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Plasmid#139655PurposeEndogenous tagging of GluA1: C-terminal (amino acid position: STOP codon)DepositorInsertgRNA and HaloTag donor
UseAAVTagsExpressionMammalianMutationPromoterU6Available sinceJune 8, 2020AvailabilityAcademic Institutions and Nonprofits only -
pAAV-G12-mTGFB1
Plasmid#219553PurposemTGFB1 expression in mammlian cells. pAAV vector. Reporter plasmid.DepositorInsertmTGFB1 (Tgfb1 Mouse)
UseAAVTagsExpressionMammalianMutationPromoter12xUAS with TATA-box minimal promoterAvailable sinceMay 23, 2024AvailabilityAcademic Institutions and Nonprofits only -
pAAV-hSyn-iPASnFR-L
Plasmid#225236PurposeAAV expression of iPASnFR-L from hSyn promoterDepositorInsertiPASnFR-L
UseAAVTagsExpressionMutationPromoterAvailable sinceSept. 16, 2024AvailabilityAcademic Institutions and Nonprofits only -
pAAV-CaMKII-JEDI-1P-WPRE
Plasmid#202615PurposeGenetically encoded voltage indicator (GEVI) JEDI-1P in AAV production vector for expression in excitatory glutamatergic neurons using the promoter CaMKIIDepositorInsertJEDI-1P
UseAAVTagsExpressionMammalianMutationPromoterCaMKIIaAvailable sinceJune 22, 2023AvailabilityAcademic Institutions and Nonprofits only -
pAAV-CAG-SomaGCaMP6f2
Plasmid#158757PurposeCell body-targeted GCaMP6f, under CAG promoter: GCaMP6f followed by a linker, and the EE-RR coiled coil motif (GCaMP6f-27-EE-RR). As bright as conventional GCaMP6f.DepositorHas ServiceAAV8 and AAV9InsertSomaGCaMP6f2
UseAAVTagsExpressionMammalianMutationPromoterCAG promoterAvailable sinceSept. 10, 2020AvailabilityAcademic Institutions and Nonprofits only -
pAAV-beta-arrestin2-HA-TEV219
Plasmid#104845Purposeb2AR-SPARK protease componentDepositorInsertbeta-arrestin2-HA-TEV219
UseAAVTagsExpressionMammalianMutationPromoterCMVAvailable sinceJan. 6, 2018AvailabilityAcademic Institutions and Nonprofits only -
AAV-EFS-LSL-nlsGFP-shRNA
Plasmid#175584PurposeConditional express shRNA with control of LoxPDepositorTypeEmpty backboneUseAAV and Cre/LoxTagsExpressionMammalianMutationPromoterEFSAvailable sinceSept. 24, 2021AvailabilityAcademic Institutions and Nonprofits only -
AAV-actin prom-dsRed-adra2a.1227.shRNA
Plasmid#67880Purposeexpresses dsRed and shRNA to knock down adra2a receptorsDepositorInsertdsRed and shRNA to knock down the mouse adra2 receptor
UseAAVTagsExpressionMammalianMutationPromoterchicken beta actinAvailable sinceSept. 11, 2015AvailabilityAcademic Institutions and Nonprofits only -
pAAV-hSyn-GRAB_CRFmut
Plasmid#208659PurposeExpresses the genetically-encoded fluorescent corticotropin-releasing factor (CRF) control sensor GRAB_CRFmut in neuronsDepositorInsertGPCR activation based corticotropin-releasing factor (CRF) contorl sensor GRAB_CRFmut
UseAAVTagsExpressionMutationPromoterhSynAvailable sinceOct. 13, 2023AvailabilityAcademic Institutions and Nonprofits only -
pAAV-hSyn-hPOMC1-26-sbGLuc-P2A-dTomato
Plasmid#176704Purposeneural activity dependent release of sbGLuc from presynaptic vesiclesDepositorInsertsGaussia luciferase, slow burn
dTomato
