnell

    Article

    Vester et al Antibodies (Basel). 2023 Nov 16;12(4):75

    Inserts

    HAPPID1 heavy chain
    HAPPID1 light chain
    

    Expression

    Mammalian

    Promoter

    mouse elongation factor 1 alpha and rat elongatio…

    Available Since

    Nov. 29, 2023

    Availability

    Academic Institutions and Nonprofits only

    

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