UseAAVTagsP2A and hPOMC1-26ExpressionMutationPromoterhSynAvailable sinceNov. 9, 2021AvailabilityAcademic Institutions and Nonprofits only -
pAAV-Ef1a-DIO hChR2(C128S/D156A)-mCherry
Plasmid#35504PurposeAAV expression of Ef1a-driven, cre-dependent, stabilized step function opsin (SSFO) for optogenetic activation.DepositorInserthChR2(C128S/D156A)-mCherry
UseAAVTagsmCherryExpressionMammalianMutationC128S and D156APromoterEf1aAvailable sinceApril 18, 2012AvailabilityAcademic Institutions and Nonprofits only -
pAAV-Syn-VARNAM2
Plasmid#195520PurposeRed fluorescent, negative response-polarity voltage indicator under the control of synapsin promoterDepositorInsertVARNAM2
UseAAVTagsExpressionMammalianMutationVARNAM SI linkerPromoterSynapsinAvailable sinceJan. 30, 2023AvailabilityAcademic Institutions and Nonprofits only -
pAAV-TRE-FLEX-ChR2-YFP
Plasmid#110337PurposeChR2-YFP reporter vector of iTango and Cal-Light system for AAV productionDepositorInserttetO-Flex-ChR2-YFP
UseAAVTagsExpressionMammalianMutationChr2 H134RPromotertetOAvailable sinceMay 22, 2018AvailabilityAcademic Institutions and Nonprofits only -
Luciferase shRNA
Plasmid#225343PurposeshRNAmir backbone for RNA interference, with YFPDepositorInsertLuciferase shRNA (LOC116160065 Mouse)
UseAAV and RNAiTagsExpressionMammalianMutationPromoterCBAAvailable sinceSept. 11, 2024AvailabilityAcademic Institutions and Nonprofits only -
pAAV-cTNT-Cre-miR122 TS
Plasmid#209784PurposeExpresses Cre by the specific cTNT promoter and incorporation of the miR122 target sequences (miR122TS) into the 3’ untranslated region (3’ UTR)DepositorInsertmiR122 ts
UseAAVTagsExpressionMutationPromotercTNTAvailable sinceMay 29, 2024AvailabilityAcademic Institutions and Nonprofits only -
AAV-hSyn-dSaCas9-NLS-3xHA-3xSunTag_bGHpA
Plasmid#177345PurposeAAV expression of a catalytically inactive SaCas9 (dSaCas9) fused with three copies of SunTag sequence from Synapsin promoterDepositorInsertdead hSaCas9
UseAAV and CRISPRTags3x GCN4 peptide, 3xHA, and NLSExpressionMammalianMutationD10A, N580APromoterSynapsinAvailable sinceSept. 5, 2024AvailabilityAcademic Institutions and Nonprofits only -
pAAV-FLEX-hKCNQ3(R230C)-P2A-EGFP
Plasmid#209194PurposeCre-dependent expression of Kcnq3 with R230C mutation and GFP from the same transcriptDepositorInsertKcnq3 (KCNQ3 Human)
UseAAVTagsFLAGExpressionMammalianMutationR230 to C230PromoterCMVAvailable sinceJan. 3, 2024AvailabilityAcademic Institutions and Nonprofits only -
pAAV-TRE-DIO-ChR2-TdTomato (Cre-OFF)
Plasmid#166610PurposeEncodes Cre-inactivated ChR2-TdTomato under control of the TREDepositorInsertChR2-TdTomato
UseAAVTagsExpressionMutationH134RPromotertetracycline response elementAvailable sinceApril 5, 2021AvailabilityAcademic Institutions and Nonprofits only -
pAAV-CAG-miRFP713-P2A-GFP
Plasmid#197163PurposeExpresses the protein of miRFP713-P2A-GFP in mammalian cellsDepositorInsertmiRFP713-P2A-GFP
UseAAVTagsExpressionMutationPromoterAvailable sinceMarch 13, 2023AvailabilityAcademic Institutions and Nonprofits only -
AAV-NG-CBE C
Plasmid#227422Purposeexpresses the C-terminal of AAV-NG-CBEDepositorInsertAAV-NG-CBE C-terminal
UseAAV and CRISPRTagsExpressionMammalianMutationPromoterCbhAvailable sinceDec. 13, 2024AvailabilityAcademic Institutions and Nonprofits only -
AAV-AID-N51A-CBE N
Plasmid#227421Purposeexpresses the N-terminal of AID-N51A-CBEDepositorInsertAAV-AID-N51A-CBE N-terminal (AICDA Human)
UseAAV and CRISPRTagsExpressionMammalianMutationPromoterCbhAvailable sinceOct. 23, 2024AvailabilityAcademic Institutions and Nonprofits only -
AAV-CMV-scFVDnmt3AL_bGHpA
Plasmid#177347PurposeAAV expression of a fusion protein with scFV, catalytic domain of Dnmt3a and C terminal domain of Dnmt3l for targeted DNA methylation editingDepositorInsertcatalytic domain of DNA Methyltransferase 3 Alpha (Dnmt3a Mouse)
UseAAVTagsC-terminal domain of mouse Dnmt3l (194–415 aa), P…ExpressionMammalianMutation598–908 aa of mouse Dnmt3aPromoterCMVAvailable sinceSept. 5, 2024AvailabilityAcademic Institutions and Nonprofits only -
AAV-CMV-scFVtet1_bGHpA
Plasmid#177351PurposeAAV expression of scFV-fused catalytic domain of TET1 for targeted DNA methylation editingDepositorInsertTet Methylcytosine Dioxygenase 1 (TET1 Human)
UseAAVTagsmyc and scFVExpressionMammalianMutationN terminal domain of human Tet1PromoterCMV promoterAvailable sinceSept. 5, 2024AvailabilityAcademic Institutions and Nonprofits only -
pAAV2-hSyn1-NES-ChemoG-CaM
Plasmid#193817PurposeExpression of ChemoG-CaM in primary neuronsDepositorInsertChemoG-CaM
UseAAVTagsExpressionMutationEGFP:A206K; HT7: L271EPromoterhSyn1Available sinceJune 9, 2023AvailabilityAcademic Institutions and Nonprofits only -
pAAV-Ef1a-Con/Foff 2.0-GCaMP6M
Plasmid#137120PurposeIntersectional viral expression of GCaMP6M in cells expressing Cre AND NOT FlpDepositorHas ServiceAAV8InsertCon/Foff 2.0-GCaMP6M
UseAAV, Cre/Lox, and Synthetic Biology ; Flp/frtTagsExpressionMutationRemoved RSET tagPromoterEF1aAvailable sinceJune 25, 2020AvailabilityAcademic Institutions and Nonprofits only -
pAAV-hsyn-flex-Voltron-ST
Plasmid#119036PurposeCre-dependant expression of soma-localized Voltron in neuronsDepositorHas ServiceAAV1InsertVoltron-ST
UseAAV and Cre/LoxTagsExpressionMammalianMutationPromoterhsynAvailable sinceDec. 19, 2018AvailabilityAcademic Institutions and Nonprofits only -
pGP-AAV-syn-jGCaMP7c variant 1513-WPRE
Plasmid#105321PurposeAAV-mediated expression of ultrasensitive protein calcium sensor under the Syn promoterDepositorHas ServiceAAV1InsertjGCaMP7c variant 1513
UseAAVTagsT7 epitope, Xpress tag, 6xHisExpressionMammalianMutationPromoterSynapsinAvailable sinceJan. 23, 2018AvailabilityAcademic Institutions and Nonprofits only -
AAV-GfaABC1D-iCreV-4x6T
Plasmid#196412PurposeAstrocytic expression of light-inducible iCreV recombinase in AAV; astrocyte specificity enhanced with 4x6T miRNA targeting cassetteDepositorInsertiCreV
UseAAV; Astrocyte-selectiveTagsExpressionMammalianMutationPromoterCAG and GfaABC1DAvailable sinceFeb. 21, 2023AvailabilityAcademic Institutions and Nonprofits only -
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AAV-CAG-FLEX-mCherry
Plasmid#178583PurposeCre-dependent expression of mCherry under the constitutive promoterDepositorInsertmCherry
UseAAVTagsExpressionMammalianMutationPromoterAvailable sinceApril 8, 2022AvailabilityAcademic Institutions and Nonprofits only -
pAAV-CAG-FLEX-Archon1-KGC-EGFP-ER2
Plasmid#108422PurposeAAV production plasmid encoding for Archon1 fluorescent voltage reporter, Cre-dependent expressionDepositorHas ServiceAAV5InsertArchon1-KGC-EGFP-ER2
UseAAV and Cre/LoxTagsExpressionMammalianMutationPromoterCAGAvailable sinceJune 6, 2018AvailabilityAcademic Institutions and Nonprofits only -
pAAV.hSyanpsin.(cyto).iATPSnFR2.S29W.A95K.HaloTag
Plasmid#209663PurposeExpression of iATPSnFR2, high affinityDepositorInsertiATPSnFR2.S29W.HaloTag
UseAAVTagsExpressionMutationS29W.A95KPromoterhSynAvailable sinceNov. 6, 2023AvailabilityAcademic Institutions and Nonprofits only -
pAAV-Ef1a-Con/Fon-sRGECO
Plasmid#137126PurposeIntersectional viral expression of sRGECO in cells expressing both Cre AND FlpDepositorHas ServiceAAV8InsertCon/Fon-sRGECO
UseAAV, Cre/Lox, and Synthetic Biology ; Flp/frtTagsExpressionMutationE217DPromoterEF1aAvailable sinceJune 25, 2020AvailabilityAcademic Institutions and Nonprofits only -
JD141
Plasmid#229487PurposeEf1a promoter driving expression of adenoviral L4-22k/33k genesDepositorInsertL4-22k/33k
UseAAV and AdenoviralTagsExpressionMammalianMutationPromoterEf1aAvailable sinceDec. 2, 2024AvailabilityAcademic Institutions and Nonprofits only -
JD94
Plasmid#229479PurposeCMV promoter driving expression of adenoviral E2A geneDepositorInsertE2A
UseAAV and AdenoviralTagsExpressionMammalianMutationPromoterCMVAvailable sinceDec. 2, 2024AvailabilityAcademic Institutions and Nonprofits only -
JD80
Plasmid#229480PurposeAdenoviral VA RNA I geneDepositorInsertVA RNA I
UseAAV and AdenoviralTagsExpressionMammalianMutationPromoterwt promoterAvailable sinceDec. 2, 2024AvailabilityAcademic Institutions and Nonprofits only -
pAAV-CaMKIIa-HA-deLACCO1-NGR
Plasmid#207990PurposeControl biosensor for extracellular L-lactateDepositorInsertdeLACCO1
UseAAVTagsExpressionMutationPromoterCaMKIIAvailable sinceJan. 5, 2024AvailabilityAcademic Institutions and Nonprofits only -
AAV-GFAP(long)-FLEX-GCaMP7f
Plasmid#189612PurposeCre-dependent GCaMP7f under the GFAP promoterDepositorInsertGCaMP7f
UseAAV and Cre/LoxTagsGCaMP7fExpressionMammalianMutationPromoterAvailable sinceSept. 16, 2022AvailabilityAcademic Institutions and Nonprofits only -
pAAV-CAGGS-Flex/3'USS-GFP(ATG mut)
Plasmid#197885PurposeCan be used to generate AAV virus that will express GFP in the presence of Cre and the leakage expression is significantly reduced without CreDepositorInsertGFP
UseAAVTagsExpressionMutationN/APromoterCAGAvailable sinceMarch 15, 2023AvailabilityAcademic Institutions and Nonprofits only -
paavCAG-pre-mGRASP-2A-dTomato
Plasmid#51902Purposepre-2AtoDepositorInsertpresynaptic mGRASP
UseAAV and Cre/LoxTagsExpressionMutationPromoterAvailable sinceJan. 27, 2015AvailabilityAcademic Institutions and Nonprofits only -
AiP1048-pAAV-mscRE10-minBGpromoter-tTA2-WPRE-hGHpA
Plasmid#163481PurposeDirect-expressing tTA2 AAV Virus. Alias: AiP1048 - pAAV-AiE2010m-minBG-tTA2-WPRE-HGHpAInserttTA2
UseAAVTagsExpressionMutationPromoterBeta Globin minimal promoterAvailable sinceFeb. 26, 2021AvailabilityAcademic Institutions and Nonprofits only -
pAAV-CaMKII-Chronos-GFP
Plasmid#58805PurposeAAV expression of Chronos-GFP under the CaMKII promoterDepositorInsertChronos-GFP
UseAAVTagsGFPExpressionMammalianMutationPromoterCaMKIIAvailable sinceAug. 13, 2014AvailabilityAcademic Institutions and Nonprofits only -
pAAV-CAG-FLEX-SomArchon
Plasmid#126943PurposeCre-dependent expression of SomArchon under CAG promoterDepositorInsertSomArchon
UseAAVTagsGFPExpressionMammalianMutationPromoterCAGAvailable sinceSept. 12, 2019AvailabilityAcademic Institutions and Nonprofits only -
aav-tnt-actn2-gfp
Plasmid#165034PurposeAAV-based delivery of ACTN2-GFP into cardiomyocytes in vivoDepositorInsertACTN2 (Actn2 Mouse)
UseAAVTagsGFPExpressionMutationPromotercTNTAvailable sinceMarch 8, 2021AvailabilityAcademic Institutions and Nonprofits only -
pAAV-hSyn-GACh2.0
Plasmid#121921Purposeexpress the genetically-encoded fluorescent acethycholine(ACh) sensor GACh2.0DepositorInsertGPCR activation based ACh sensor GACh2.0
UseAAVTagsExpressionMutationPromoterhSynAvailable sinceFeb. 21, 2019AvailabilityAcademic Institutions and Nonprofits only -
pAAV-Syn-Soma-jGCaMP8f
Plasmid#182943PurposeCell body-targeted jGCaMP8f, under synapsin promoter.DepositorInsertSoma-jGCaMP8f
UseAAVTagsExpressionMutationPromoterAvailable sinceSept. 23, 2022AvailabilityAcademic Institutions and Nonprofits only -
pAAV-hSyn-DIO {hCAR}off-{hM4Di-mCherry}on-W3SL
Plasmid#111397PurposeAAV vector with hSynapsin promoter, Cre-OFF hCAR (for efficient CAV-2 infection), Cre-ON hM4Di-mCherry (Gi-coupled DREADD for neuronal silencing), W3SL cassette (for maximize cloning capacity)DepositorInsertsUseAAVTagsMyc and mCherryExpressionMammalianMutationPromoterhSynapsinAvailable sinceJune 6, 2018AvailabilityAcademic Institutions and Nonprofits only -
pZac2.1 gfaABC1D-Glt1-eGFP
Plasmid#176862PurposeExpresses Glt-1 fused with GFP at the C-terminus in astrocytesDepositorInsertGlt1-eGFP
UseAAVTagsGFPExpressionBacterialMutationPromotergfaABC1DAvailable sinceApril 11, 2023AvailabilityAcademic Institutions and Nonprofits only -
pAAV-CAG-H2BmGreenLantern
Plasmid#177332PurposeTo express a bright monomeric green FP to label eucaryotic cell nuclei. To be used in clearing and other fluorescent microscope methods.DepositorInsertH2B (Hist1h2bq Rat)
UseAAVTagsmGreenLanternExpressionMammalianMutationThis fusion protein was optimized to the Human co…PromoterCAGAvailable sinceFeb. 4, 2022AvailabilityAcademic Institutions and Nonprofits only -
pAAV-CMV-EGFP-NLS
Plasmid#165441PurposeExpresses nuclear EGFP from CMV promoterDepositorInsertEGFP-NLS
UseAAVTagsNLSExpressionMammalianMutationPromoterCMVAvailable sinceJuly 13, 2021AvailabilityAcademic Institutions and Nonprofits only